Research Article
Year 2025,
, 362 - 369, 30.06.2025
Abstract
Purpose: This study was conducted to examine sensory processing and neuromotor performance in adults with migraine.
Materials and Methods: The study was designed to be observational and comparative. Fifty individuals with migraine and fifty healthy individuals, aged between 18-65, participated in the study. The Adult Sensory Profile Questionnaire was utilized to assess sensory processing skills of individuals and the Clinical Observation of Neuromotor Performance was employed for evaluating neuromotor performance of individuals.
Results: Individuals with migraine demonstrated a distinct sensory processing profile, with significant differences in low registration, sensory sensitivity, and sensory avoidance, but not in sensory seeking. Regarding neuromotor performance, significant differences were observed in postural control, somatodyspraxia including supine flexion and finger tapping and visually guided eye movements, specifically during line tracing, convergence-divergence, and quick localization tasks. No significant differences were found in other neuromotor parameters. These findings highlight selective disruptions in sensorimotor functioning among individuals with migraine.
Conclusion: Given the observed sensory processing difficulties and neuromotor performance challenges in individuals with migraine, further research into neuromotor functioning is warranted. Such studies would not only strengthen the current findings but also offer valuable insights for developing effective intervention protocols to address these issues.
Keywords
References
- Ashina M, Terwindt GM, Al-Karagholi MA, de Boer I, Lee MJ, Hay DL et al. Migraine: disease characterisation, biomarkers, and precision medicine. Lancet. 2021;397:1496-504.
- Headache Classification Committee of the International Headache Society (IHS). The international classification of headache disorders, 3rd edition. Cephalalgia. 2018;38:1-211.
- Brennan KC, Pietrobon D. A systems neuroscience approach to migraine Neuron. 2018;97:1004-21.
- Dai W, Qiu E, Lin X, Liu R, Zhou G, Feng Y et al. Abnormal thalamo-cortical interactions in overlapping communities of migraine: an edge functional connectivity study. Ann Neurol. 2023;94:1168-81.
- Ayres AJ. Sensory Integration and Learning Disorders. Los Angeles, Western Psychological Services. 1972.
- Chien CW, Rodger S, Copley J, Branjerdporn G, Taggart C. Sensory processing and its relationship with children's daily life participation. Phys Occup Ther Pediatr. 2016;36:73-87.
- O'Hare L, Hibbard PB. Visual processing in migraine. Cephalalgia. 2016;36:1057-76.
- Luedtke K, Schulte LH, May A. Visual processing in migraineurs depends on the migraine cycle. Ann Neurol. 2019;85:280-3.
- d’Onofrio F, Barbanti P, Petretta V, Casucci G, Mazzeo A, Bussone G. Migraine and movement disorders. Neurol Sci. 2012;33:S55-9.
- Esposito M, Verrotti A, Gimigliano F, Ruberto M, Agostinelli S, Scuccimarra G et al. Motor coordination impairment and migraine in children: a new comorbidity? Eur J Pediatr. 2012;171:1599-604.
- Carvalho GF, Luedtke K, Pinheiro CF, Jeronymo JC, Bevilaqua-Grossi D. Migraine and balance impairment: influence of subdiagnosis, otoneurological function, falls, and psychosocial factors. Headache. 2022;62:548-57.
- Balıkçı A, Kırteke F, Dirgen GÇ, Özkan A, Öztürk Y, Gökçay G. Dikkat eksikliği ve hiperaktivite bozukluğu tanılı bir vakada Ayres duyu bütünleme temelli ergoterapi müdahalesinin etkileri. Fenerbahçe Ünivsersitesi Sağlık Bilimleri Dergisi. 2021;1:152-67.
- Thompson A, Murphy D, Dell’Acqua F, Ecker C, McAlonan G, Howells H et al. Impaired communication between the motor and somatosensory homunculus is associated with poor manual dexterity in autism spectrum disorder. Biol Psychiatry. 2017;81:211-9.
- Messina R, Rocca MA, Colombo B, Teggi R, Falini A, Comi G et al. Dysregulation of multisensory processing stands out from an early stage of migraine: a study in pediatric patients. J Neurol. 2020;267:760-9.
- Boran HE, Bolay H, Gantenbein AR, Sandor PS, Jancke L, Meyer M. Sensory processing and sensorimotor integration in migraine. In: Neurophysiology of the Migraine Brain. Cham, Springer, 2021;113-31.
- Carvalho GF, Luedtke K, Pinheiro CF, Jeronymo JC, Bevilaqua-Grossi D. Migraine with aura is related to delayed motor control reaction and imbalance following external perturbations. Front Neurol. 2021;12:755990.
- Brown C, Tollefson N, Dunn W, Cromwell R, Filion D. The adult sensory profile: measuring patterns of sensory processing. Am J Occup Ther. 2001;55:75-82.
- Üçgül MŞ, Karahan S, Öksüz Ç. Reliability and validity study of Turkish version of Adolescent/Adult Sensory Profile. Br J Occup Ther. 2017;80:510-6.
- Lane SJ. Sensory modulation. In: Sensory Integration: Theory And Practice (Eds AC Bundy, SJ Lane, EA Murray) 2nd Ed. Philadelphia, F.A. Davis. 2002.
- Cohen J. Statistical Power Analysis for the Behavioral Sciences. 2nd ed. New York, Routledge. 2013.
- Genizi J, Halevy A, Schertz M, Zelnik N, Srugo I. Sensory processing difficulties correlate with disease severity and quality of life among children with migraine. Front Neurol. 2019;10:448.
- Goadsby PJ, Holland PR, Martins-Oliveira M, Hoffmann J, Schankin C, Akerman S. Pathophysiology of migraine: a disorder of sensory processing. Physiol Rev. 2017;97:553-622.
- Meylakh N, Henderson LA. Exploring alterations in sensory pathways in migraine. J Headache Pain. 2022; 23:5.
- Aydın MŞ. Adolesan/yetişkin duyu profili anketi Türkçe uyarlamasının geçerlilik güvenilirlik çalışması [master's thesis]. Ankara: Hacettepe University. 2015.
- Dunn W, Brown C. Factor analysis on the Sensory Profile from a national sample of children without disabilities. Am J Occup Ther. 1997;51:490-5.
- Metz AE, Boling D, DeVore A, Hollenbeck AR. Dunn’s model of sensory processing: an investigation of the axes of the four-quadrant model in healthy adults. Brain Sci. 2019;9:35.
- Neverdahl JP, Uglem M, Matre D, Omland PM, Tronvik E, Sand T. Pain thresholds and suprathreshold pain after sleep restriction in migraine–a blinded crossover study. Cephalalgia. 2022;42:466-80.
- Lévêque Y, Masson R, Fornoni L, Donnet A, Brissart H, Cortese S et al. Self-perceived attention difficulties are associated with sensory hypersensitivity in migraine. Rev Neurol (Paris). 2020;176:829-38.
- Lisicki M, D'Ostilio K, Coppola G, Scholtes F, Maertens de Noordhout A, Parisi V et al. Headache-related alterations of visual processing in migraine patients. J Pain. 2020;.21:593-602.
- Vilà-Balló A, Marti-Marca A, Torres-Ferrús M, Gallardo VJ, Alpuente A, Pozo-Rosich P. Neurophysiological correlates of abnormal auditory processing in episodic migraine during the interictal period. Cephalalgia. 2021;41:45-57.
- Gil-Gouveia R, Martins IP. Clinical description of attack-related cognitive symptoms in migraine: a systematic review. Cephalalgia. 2018;38:1335-50.
- Martins IP. Cognitive performance in chronic migraine. Arq Neuropsiquiatr. 2020;78:131-2.
- Dijkstra BW, Bekkers EM, Gilat M, de Rond V, Hardwick RM, Nieuwboer A. Functional neuroimaging of human postural control: a systematic review with meta-analysis. Neurosci Biobehav Rev. 2020;115:351-62.
- Jürgens TP, Schulte LH, May A. Migraine trait symptoms in migraine with and without aura. Neurology. 2014;82:1416-24.
- Hanson LL, Ahmed Z, Katz BJ, Warner JE, Crum AV, Zhang Y et al. Patients with migraine have substantial reductions in measures of visual quality of life. Headache. 2018;58:1007-13.
- Cui W, Zhang J, Xu F, Wang L, Wang X, Liu F et al. MRI evaluation of the relationship between abnormalities in vision-related brain networks and quality of life in patients with migraine without aura. Neuropsychiatr Dis Treat. 2021;17:3569-79.
- Shepherd AJ, Joly-Mascheroni RM. Visual motion processing in migraine: enhanced motion after-effects are related to display contrast, visual symptoms, visual triggers and attack frequency. Cephalalgia. 2017;37:315-26.
Year 2025,
, 362 - 369, 30.06.2025
Abstract
Amaç: Bu çalışma, migrenli yetişkinlerde duyusal işlemleme ve nöromotor performansı incelemek amacıyla gerçekleştirilmiştir.
Gereç ve Yöntem: Çalışma, gözlemsel ve karşılaştırmalı olarak tasarlanmıştır. 18-65 yaş arasında, migrenli 50 birey ve 50 sağlıklı birey çalışmaya katılmıştır. Bireylerin duyusal işlemleme becerilerini değerlendirmek için Yetişkin Duyusal Profil Anketi kullanılmış, nöromotor performansı değerlendirmek için ise Klinik Nöromotor Performans Gözlemi uygulanmıştır.
Bulgular: Migrenli bireyler, düşük kayıt, duyusal hassasiyet ve duyusal kaçınmada belirgin farklılıklar gösteren, ancak duyusal arayışta fark bulunmayan, kendine özgü bir duyusal işlemleme profili sergilemiştir. Nöromotor performans açısından, postural kontrol, somatotipraksi (sırtüstü fleksiyon ve parmak vurma dahil) ve görsel olarak yönlendirilen göz hareketlerinde, özellikle çizgi izleme, konverjans-diverjans ve hızlı lokalizasyon görevlerinde anlamlı farklılıklar gözlenmiştir. Diğer nöromotor parametrelerde anlamlı bir fark bulunmamıştır. Bu bulgular, migrenli bireylerde seçici sensörimotor işlev bozukluklarını vurgulamaktadır.
Sonuç: Migrenli bireylerde gözlenen duyusal işlemleme güçlükleri ve nöromotor performans zorlukları dikkate alındığında, nöromotor işlevsellik üzerine daha fazla araştırma yapılması gerekmektedir. Bu tür çalışmalar, mevcut bulguları güçlendirmenin yanı sıra, bu sorunları ele almak için etkili müdahale protokolleri geliştirmek adına değerli bilgiler sunacaktır
Keywords
References
- Ashina M, Terwindt GM, Al-Karagholi MA, de Boer I, Lee MJ, Hay DL et al. Migraine: disease characterisation, biomarkers, and precision medicine. Lancet. 2021;397:1496-504.
- Headache Classification Committee of the International Headache Society (IHS). The international classification of headache disorders, 3rd edition. Cephalalgia. 2018;38:1-211.
- Brennan KC, Pietrobon D. A systems neuroscience approach to migraine Neuron. 2018;97:1004-21.
- Dai W, Qiu E, Lin X, Liu R, Zhou G, Feng Y et al. Abnormal thalamo-cortical interactions in overlapping communities of migraine: an edge functional connectivity study. Ann Neurol. 2023;94:1168-81.
- Ayres AJ. Sensory Integration and Learning Disorders. Los Angeles, Western Psychological Services. 1972.
- Chien CW, Rodger S, Copley J, Branjerdporn G, Taggart C. Sensory processing and its relationship with children's daily life participation. Phys Occup Ther Pediatr. 2016;36:73-87.
- O'Hare L, Hibbard PB. Visual processing in migraine. Cephalalgia. 2016;36:1057-76.
- Luedtke K, Schulte LH, May A. Visual processing in migraineurs depends on the migraine cycle. Ann Neurol. 2019;85:280-3.
- d’Onofrio F, Barbanti P, Petretta V, Casucci G, Mazzeo A, Bussone G. Migraine and movement disorders. Neurol Sci. 2012;33:S55-9.
- Esposito M, Verrotti A, Gimigliano F, Ruberto M, Agostinelli S, Scuccimarra G et al. Motor coordination impairment and migraine in children: a new comorbidity? Eur J Pediatr. 2012;171:1599-604.
- Carvalho GF, Luedtke K, Pinheiro CF, Jeronymo JC, Bevilaqua-Grossi D. Migraine and balance impairment: influence of subdiagnosis, otoneurological function, falls, and psychosocial factors. Headache. 2022;62:548-57.
- Balıkçı A, Kırteke F, Dirgen GÇ, Özkan A, Öztürk Y, Gökçay G. Dikkat eksikliği ve hiperaktivite bozukluğu tanılı bir vakada Ayres duyu bütünleme temelli ergoterapi müdahalesinin etkileri. Fenerbahçe Ünivsersitesi Sağlık Bilimleri Dergisi. 2021;1:152-67.
- Thompson A, Murphy D, Dell’Acqua F, Ecker C, McAlonan G, Howells H et al. Impaired communication between the motor and somatosensory homunculus is associated with poor manual dexterity in autism spectrum disorder. Biol Psychiatry. 2017;81:211-9.
- Messina R, Rocca MA, Colombo B, Teggi R, Falini A, Comi G et al. Dysregulation of multisensory processing stands out from an early stage of migraine: a study in pediatric patients. J Neurol. 2020;267:760-9.
- Boran HE, Bolay H, Gantenbein AR, Sandor PS, Jancke L, Meyer M. Sensory processing and sensorimotor integration in migraine. In: Neurophysiology of the Migraine Brain. Cham, Springer, 2021;113-31.
- Carvalho GF, Luedtke K, Pinheiro CF, Jeronymo JC, Bevilaqua-Grossi D. Migraine with aura is related to delayed motor control reaction and imbalance following external perturbations. Front Neurol. 2021;12:755990.
- Brown C, Tollefson N, Dunn W, Cromwell R, Filion D. The adult sensory profile: measuring patterns of sensory processing. Am J Occup Ther. 2001;55:75-82.
- Üçgül MŞ, Karahan S, Öksüz Ç. Reliability and validity study of Turkish version of Adolescent/Adult Sensory Profile. Br J Occup Ther. 2017;80:510-6.
- Lane SJ. Sensory modulation. In: Sensory Integration: Theory And Practice (Eds AC Bundy, SJ Lane, EA Murray) 2nd Ed. Philadelphia, F.A. Davis. 2002.
- Cohen J. Statistical Power Analysis for the Behavioral Sciences. 2nd ed. New York, Routledge. 2013.
- Genizi J, Halevy A, Schertz M, Zelnik N, Srugo I. Sensory processing difficulties correlate with disease severity and quality of life among children with migraine. Front Neurol. 2019;10:448.
- Goadsby PJ, Holland PR, Martins-Oliveira M, Hoffmann J, Schankin C, Akerman S. Pathophysiology of migraine: a disorder of sensory processing. Physiol Rev. 2017;97:553-622.
- Meylakh N, Henderson LA. Exploring alterations in sensory pathways in migraine. J Headache Pain. 2022; 23:5.
- Aydın MŞ. Adolesan/yetişkin duyu profili anketi Türkçe uyarlamasının geçerlilik güvenilirlik çalışması [master's thesis]. Ankara: Hacettepe University. 2015.
- Dunn W, Brown C. Factor analysis on the Sensory Profile from a national sample of children without disabilities. Am J Occup Ther. 1997;51:490-5.
- Metz AE, Boling D, DeVore A, Hollenbeck AR. Dunn’s model of sensory processing: an investigation of the axes of the four-quadrant model in healthy adults. Brain Sci. 2019;9:35.
- Neverdahl JP, Uglem M, Matre D, Omland PM, Tronvik E, Sand T. Pain thresholds and suprathreshold pain after sleep restriction in migraine–a blinded crossover study. Cephalalgia. 2022;42:466-80.
- Lévêque Y, Masson R, Fornoni L, Donnet A, Brissart H, Cortese S et al. Self-perceived attention difficulties are associated with sensory hypersensitivity in migraine. Rev Neurol (Paris). 2020;176:829-38.
- Lisicki M, D'Ostilio K, Coppola G, Scholtes F, Maertens de Noordhout A, Parisi V et al. Headache-related alterations of visual processing in migraine patients. J Pain. 2020;.21:593-602.
- Vilà-Balló A, Marti-Marca A, Torres-Ferrús M, Gallardo VJ, Alpuente A, Pozo-Rosich P. Neurophysiological correlates of abnormal auditory processing in episodic migraine during the interictal period. Cephalalgia. 2021;41:45-57.
- Gil-Gouveia R, Martins IP. Clinical description of attack-related cognitive symptoms in migraine: a systematic review. Cephalalgia. 2018;38:1335-50.
- Martins IP. Cognitive performance in chronic migraine. Arq Neuropsiquiatr. 2020;78:131-2.
- Dijkstra BW, Bekkers EM, Gilat M, de Rond V, Hardwick RM, Nieuwboer A. Functional neuroimaging of human postural control: a systematic review with meta-analysis. Neurosci Biobehav Rev. 2020;115:351-62.
- Jürgens TP, Schulte LH, May A. Migraine trait symptoms in migraine with and without aura. Neurology. 2014;82:1416-24.
- Hanson LL, Ahmed Z, Katz BJ, Warner JE, Crum AV, Zhang Y et al. Patients with migraine have substantial reductions in measures of visual quality of life. Headache. 2018;58:1007-13.
- Cui W, Zhang J, Xu F, Wang L, Wang X, Liu F et al. MRI evaluation of the relationship between abnormalities in vision-related brain networks and quality of life in patients with migraine without aura. Neuropsychiatr Dis Treat. 2021;17:3569-79.
- Shepherd AJ, Joly-Mascheroni RM. Visual motion processing in migraine: enhanced motion after-effects are related to display contrast, visual symptoms, visual triggers and attack frequency. Cephalalgia. 2017;37:315-26.
There are 37 citations in total.
Details
| Primary Language | English |
|---|---|
| Subjects | Neurology and Neuromuscular Diseases |
| Journal Section | Research |
| Authors | |
| Publication Date | June 30, 2025 |
| Submission Date | June 30, 2024 |
| Acceptance Date | May 23, 2025 |
| Published in Issue | Year 2025 |
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