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Oral pharmabiotic tablet formulations

Year 2024, Volume: 28 Issue: 1, 236 - 247, 28.06.2025

Buse Kandur Timuçin Uğurlu , Erkan Rayaman , Sevinç Şahbaz

Abstract

Pharmabiotic is a unique and recent term used to describe formulations containing probiotics. Pharmabiotics are probiotics prepared in a pharmaceutical form used to treat diseases and disorders by making physicochemical changes in human health. Probiotics, prebiotics, and synbiotics are included in this scope, and enzobiotics, which are a rising class of supplements, should be evaluated in this context, as they are a subspecies of synbiotics. Pharmabiotics, unlike nutribiotics, do not necessarily contain live microorganisms. The best examples of these are paraprobiotics and postbiotics. Tablet formulations are suitable dosage forms for pharmabiotics due to their redundant superiority over other solid dosage forms. Tablets are frequently preferred because they can be produced at low cost, are easily transported, and modified, are suitable for large-scale production, and are more stable than other dosage forms. Considering the examples in the literature and the definition of pharmabiotic, several tablet formulations can be mentioned as pharmabiotics. They can be divided into conventional uncoated tablets, chewable tablets, and effervescent tablets. With recent studies, this classification has expanded, and buccal mucoadhesive tablets, ODTs (orally disintegrating tablets) and FDTs (fast disintegrating tablets), layered/multi-layered tablets, and tablets within tablets have also taken their place in the classification. This article focuses on oral tablet formulations that can be classified as pharmabiotics.

Keywords

pharmabiotic probiotic prebiotic types of tablets formulation

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Details

Primary Language English
Subjects Pharmaceutical Delivery Technologies
Journal Section Reviews
Authors

Buse Kandur 0009-0004-9526-3344

Timuçin Uğurlu 0000-0002-8874-5941

Erkan Rayaman 0000-0002-1261-3942

Sevinç Şahbaz 0000-0001-9195-5563

Publication Date June 28, 2025
Published in Issue Year 2024 Volume: 28 Issue: 1

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APA Kandur, B., Uğurlu, T., Rayaman, E., Şahbaz, S. (2025). Oral pharmabiotic tablet formulations. Journal of Research in Pharmacy, 28(1), 236-247.
AMA Kandur B, Uğurlu T, Rayaman E, Şahbaz S. Oral pharmabiotic tablet formulations. J. Res. Pharm. June 2025;28(1):236-247.
Chicago Kandur, Buse, Timuçin Uğurlu, Erkan Rayaman, and Sevinç Şahbaz. “Oral Pharmabiotic Tablet Formulations”. Journal of Research in Pharmacy 28, no. 1 (June 2025): 236-47.
EndNote Kandur B, Uğurlu T, Rayaman E, Şahbaz S (June 1, 2025) Oral pharmabiotic tablet formulations. Journal of Research in Pharmacy 28 1 236–247.
IEEE B. Kandur, T. Uğurlu, E. Rayaman, and S. Şahbaz, “Oral pharmabiotic tablet formulations”, J. Res. Pharm., vol. 28, no. 1, pp. 236–247, 2025.
ISNAD Kandur, Buse et al. “Oral Pharmabiotic Tablet Formulations”. Journal of Research in Pharmacy 28/1 (June 2025), 236-247.
JAMA Kandur B, Uğurlu T, Rayaman E, Şahbaz S. Oral pharmabiotic tablet formulations. J. Res. Pharm. 2025;28:236–247.
MLA Kandur, Buse et al. “Oral Pharmabiotic Tablet Formulations”. Journal of Research in Pharmacy, vol. 28, no. 1, 2025, pp. 236-47.
Vancouver Kandur B, Uğurlu T, Rayaman E, Şahbaz S. Oral pharmabiotic tablet formulations. J. Res. Pharm. 2025;28(1):236-47.