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In silico investigation of wound healing potential of some compounds in tubers of Asphodelus species with GSK3-β protein

Year 2021, Volume: 25 Issue: 5, 747 - 754, 28.06.2025

Halil Aksoy , Turgut Şekerler , Naz Mina Mert

Abstract

Wound healing is a process that involves biochemical processes such as inflammation and cell proliferation and is controlled by many proteins. It is known that one of the most effective factors in this process is the inhibition of GSK3-β protein. In current study, in silico wound healing activity of the some compounds found in the tubers of Asphodelus species used as a wound healing in traditional medicine were investigated. For this purpose, the interactions between the compounds and GSK3-β protein were studied in silico. As a result of the study, it has been determined that and stigmasterol, β-sitosterol and emodin molecules are effective.

Keywords

Asphodelus species β-sitosterol emodin GSK3-β protein stigmasterol wound healing activity

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There are 17 citations in total.

Details

Primary Language English
Subjects Pharmaceutical Biochemistry
Journal Section Articles
Authors

Halil Aksoy

Turgut Şekerler

Naz Mina Mert

Publication Date June 28, 2025
Published in Issue Year 2021 Volume: 25 Issue: 5

Cite

APA Aksoy, H., Şekerler, T., & Mert, N. M. (2025). In silico investigation of wound healing potential of some compounds in tubers of Asphodelus species with GSK3-β protein. Journal of Research in Pharmacy, 25(5), 747-754.
AMA Aksoy H, Şekerler T, Mert NM. In silico investigation of wound healing potential of some compounds in tubers of Asphodelus species with GSK3-β protein. J. Res. Pharm. July 2025;25(5):747-754.
Chicago Aksoy, Halil, Turgut Şekerler, and Naz Mina Mert. “In Silico Investigation of Wound Healing Potential of Some Compounds in Tubers of Asphodelus Species With GSK3-β Protein”. Journal of Research in Pharmacy 25, no. 5 (July 2025): 747-54.
EndNote Aksoy H, Şekerler T, Mert NM (July 1, 2025) In silico investigation of wound healing potential of some compounds in tubers of Asphodelus species with GSK3-β protein. Journal of Research in Pharmacy 25 5 747–754.
IEEE H. Aksoy, T. Şekerler, and N. M. Mert, “In silico investigation of wound healing potential of some compounds in tubers of Asphodelus species with GSK3-β protein”, J. Res. Pharm., vol. 25, no. 5, pp. 747–754, 2025.
ISNAD Aksoy, Halil et al. “In Silico Investigation of Wound Healing Potential of Some Compounds in Tubers of Asphodelus Species With GSK3-β Protein”. Journal of Research in Pharmacy 25/5 (July 2025), 747-754.
JAMA Aksoy H, Şekerler T, Mert NM. In silico investigation of wound healing potential of some compounds in tubers of Asphodelus species with GSK3-β protein. J. Res. Pharm. 2025;25:747–754.
MLA Aksoy, Halil et al. “In Silico Investigation of Wound Healing Potential of Some Compounds in Tubers of Asphodelus Species With GSK3-β Protein”. Journal of Research in Pharmacy, vol. 25, no. 5, 2025, pp. 747-54.
Vancouver Aksoy H, Şekerler T, Mert NM. In silico investigation of wound healing potential of some compounds in tubers of Asphodelus species with GSK3-β protein. J. Res. Pharm. 2025;25(5):747-54.