Abstract
Wild honey intoxication (WHI) is a rare disease that results from consuming honey produced by Rhododendron polen feeded bees. WHI develops due to grayanotoxin (GT) that it contains. WHI might present with mild symptoms of gastrointestinal, cardiovascular and neurological systems or might also present in a life threatining form with AV block and cardiovascular collaps. In this report we aimed to present clinical presentation and treatment of a case of WHI.
Keywords
References
- 1. Lampe KF. Rhododendrons, mountain laurel, and mad honey. JAMA 1988;259: 2009.
- 2. Koca I, Koca AF. Poisoning by mad honey: a brief review. Food Chem Toxicol 2007;45: 1315–8.
- 3. Seyama I, Yamaoka K, Yakehiro M, et al. Is the site of action of grayanotoxin the sodium channel gating of squid axon? Jpn J Physiol 1985;35: 401–10.
- 4. Gossinger H, Hruby K, Haubenstock A, et al. Cardiac arrhythmias in a patient with grayanotoxin-honey poisoning. Vet Hum Toxicol 1983;25: 328–9.
- 5. Gündüz A, Tatlı Ö, Türedi S. Geçmişten günü-müze deli bal zehirlenmesi. Turk J Emerg Med 2008;8:46-9.
- 6. Gündüz A, Turedi S, Uzun H, et al. Mad honey poisoning. Am J Emerg Med 2006; 24: 595-8.
- 7. Von Malottki K, Wiechmann HW. Acute lifethreatening bradycardia: Food poisoning by Turkish wild honey. Dtsch Med Wochenschr. 1996; 121(30): 936-8.
- 8. Curtis KD. Toxicology the Basic Science of Poisons 6th ed. McGraw-Hill, 2001:969.
- 9. Sutlupinar N, Mat A, Satganoglu Y. Poisoning by toxic honey in Turkey. Arch Toxicol. 1993; 67(2): 148-50.
- 10. Gündüz A, Meriçé ES, Baydın A, et al. Does mad honey poisoning require hospital admission? Am J Emerg Med 2009;27:424-7.
- 11. Hancı V, Bilir S, Kırtaç N, ve ark. Zonguldak Bölgesinde Deli Bal Zehirlenmesi: Yetmiş İki Olgunun Analizi. Türk Anest Rean Der Dergisi 2010; 38(4): 278-84.
- 12. Binnetoglu E, Dindar S, Şengül E, ve ark. Deli Bal Zehirlenmesi; Ne Kadar Gözleyelim? Abant Medical Journal. Yıl: 2012 Cilt: 1 Sayı: 1 32-34
- 13. Cagli KE, Tufekcioglu O, Sen N, et al. Atrioventricular Block Induced by Mad-Honey Intoxication. Confirmation of Diagnosis by Pollen Analysis. Tex Heart Inst J. 2009; 36(4): 342– 344
Abstract
Deli Bal Zehirlenmesi (DBZ), Rhododendron polenleriyle beslenen arıların ürettiği taze balın tüketilmesi ile görülen bir besin zehirlenmesi tablosudur. Toksik etkileri balın içerdiği grayanotoksin (GT) nedeniyle meydana gelir. Zehirlenme tablosunda gastrointestinal, kardiyovasküler ve nörolojik sistem bulguları görülmekte olup AV tam blok ve kardiyovasküler kollaps gibi hayati tehdit edici etkileri olabilir. Bu olguda deli bal zehirlenmesi semptomlarıyla acil servise başvuran hastanın tanı ve tedavisini sunmayı amaçladık.
Keywords
References
- 1. Lampe KF. Rhododendrons, mountain laurel, and mad honey. JAMA 1988;259: 2009.
- 2. Koca I, Koca AF. Poisoning by mad honey: a brief review. Food Chem Toxicol 2007;45: 1315–8.
- 3. Seyama I, Yamaoka K, Yakehiro M, et al. Is the site of action of grayanotoxin the sodium channel gating of squid axon? Jpn J Physiol 1985;35: 401–10.
- 4. Gossinger H, Hruby K, Haubenstock A, et al. Cardiac arrhythmias in a patient with grayanotoxin-honey poisoning. Vet Hum Toxicol 1983;25: 328–9.
- 5. Gündüz A, Tatlı Ö, Türedi S. Geçmişten günü-müze deli bal zehirlenmesi. Turk J Emerg Med 2008;8:46-9.
- 6. Gündüz A, Turedi S, Uzun H, et al. Mad honey poisoning. Am J Emerg Med 2006; 24: 595-8.
- 7. Von Malottki K, Wiechmann HW. Acute lifethreatening bradycardia: Food poisoning by Turkish wild honey. Dtsch Med Wochenschr. 1996; 121(30): 936-8.
- 8. Curtis KD. Toxicology the Basic Science of Poisons 6th ed. McGraw-Hill, 2001:969.
- 9. Sutlupinar N, Mat A, Satganoglu Y. Poisoning by toxic honey in Turkey. Arch Toxicol. 1993; 67(2): 148-50.
- 10. Gündüz A, Meriçé ES, Baydın A, et al. Does mad honey poisoning require hospital admission? Am J Emerg Med 2009;27:424-7.
- 11. Hancı V, Bilir S, Kırtaç N, ve ark. Zonguldak Bölgesinde Deli Bal Zehirlenmesi: Yetmiş İki Olgunun Analizi. Türk Anest Rean Der Dergisi 2010; 38(4): 278-84.
- 12. Binnetoglu E, Dindar S, Şengül E, ve ark. Deli Bal Zehirlenmesi; Ne Kadar Gözleyelim? Abant Medical Journal. Yıl: 2012 Cilt: 1 Sayı: 1 32-34
- 13. Cagli KE, Tufekcioglu O, Sen N, et al. Atrioventricular Block Induced by Mad-Honey Intoxication. Confirmation of Diagnosis by Pollen Analysis. Tex Heart Inst J. 2009; 36(4): 342– 344
Details
| Primary Language | Turkish |
|---|---|
| Journal Section | Case Report |
| Authors | |
| Publication Date | September 1, 2013 |
| Published in Issue | Year 2013 Volume: 3 Issue: 3 |