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Evaluation of Pregnancy Complications in Women with Polycystic Ovarian Syndrome Who Have Undergone In Vitro Fertilization (IVF)

Year 2022, Volume: 75 Issue: 2, 279 - 285, 30.06.2022

Berna Şermin Kılıç

Abstract

Objectives: The aim of the study is to compare the pregnancy complications including particularly gestational diabetes mellitus (GDM) and
preeclampsia of women having polycystic ovarian syndrome (PCOS), with normal pregnancy complications.

Materials and Methods: To investigate the impact of PCOS on pregnancy complications, we retrospectively compared the pregnant patients
(diagnosed with PCOS) with normal pregnant patients who became pregnant using the intra cytoplasmic sperm injection method, having same
age and body mass index, at İstanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, Department of Obstetrics and Gynecology, In Vitro
Fertilization Unit between 2002 and 2011.

Results: When the patients diagnosed with PCOS and control group were compared in terms of the pregnancy complications, early pregnancy loss
and GDM were found to be statistically significant. (respectively p=0.005, p=0.013). The interaction between early pregnancy loss and gestational
diabetes with age, body mass index, gestational weight gain, fasting glucose, fasting insulin and Homeostasis Model Assessment (HOMA-IR) values
were investigated with the Spearman correlation analysis. While the gestational weight gain was negatively correlated with early pregnancy loss;
age, fasting glucose, fasting insulin and HOMA-IR were positively correlated with gestational diabetes (p=0.001 for early pregnancy loss; p=0.005,
p=0.001, p=0.005, p=0.001 respectively for GDM).

Conclusion: Early pregnancy loss and GDM are seen more often in polycystic ovary syndrome. Early pregnancy loss of pregnant women with PCOS
was found to be high independent of the blood sugar regulation parameters of the patients.

Keywords

Polycstic Ovarian Syndrome GDM Preeclampsia Early Pregnancy Loss Pregnancy Complications

Ethical Statement

Etik Etik Kurul Onayı: İstanbul Üniversitesi-Cerrahpaşa, Cerrahpaşa Tıp Fakültesi Etik Kurulu’ndan (tarih: 22.06.2012, karar no: 3221) onay alınmıştır. Hasta Onayı: Çalışmamız retrospektif olduğu için hastalardan yazılı onam alınamamıştır. Hakem Değerlendirmesi: Editörler kurulu dışında olan kişiler tarafından değerlendirilmiştir.

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There are 32 citations in total.

Details

Primary Language English
Subjects Obstetrics and Gynaecology
Journal Section Articles
Authors

Berna Şermin Kılıç 0000-0002-0103-0709

Publication Date June 30, 2022
Published in Issue Year 2022 Volume: 75 Issue: 2

Cite

APA Kılıç, B. Ş. (2022). Evaluation of Pregnancy Complications in Women with Polycystic Ovarian Syndrome Who Have Undergone In Vitro Fertilization (IVF). Ankara Üniversitesi Tıp Fakültesi Mecmuası, 75(2), 279-285. https://doi.org/10.4274/atfm.galenos.2021.25349
AMA Kılıç BŞ. Evaluation of Pregnancy Complications in Women with Polycystic Ovarian Syndrome Who Have Undergone In Vitro Fertilization (IVF). Ankara Üniversitesi Tıp Fakültesi Mecmuası. June 2022;75(2):279-285. doi:10.4274/atfm.galenos.2021.25349
Chicago Kılıç, Berna Şermin. “Evaluation of Pregnancy Complications in Women With Polycystic Ovarian Syndrome Who Have Undergone In Vitro Fertilization (IVF)”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 75, no. 2 (June 2022): 279-85. https://doi.org/10.4274/atfm.galenos.2021.25349.
EndNote Kılıç BŞ (June 1, 2022) Evaluation of Pregnancy Complications in Women with Polycystic Ovarian Syndrome Who Have Undergone In Vitro Fertilization (IVF). Ankara Üniversitesi Tıp Fakültesi Mecmuası 75 2 279–285.
IEEE B. Ş. Kılıç, “Evaluation of Pregnancy Complications in Women with Polycystic Ovarian Syndrome Who Have Undergone In Vitro Fertilization (IVF)”, Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 75, no. 2, pp. 279–285, 2022, doi: 10.4274/atfm.galenos.2021.25349.
ISNAD Kılıç, Berna Şermin. “Evaluation of Pregnancy Complications in Women With Polycystic Ovarian Syndrome Who Have Undergone In Vitro Fertilization (IVF)”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 75/2 (June 2022), 279-285. https://doi.org/10.4274/atfm.galenos.2021.25349.
JAMA Kılıç BŞ. Evaluation of Pregnancy Complications in Women with Polycystic Ovarian Syndrome Who Have Undergone In Vitro Fertilization (IVF). Ankara Üniversitesi Tıp Fakültesi Mecmuası. 2022;75:279–285.
MLA Kılıç, Berna Şermin. “Evaluation of Pregnancy Complications in Women With Polycystic Ovarian Syndrome Who Have Undergone In Vitro Fertilization (IVF)”. Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 75, no. 2, 2022, pp. 279-85, doi:10.4274/atfm.galenos.2021.25349.
Vancouver Kılıç BŞ. Evaluation of Pregnancy Complications in Women with Polycystic Ovarian Syndrome Who Have Undergone In Vitro Fertilization (IVF). Ankara Üniversitesi Tıp Fakültesi Mecmuası. 2022;75(2):279-85.
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