Abstract
Vocal cord paralysis is a clinical finding that can occur due to intra- and extralaryngeal pathologies. Cardio-vocal syndrome, also known as Ortner syndrome among extralaryngeal pathologies, is left vocal cord paralysis that develops due to cardiovascular pathologies. A 48-year-old female patient who had a complaint of hoarseness for 3 months underwent a contrast-enhanced neck magnetic resonance imaging and non-contrast thorax computerized tomography examination upon detection of left vocal cord paralysis during physical examination, and no pathology was detected. In addition to the patient's obesity and shortness of breath, the cardiology department was consulted and a transthoracic echocardiography was performed, and pulmonary artery hypertension was diagnosed. No additional pathology was detected in the patient and Ortner syndrome was diagnosed. Cardiac and pulmonary diseases were investigated in the patient with pulmonary artery hypertension. It was considered as secondary pulmonary arterial hypertension due to arterial hypertension and medical treatment was started. Pulmonary arterial hypertension was measured as 50 mmHg in the first measurements and 28 mmHg in the 3rd month control after treatment. Left vocal cord paraly-sis still continues, but the patient's complaints of shortness of breath and hoarseness have decrea-sed. In the evaluation of patients presenting with hoarseness, extralaryngeal pathologies should be taken into consideration in the etiology and cardiac diseases such as pulmonary arterial hyperten-sion should be kept in mind.
References
- 1. Cantarella G, Dejonckere P, Galli A, Ciabatta A, Gaffuri M, Pignataro L, Torretta S. A retrospective evaluation of the etiology of unilateral vocal fold paralysis over the last 25 years. Eur Arch Otorhinolaryngol. 2017 Jan;274(1):347-353.
- 2. Williamson AJ, Shermetaro C. Unilateral Vocal Cord Paraly-sis(Archived). 2023 Aug 8. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan. PMID: 30571041.
- 3. Kaya Ö, Yoldaş T, Karademir S, Örün UA, Sarı E. A pediatric case of Ortner`s syndrome caused by heritable pulmonary arterial hypertension and review of the literature. Turk J Pediatr. 2019;61(6):963-966.
- 4. Duyuler S, Bayır PT, Korkmaz A, Güray Y, Özcan E (March 1, 2015) Hoarseness Secondary To Cardiovascular Disease: Cardiovocal Sydrome In a Patient With Pulmonary Artery Aneurysm and Giant Atria. Acıbadem Üniversitesi Sağlık Bi-limleri Dergisi 1 49–51.
- 5. Verma S, Talwar A, Talwar A, Khan S, Krishnasastry KV, Talwar A. Ortner's syndrome: A systematic review of pre-sentation, diagnosis and management. Intractable Rare Dis Res. 2023 Aug;12(3):141-147..
- 6. Pahal P, Sharma S. Secondary Pulmonary Hypertension. 2023 Aug 7. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–. PMID: 30252264.
- 7. Marchiori E, Hochhegger B, Zanetti G. Pulmonary hyperten-sion. J Bras Pneumol. 2023 Oct 30;49(5):e20230275.
Abstract
Vokal kord paralizileri intra ve ekstralarengeal patolojilere bağlı olarak ortaya çıkabilen bir klinik bulgudur. Ekstralaringeal patolojilerden Ortner sendromu olarak da bilinen kardiyovokal sendrom, kardiyovasküler pa-tolojilere bağlı olarak gelişen sol vokal kord paralizisidir. 3 aydır ses kısıklığı yakınması bulunan 48 yaşında kadın hasta, fizik muayenesinde sol vokal kord paralizisi saptanması üzerine kontrastlı boyun manyetik rezo-nans incelemesi ve kontrastsız toraks bilgisayarlı tomagrofi incelemesi yapılmış herhangi bir patoloji saptan-mamıştır. Hastanın ek olarak obezitesinin olması ve nefes darlığı yaşıyor olması nedeni ile kardiyoloji bölü-müne konsulte edilmiş yapılan transtorasik ekokardiyografide pulmoner arter hipertansiyonu tanısı almıştır. Ek patoloji saptanmayan hasta Ortner sendromu tanısı almıştır. Pulmoner arter hipertansiyonu olan hastada kardiyak ve pulmoner hastalıklar araştırıldı. Arteriyel hipertansiyona bağlı sekonder pulmoner arter hipertan-siyonu olarak düşünüldu ve medikal tedavi başlandı. Pulmoner arter hipertansiyonu ilk ölçümlerde 50 mmHg iken tedavi sonrası 3. ay kontrolünde 28mmHg ölçüldü. Sol vokal kord paralizisi ise halen devam etmekte an-cak hastanın nefes darlığı ve ses kısıklığı şikayeti azaldı. Ses kısıklığı ile başvuran hastaların değerlendirilme-sinde etiyolojide ekstralaringeal patolojiler dikkate alınmalı, pulmoner arter hipertansiyonu gibi kardiyak has-talıklar akılda tutulmalıdır.
Ethical Statement
olgu sunumu oldugu için hasta onam belgesi eklenmiştir
References
- 1. Cantarella G, Dejonckere P, Galli A, Ciabatta A, Gaffuri M, Pignataro L, Torretta S. A retrospective evaluation of the etiology of unilateral vocal fold paralysis over the last 25 years. Eur Arch Otorhinolaryngol. 2017 Jan;274(1):347-353.
- 2. Williamson AJ, Shermetaro C. Unilateral Vocal Cord Paraly-sis(Archived). 2023 Aug 8. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan. PMID: 30571041.
- 3. Kaya Ö, Yoldaş T, Karademir S, Örün UA, Sarı E. A pediatric case of Ortner`s syndrome caused by heritable pulmonary arterial hypertension and review of the literature. Turk J Pediatr. 2019;61(6):963-966.
- 4. Duyuler S, Bayır PT, Korkmaz A, Güray Y, Özcan E (March 1, 2015) Hoarseness Secondary To Cardiovascular Disease: Cardiovocal Sydrome In a Patient With Pulmonary Artery Aneurysm and Giant Atria. Acıbadem Üniversitesi Sağlık Bi-limleri Dergisi 1 49–51.
- 5. Verma S, Talwar A, Talwar A, Khan S, Krishnasastry KV, Talwar A. Ortner's syndrome: A systematic review of pre-sentation, diagnosis and management. Intractable Rare Dis Res. 2023 Aug;12(3):141-147..
- 6. Pahal P, Sharma S. Secondary Pulmonary Hypertension. 2023 Aug 7. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan–. PMID: 30252264.
- 7. Marchiori E, Hochhegger B, Zanetti G. Pulmonary hyperten-sion. J Bras Pneumol. 2023 Oct 30;49(5):e20230275.
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Otorhinolaryngology |
| Journal Section | Case Report |
| Authors | |
| Early Pub Date | June 26, 2025 |
| Publication Date | June 27, 2025 |
| Submission Date | January 30, 2025 |
| Acceptance Date | April 29, 2025 |
| Published in Issue | Year 2025 Volume: 22 Issue: 2 |
Harran Üniversitesi Tıp Fakültesi Dergisi / Journal of Harran University Medical Faculty