The effect of swallowing disorder on quality of life in patients with Parkinson’s disease

Dilara Bingöl; Serkan Bengisu; Zeynep Tüfekçioğlu; Ecem Nur Demirsoy; Haşmet Hanağası; Seyhun Topbaş

doi:10.18621/eurj.1600087

Research Article

The effect of swallowing disorder on quality of life in patients with Parkinson’s disease

Year 2025, Volume: 11 Issue: 4, 697 - 704, 04.07.2025

Dilara Bingöl , Serkan Bengisu , Zeynep Tüfekçioğlu , Ecem Nur Demirsoy , Haşmet Hanağası , Seyhun Topbaş

https://doi.org/10.18621/eurj.1600087

Abstract

Objectives: The aim of this study is to evaluate the severity of dysphagia in Idiopathic Parkinson's Disease (IPD) using both self-assessment and clinical assessment tools, to investigate the correlation between these methods, and to examine the effect of dysphagia on quality of life.

Methods: Patients diagnosed with IPD who applied to the Movement Disorders Clinic of the Neurology Department of Istanbul University Faculty of Medicine between 2020-2021 were included in the study. Dysphagia severity was assessed using the Eating Assessment Tool (EAT-10), Dysphagia Disability Index (DHI), and Gugging Swallowing Screening (GUSS). The effect of dysphagia on quality of life was assessed using the Turkish Swallowing Quality of Life Questionnaire (T-SWAL-QOL).

Results: A total of 38 patients, 24 (63.2%) of whom were male, were included in the study. There was a moderate correlation between GUSS and EAT-10 scores (r: -0.548; P<0.01). All areas of the quality of life questionnaire were negatively affected, with the most prominent problems being fatigue, sleep, and communication problems. The questionnaire scores showed a moderate correlation with EAT-10 scores (r: -0.583; P<0.01), a high correlation with DHI scores (r: -0.751; P<0.01)

Conclusions: This study demonstrates that dysphagia in IPD negatively impacts quality of life in several ways. The similar results obtained from self-assessment scales and clinical measures suggest that the clinician may include the results of self-assessment scales when screening for swallowing disorders.

Keywords

Dysphagia, swallowing disorder, Parkinson, quality of life

Ethical Statement

This study was approved by the İstanbul Medipol University Non-Interventional Clinical Research Ethics Committee (Date: 26.10.2021, Decision No: 1060) and informed written consent was obtained from all participants.

References

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4. Han M, Ohnishi H, Nonaka M, et al. Relationship between dysphagia and depressive states in patients with Parkinson's disease. Parkinsonism Relat Disord. 2011;17(6):437-439. doi: 10.1016/j.parkreldis.2011.03.006.
5. Ertekin C, Aydoğdu İ, Seçil Y. [Physiology and neurology of oropharyngeal swallowing]. Ege Tıp Derg. 2002;41(3):163-175. [Article in Turkish]
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7. Leow LP, Huckabee ML, Anderson T, Beckert L. The impact of dysphagia on quality of life in ageing and Parkinson's disease as measured by the swallowing quality of life (SWAL-QOL) questionnaire. Dysphagia. 2010;25(3):216-220. doi: 10.1007/s00455-009-9245-9.
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11. Macit R. Parkinson hastalarında yutma kaygısının anksiyete ve depresyonla olan ilişkisi [Tıpta uzmanlık tezi]. İstanbul: Sağlık Bilimleri Üniversitesi; 2018. Türkçe. (YÖK Tez No: 507984).
12. Coşkun R. Parkinson hastalığında ses ve yutma fonksiyonlarının değerlendirilmesi [Yüksek Lisans Tezi]. Ege Üniversitesi; 2020.
13. Hughes AJ, Daniel SE, Kilford L, Lees AJ. Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases. J Neurol Neurosurg Psychiatry. 1992;55(3):181-184. doi: 10.1136/jnnp.55.3.181.
14. Demir N, Serel Arslan S, İnal Ö, Karaduman AA. Reliability and Validity of the Turkish Eating Assessment Tool (T-EAT-10). Dysphagia. 2016;31(5):644-9. doi: 10.1007/s00455-016-9723-9.
15. Çiyiltepe M, Şenkal ÖA, Sarıyer M, Mutlu F. Development of the Turkish version of the dysphagia handicap index (DHI-T). 5th ESSD Congress; 2015; Barcelona, Spain.
16. Umay EK, Gürçay E, Bahçeci K, et al. Validity and reliability of Turkish version of the Gugging Swallowing Screen test in the early period of hemispheric stroke. Neurol Sci Neurophysiol. 2018;35(1):6-13.
17. Trapl M, Enderle P, Nowotny M, Teuschl Y, Matz K, Dachenhausen A, Brainin M. Dysphagia bedside screening for acute-stroke patients: the Gugging Swallowing Screen. Stroke. 2007;38(11):2948-2952. doi: 10.1161/STROKEAHA.107.483933.
18. Demir N, Serel Arslan S, İnal Ö, Ünlüer NÖ, Karaduman AA, Reliability and Validity of the Turkish Version of the Swallow Quality Of Life Questionnaire. Turk J Physiother Rehabil. 2016; 27(1):19-24. doi: 10.21653/tfrd.217061.
19. Bayram HM. Yutma bozukluğu olan yaşlı bireylerde beslenme durumu ve yaşam kalitesinin değerlendirilmesi [Doctora Tezi]. Hacettepe Üniversitesi; 2016.
20. Yaşaroğlu ÖF. Nörojenik yutma bozukluğu olan hastalarda Yeme Değerlendirme Aracı ve Yutma Yaşam Kalitesi Anketi’nin değerlendirilmesi [yüksek lisans tezi]. Ankara: Hacettepe Üniversitesi, Sağlık Bilimleri Enstitüsü; 2018.
21. Çelik F. Demanslı hastalarda yutma bozukluğunun yaşam kalitesine etkisi [yüksek lisans tezi]. Eskişehir: Anadolu Üniversitesi; 2016.
22. Durmaz MG. İnmeli hastalarda yatak başı yutma tarama testi (GUSS) ile videofloroskopi sonuçlarının karşılaştırılması [yüksek lisans tezi]. İstanbul: İstanbul Üniversitesi-Cerrahpaşa; 2019.
23. Bengisu S, Savaş M, Aygün D, Kahraman Beğen S, Altıntaş T, Manay B. Impact of Parkinson's disease-related dysphagia severity on quality of life: Comparison between self-reports and videofluoroscopic swallowing study results. Tr-ENT. 2024;34(3):84-91. doi: 10.26650/Tr-ENT.2024.1491389.
24. Şahnalı V. Mekanik kökenli yutma güçlüğü olan hastalarda yutma bozukluklarının yaşam kalitesine etkilerinin değerlendirilmesi [Yüksek Lisans Tezi]. Anadolu Üniversitesi; 2017.
25. Chan HF, Ng ML, Kim H, Kim DY. Swallowing-related quality of life among oral-feeding Chinese patients with Parkinson's disease - a preliminary study using Chinese SWAL-QOL. Disabil Rehabil. 2022;44(7):1077-1083. doi: 10.1080/09638288.2020.1791979.
26. Li HJ, Zhang MF, Chen MX, et al. Validation of the nonmotor symptoms questionnaire for Parkinson's disease: results from a Chinese pilot study. Int J Neurosci. 2015;125(12):929-935. doi: 10.3109/00207454.2014.986573.
27. Miller N. Communication changes in Parkinson's disease. Pract Neurol. 2017;17(4):266-274. doi: 10.1136/practneurol-2017-001635.
28. Duffy JR. Motor Speech Disorders E-Book: Motor Speech Disorders E-Book. Elsevier Health Sciences; 2019.

Year 2025, Volume: 11 Issue: 4, 697 - 704, 04.07.2025

Dilara Bingöl , Serkan Bengisu , Zeynep Tüfekçioğlu , Ecem Nur Demirsoy , Haşmet Hanağası , Seyhun Topbaş

https://doi.org/10.18621/eurj.1600087

Abstract

References

1. Poewe W, Seppi K, Tanner CM, et al. Parkinson disease. Nat Rev Dis Primers. 2017;3:17013. doi: 10.1038/nrdp.2017.13.
2. Takizawa C, Gemmell E, Kenworthy J, Speyer R. A Systematic Review of the Prevalence of Oropharyngeal Dysphagia in Stroke, Parkinson's Disease, Alzheimer's Disease, Head Injury, and Pneumonia. Dysphagia. 2016;31(3):434-441. doi: 10.1007/s00455-016-9695-9.
3. Kalf JG, de Swart BJ, Bloem BR, Munneke M. Prevalence of oropharyngeal dysphagia in Parkinson's disease: a meta-analysis. Parkinsonism Relat Disord. 2012;18(4):311-315. doi: 10.1016/j.parkreldis.2011.11.006.
4. Han M, Ohnishi H, Nonaka M, et al. Relationship between dysphagia and depressive states in patients with Parkinson's disease. Parkinsonism Relat Disord. 2011;17(6):437-439. doi: 10.1016/j.parkreldis.2011.03.006.
5. Ertekin C, Aydoğdu İ, Seçil Y. [Physiology and neurology of oropharyngeal swallowing]. Ege Tıp Derg. 2002;41(3):163-175. [Article in Turkish]
6. Martinez-Martin P, Deuschl G, Tonder L, et al. Interpretation of health-related quality of life outcomes in Parkinson's disease from the EARLYSTIM Study. PLoS One. 2020;15(8):e0237498. doi: 10.1371/journal.pone.0237498.
7. Leow LP, Huckabee ML, Anderson T, Beckert L. The impact of dysphagia on quality of life in ageing and Parkinson's disease as measured by the swallowing quality of life (SWAL-QOL) questionnaire. Dysphagia. 2010;25(3):216-220. doi: 10.1007/s00455-009-9245-9.
8. Menezes DCD. Impacto dos distúrbios da deglutição na qualidade de vida de parkinsonianos [master’s thesis]. Recife (PE): Universidade Federal de Pernambuco; 2011.
9. Van Hooren MR, Baijens LW, Vos R, et al. Voice- and swallow-related quality of life in idiopathic Parkinson's disease. Laryngoscope. 2016;126(2):408-414. doi: 10.1002/lary.25481.
10. Plowman-Prine EK, Sapienza CM, Okun MS, et al. The relationship between quality of life and swallowing in Parkinson's disease. Mov Disord. 2009;24(9):1352-1358. doi: 10.1002/mds.22617.
11. Macit R. Parkinson hastalarında yutma kaygısının anksiyete ve depresyonla olan ilişkisi [Tıpta uzmanlık tezi]. İstanbul: Sağlık Bilimleri Üniversitesi; 2018. Türkçe. (YÖK Tez No: 507984).
12. Coşkun R. Parkinson hastalığında ses ve yutma fonksiyonlarının değerlendirilmesi [Yüksek Lisans Tezi]. Ege Üniversitesi; 2020.
13. Hughes AJ, Daniel SE, Kilford L, Lees AJ. Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases. J Neurol Neurosurg Psychiatry. 1992;55(3):181-184. doi: 10.1136/jnnp.55.3.181.
14. Demir N, Serel Arslan S, İnal Ö, Karaduman AA. Reliability and Validity of the Turkish Eating Assessment Tool (T-EAT-10). Dysphagia. 2016;31(5):644-9. doi: 10.1007/s00455-016-9723-9.
15. Çiyiltepe M, Şenkal ÖA, Sarıyer M, Mutlu F. Development of the Turkish version of the dysphagia handicap index (DHI-T). 5th ESSD Congress; 2015; Barcelona, Spain.
16. Umay EK, Gürçay E, Bahçeci K, et al. Validity and reliability of Turkish version of the Gugging Swallowing Screen test in the early period of hemispheric stroke. Neurol Sci Neurophysiol. 2018;35(1):6-13.
17. Trapl M, Enderle P, Nowotny M, Teuschl Y, Matz K, Dachenhausen A, Brainin M. Dysphagia bedside screening for acute-stroke patients: the Gugging Swallowing Screen. Stroke. 2007;38(11):2948-2952. doi: 10.1161/STROKEAHA.107.483933.
18. Demir N, Serel Arslan S, İnal Ö, Ünlüer NÖ, Karaduman AA, Reliability and Validity of the Turkish Version of the Swallow Quality Of Life Questionnaire. Turk J Physiother Rehabil. 2016; 27(1):19-24. doi: 10.21653/tfrd.217061.
19. Bayram HM. Yutma bozukluğu olan yaşlı bireylerde beslenme durumu ve yaşam kalitesinin değerlendirilmesi [Doctora Tezi]. Hacettepe Üniversitesi; 2016.
20. Yaşaroğlu ÖF. Nörojenik yutma bozukluğu olan hastalarda Yeme Değerlendirme Aracı ve Yutma Yaşam Kalitesi Anketi’nin değerlendirilmesi [yüksek lisans tezi]. Ankara: Hacettepe Üniversitesi, Sağlık Bilimleri Enstitüsü; 2018.
21. Çelik F. Demanslı hastalarda yutma bozukluğunun yaşam kalitesine etkisi [yüksek lisans tezi]. Eskişehir: Anadolu Üniversitesi; 2016.
22. Durmaz MG. İnmeli hastalarda yatak başı yutma tarama testi (GUSS) ile videofloroskopi sonuçlarının karşılaştırılması [yüksek lisans tezi]. İstanbul: İstanbul Üniversitesi-Cerrahpaşa; 2019.
23. Bengisu S, Savaş M, Aygün D, Kahraman Beğen S, Altıntaş T, Manay B. Impact of Parkinson's disease-related dysphagia severity on quality of life: Comparison between self-reports and videofluoroscopic swallowing study results. Tr-ENT. 2024;34(3):84-91. doi: 10.26650/Tr-ENT.2024.1491389.
24. Şahnalı V. Mekanik kökenli yutma güçlüğü olan hastalarda yutma bozukluklarının yaşam kalitesine etkilerinin değerlendirilmesi [Yüksek Lisans Tezi]. Anadolu Üniversitesi; 2017.
25. Chan HF, Ng ML, Kim H, Kim DY. Swallowing-related quality of life among oral-feeding Chinese patients with Parkinson's disease - a preliminary study using Chinese SWAL-QOL. Disabil Rehabil. 2022;44(7):1077-1083. doi: 10.1080/09638288.2020.1791979.
26. Li HJ, Zhang MF, Chen MX, et al. Validation of the nonmotor symptoms questionnaire for Parkinson's disease: results from a Chinese pilot study. Int J Neurosci. 2015;125(12):929-935. doi: 10.3109/00207454.2014.986573.
27. Miller N. Communication changes in Parkinson's disease. Pract Neurol. 2017;17(4):266-274. doi: 10.1136/practneurol-2017-001635.
28. Duffy JR. Motor Speech Disorders E-Book: Motor Speech Disorders E-Book. Elsevier Health Sciences; 2019.

There are 28 citations in total.

Details

Primary Language	English
Subjects	Public Health (Other)
Journal Section	Original Articles
Authors	Dilara Bingöl 0000-0001-8440-1212 Serkan Bengisu 0000-0002-6580-1189 Zeynep Tüfekçioğlu 0000-0001-6989-8611 Ecem Nur Demirsoy 0000-0002-2595-1676 Haşmet Hanağası 0000-0002-4624-4428 Seyhun Topbaş 0000-0003-2515-3874
Early Pub Date	May 29, 2025
Publication Date	July 4, 2025
Submission Date	December 13, 2024
Acceptance Date	February 26, 2025
Published in Issue	Year 2025 Volume: 11 Issue: 4

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AMA	Bingöl D, Bengisu S, Tüfekçioğlu Z, Demirsoy EN, Hanağası H, Topbaş S. The effect of swallowing disorder on quality of life in patients with Parkinson’s disease. Eur Res J. July 2025;11(4):697-704. doi:10.18621/eurj.1600087

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