Research Article
BibTex RIS Cite

Kanserli Mide ve Meme Dokularında Demir, Bakır, Çinko ve Magnezyum Konsantrasyonlarının Tayini

Year 1991, Volume: 44 Issue: 4, 529 - 536, 31.12.1991

Orhan Canbolat

Abstract

Bu calismada, kanserli ve kanserli olmayan mide ve meme dokularinda demir, bakir, ¢mkb ve magnezyum konsantrasyonlari tayin edilmis ve sonuglar istatistiki olarak mukayese edilmistir. Mide dokusundaki elementlerin ortalama degerleri ile ilgili olarak, kanserli doku ve kanserli olmayan doku arasinda istatistiksel
olarak anlamh farklihklar bulunamamustir. Buna karsilik kanserli meme dokusunda bakir ve demir konsantrasyonlarinin, kanserli olmayan dokulara nazaran daha yüksek oldugu tespit edilmistir. Benzer sekilde, kanserli meme dokusunda element oranlarinin degistigi, elementler arasi iliskilerin bozuldugu gézlenmistir.

Keywords

KANSER DNA RNA polimeraz

Ethical Statement

-

Supporting Institution

-

Project Number

-

Thanks

-

References

  • 1. Abdulla M Biorklund A Mathur A and Wallerius K : The Role of Zinc in Experimental and Human Oral Cancer. 1978 University of Lund Press, Sweden, Page : 111-114.
  • 2. Breiter DN Diasio RB Niefeld JP Roush ML and Rosenberg SA : Serum copper and zinc measurements in patients with osteogenic carcinoma, Cancer 42 : 598-602; 1978.
  • 3. Hargovcic M Tessmer CF Thomas FB Fuller 1M Gamble JF and Schullenberger CC : Significance of serum copper levels in adult patients with Hodgkin’s Disease. Cancer 31 : 1337-1345; 1973.
  • 4. Heck JD and Costa M: Influence of surface charge and dissolution on the selective phagocytosis of potentially carcinogenic particulate metal compounds. Cancer Res 43 : 5652-5656; 1983.
  • 5. Hsi -A Johnson NP San-Sebastian J O'Neill JP Rahn RO and Forbes NL : Quantitative mammalian cell mutagenesis and a study of mutagenic potential of metallic compounds. In : Trace Metals in Health and Disease. 1979 Raven Press, N.Y. page : 55-69.
  • 6. Issel F Macfadyen BV Gum ET Valdivieso M Dudrick SJ and Bodey GF : Serum zinc levels in lung cancer patients. Cancer 47 : 18451848; 1981.
  • 7. Janes JM McCall JT and Elveback LR : Trace metals in human osteogenic carcinoma, Mayo Clin Proc. 47 : 476-478; 1972.
  • 8. deJorge FB Paiva L Moin D and Da Nova R : Biochemical studies on copper, copper oxidase, magnesium, sulfur, calcium and phosphorus in cancer of the larynx. Acta Otolaryngol 61 : 454-458; 1966.
  • 9. Karcioglu Z Karcioglu G Sarper RM and Hargovcic M : Zinc and copper in neoplastic diseases. In : Zinc and Copper in Medicine. Karcioglu, Z. and Sarper , R.M [eds]1980 Charles C. Thomas Inc., Springfield page : 464-534.
  • 10. Kirkbright GF : Atomic absorption spectroscopy in elemental analysis of biological materials. International Atomic Energy Agency, Technical Report Series, No. 197 : 141-145; 1980.
  • 11. Mulay IL Roy R Knox BE Suhr NH and Delaney WE : Trace metal analysis of cancerous and non-cancerous human tissue, J Natl Cancer Inst 47; 1-18; 1971.
  • 12. . Price WJ : Analytical Atomic Absorption Spectroscopy. 1974 Heiden and Son Ltd., London. Page : 42-44.
  • 13. Rizk SL and Sky-Peck HH : Comparison between concentrations of trace elements in normal and neoplastic human breast tissue. Cancer Res 44 : 5490- 5394; 1984.
  • 14. Santaliquido PM and Southwick HW : Trace metal levels in cancer of the, breast. Surg Gynecol Obstetr 142 ; 65-70; 1976.
  • 15. Schroder HA Nason AP Tipton IH and Balasa JJ : Essential trace metals in man : Zinc. J Chronic Dis 20: 179-186; 1967.
  • 16. Schrauzer GN : The role of trace elements in the etioldgy of cancer. In : Trace Element Analytical Chemistry in Medicine and Biology. 1980 de Gruyter, N.Y. page : 183-198. 17. Scwartz MK : Role of trace elements in cancer. Cancer Res 35 : 3481 3487, 1987.
  • 15. Sigel H led.) : Metal Ions in Biological Systems : Carcinogenicity and Metal Tons, 1980 Marcel Dekker Inc. N.Y. Vol. 10. Page : 132-148.
  • 16. Schrauzer GN : The role of trace elements in the etioldgy of cancer. In : Trace Element Analytical Chemistry in Medicine and Biology. 1980 de Gruyter, N.Y. page : 183-198.
  • 17. Scwartz MK : Role of trace elements in cancer. Cancer Res 35 : 3481 3487, 1987.
  • 18. Sigel H led.) : Metal Ions in Biological Systems : Carcinogenicity and Metal Tons, 1980 Marcel Dekker Inc. N.Y. Vol. 10. Page : 132-148.
  • 19. Sirover MA and Loeb LA : On the fidelity of DNA replication. Effect of metal activators during synthesis with avian myeloblastosis virus DNA polymerase. Biol Chem 252 : 3606-3610, 1977.
  • 20. Sky-Peck HH : Trace metals and neoplasia. Clin Physiol Biochem 4 : 111, 1986.
  • 21. Sunderman FW : Carcinogenic effects of metals. Fed Proc 37 : 40-46, 1979.
  • 22.Sunderman FW : Recent advances in metal carcinogenesis. Ann Clin Lab Sci 14 : 93-122, 1984,
  • 23. Sunderman FW ; Mechanisms of metal carcinogenesis, Biol Trace Element Kes 1: 64-86, 1979.
  • 24. Sunderman FW : Mechanism of metal carcinogenesis. In : The Clinical Bioc- hemistry of Carcinogenesis 1980 American Association of Clinical Chemists, Washington page : 265-297.
  • 25. Tani P and Kokkola K : Serum iron, copper and iron-binding capacity in bronchogenic pulmonary carcinoma, Scand J Hespirat Disease 80 : 121-128, 1972.
  • 26. Valcovic V : Analysis of Biological Material for Trace Elements Using X-Ray Spectroscopy. 1980 CRC Press Inc. Boca Raton. Page : 125-143.
  • 27. Vallee BL and Goldes A : The metallobiochemistry of zinc enzymes. Adv Enz 56 : 283-431, 1984.
  • 28. Weinstein IB : Current concepts in mechanisms of clinical carcinogenesis. Bull N.Y. Acad Med 54 : 366-383, 1978

Kanserli Mide ve Meme Dokularında Demir, Bakır, Çinko ve Magnezyum Konsantrasyonlarının Tayini

Year 1991, Volume: 44 Issue: 4, 529 - 536, 31.12.1991

Orhan Canbolat

Abstract

In this study iron, copper, zinc and magnesium concentrations in cancerous and noncancerous tissues of mammary gland and stomach were determined and results were statistically compared. Statistically meaningful differences were not found between cancerous and noncancerous stomach tissues. However, copper and iron
concentrations in cancerous mammary gland tissues were found higher than noncancerous ones. Similarly, ratios of elements in cancerous mammary gland tissues were found to be changed and relations between elements were found disturbed.

Keywords

KANSER DNA RNA polimeraz

Ethical Statement

-

Supporting Institution

-

Project Number

-

Thanks

-

References

  • 1. Abdulla M Biorklund A Mathur A and Wallerius K : The Role of Zinc in Experimental and Human Oral Cancer. 1978 University of Lund Press, Sweden, Page : 111-114.
  • 2. Breiter DN Diasio RB Niefeld JP Roush ML and Rosenberg SA : Serum copper and zinc measurements in patients with osteogenic carcinoma, Cancer 42 : 598-602; 1978.
  • 3. Hargovcic M Tessmer CF Thomas FB Fuller 1M Gamble JF and Schullenberger CC : Significance of serum copper levels in adult patients with Hodgkin’s Disease. Cancer 31 : 1337-1345; 1973.
  • 4. Heck JD and Costa M: Influence of surface charge and dissolution on the selective phagocytosis of potentially carcinogenic particulate metal compounds. Cancer Res 43 : 5652-5656; 1983.
  • 5. Hsi -A Johnson NP San-Sebastian J O'Neill JP Rahn RO and Forbes NL : Quantitative mammalian cell mutagenesis and a study of mutagenic potential of metallic compounds. In : Trace Metals in Health and Disease. 1979 Raven Press, N.Y. page : 55-69.
  • 6. Issel F Macfadyen BV Gum ET Valdivieso M Dudrick SJ and Bodey GF : Serum zinc levels in lung cancer patients. Cancer 47 : 18451848; 1981.
  • 7. Janes JM McCall JT and Elveback LR : Trace metals in human osteogenic carcinoma, Mayo Clin Proc. 47 : 476-478; 1972.
  • 8. deJorge FB Paiva L Moin D and Da Nova R : Biochemical studies on copper, copper oxidase, magnesium, sulfur, calcium and phosphorus in cancer of the larynx. Acta Otolaryngol 61 : 454-458; 1966.
  • 9. Karcioglu Z Karcioglu G Sarper RM and Hargovcic M : Zinc and copper in neoplastic diseases. In : Zinc and Copper in Medicine. Karcioglu, Z. and Sarper , R.M [eds]1980 Charles C. Thomas Inc., Springfield page : 464-534.
  • 10. Kirkbright GF : Atomic absorption spectroscopy in elemental analysis of biological materials. International Atomic Energy Agency, Technical Report Series, No. 197 : 141-145; 1980.
  • 11. Mulay IL Roy R Knox BE Suhr NH and Delaney WE : Trace metal analysis of cancerous and non-cancerous human tissue, J Natl Cancer Inst 47; 1-18; 1971.
  • 12. . Price WJ : Analytical Atomic Absorption Spectroscopy. 1974 Heiden and Son Ltd., London. Page : 42-44.
  • 13. Rizk SL and Sky-Peck HH : Comparison between concentrations of trace elements in normal and neoplastic human breast tissue. Cancer Res 44 : 5490- 5394; 1984.
  • 14. Santaliquido PM and Southwick HW : Trace metal levels in cancer of the, breast. Surg Gynecol Obstetr 142 ; 65-70; 1976.
  • 15. Schroder HA Nason AP Tipton IH and Balasa JJ : Essential trace metals in man : Zinc. J Chronic Dis 20: 179-186; 1967.
  • 16. Schrauzer GN : The role of trace elements in the etioldgy of cancer. In : Trace Element Analytical Chemistry in Medicine and Biology. 1980 de Gruyter, N.Y. page : 183-198. 17. Scwartz MK : Role of trace elements in cancer. Cancer Res 35 : 3481 3487, 1987.
  • 15. Sigel H led.) : Metal Ions in Biological Systems : Carcinogenicity and Metal Tons, 1980 Marcel Dekker Inc. N.Y. Vol. 10. Page : 132-148.
  • 16. Schrauzer GN : The role of trace elements in the etioldgy of cancer. In : Trace Element Analytical Chemistry in Medicine and Biology. 1980 de Gruyter, N.Y. page : 183-198.
  • 17. Scwartz MK : Role of trace elements in cancer. Cancer Res 35 : 3481 3487, 1987.
  • 18. Sigel H led.) : Metal Ions in Biological Systems : Carcinogenicity and Metal Tons, 1980 Marcel Dekker Inc. N.Y. Vol. 10. Page : 132-148.
  • 19. Sirover MA and Loeb LA : On the fidelity of DNA replication. Effect of metal activators during synthesis with avian myeloblastosis virus DNA polymerase. Biol Chem 252 : 3606-3610, 1977.
  • 20. Sky-Peck HH : Trace metals and neoplasia. Clin Physiol Biochem 4 : 111, 1986.
  • 21. Sunderman FW : Carcinogenic effects of metals. Fed Proc 37 : 40-46, 1979.
  • 22.Sunderman FW : Recent advances in metal carcinogenesis. Ann Clin Lab Sci 14 : 93-122, 1984,
  • 23. Sunderman FW ; Mechanisms of metal carcinogenesis, Biol Trace Element Kes 1: 64-86, 1979.
  • 24. Sunderman FW : Mechanism of metal carcinogenesis. In : The Clinical Bioc- hemistry of Carcinogenesis 1980 American Association of Clinical Chemists, Washington page : 265-297.
  • 25. Tani P and Kokkola K : Serum iron, copper and iron-binding capacity in bronchogenic pulmonary carcinoma, Scand J Hespirat Disease 80 : 121-128, 1972.
  • 26. Valcovic V : Analysis of Biological Material for Trace Elements Using X-Ray Spectroscopy. 1980 CRC Press Inc. Boca Raton. Page : 125-143.
  • 27. Vallee BL and Goldes A : The metallobiochemistry of zinc enzymes. Adv Enz 56 : 283-431, 1984.
  • 28. Weinstein IB : Current concepts in mechanisms of clinical carcinogenesis. Bull N.Y. Acad Med 54 : 366-383, 1978
There are 30 citations in total.

Details

Primary Language Turkish
Subjects Cancer Cell Biology
Journal Section Articles
Authors

Orhan Canbolat

Project Number -
Publication Date December 31, 1991
Published in Issue Year 1991 Volume: 44 Issue: 4

Cite

APA Canbolat, O. (1991). Kanserli Mide ve Meme Dokularında Demir, Bakır, Çinko ve Magnezyum Konsantrasyonlarının Tayini. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 44(4), 529-536.
AMA Canbolat O. Kanserli Mide ve Meme Dokularında Demir, Bakır, Çinko ve Magnezyum Konsantrasyonlarının Tayini. Ankara Üniversitesi Tıp Fakültesi Mecmuası. December 1991;44(4):529-536.
Chicago Canbolat, Orhan. “Kanserli Mide Ve Meme Dokularında Demir, Bakır, Çinko Ve Magnezyum Konsantrasyonlarının Tayini”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 44, no. 4 (December 1991): 529-36.
EndNote Canbolat O (December 1, 1991) Kanserli Mide ve Meme Dokularında Demir, Bakır, Çinko ve Magnezyum Konsantrasyonlarının Tayini. Ankara Üniversitesi Tıp Fakültesi Mecmuası 44 4 529–536.
IEEE O. Canbolat, “Kanserli Mide ve Meme Dokularında Demir, Bakır, Çinko ve Magnezyum Konsantrasyonlarının Tayini”, Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 44, no. 4, pp. 529–536, 1991.
ISNAD Canbolat, Orhan. “Kanserli Mide Ve Meme Dokularında Demir, Bakır, Çinko Ve Magnezyum Konsantrasyonlarının Tayini”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 44/4 (December 1991), 529-536.
JAMA Canbolat O. Kanserli Mide ve Meme Dokularında Demir, Bakır, Çinko ve Magnezyum Konsantrasyonlarının Tayini. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1991;44:529–536.
MLA Canbolat, Orhan. “Kanserli Mide Ve Meme Dokularında Demir, Bakır, Çinko Ve Magnezyum Konsantrasyonlarının Tayini”. Ankara Üniversitesi Tıp Fakültesi Mecmuası, vol. 44, no. 4, 1991, pp. 529-36.
Vancouver Canbolat O. Kanserli Mide ve Meme Dokularında Demir, Bakır, Çinko ve Magnezyum Konsantrasyonlarının Tayini. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 1991;44(4):529-36.
 Download Cover Image