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Bitkilerden biyoaktif bileşiklerin ultrases destekli ekstraksiyonu

Year 2026, Issue: 35, 1 - 12

Murat Özdemir , İrem Ak , Seray Coşkun , Nursima Ünverdi

https://doi.org/10.56833/gidaveyem.1713475

Abstract

Amaç: Bu çalışma, ultrases destekli ekstraksiyonun mekanizması, avantajları ve dezavantajları, biyoaktif bileşiklerin ultrases destekli ekstraksiyonunu etkileyen önemli faktörler ve bitkilerden fenolik ve flavonoidlerin ekstraksiyonunda ultrases destekli ekstraksiyonun mevcut uygulamaları hakkında kapsamlı bir değerlendirme sunmaktadır. Bu derleme çalışmasının temel amacı, bitkilerden fenolik ve flavonoidlerin elde edilmesinde ultrases destekli ekstraksiyonun prensipleri, faydaları ve etkisi hakkında kapsamlı bilgiler vermek, ultrases destekli ekstraksiyonda kullanılan ekipmanları (ultrasonik prob ve ultrasonik banyo) incelemek, bitkilerden fenolik ve flavonoid bileşiklerin geri kazanılmasında ultrases destekli ekstraksiyon hakkında bir bakış açısı sunmaktır. Bu derleme, ultrases destekli ekstraksiyonun kullanım kolaylığı, artan verimlilik ve tekrarlanabilirlik, azaltılmış solvent kullanımı, enerji tüketimi, işletme maliyetleri ve işlem süresi, iyileştirilmiş ürün saflığı, ısıya duyarlı bileşiklerin biyoaktivitesinin daha iyi korunması ile oda sıcaklığında ve atmosferik basınçta çalıştırılabilir olması gibi çok sayıda avantaj sağladığını ortaya koymaktadır. Sıcaklık, temas süresi, çözücü tipi, katı-çözücü oranı, ultrasonik güç ve ultrasonik frekans biyoaktif bileşiklerin ultrason destekli ekstraksiyonunu etkileyen başlıca faktörlerdir. Ultrases destekli ekstraksiyon sırasındaki kavitasyon, bitki hücrelerinden biyoaktif bileşiklerin salınımını hızlandırmakta ve böylece daha verimli bir ekstraksiyon sağlamaktadır.

Sonuç: Ultrases destekli ekstraksiyonun bitkilerden biyoaktif bileşiklerin ekstraksiyonu için yenilikçi bir yöntem ve etkili bir yol olduğu görülmektedir. Sonuç olarak, bitkilerden fenolik ve flavonoid bileşiklerin ekstraksiyonuna ilişkin uygulamalar, ultrases destekli ekstraksiyonun çevre dostu bir yöntem olduğunu ve bu nedenle yeşil ekstraksiyon olarak bilindiğini göstermektedir.

Keywords

Ultrases destekli ekstraksiyon bitkiler biyoaktif bileşikler fenolikler flavonoidler

References

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Ultrasound-assisted extraction of bioactive compounds from plants

Year 2026, Issue: 35, 1 - 12

Murat Özdemir , İrem Ak , Seray Coşkun , Nursima Ünverdi

https://doi.org/10.56833/gidaveyem.1713475

Abstract

Objective: This study gives a comprehensive review of the mechanism, advantages and disadvantages of ultrasound-assisted extraction, important factors affecting the ultrasound-assisted extraction of bioactive compounds, and current applications of ultrasound-assisted extraction in extraction of phenolics and flavonoids from plant materials. The primary goal of this review is to gain a thorough understanding of the principles, benefits and impact of ultrasound-assisted extraction on phenolics and flavonoids from plants, investigate the equipment (ultrasonic probe and ultrasonic bath) used in ultrasound-assisted extraction, and provide an overview of ultrasound-assisted extraction in the recovery of phenolic and flavonoid compounds from plants. This review reveals that ultrasound-assisted extraction provides numerous advantages, including its ease of use, increased efficiency and reproducibility, reduced solvent usage, energy consumption, operating costs and processing time, improved product purity, better protection of bioactivity of thermosensitive compounds, and operable at room temperature and atmospheric pressure. Temperature, contact time, solvent type and solvent concentration, solid to solvent ratio, ultrasonic power and ultrasonic frequency are the primary factors affecting ultrasound-assisted extraction of bioactive compounds. Cavitation during ultrasound-assisted extraction accelerates the release of bioactive compounds from plant cells, thus resulting in more efficient extraction.

Conclusion: It is considered that ultrasound-assisted extraction is an innovative method and efficient way to extract bioactive compounds from plants. In conclusion, applications regarding the extraction of phenolic and flavonoid compounds from plants show that ultrasound-assisted extraction is an environmentally friendly method, which is why it is known as green extraction.

Keywords

Ultrasound-assisted extraction plants bioactive compounds phenolics flavonoids

References

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  • Chen, F.Y., Yu, W.W., Lin, F.X., Huang, J.W., Huang, W.M., Shuang, P.C., Bian, Y.T., and Luo, Y.M. (2021). Sesquiterpenoids with neuroprotective activities from the Chloranthaceae plant Chloranthus henryi. Fitoterapia, 151, 104871. https://doi.org/10.1016/j.fitote.2021.104871
  • Chen, Y., Li, M., Dharmasiri, T.S.K., Song, X., Liu, F., and Wang, X. (2020). Novel ultrasonic-assisted vacuum drying technique for dehydrating garlic slices and predicting the quality properties by low field nuclear magnetic resonance. Food Chemistry, 306, 125625. https://doi.org/10.1016/j.foodchem.2019.125625
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  • Fu, X., Wang, D., Belwal, T., Xie, J., Xu, Y., Li, L., Zou, L., Zhang, L., and Luo, Z. (2021). Natural deep eutectic solvent enhanced pulse-ultrasonication assisted extraction as a multi-stability protective and efficient green strategy to extract anthocyanin from blueberry pomace. LWT-Food Science and Technology, 144, 111220. https://doi.org/10.1016/j.lwt.2021.111220
  • Kopustinskiene, D.M., Jakstas, V., Savickas, A., and Bernatoniene, J. (2020). Flavonoids as anti-cancer agents. Nutrients, 12(2), 457. https://doi.org/10.3390/nu12020457
  • Lama-Muñoz, A., and Contreras, M.D.M. (2022). Extraction systems and analytical techniques for food phenolic compounds: A review. Foods, 11(22), 3671. https://doi.org/10.3390/foods11223671
  • Liao, J., Guo, Z., and Yu, G. (2021). Process intensification and kinetic studies of ultrasound-assisted extraction of flavonoids from peanut shells. Ultrasonics Sonochemistry, 76, 105661. https://doi.org/10.1016/j.ultsonch.2021.105661
  • Liga, S., Paul, C., and Péter, F. (2023). Flavonoids: Overview of biosynthesis, biological activity, and current extraction techniques. Plants, 12(14), 2732. https://doi.org/10.3390/plants12142732
  • Lin, X., Wu, L., Wang, X., Yao, L., and Wang, L. (2021). Ultrasonic-assisted extraction for flavonoid compounds content and antioxidant activities of India Moringa oleifera L. leaves: Simultaneous optimization, HPLC characterization and comparison with other methods. Journal of Applied Research on Medicinal and Aromatic Plants, 20, 100284. https://doi.org/10.1016/j.jarmap.2020.100284
  • Mahindrakar, K.V., and Rathod, V.K. (2020). Ultrasonic assisted aqueous extraction of catechin and gallic acid from Syzygium cumini seed kernel and evaluation of total phenolic, flavonoid contents and antioxidant activity. Chemical Engineering and Processing-Process Intensification, 149, 107841. https://doi.org/10.1016/j.cep.2020.107841
  • Mai, X., Liu, Y., Tang, X., Wang, L., Lin, Y., Zeng, H., Luo, L., Fan, H., and Li, P. (2020). Sequential extraction and enrichment of flavonoids from Euonymus alatus by ultrasonic-assisted polyethylene glycol-based extraction coupled to temperature-induced cloud point extraction. Ultrasonics Sonochemistry, 66, 105073. https://doi.org/10.1016/j.ultsonch.2020.105073
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There are 47 citations in total.

Details

Primary Language English
Subjects Food Engineering
Journal Section Review Papers
Authors

Murat Özdemir 0000-0001-9025-3068

İrem Ak 0009-0007-8919-572X

Seray Coşkun 0009-0009-3164-5008

Nursima Ünverdi 0009-0006-4376-407X

Early Pub Date June 3, 2025
Publication Date
Submission Date August 10, 2024
Acceptance Date February 3, 2025
Published in Issue Year 2026 Issue: 35

Cite

APA Özdemir, M., Ak, İ., Coşkun, S., Ünverdi, N. (2025). Ultrasound-assisted extraction of bioactive compounds from plants. Gıda Ve Yem Bilimi Teknolojisi Dergisi(35), 1-12. https://doi.org/10.56833/gidaveyem.1713475

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Gıda ve Yem Bilimi-Teknolojisi Dergisi  CC BY-NC-ND 4.0 lisansı altında lisanslanmıştır
 Journal of Food and Feed Science-Technology is licensed under CC BY-NC-ND 4.0