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Year 2014, Volume: 19 Issue: 1, 38 - 40, 29.04.2014

W Hamizan Aneeza , Rajalingham Sakthiswary Suria Hayati Md Pauzi B.s. Gendeh

Abstract

References

  • James PD, Goodeve AC. von Willebrand disease. Genet Medicine 2011; 13: 365-376.
  • Scaramuzzi N, Walsh R, Brennan P, Walsh M. Treatment of intractable epistaxis using arterial embolization. Clin Otolaryngol & Allied Sciences 2008; 26: 307-309.
  • Bakri K, Haydar AA, Davis J, et al. Waldenström's macroglobulinaemia presenting as isolated epistaxis: a common complaint but a rare cause. Int J clin pract 2004; 58: 81-82.
  • Dutta M, Ghatak S, Dutta S, et al. Glanzmann’s Thrombasthenia: A Rare Cause of Recurrent Profuse Epistaxis. Ind J Hemat Blood Transfusion 2011; 27: 113Nichols W, Hultin M, James A, et al. von Willebrand disease (VWD): evidence‐based diagnosis and management guidelines, the National Heart, Lung, and Blood Institute (NHLBI) Expert Panel report (USA) 1. Haemophilia 2008; 14: 171-232.
  • Wood AJJ, Mannucci PM. Treatment of von Willebrand's disease. N Eng J Med 2004; 351: 6836
  • Tefferi A, Nichols WL. Acquired von Willebrand disease: concise review of occurrence, diagnosis, pathogenesis, and treatment. Am J Med 1997; 103: 5
  • Kumar S, Pruthi RK, Nichols WL, Acquired von Willebrand disease. Mayo Clinic Proceedings; 2002: Mayo Foundation.
  • Fukutsuji K, Nishiike S, Aihara T, et al. Superselective angiographic embolization for intractable epistaxis. Acta oto-laryngol (stockh) 2008; 128: 556-560.

Von Willebrand Disease type 2B: A diagnostic dilemma

Year 2014, Volume: 19 Issue: 1, 38 - 40, 29.04.2014

W Hamizan Aneeza , Rajalingham Sakthiswary Suria Hayati Md Pauzi B.s. Gendeh

Abstract

A young female presented with isolated chronic unilateral intractable epistaxis with non healing granular mass in the left nasal cavity.  Histopathological examination was reported as acute and chronic non specific inflammation which did not respond to antibiotics or steroid.  After ten years follow up she was finally diagnosed to have Von Willebrand disease type 2B. This is the first case report of von Willebrand disease presenting with intermittent epistaxis as its sole disease manifestation. Although epistaxis is a common complaint in Otorhinolaryngology clinics, this case posed a diagnostic dilemma.

Keywords

Type 2 von Willebrand Disease epistaxis isolated Wegener’s Granulomatosis

References

  • James PD, Goodeve AC. von Willebrand disease. Genet Medicine 2011; 13: 365-376.
  • Scaramuzzi N, Walsh R, Brennan P, Walsh M. Treatment of intractable epistaxis using arterial embolization. Clin Otolaryngol & Allied Sciences 2008; 26: 307-309.
  • Bakri K, Haydar AA, Davis J, et al. Waldenström's macroglobulinaemia presenting as isolated epistaxis: a common complaint but a rare cause. Int J clin pract 2004; 58: 81-82.
  • Dutta M, Ghatak S, Dutta S, et al. Glanzmann’s Thrombasthenia: A Rare Cause of Recurrent Profuse Epistaxis. Ind J Hemat Blood Transfusion 2011; 27: 113Nichols W, Hultin M, James A, et al. von Willebrand disease (VWD): evidence‐based diagnosis and management guidelines, the National Heart, Lung, and Blood Institute (NHLBI) Expert Panel report (USA) 1. Haemophilia 2008; 14: 171-232.
  • Wood AJJ, Mannucci PM. Treatment of von Willebrand's disease. N Eng J Med 2004; 351: 6836
  • Tefferi A, Nichols WL. Acquired von Willebrand disease: concise review of occurrence, diagnosis, pathogenesis, and treatment. Am J Med 1997; 103: 5
  • Kumar S, Pruthi RK, Nichols WL, Acquired von Willebrand disease. Mayo Clinic Proceedings; 2002: Mayo Foundation.
  • Fukutsuji K, Nishiike S, Aihara T, et al. Superselective angiographic embolization for intractable epistaxis. Acta oto-laryngol (stockh) 2008; 128: 556-560.
There are 8 citations in total.

Details

Primary Language English
Journal Section Case Report
Authors

W Hamizan Aneeza

Rajalingham Sakthiswary

Suria Hayati Md Pauzi

B.s. Gendeh

Publication Date April 29, 2014
Published in Issue Year 2014 Volume: 19 Issue: 1

Cite

APA Aneeza, W. H., Sakthiswary, R., Pauzi, S. H. M., Gendeh, B. (2014). Von Willebrand Disease type 2B: A diagnostic dilemma. EASTERN JOURNAL OF MEDICINE, 19(1), 38-40.
AMA Aneeza WH, Sakthiswary R, Pauzi SHM, Gendeh B. Von Willebrand Disease type 2B: A diagnostic dilemma. EASTERN JOURNAL OF MEDICINE. April 2014;19(1):38-40.
Chicago Aneeza, W Hamizan, Rajalingham Sakthiswary, Suria Hayati Md Pauzi, and B.s. Gendeh. “Von Willebrand Disease Type 2B: A Diagnostic Dilemma”. EASTERN JOURNAL OF MEDICINE 19, no. 1 (April 2014): 38-40.
EndNote Aneeza WH, Sakthiswary R, Pauzi SHM, Gendeh B (April 1, 2014) Von Willebrand Disease type 2B: A diagnostic dilemma. EASTERN JOURNAL OF MEDICINE 19 1 38–40.
IEEE W. H. Aneeza, R. Sakthiswary, S. H. M. Pauzi, and B. Gendeh, “Von Willebrand Disease type 2B: A diagnostic dilemma”, EASTERN JOURNAL OF MEDICINE, vol. 19, no. 1, pp. 38–40, 2014.
ISNAD Aneeza, W Hamizan et al. “Von Willebrand Disease Type 2B: A Diagnostic Dilemma”. EASTERN JOURNAL OF MEDICINE 19/1 (April 2014), 38-40.
JAMA Aneeza WH, Sakthiswary R, Pauzi SHM, Gendeh B. Von Willebrand Disease type 2B: A diagnostic dilemma. EASTERN JOURNAL OF MEDICINE. 2014;19:38–40.
MLA Aneeza, W Hamizan et al. “Von Willebrand Disease Type 2B: A Diagnostic Dilemma”. EASTERN JOURNAL OF MEDICINE, vol. 19, no. 1, 2014, pp. 38-40.
Vancouver Aneeza WH, Sakthiswary R, Pauzi SHM, Gendeh B. Von Willebrand Disease type 2B: A diagnostic dilemma. EASTERN JOURNAL OF MEDICINE. 2014;19(1):38-40.