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Year 2025, Volume: 52 Issue: 2, 235 - 244, 20.06.2025

Seda Kumbasar

https://doi.org/10.5798/dicletip.1722859

Abstract

References

  • 1.Disaster and Emergency Management Presidency(2023).06 February 2023 Pazarcık (Kahramanmaraş) Mw7.7 Elbistan (Kahramanmaraş) Mw 7.6 EarthquakesPreliminary Assessment Report (PDF).Access:06.02.2023
  • 2.Zhang L, Zhao M, Fu W, et al. Epidemiological analysisof trauma patients following the Lushan earthquake. PLoSONE. 2014;9.5:e97416.doi: 10.1371/journal.pone.0097416.
  • 3.Mulvey J, Awan S, Qadri A, Maqsood M. Profile ofinjuries arising from the 2005 Kashmir earthquake: thefirst 72 h. Injury. 2008; 39: 554–60.doi: 10.1016/j.injury.2007.07.025.
  • 4.Bartels SA, VanRooyen MJ. Medical complicationsassociated with earthquakes. Lancet. 2012; 379: 748–57.doi: 10.1016/S0140-6736(11)60887-8.
  • 5.Uz I, Çetin M, Songur Kodik M,et al. Emergencydepartment management after the 2020 Aegean Sea -Izmir earthquake. Ulus Travma Acil Cerrahi Derg. 2022;28: 361-8. doi:10.14744/tjtes.2021.89679
  • 6.Yıldırım E, Kaymaz B, Dörtler H, et al. Crush syndrome.FNG & Bilim Tıp Dergisi. 2018; 4(4): 213-8.doi: 10.5606/fng.btd.2018.038
  • 7.Li N, Jiale C, Geng C, et al. Myoglobin promotesmacrophage polarization to M1 type and pyroptosis viathe RIG-I/Caspase1/GSDMD signaling pathway in CS-AKI.Cell Death Discovery, 2022;90. doi: 10.1038/s41420-022-00894-w.
  • 8.Campbell’s operative orthopaedics. S T Canale 9thEdition. Compartment sydromes and VolkmannContracture Jobe M.T. Mosby Co. 1998; 3661-5. 9.Dilektasli E, Inaba K, Haltmeier T, et al. The prognosticvalue of neutrophil-to-lymphocyte ratio on mortality incritically ill trauma patients. J Trauma Acute Care Surg.2016 ; 81(5): 882-8.doi: 10.1097/TA.0000000000000980
  • 10. Templeton AJ, Ace O, McNamara MG, et al. Prognosticrole of platelet to lymphocyte ratio in solid tumors: asystematic review and meta- analysis. Cancer EpidemiolBiomarkers Prev. 2014 ; 23(7): 1204-12.doi:10.1158/1055-9965.EPI-14-0146
  • 11.Cananzi FCM, Ruspi L, Quagliuolo VL. Preoperativemonocyte-to-lymphocyte ratio predicts recurrence ingastrointestinal stromal tumors. J Surg Oncol. 2019;119(1):12-20.
  • 12.Hu B, Yang XR, Xu Y, et al. Systemic immune-inflammation index predicts prognosis of patients aftercurative resection for hepatocellular carcinoma. ClinCancer Res. 2014 ;20(23):6212-22.doi: 10.1002/jso.25290
  • 13.Sever MS, Erek E, Vanholder R, et al. MarmaraEarthquake Study Group. The Marmara earthquake:epidemiological analysis of the victims with nephrologicalproblems. Kidney Int. 2001 ; 60(3): 1114-23. doi:10.1046/j.1523-1755.2001.0600031114
  • 14.Sanchez-Carrillo CI. Morbidity following Mexico City’s1985 earthquakes: clinical and epidemiologic findingsfrom hospitals and emergency units. Pub Health Rep. 198;104: 482-8.
  • 15.Yasar B, Ozbilgehan P, Sen M, Guvendik A. Influenceof systemic inflammatory indices on hospital stay anddialysis post-earthquake: A clinical study. PLOS ONE. 2024;19(2): e0299737.https://doi.org/10.1371/journal.pone.0299737
  • 16.Lee DH, Lee BK, Lee SM, Cho YS, Yun SW. Associationof neutrophil-to-lymphocyte and platelet-to-lymphocyteratios with in-hospital mortality in the early phase ofsevere trauma. Ulus Travma Acil Cerrahi Derg. 2021; 27:290-5. doi: 10.14744/tjtes.2020.02516
  • 17.Sever MS, Erek E, Vanholder R, et al. MarmaraEarthquake Study Group. The Marmara earthquake:admission laboratory features of patients withnephrological problems. Nephrol Dial Transplant. 2002 ;17(6): 1025-31. https://doi.org/10.1093/ndt/17.6.1025
  • 18.Knochel JP. Rhabdomyolysis and acute renal failure.In: Glassock RJ, ed. Current Therapy in Nephrology andHypertension, 4th edn, Mosby, St Louis, 1998; 262–5.doi: 10.1177/039139880402701204
  • 19.Kurultak İ. Crush syndrome in earthquake injuredadult patients. Journal of TOTBİD. 2022; 21: 294-303.
  • 20.Vanholder R, Sükrü Sever M, Lameire N. Kidneyproblems in disaster situations. Nephrol Ther. 2021; 17:27-36. doi: 10.1016/j.nephro.2020.02.009
  • 21.Canbakan B, Yüksel C, Atalay HC, et al. The evaluatıonof Crush syndrome patıents who are observed ın ourhospıtal after the marmara earthquake on 17th august ın1999. T Klin J Med Sci. 2001; 21: 377-80.
  • 22.Sever MŞ, Erek E, Vanholder R, et al. The Marmaraearthquake: admission laboratory features of patientswith nephrological problems, Nephrology DialysisTransplantation. 2002; 17: 1025-31.
  • 23.Shigemoto T, Rinka H, Matsuo Y, et al. Bloodpurification for crush syndrome. Ren Fail. 1997; 19: 711-9.doi: 10.3109/08860229709109037
  • 24.Rizo-Topete L, Ronco C. Critical Care Nephrology: AMultidisciplinary Approach. Blood Purif. 2017; 43(1-3):53-6. doi: 10.1159/000453018
  • 25.Omrani H, Najafi I, Bahrami K, Najafi F, Safari S. Acutekidney injury following traumatic rhabdomyolysis inKermanshah earthquake victims; A cross-sectional study,American Journal of Emergency Medicine. 2021; 40: 127-32.https://doi.org/10.1016/j.ajem.2020.01.043

Relationship between earthquake ınjuries and ınflammatory blood parameters

Year 2025, Volume: 52 Issue: 2, 235 - 244, 20.06.2025

Seda Kumbasar

https://doi.org/10.5798/dicletip.1722859

Abstract

Objective: An earthquake is a significant natural disaster with the potential to cause considerable mortality, economic disruption, and psychological effects. The purpose of this study was to investigate the impact of laboratory parameters on the triage, treatment, and survival of patients with injuries of varying severity who sustained traumatic injuries amid debris.
Methods: This retrospective study included 1250 adult earthquake victims who were received outpatients and inpatient treatment in our hospital between February 6 and February 23, 2023. The patients were classified into three categories. The first group includ ed individuals with soft tissue injuries but no fractures or major injuries. The second group included those with fractures but no major visceral injuries and crush syndrome. The third group included individuals with lung contusion, pneumothorax, intracranial hemorrhage, intra-abdominal hemorrhage, crush syndrome and compartment syndrome.
Results: Alanine transaminase, creatine kinase, myoglobin, D-dimer, white blood cell count, absolute neutrophil count, absolute monocyte count, C- aspartate transaminase reactive protein, neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, monocyte/lymphocyte ratio, and the systemic inflammatory index were progressively higher in all three groups. Absolute-lymphocyte counts and calcium were progressively less different (p<0. 001). Patients in the third group exhibited elevated creatinine levels and diminished blood sodium levels in comparison to the other groups (p<0.001).The mean hemoglobin level was lower in the third group than in the first group, while the mean gamma glutamyl transaminase level was higher(p<0.001).
Discussion: These specific laboratory parameters can be used to identify high-risk patients with crush syndrome and major organ injury. This approach could enable the prioritisation of treatment for those who need it most, ensuring the optimal allocation of resources.

Keywords

Earthquake Crush Injury

References

  • 1.Disaster and Emergency Management Presidency(2023).06 February 2023 Pazarcık (Kahramanmaraş) Mw7.7 Elbistan (Kahramanmaraş) Mw 7.6 EarthquakesPreliminary Assessment Report (PDF).Access:06.02.2023
  • 2.Zhang L, Zhao M, Fu W, et al. Epidemiological analysisof trauma patients following the Lushan earthquake. PLoSONE. 2014;9.5:e97416.doi: 10.1371/journal.pone.0097416.
  • 3.Mulvey J, Awan S, Qadri A, Maqsood M. Profile ofinjuries arising from the 2005 Kashmir earthquake: thefirst 72 h. Injury. 2008; 39: 554–60.doi: 10.1016/j.injury.2007.07.025.
  • 4.Bartels SA, VanRooyen MJ. Medical complicationsassociated with earthquakes. Lancet. 2012; 379: 748–57.doi: 10.1016/S0140-6736(11)60887-8.
  • 5.Uz I, Çetin M, Songur Kodik M,et al. Emergencydepartment management after the 2020 Aegean Sea -Izmir earthquake. Ulus Travma Acil Cerrahi Derg. 2022;28: 361-8. doi:10.14744/tjtes.2021.89679
  • 6.Yıldırım E, Kaymaz B, Dörtler H, et al. Crush syndrome.FNG & Bilim Tıp Dergisi. 2018; 4(4): 213-8.doi: 10.5606/fng.btd.2018.038
  • 7.Li N, Jiale C, Geng C, et al. Myoglobin promotesmacrophage polarization to M1 type and pyroptosis viathe RIG-I/Caspase1/GSDMD signaling pathway in CS-AKI.Cell Death Discovery, 2022;90. doi: 10.1038/s41420-022-00894-w.
  • 8.Campbell’s operative orthopaedics. S T Canale 9thEdition. Compartment sydromes and VolkmannContracture Jobe M.T. Mosby Co. 1998; 3661-5. 9.Dilektasli E, Inaba K, Haltmeier T, et al. The prognosticvalue of neutrophil-to-lymphocyte ratio on mortality incritically ill trauma patients. J Trauma Acute Care Surg.2016 ; 81(5): 882-8.doi: 10.1097/TA.0000000000000980
  • 10. Templeton AJ, Ace O, McNamara MG, et al. Prognosticrole of platelet to lymphocyte ratio in solid tumors: asystematic review and meta- analysis. Cancer EpidemiolBiomarkers Prev. 2014 ; 23(7): 1204-12.doi:10.1158/1055-9965.EPI-14-0146
  • 11.Cananzi FCM, Ruspi L, Quagliuolo VL. Preoperativemonocyte-to-lymphocyte ratio predicts recurrence ingastrointestinal stromal tumors. J Surg Oncol. 2019;119(1):12-20.
  • 12.Hu B, Yang XR, Xu Y, et al. Systemic immune-inflammation index predicts prognosis of patients aftercurative resection for hepatocellular carcinoma. ClinCancer Res. 2014 ;20(23):6212-22.doi: 10.1002/jso.25290
  • 13.Sever MS, Erek E, Vanholder R, et al. MarmaraEarthquake Study Group. The Marmara earthquake:epidemiological analysis of the victims with nephrologicalproblems. Kidney Int. 2001 ; 60(3): 1114-23. doi:10.1046/j.1523-1755.2001.0600031114
  • 14.Sanchez-Carrillo CI. Morbidity following Mexico City’s1985 earthquakes: clinical and epidemiologic findingsfrom hospitals and emergency units. Pub Health Rep. 198;104: 482-8.
  • 15.Yasar B, Ozbilgehan P, Sen M, Guvendik A. Influenceof systemic inflammatory indices on hospital stay anddialysis post-earthquake: A clinical study. PLOS ONE. 2024;19(2): e0299737.https://doi.org/10.1371/journal.pone.0299737
  • 16.Lee DH, Lee BK, Lee SM, Cho YS, Yun SW. Associationof neutrophil-to-lymphocyte and platelet-to-lymphocyteratios with in-hospital mortality in the early phase ofsevere trauma. Ulus Travma Acil Cerrahi Derg. 2021; 27:290-5. doi: 10.14744/tjtes.2020.02516
  • 17.Sever MS, Erek E, Vanholder R, et al. MarmaraEarthquake Study Group. The Marmara earthquake:admission laboratory features of patients withnephrological problems. Nephrol Dial Transplant. 2002 ;17(6): 1025-31. https://doi.org/10.1093/ndt/17.6.1025
  • 18.Knochel JP. Rhabdomyolysis and acute renal failure.In: Glassock RJ, ed. Current Therapy in Nephrology andHypertension, 4th edn, Mosby, St Louis, 1998; 262–5.doi: 10.1177/039139880402701204
  • 19.Kurultak İ. Crush syndrome in earthquake injuredadult patients. Journal of TOTBİD. 2022; 21: 294-303.
  • 20.Vanholder R, Sükrü Sever M, Lameire N. Kidneyproblems in disaster situations. Nephrol Ther. 2021; 17:27-36. doi: 10.1016/j.nephro.2020.02.009
  • 21.Canbakan B, Yüksel C, Atalay HC, et al. The evaluatıonof Crush syndrome patıents who are observed ın ourhospıtal after the marmara earthquake on 17th august ın1999. T Klin J Med Sci. 2001; 21: 377-80.
  • 22.Sever MŞ, Erek E, Vanholder R, et al. The Marmaraearthquake: admission laboratory features of patientswith nephrological problems, Nephrology DialysisTransplantation. 2002; 17: 1025-31.
  • 23.Shigemoto T, Rinka H, Matsuo Y, et al. Bloodpurification for crush syndrome. Ren Fail. 1997; 19: 711-9.doi: 10.3109/08860229709109037
  • 24.Rizo-Topete L, Ronco C. Critical Care Nephrology: AMultidisciplinary Approach. Blood Purif. 2017; 43(1-3):53-6. doi: 10.1159/000453018
  • 25.Omrani H, Najafi I, Bahrami K, Najafi F, Safari S. Acutekidney injury following traumatic rhabdomyolysis inKermanshah earthquake victims; A cross-sectional study,American Journal of Emergency Medicine. 2021; 40: 127-32.https://doi.org/10.1016/j.ajem.2020.01.043
There are 24 citations in total.

Details

Primary Language English
Subjects Medical Education, Health Services and Systems (Other)
Journal Section Original Articles
Authors

Seda Kumbasar

Publication Date June 20, 2025
Submission Date December 30, 2024
Acceptance Date April 11, 2025
Published in Issue Year 2025 Volume: 52 Issue: 2

Cite

APA Kumbasar, S. (2025). Relationship between earthquake ınjuries and ınflammatory blood parameters. Dicle Medical Journal, 52(2), 235-244. https://doi.org/10.5798/dicletip.1722859
AMA Kumbasar S. Relationship between earthquake ınjuries and ınflammatory blood parameters. diclemedj. June 2025;52(2):235-244. doi:10.5798/dicletip.1722859
Chicago Kumbasar, Seda. “Relationship Between Earthquake ınjuries and ınflammatory Blood Parameters”. Dicle Medical Journal 52, no. 2 (June 2025): 235-44. https://doi.org/10.5798/dicletip.1722859.
EndNote Kumbasar S (June 1, 2025) Relationship between earthquake ınjuries and ınflammatory blood parameters. Dicle Medical Journal 52 2 235–244.
IEEE S. Kumbasar, “Relationship between earthquake ınjuries and ınflammatory blood parameters”, diclemedj, vol. 52, no. 2, pp. 235–244, 2025, doi: 10.5798/dicletip.1722859.
ISNAD Kumbasar, Seda. “Relationship Between Earthquake ınjuries and ınflammatory Blood Parameters”. Dicle Medical Journal 52/2 (June 2025), 235-244. https://doi.org/10.5798/dicletip.1722859.
JAMA Kumbasar S. Relationship between earthquake ınjuries and ınflammatory blood parameters. diclemedj. 2025;52:235–244.
MLA Kumbasar, Seda. “Relationship Between Earthquake ınjuries and ınflammatory Blood Parameters”. Dicle Medical Journal, vol. 52, no. 2, 2025, pp. 235-44, doi:10.5798/dicletip.1722859.
Vancouver Kumbasar S. Relationship between earthquake ınjuries and ınflammatory blood parameters. diclemedj. 2025;52(2):235-44.
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