Abstract
Bu çalışmada, termal kağıtlardaki bisfenol A’nın (BPA) kantitatif olarak saptanması için kesin ve hassas bir yöntem geliştirilmiştir. BPA termal kağıtlardan asetonitril-su karışımı ile ekstrakte edilmiştir. BPA’nın ektraksiyon verimi üzerine organik çözücü konsantrasyonunun, ekstraksiyon sıcaklığı ve süresinin, pH’ın etkileri incelenmiştir. Optimize edilen koşullar altında (asetonitril:su oranı 40:60, pH=7, 60 ºC’de, 8 saat), geliştirilen metot beş farklı tipteki termal kağıttan (kasa fişi, POS cihazı fişi, hastane barkodu, ATM fişi, uçak bileti) BPA’nın ekstrakte edilmesi amacıyla uygulanmış ve BPA konsantrasyonları 8.91–10.27 mg g-1 aralığında saptanmıştır. Ayrıca, 5 ve 10 mg g-1 BPA seviyelerindeki spike örnekler için % RSD değerleri sırasıyla 1.80 ve 2.90 olarak belirlenmiştir.
Keywords
References
- Er, B. ve Sarımehmetoğlu, B., Gıdalarda bisfenol A varlığının değerlendirilmesi, Veteriner Hekim Derneği Dergisi, 82, 1, 69-74, (2011).
- Kang, J.H., Kondo, F. ve Katayama, Y., Human exposure to bisphenol A, Toxicology, 226, 79-89, (2006).
- Singh, S. ve Li, S.S.L., Epigenetic effects of environmental chemicals bisphenol A and phthalates, International Journal of Molecular Sciences, 13, 10143-10153, (2012).
- Wolstenholme, J.T., Rissman, E.F. ve Connelly, J.J., The role of bisphenol A in shaping the brain, epigenome and behavior, Hormones and Behavior, 59, 296-305, (2011).
- Mendum, T., Stoler, E., VanBenschoten, H. ve Warner, J.C., Concentration of bisphenol A in thermal paper, Green Chemistry Letters and Reviews, 4, 1, 81-86, (2011).
- Liao, C. ve Kannan, K., Widespread occurrence of bisphenol A in paper and paper products: Implications for human exposure, Environmental Science and Technology, 45, 9372-9379, (2011).
- Zalko, D., Jacques, C., Duplan, H., Bruel, S. ve Perdu, E., Viable skin efficiently absorbs and metabolizes bisphenol A, Chemosphere, 82, 424-430, (2011).
- Biedermann, S., Tschudin, P. ve Grob, K., Transfer of bisphenol A from thermal printer paper to the skin, Analytical and Bioanalytical Chemistry, 398, 571-576, (2010).
- Hormann, A.M., Saal, F.S., Nagel, S.C., Stahlhut, R.W., Moyer, C.L. ve Ellersieck, M.R., Holding thermal receipt paper and eating food after using hand sanitizer results in high serum bioactive and urine total levels of bisphenol A (BPA), Plos One, 9, 10, 1-12, (2014).
Abstract
In this study, a sensitive and accurate method for the quantitative determination of bisphenol A (BPA) in thermal printing paper was developed and validated. BPA was extracted from the thermal printing papers using acetonitrile- water. The effects of organic solvent concentration, extraction temperature and time, pH were investigated. Under the optimized conditions (acetonitrile:water 40:60, v/v, pH=7, 60 ºC, 8 hours), the proposed method was applied to the determination of BPA in five types of thermal printing papers (receipt, POS receipt, hospital barcode, ATM receipt, flight ticket), and the concentration of BPA was found in the range of 8.91-10.27 mg g-1. Furthermore, spiked RSD % of BPA at 5 and 10 mg g-1was found to be 1.80 and 2.90, respectively.
References
- Er, B. ve Sarımehmetoğlu, B., Gıdalarda bisfenol A varlığının değerlendirilmesi, Veteriner Hekim Derneği Dergisi, 82, 1, 69-74, (2011).
- Kang, J.H., Kondo, F. ve Katayama, Y., Human exposure to bisphenol A, Toxicology, 226, 79-89, (2006).
- Singh, S. ve Li, S.S.L., Epigenetic effects of environmental chemicals bisphenol A and phthalates, International Journal of Molecular Sciences, 13, 10143-10153, (2012).
- Wolstenholme, J.T., Rissman, E.F. ve Connelly, J.J., The role of bisphenol A in shaping the brain, epigenome and behavior, Hormones and Behavior, 59, 296-305, (2011).
- Mendum, T., Stoler, E., VanBenschoten, H. ve Warner, J.C., Concentration of bisphenol A in thermal paper, Green Chemistry Letters and Reviews, 4, 1, 81-86, (2011).
- Liao, C. ve Kannan, K., Widespread occurrence of bisphenol A in paper and paper products: Implications for human exposure, Environmental Science and Technology, 45, 9372-9379, (2011).
- Zalko, D., Jacques, C., Duplan, H., Bruel, S. ve Perdu, E., Viable skin efficiently absorbs and metabolizes bisphenol A, Chemosphere, 82, 424-430, (2011).
- Biedermann, S., Tschudin, P. ve Grob, K., Transfer of bisphenol A from thermal printer paper to the skin, Analytical and Bioanalytical Chemistry, 398, 571-576, (2010).
- Hormann, A.M., Saal, F.S., Nagel, S.C., Stahlhut, R.W., Moyer, C.L. ve Ellersieck, M.R., Holding thermal receipt paper and eating food after using hand sanitizer results in high serum bioactive and urine total levels of bisphenol A (BPA), Plos One, 9, 10, 1-12, (2014).
Details
| Primary Language | Turkish |
|---|---|
| Journal Section | Research Articles |
| Authors | |
| Publication Date | March 15, 2019 |
| Submission Date | August 17, 2018 |
| Published in Issue | Year 2019 Volume: 21 Issue: 1 |