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İKİ OLGU NEDENİYLE MALİGN HİPERTERMİ

Year 1993, Volume: 46 Issue: 4, 667 - 676, 31.12.1994

Ömer Kurtipek

Abstract

Bu makalede genel anestezi ile indüklenen iki MH olgusu sunuyorum ilk olguda anestezi tiyopental, süksinilkolin, N20/02 ve halotan ile sažlandl. Anestezinin sonlandlrllmasmdan hemen önce tasikardi, aritmiler, hipertansiyon ve hipertermi gelisti. Derin metabolik ve respiratuar asidoz ve CPK yüksekliäi ile tani desteklendi, Îkinci olguda ise 02 ve halotan ile indüksiyonun ardlndan süksinilkolin uygulandl Uygulamanm hemen ardmdan masseter kas spazrm ve yaygln rijidite gelisti. Derin metabolik asidoz ve CPK yüksekliži gözlendi. Tedavi % 100 02 ile hiperventilasyon, eksternal sogutma ve metabolik asidozun NaHC03 ile düzeltilmesi seklindeydi. Aynl zamanda renal fonksiyonlar desteklendi.

Keywords

malign hipertermi malign hipertermi

Ethical Statement

-

Supporting Institution

-

Project Number

-

Thanks

-

References

  • l. Allen GC Henry R Rhaeochromocytoma presenting on acute malignant hypert hermia-a diagnostic challenge. Can J Anaesth 37; 5 • 593-595, 1990
  • 2. Bennet MH Wainwright AP : Acute thyroid crisis on induction of anaesthesia. Anaesthesia 44 28-30, 1989.
  • 3. Dubrow TJ Wackym PA imad HA Moore TC : Malignant hyperthermia : Experience in the prospective management of eight children. Journal of Pediatric Surgery 24 : 163-166, 1989.
  • 4. Emmanuel ER : Multiple anaesthetic for a malignant hyperthermia susceptible patient. Anaesthesia 43 : 666-670, 1988.
  • 5. Fletcher JE Rosenherg H Lizzo FH : Effects of droperidol, haloperidol and ketarnine on halothane, succinyW101ine and caffeine contractures : Implications for malignant hyperthermia. Acta Anaesthesiol Scand 33 : 187-192, 1989.
  • 6. Fletcher JE Rosenberg H : In vitro interection between halothane and succinylcholine in human skeletal muscle : Implications for malignant. hyperthermia and masseter muscle rigidity. Anesthesiology 63 • 190-194, 1985.
  • 7. Hackl W Mavritz W Schemper M Sporn P Steinbereithner K : Prediction of malignant hyperthermia susceptibil ity ; Statistical evaluation of clinical signs. British Journal of Anaesthesia 64 : 425-429, 1990.
  • 8. Hall DB Mohla ME Muldoon SM : Factitious malignant hyperthermia. Anesth Analg 67 : 1005-1007, 1988.
  • 9. Horber RK Adnet P Guevart E Theunynck D Lestavel P Neuroleptic malignant syndrome and malignant hyperthermia, Br. J. Anaesth 59 : 1554-1556, 1987.
  • 10. Horiako T Sone T Toda H Mivake C : Malignant hyperthermia in a hemodialysis patient. Anesth Analg 69 : 119-121, 1989.
  • 11. Muldoon SM Boggs SD Freas W • Ma)ignant hyperthermia. In Shoemaker WC Ayres S. Grenvik A, Halbrook PR, Thompson WL (eds) : Textbook of Critical care. Philadelphia, W.B. Saunders Company, pp 109-1.14, 1989
  • 12. Ording H : Incidence of malignant i,ypertherimia in Denmark. Anesth Analg 64 : 700-704, 1985.
  • 13 Simons ML Goldman E : Atypical malignant hyperthermia with persistent hyperkalaemia during renal transplantation. Can J Anaesth 35 : 409-412, 1988.
  • 14. Tulunay M Anadol E Saygln B Yllmaz O Çanaiç,1 N El,verdi N Arsan M : Malignant hyperthermia : A case report. Turkish Journal of Research in Medical Sciences 5 : 553-558, 1986.

two cases of malignant hypertermia

Year 1993, Volume: 46 Issue: 4, 667 - 676, 31.12.1994

Ömer Kurtipek

Abstract

In this paper we report 2 cases of MH induced by general anaesthesic. In the first case anesthesia was induced with thiopental succinlycholine, N2O/02 and halothane. Just before the termination of anesthesia tachicardia, aritmia, hypertension, hypertermia develophed. Diagnosis was confirmed by the detection of severe metabolic and respiratory acidosis, elevation of CPK. In the second case after the induction with O2 and halothane succinylcholine was administered. Just after the administration, masseter muscle spasm and generalized rigidite developed, severe metabolic acidosis and elevation of CPK were observed. Theraph consisted of hyperventilation with 100 % O2 external body cooling, correction of metabolic acidosis with NaHCO3. Also renal functions were supported.

Keywords

malign hypertermia malign hypertermia

Ethical Statement

-

Supporting Institution

-

Project Number

-

Thanks

-

References

  • l. Allen GC Henry R Rhaeochromocytoma presenting on acute malignant hypert hermia-a diagnostic challenge. Can J Anaesth 37; 5 • 593-595, 1990
  • 2. Bennet MH Wainwright AP : Acute thyroid crisis on induction of anaesthesia. Anaesthesia 44 28-30, 1989.
  • 3. Dubrow TJ Wackym PA imad HA Moore TC : Malignant hyperthermia : Experience in the prospective management of eight children. Journal of Pediatric Surgery 24 : 163-166, 1989.
  • 4. Emmanuel ER : Multiple anaesthetic for a malignant hyperthermia susceptible patient. Anaesthesia 43 : 666-670, 1988.
  • 5. Fletcher JE Rosenherg H Lizzo FH : Effects of droperidol, haloperidol and ketarnine on halothane, succinyW101ine and caffeine contractures : Implications for malignant hyperthermia. Acta Anaesthesiol Scand 33 : 187-192, 1989.
  • 6. Fletcher JE Rosenberg H : In vitro interection between halothane and succinylcholine in human skeletal muscle : Implications for malignant. hyperthermia and masseter muscle rigidity. Anesthesiology 63 • 190-194, 1985.
  • 7. Hackl W Mavritz W Schemper M Sporn P Steinbereithner K : Prediction of malignant hyperthermia susceptibil ity ; Statistical evaluation of clinical signs. British Journal of Anaesthesia 64 : 425-429, 1990.
  • 8. Hall DB Mohla ME Muldoon SM : Factitious malignant hyperthermia. Anesth Analg 67 : 1005-1007, 1988.
  • 9. Horber RK Adnet P Guevart E Theunynck D Lestavel P Neuroleptic malignant syndrome and malignant hyperthermia, Br. J. Anaesth 59 : 1554-1556, 1987.
  • 10. Horiako T Sone T Toda H Mivake C : Malignant hyperthermia in a hemodialysis patient. Anesth Analg 69 : 119-121, 1989.
  • 11. Muldoon SM Boggs SD Freas W • Ma)ignant hyperthermia. In Shoemaker WC Ayres S. Grenvik A, Halbrook PR, Thompson WL (eds) : Textbook of Critical care. Philadelphia, W.B. Saunders Company, pp 109-1.14, 1989
  • 12. Ording H : Incidence of malignant i,ypertherimia in Denmark. Anesth Analg 64 : 700-704, 1985.
  • 13 Simons ML Goldman E : Atypical malignant hyperthermia with persistent hyperkalaemia during renal transplantation. Can J Anaesth 35 : 409-412, 1988.
  • 14. Tulunay M Anadol E Saygln B Yllmaz O Çanaiç,1 N El,verdi N Arsan M : Malignant hyperthermia : A case report. Turkish Journal of Research in Medical Sciences 5 : 553-558, 1986.
There are 14 citations in total.

Details

Primary Language Turkish
Subjects Anaesthesiology
Journal Section Articles
Authors

Ömer Kurtipek

Project Number -
Publication Date December 31, 1994
Published in Issue Year 1993 Volume: 46 Issue: 4

Cite

APA Kurtipek, Ö. (1994). İKİ OLGU NEDENİYLE MALİGN HİPERTERMİ. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 46(4), 667-676.
AMA Kurtipek Ö. İKİ OLGU NEDENİYLE MALİGN HİPERTERMİ. Ankara Üniversitesi Tıp Fakültesi Mecmuası. December 1994;46(4):667-676.
Chicago Kurtipek, Ömer. “İKİ OLGU NEDENİYLE MALİGN HİPERTERMİ”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 46, no. 4 (December 1994): 667-76.
EndNote Kurtipek Ö (December 1, 1994) İKİ OLGU NEDENİYLE MALİGN HİPERTERMİ. Ankara Üniversitesi Tıp Fakültesi Mecmuası 46 4 667–676.
IEEE Ö. Kurtipek, “İKİ OLGU NEDENİYLE MALİGN HİPERTERMİ”, Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 46, no. 4, pp. 667–676, 1994.
ISNAD Kurtipek, Ömer. “İKİ OLGU NEDENİYLE MALİGN HİPERTERMİ”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 46/4 (December 1994), 667-676.
JAMA Kurtipek Ö. İKİ OLGU NEDENİYLE MALİGN HİPERTERMİ. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1994;46:667–676.
MLA Kurtipek, Ömer. “İKİ OLGU NEDENİYLE MALİGN HİPERTERMİ”. Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 46, no. 4, 1994, pp. 667-76.
Vancouver Kurtipek Ö. İKİ OLGU NEDENİYLE MALİGN HİPERTERMİ. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1994;46(4):667-76.