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COVİD-19 tanısı almış hastaların immün plazma bağışına yönelik görüşleri ve etkileyen faktörler

Year 2025, Volume: 30 Issue: 2, 253 - 261, 29.05.2025

Nurdan Yalçın Atar , Semra Açıksöz , Zülfiye Ünal

https://doi.org/10.21673/anadoluklin.1591924

Abstract

Amaç: Bu çalışmanın amacı COVID-19 tanısı konulan hastaların immün plazma bağışına yönelik tutumlarını ve etkileyen faktörleri incelemektir.

Yöntemler: Bu kesitsel araştırma, COVID-19 kliniğinde tedavi edilen 125 hasta ile yüz yüze görüşme yöntemiyle gerçekleştirildi. Araştırma verileri, tanıtıcı bilgi formu ve İmmün Plazma Bağışına Yönelik Tutumlar Formu (İPBTF) ile toplandı.

Bulgular: Hastaların İPBTF puan ortalaması 2,97±0,47 idi (Min=2.06; Maks=4.71). “Yaş, eğitim durumu, çalışma durumu, birlikte yaşanılan kişi, önceki kan bağışı deneyimi, çevrede kan bağışında bulunan bireylerin varlığı, başka bir hastalığın varlığı ve COVID-19 immün plazma bağışıyla ilgili bilgi, immün plazma bağışına yönelik tutum düzeyindeki toplam değişimin %41,9’unu açıklamaktadır (R²=0,419).

Sonuç: COVID-19 hastaları immün plazma bağışına yönelik kararsız bir tutuma sahipti. Konu ile ilgili bilgi varlığı ve eğitim durumu COVID-19 hastalarının immün plazma bağışına yönelik tutumlarını etkilemektedir. Plazma bağışı teşvik edici politikalar, özellikle eğitim ve bilgi düzeyini artırmaya yönelik olmalıdır.

Keywords

COVID-19 kan vericiler pasif immünizasyon plazma tutum

References

  • Temel EN. Immune plasma applications in COVID-19 treatment. Med J SDU. 2021;(ozelsayi-1):87-92.
  • Bansal N, Raturi M, Bansal Y. COVID-19 vaccination: The impact on the selection criteria of the convalescent plasma donors. Transfus Clin Biol. 2021;28(3):308-9.
  • Focosi D, Franchini M, Pirofski LA, et al. COVID-19 Convalescent Plasma and Clinical Trials: Understanding Conflicting Outcomes. Clin Microbiol Rev. 2022;35(3):e0020021.
  • General Dırectorate of Health Servıces Blood and Blood Products Department Headship. (2020). COVID-19 Immune (Convalescent) Plasma Supply and Clinical Use Guidelines.Accessed 2023 Apr 19. https://shgmkanhizmetleridb.saglik.gov.tr/TR,72136/covid-19-immun-konvalesan-plazma-tedarik-ve-klinik-kullanim-rehberi-guncellendi.html#
  • Erkurt MA, Sarici A, Berber İ, Kuku İ, Kaya E, Özgül M. Life-saving effect of convalescent plasma treatment in covid-19 disease: Clinical trial from eastern Anatolia. Transfus Apher Sci. 2020;59(5):102867.
  • Hegerova L, Gooley TA, Sweerus KA, et al. Use of convalescent plasma in hospitalized patients with COVID-19: case series. Blood. 2020;136(6):759-62.
  • Hartman WR, Hess AS, Connor JP. Hospitalized COVID-19 patients treated with convalescent plasma in a mid-size city in the Midwest. Transl Med Commun. 2020;5(1):17.
  • Xia X, Li K, Wu L, et al. Improved clinical symptoms and mortality among patients with severe or critical COVID-19 after convalescent plasma transfusion. Blood. 2020;136(6):755-9.
  • Libster R, Pérez Marc G, Wappner D, et al. Early High-Titer Plasma Therapy to Prevent Severe Covid-19 in Older Adults. N Engl J Med. 2021;384(7):610-8.
  • Anichini G, Terrosi C, Gandolfo C, et al. SARS-CoV-2 Antibody Response in Persons with Past Natural Infection. N Engl J Med. 2021;385(1):90-2.
  • Li L, Tong X, Chen H, et al. Characteristics and serological patterns of COVID-19 convalescent plasma donors: optimal donors and timing of donation. Transfusion. 2020;60(8):1765-72.
  • Wang HE, Ostrosky-Zeichner L, Katz J, et al. Screening donors for COVID-19 convalescent plasma. Transfusion. 2021;61(4):1047-52.
  • Dhiman Y, Coshic P, Pandey HC, et al. Deterrents in recruitment of COVID-19 convalescent plasma donors: Experience from a hospital-based blood centre in India. Transfus Med. 2021;31(3):149-54.
  • Patel EU, Bloch EM, Grabowski MK, et al. Sociodemographic and behavioral characteristics associated with blood donation in the United States: a population-based study. Transfusion. 2019;59(9):2899-907.
  • Spratling R, Lawrence RH. Facilitators and Barriers to Minority Blood Donations: A Systematic Review. Nurs Res. 2019;68(3):218-26.
  • Shaz BH, Demmons DG, Hillyer KL, Jones RE, Hillyer CD. Racial differences in motivators and barriers to blood donation among blood donors. Arch Pathol Lab Med. 2009;133(9):1444-7.
  • Holloway K, Campbell C, Ali R, et al. A critical contribution in a time of crisis: Examining motivations and deterrents to COVID-19 convalescent plasma donation and future donation intentions among prospective Canadian donors. Transfus Med. 2022;32(5):351-65.
  • Kumar P, Sangma RD, Nerli LM, et al. Knowledge, Attitude, and Beliefs Regarding Convalescent Plasma Donation among COVID-19-recovered Patients at a Tertiary Care Center in India. Ind J Priv Psychiatry 2020;14(2):80–4.
  • Perenc L, Pęczkowski R. Knowledge and Attitudes of Young Adults Towards Donation of COVID-19 Convalescent Plasma and Its Therapeutic Properties. J Blood Med. 2021;12:709-17.
  • Yirmibeş DV. Knowledge, Attitudes and Behaviors of Society Towards Blood Donation in Turkey. Turk Health Lit J . 2021;2(1):16-25.
  • Lawshe CH. A quantitative approach to content validity. Personnel psychology. 1975:28(4);563-75.
  • Sümbüloğlu K, Sümbüloğlu V. (2009), Biyoistatistik. Ankara: Hatiboğlu Yayınevi.
  • Tabachnick BG, Fidell LS.(2013). Using multivariate statistics. 6th ed. Boston: Pearson.
  • George D, Mallery M. (2010), SPSS for Windows step by step: A simple guide and reference. 10th ed. Boston: Pearson;
  • Büyüköztürk Ş, Çokluk Ö, Köklü N. (2018), Sosyal bilimler için istatistik, Ankara: Pegem Akademi.
  • Kalkan, A. The effect of personal attitude, subjective norm and perceived behavioral control on entrepreneurial intention: an application on university students. Suleyman Demirel Univ Soc Sci. 2011;14:189-206.
  • Seghatchian J, Lanza F. WITHDRAWN: Convalescent plasma, an apheresis research project targeting and motivating the fully recovered COVID 19 patients: A rousing message of clinical benefit to both donors and recipients alike. Transfus Apher Sci. Published online April 22, 2020.
  • Masser BM, Ferguson E, Thorpe R, et al. Motivators of and barriers to becoming a COVID-19 convalescent plasma donor: A survey study. Transfus Med. 2021;31(3):176-85.
  • Salma N, Hossain MM, Yasmin S, et al. Factors influencing plasma donation behavior of COVID-19 recovered patients in Bangladesh: A pilot study. Health Sci Rep. 2022;6(1):e974.
  • Mecha A, Erchafo B. Blood donation intentions and predictors among Hosanna town dwellers, south nation nationality peoples region, Ethiopia. J Family Med Prim Care. 2022;11(9):5320-6.
  • Konstantinou I, Jones K. Investigating Gen Z attitudes to charitable giving and donation behaviour: Social media, peers and authenticity. J Philanthropy Mark. 2022;27(3):e1764.
  • Gloriani LE, Antejendra AML, Andres JSLF, et al. From victims to heroes: COVID-19 convalescent plasma donation awareness, knowledge, and willingness among selected respondents in the City of Manila. Eur Online J Nat Soc Sci. 2022;11(4):1-13.
  • Efteli E, Tuğrul E, Ergin S. Nursing Students’ Blood Donation Determination Of Attitudes. J Nurs Sci. 2018;1(1):5-9.
  • France CR, France JL, Himawan LK. What would it take to convince you to donate? A survey study of the relationship between motivators, barriers, and payment for whole blood, plasma, and platelet donation. Transfusion. 2022;62(6):1251-60.
  • Saeed S. Knowledge, attitude and practice of plasma donation among COVID-19 recovered patients in Punjab, Pakistan: a crosssectional study. Microbiolgy: Current Res. 2021; Sp. Iss.103:10.

COVID-19 patients’ attitudes and associated factors related to convalescent plasma donation

Year 2025, Volume: 30 Issue: 2, 253 - 261, 29.05.2025

Nurdan Yalçın Atar , Semra Açıksöz , Zülfiye Ünal

https://doi.org/10.21673/anadoluklin.1591924

Abstract

Aim: The aim of this study is to examine the attitudes of patients diagnosed with COVID-19 towards convalescent plasma donation and the factors influencing these attitudes.

Methods: This cross-sectional study was conducted through face-to-face interviews with 125 patients treated in a COVID-19 clinic. Data were collected using a descriptive information form and the Convalescent Plasma Donation Attitude Form (CPDAF).

Results: The mean CPDAF score of the patients was 2.97±0.47 (Min=2.06; Max=4.71). Age, education level, employment status, cohabitation status, previous blood donation experience, the presence of individuals in the environment who have donated blood, the presence of another illness, and knowledge about COVID-19 convalescent plasma donation explained 41.9% of the total variance in the convalescent plasma attitude (R2=0,419).

Conclusion: COVID-19 patients had an ambivalent attitude towards convalescent plasma donation. Information and education level significantly affect COVID-19 patients’ attitudes towards immune plasma donation. Plasma donation promotion policies should focus particularly on increasing education and information levels.

Keywords

Attitude blood donors COVID-19 passive immunization plasma

References

  • Temel EN. Immune plasma applications in COVID-19 treatment. Med J SDU. 2021;(ozelsayi-1):87-92.
  • Bansal N, Raturi M, Bansal Y. COVID-19 vaccination: The impact on the selection criteria of the convalescent plasma donors. Transfus Clin Biol. 2021;28(3):308-9.
  • Focosi D, Franchini M, Pirofski LA, et al. COVID-19 Convalescent Plasma and Clinical Trials: Understanding Conflicting Outcomes. Clin Microbiol Rev. 2022;35(3):e0020021.
  • General Dırectorate of Health Servıces Blood and Blood Products Department Headship. (2020). COVID-19 Immune (Convalescent) Plasma Supply and Clinical Use Guidelines.Accessed 2023 Apr 19. https://shgmkanhizmetleridb.saglik.gov.tr/TR,72136/covid-19-immun-konvalesan-plazma-tedarik-ve-klinik-kullanim-rehberi-guncellendi.html#
  • Erkurt MA, Sarici A, Berber İ, Kuku İ, Kaya E, Özgül M. Life-saving effect of convalescent plasma treatment in covid-19 disease: Clinical trial from eastern Anatolia. Transfus Apher Sci. 2020;59(5):102867.
  • Hegerova L, Gooley TA, Sweerus KA, et al. Use of convalescent plasma in hospitalized patients with COVID-19: case series. Blood. 2020;136(6):759-62.
  • Hartman WR, Hess AS, Connor JP. Hospitalized COVID-19 patients treated with convalescent plasma in a mid-size city in the Midwest. Transl Med Commun. 2020;5(1):17.
  • Xia X, Li K, Wu L, et al. Improved clinical symptoms and mortality among patients with severe or critical COVID-19 after convalescent plasma transfusion. Blood. 2020;136(6):755-9.
  • Libster R, Pérez Marc G, Wappner D, et al. Early High-Titer Plasma Therapy to Prevent Severe Covid-19 in Older Adults. N Engl J Med. 2021;384(7):610-8.
  • Anichini G, Terrosi C, Gandolfo C, et al. SARS-CoV-2 Antibody Response in Persons with Past Natural Infection. N Engl J Med. 2021;385(1):90-2.
  • Li L, Tong X, Chen H, et al. Characteristics and serological patterns of COVID-19 convalescent plasma donors: optimal donors and timing of donation. Transfusion. 2020;60(8):1765-72.
  • Wang HE, Ostrosky-Zeichner L, Katz J, et al. Screening donors for COVID-19 convalescent plasma. Transfusion. 2021;61(4):1047-52.
  • Dhiman Y, Coshic P, Pandey HC, et al. Deterrents in recruitment of COVID-19 convalescent plasma donors: Experience from a hospital-based blood centre in India. Transfus Med. 2021;31(3):149-54.
  • Patel EU, Bloch EM, Grabowski MK, et al. Sociodemographic and behavioral characteristics associated with blood donation in the United States: a population-based study. Transfusion. 2019;59(9):2899-907.
  • Spratling R, Lawrence RH. Facilitators and Barriers to Minority Blood Donations: A Systematic Review. Nurs Res. 2019;68(3):218-26.
  • Shaz BH, Demmons DG, Hillyer KL, Jones RE, Hillyer CD. Racial differences in motivators and barriers to blood donation among blood donors. Arch Pathol Lab Med. 2009;133(9):1444-7.
  • Holloway K, Campbell C, Ali R, et al. A critical contribution in a time of crisis: Examining motivations and deterrents to COVID-19 convalescent plasma donation and future donation intentions among prospective Canadian donors. Transfus Med. 2022;32(5):351-65.
  • Kumar P, Sangma RD, Nerli LM, et al. Knowledge, Attitude, and Beliefs Regarding Convalescent Plasma Donation among COVID-19-recovered Patients at a Tertiary Care Center in India. Ind J Priv Psychiatry 2020;14(2):80–4.
  • Perenc L, Pęczkowski R. Knowledge and Attitudes of Young Adults Towards Donation of COVID-19 Convalescent Plasma and Its Therapeutic Properties. J Blood Med. 2021;12:709-17.
  • Yirmibeş DV. Knowledge, Attitudes and Behaviors of Society Towards Blood Donation in Turkey. Turk Health Lit J . 2021;2(1):16-25.
  • Lawshe CH. A quantitative approach to content validity. Personnel psychology. 1975:28(4);563-75.
  • Sümbüloğlu K, Sümbüloğlu V. (2009), Biyoistatistik. Ankara: Hatiboğlu Yayınevi.
  • Tabachnick BG, Fidell LS.(2013). Using multivariate statistics. 6th ed. Boston: Pearson.
  • George D, Mallery M. (2010), SPSS for Windows step by step: A simple guide and reference. 10th ed. Boston: Pearson;
  • Büyüköztürk Ş, Çokluk Ö, Köklü N. (2018), Sosyal bilimler için istatistik, Ankara: Pegem Akademi.
  • Kalkan, A. The effect of personal attitude, subjective norm and perceived behavioral control on entrepreneurial intention: an application on university students. Suleyman Demirel Univ Soc Sci. 2011;14:189-206.
  • Seghatchian J, Lanza F. WITHDRAWN: Convalescent plasma, an apheresis research project targeting and motivating the fully recovered COVID 19 patients: A rousing message of clinical benefit to both donors and recipients alike. Transfus Apher Sci. Published online April 22, 2020.
  • Masser BM, Ferguson E, Thorpe R, et al. Motivators of and barriers to becoming a COVID-19 convalescent plasma donor: A survey study. Transfus Med. 2021;31(3):176-85.
  • Salma N, Hossain MM, Yasmin S, et al. Factors influencing plasma donation behavior of COVID-19 recovered patients in Bangladesh: A pilot study. Health Sci Rep. 2022;6(1):e974.
  • Mecha A, Erchafo B. Blood donation intentions and predictors among Hosanna town dwellers, south nation nationality peoples region, Ethiopia. J Family Med Prim Care. 2022;11(9):5320-6.
  • Konstantinou I, Jones K. Investigating Gen Z attitudes to charitable giving and donation behaviour: Social media, peers and authenticity. J Philanthropy Mark. 2022;27(3):e1764.
  • Gloriani LE, Antejendra AML, Andres JSLF, et al. From victims to heroes: COVID-19 convalescent plasma donation awareness, knowledge, and willingness among selected respondents in the City of Manila. Eur Online J Nat Soc Sci. 2022;11(4):1-13.
  • Efteli E, Tuğrul E, Ergin S. Nursing Students’ Blood Donation Determination Of Attitudes. J Nurs Sci. 2018;1(1):5-9.
  • France CR, France JL, Himawan LK. What would it take to convince you to donate? A survey study of the relationship between motivators, barriers, and payment for whole blood, plasma, and platelet donation. Transfusion. 2022;62(6):1251-60.
  • Saeed S. Knowledge, attitude and practice of plasma donation among COVID-19 recovered patients in Punjab, Pakistan: a crosssectional study. Microbiolgy: Current Res. 2021; Sp. Iss.103:10.
There are 35 citations in total.

Details

Primary Language English
Subjects Nursing (Other)
Journal Section ORIGINAL ARTICLE
Authors

Nurdan Yalçın Atar 0000-0002-6318-3882

Semra Açıksöz 0000-0003-0451-698X

Zülfiye Ünal 0009-0004-5992-271X

Publication Date May 29, 2025
Submission Date November 27, 2024
Acceptance Date March 26, 2025
Published in Issue Year 2025 Volume: 30 Issue: 2

Cite

Vancouver Yalçın Atar N, Açıksöz S, Ünal Z. COVID-19 patients’ attitudes and associated factors related to convalescent plasma donation. Anatolian Clin. 2025;30(2):253-61.
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