Research Article
Year 1993,
Volume: 46 Issue: 2, 253 - 268, 30.06.1993
Abstract
Retinoblastoma is the most common ocular malignancy of childhood, This tumor originates from the neuroectodermal cells that is located on external and internal retinal nuclear layers. Although inheritance was thought to be an important factor, exact aetiology haven't found yet. Differantial diagnosis must be thought when lococori and strabismus was encountered on clinical examination. Exact diagnosis is established only after pathologic examination, Thus, further analysis must be done before the operation. Enucleation and cutting a long segment as long as possible of optic nerve has a positive effect on prognosis.
In this paper we discussed the retinoblastoma on the epidemiologic, genetic, clinic, diagnostic, prognostic and differantial diagnostic features,
Supporting Institution
-
Project Number
-
Thanks
-
References
- 1. Abramson HD Ronner HJ Ellsworth RM : Second tumors in non irradiated bilateral retinoblastoma, Am. J. Opthalmol. 87 : 624-7, 1959
- 2. Bilaniuk LT Atlas SW Zimmerman RA : Magnetic Rezonance imaging of the Orbit. In the radiologic clinies of North America, ed. by Mafee MF. 25 : 3, 509-28, 1987.
- 3. Cotran RS Kumar V Robbins SL . Pathologic Basis of Disease, 4th ed. WB Saunders Comp. pp 1462-4, 1989,
- 4. Ellsworth RM : Retinoblastoma. In Clinical Ophtalmology, ed. by Duane TD, Jaeger BA. Harper and Row Publishers, Philadelphia, 3 (35) : 1-18, 1986.
- 5. Herman MM et al: Neuroblastic differantiation potential of the human retinoblastoma cell lines Y-79 and WERI-Rbl maintained an organ culture system. An immunochemical, electron microscopic and biochemical study. Am J Pathol, 134 ; 1, 115-32, 1989,
- 6. Hogan MJ Zimmerman LE : Opthalmic Pathology. An Atlas and Textbook. Sec. ed. WB Saunders Comp., Philadelphia, 1962.
- 7. Jakobiec BA Rootman J Jones IS : Secondary and metastatic tumors of the orbit, In Clinical Ophtalmology. ed. by Duane TD, Jaeger Harper and Row Publishers, Philadelphia, 2 (46) ; 1-7, 1986.
- 8. Kansky JJ - Clinical Opthalmology. Butterworths Co. World Student Reprints ed., 1987.
- 9. Kissane JM : Anderson’s Pathology. eighth ed. The Mosby Comp. St. Louis, vol. one, pp 974-7, 1985,
- 10. Mafee MF Goidberg FM Greenwarld MJ Schulman J Malmed A and Flander AE ; Retinoblastoma and simulating lesions : role of OT and MR imaging. In the radiologic clinics of North America. Bd. by Mafee MF, 25 : 4, 667-99, 1987.
- 11. McCartney A Oliver JM Kingston JE and Hungerford JL : years of retinoblastomo. Into the fifth age, Eye Supp! 2, 13-13, 1988.
- 12. Michelson IB Felberg NT and Shields JA : Carcinoembryonic antigen its role in the evaluation of intraccular malignancies. Arch. Ophtalmol. 94 : 414-6, 1976.
- 13. Michelson JB Felberg NT and Shields JA . Fetal entigens in retinoblastoma, cancer 37 : 719-23, 1976.
- 14. Newell FW : Ophtalmology. Principles and concepts, Sixth ed. The Mosby Comp. St. Luois, 1986.
- 15. Pendergrass TW Davies S : Incidence of retinoblastoma in the United States. Arch. Ophtalmol. 98 : 1204-10, 1980.
- 16. Reese AB : Tumors of the eye and adnexa. Atlas of tumor Pathology. AFIP. Washington DC, 1956.
- 17. Roberts DF Keen MD Aherne CES and Long DR : Immunogenetic studies in retinoblastoma, Br. J. Ophtalmol. 70 : 686-91, 1996.
- 18. Schiaegel TF , Differantial diagnosis (Masquerade syndromes} In clinical ophtalmology, ed. by Duane TD, Jaeger EA. Harper and Row Publisher, Philadelphia, 4; 59-3, 1986,
- 19. Shields JA : Diagnosis and management of intracctiler Tumors. The CV Mosby Comp, pp 437-96, 1983.
- 20. Shields JA Lerner HA and Felberg NT : Aqueous cytoolgy and enzymes in nematode endoftalmitis. Am. J. Ophtalmol. 84 ; 319-22, 1977.
- 21. Shields JA Michelson JB Leonard BC and Sarin LK : B Scan ultrasonograpy in diagnosis of atipical retinoblastomas. Can. J. Ophtalmol ,11 : 42-51, 1976,
- 22. Sterns GK Coleman DJ Ellsworth RM : Ultrasonographic characteristics of re. tinoblastoma, Am. J. Ophtalmol. 78 . 608, 1974.
- 23. Tilj JWM Koornneef L: Fine Needle aspiration biopsy in orbital tumours. Br, J. Ophtalmol. 75 : 491-2, 1991.
- 24. Tolentino FI and Tablante NT : Cryothrapy of retinoblastoma, Arch Ophtalmol. 87 : 52-5, 1977,
- 25. Tsukahara 1: A histopathological study on the prognosis and radiosensitivity of retinoblastoma. Arch. Ophtalmol. 63 : 1005, 1960.
- 26. Winter JB ; The effect of photedynamic therapy on a retinoblastoma like tumour. Acta Optalmol. Supp. 197 - 68, 1990.
- 27. Zimmerman LE Sobin LH : Histological typing of tumours of the eye and its adnexa. World Health Organization, Genava, 1980.
Year 1993,
Volume: 46 Issue: 2, 253 - 268, 30.06.1993
Abstract
Retinanin eksternal veya internal nükleer tabakasındaki fotoraseptérik diferansiyasyon gösteren noroektodermal hücrelerden kaynaklanan retinoblastom, çocukluk çağ oküler maligniteleri arasında en sık rastladığımız tumérdiir. Kalıtım önemli roli oldugu düşünülmesine kargin etyoloji tam olarak saptanamamıştır. Klinik olarak lékokori ve sasilik saptadığımız çocuklarda retinoblastom dtsintilmeli ve taklit eden lezyonlarla ayinici tanis1 yapilmalidir, Ancak kesin teşhis operasyon sonrası patolojik inceleme ile konulabilmektedir. Bu nedenle de operasyon 6ncesi mutlaka ileri tetkiklerle arastirilmasi1 gerekmektedir. Tedavide entikleasyonla birlikte optik sinirin olabildiğince uzun bir segment olarak girilmesi prognozu artıran bir yöntemdir.
Biz bu çalışmada çocukluk gag oküler maligniteleri arasında en sık görülen retinoblastom olgusunu etyolojik, epidemiyolojik, genetik, klinik, diagnostik, prognostik ve ayırıcı tanımsal 6ézellikleri dikkate alınarak literatürler ve klasik bilgiler 1:8mda tartıştık.
Project Number
-
References
- 1. Abramson HD Ronner HJ Ellsworth RM : Second tumors in non irradiated bilateral retinoblastoma, Am. J. Opthalmol. 87 : 624-7, 1959
- 2. Bilaniuk LT Atlas SW Zimmerman RA : Magnetic Rezonance imaging of the Orbit. In the radiologic clinies of North America, ed. by Mafee MF. 25 : 3, 509-28, 1987.
- 3. Cotran RS Kumar V Robbins SL . Pathologic Basis of Disease, 4th ed. WB Saunders Comp. pp 1462-4, 1989,
- 4. Ellsworth RM : Retinoblastoma. In Clinical Ophtalmology, ed. by Duane TD, Jaeger BA. Harper and Row Publishers, Philadelphia, 3 (35) : 1-18, 1986.
- 5. Herman MM et al: Neuroblastic differantiation potential of the human retinoblastoma cell lines Y-79 and WERI-Rbl maintained an organ culture system. An immunochemical, electron microscopic and biochemical study. Am J Pathol, 134 ; 1, 115-32, 1989,
- 6. Hogan MJ Zimmerman LE : Opthalmic Pathology. An Atlas and Textbook. Sec. ed. WB Saunders Comp., Philadelphia, 1962.
- 7. Jakobiec BA Rootman J Jones IS : Secondary and metastatic tumors of the orbit, In Clinical Ophtalmology. ed. by Duane TD, Jaeger Harper and Row Publishers, Philadelphia, 2 (46) ; 1-7, 1986.
- 8. Kansky JJ - Clinical Opthalmology. Butterworths Co. World Student Reprints ed., 1987.
- 9. Kissane JM : Anderson’s Pathology. eighth ed. The Mosby Comp. St. Louis, vol. one, pp 974-7, 1985,
- 10. Mafee MF Goidberg FM Greenwarld MJ Schulman J Malmed A and Flander AE ; Retinoblastoma and simulating lesions : role of OT and MR imaging. In the radiologic clinics of North America. Bd. by Mafee MF, 25 : 4, 667-99, 1987.
- 11. McCartney A Oliver JM Kingston JE and Hungerford JL : years of retinoblastomo. Into the fifth age, Eye Supp! 2, 13-13, 1988.
- 12. Michelson IB Felberg NT and Shields JA : Carcinoembryonic antigen its role in the evaluation of intraccular malignancies. Arch. Ophtalmol. 94 : 414-6, 1976.
- 13. Michelson JB Felberg NT and Shields JA . Fetal entigens in retinoblastoma, cancer 37 : 719-23, 1976.
- 14. Newell FW : Ophtalmology. Principles and concepts, Sixth ed. The Mosby Comp. St. Luois, 1986.
- 15. Pendergrass TW Davies S : Incidence of retinoblastoma in the United States. Arch. Ophtalmol. 98 : 1204-10, 1980.
- 16. Reese AB : Tumors of the eye and adnexa. Atlas of tumor Pathology. AFIP. Washington DC, 1956.
- 17. Roberts DF Keen MD Aherne CES and Long DR : Immunogenetic studies in retinoblastoma, Br. J. Ophtalmol. 70 : 686-91, 1996.
- 18. Schiaegel TF , Differantial diagnosis (Masquerade syndromes} In clinical ophtalmology, ed. by Duane TD, Jaeger EA. Harper and Row Publisher, Philadelphia, 4; 59-3, 1986,
- 19. Shields JA : Diagnosis and management of intracctiler Tumors. The CV Mosby Comp, pp 437-96, 1983.
- 20. Shields JA Lerner HA and Felberg NT : Aqueous cytoolgy and enzymes in nematode endoftalmitis. Am. J. Ophtalmol. 84 ; 319-22, 1977.
- 21. Shields JA Michelson JB Leonard BC and Sarin LK : B Scan ultrasonograpy in diagnosis of atipical retinoblastomas. Can. J. Ophtalmol ,11 : 42-51, 1976,
- 22. Sterns GK Coleman DJ Ellsworth RM : Ultrasonographic characteristics of re. tinoblastoma, Am. J. Ophtalmol. 78 . 608, 1974.
- 23. Tilj JWM Koornneef L: Fine Needle aspiration biopsy in orbital tumours. Br, J. Ophtalmol. 75 : 491-2, 1991.
- 24. Tolentino FI and Tablante NT : Cryothrapy of retinoblastoma, Arch Ophtalmol. 87 : 52-5, 1977,
- 25. Tsukahara 1: A histopathological study on the prognosis and radiosensitivity of retinoblastoma. Arch. Ophtalmol. 63 : 1005, 1960.
- 26. Winter JB ; The effect of photedynamic therapy on a retinoblastoma like tumour. Acta Optalmol. Supp. 197 - 68, 1990.
- 27. Zimmerman LE Sobin LH : Histological typing of tumours of the eye and its adnexa. World Health Organization, Genava, 1980.
There are 27 citations in total.
Details
| Primary Language | English |
|---|---|
| Subjects | Pathology |
| Journal Section | Articles |
| Authors | |
| Project Number | - |
| Publication Date | June 30, 1993 |
| Published in Issue | Year 1993 Volume: 46 Issue: 2 |
