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Chemical compositions of aerial parts and root of Hypericum olympicum L. essential oils, and their antimicrobial activity screening

Year 2023, Volume: 27 Issue: 5, 2153 - 2159, 28.06.2025

Damla Kırcı , Yavuz Bülent Köse , Betül Demirci

Abstract

Hypericum olympicum L. (Hypericaceae) thrives in Turkey, S. Balkans, Greece, and Serbia. While the decoction prepared is internally used for stomachache; used externally for inflamed wounds and cuts in traditional. This research aims to examine the in vitro antimicrobial of the essential oil (EO) obtained using H. olympicum aerial parts. The EOs from H. olympicum aerial parts and roots were distilled and characterized by GC-FID and GC/MS systems, respectively. Germacrene D (26.4%) and α-pinene (8.5%) were found as the main components of the aerial parts of H. olympicum EO. The EO of H. olympicum root were characterized with undecane (38.9%), α-pinene (14.2%), and 3-methyl nonane (9.2%). The antimicrobial activity of EO of H. olympicum aerial parts was observed S. pyogenes (219 µg/mL), E. coli (8.75 mg/mL), S. aureus (109 µg/mL) and C. albicans (55 µg/mL). Essential oil of H. olympicum aerial parts is differently reported in the literature while the chemical composition of EO of H. olympicum root is identified for the first time. According to our findings, the essential oil of the H. olympicum aerial parts showed a strong effect against skin wound pathogens.

Keywords

Hypericum olympicum hypericaceae essential oil antimicrobial activity

References

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There are 22 citations in total.

Details

Primary Language English
Subjects Pharmacognosy
Journal Section Articles
Authors

Damla Kırcı 0000-0002-3479-3999

Yavuz Bülent Köse 0000-0002-3060-7271

Betül Demirci

Publication Date June 28, 2025
Published in Issue Year 2023 Volume: 27 Issue: 5

Cite

APA Kırcı, D., Köse, Y. B., & Demirci, B. (2025). Chemical compositions of aerial parts and root of Hypericum olympicum L. essential oils, and their antimicrobial activity screening. Journal of Research in Pharmacy, 27(5), 2153-2159.
AMA Kırcı D, Köse YB, Demirci B. Chemical compositions of aerial parts and root of Hypericum olympicum L. essential oils, and their antimicrobial activity screening. J. Res. Pharm. July 2025;27(5):2153-2159.
Chicago Kırcı, Damla, Yavuz Bülent Köse, and Betül Demirci. “Chemical Compositions of Aerial Parts and Root of Hypericum Olympicum L. Essential Oils, and Their Antimicrobial Activity Screening”. Journal of Research in Pharmacy 27, no. 5 (July 2025): 2153-59.
EndNote Kırcı D, Köse YB, Demirci B (July 1, 2025) Chemical compositions of aerial parts and root of Hypericum olympicum L. essential oils, and their antimicrobial activity screening. Journal of Research in Pharmacy 27 5 2153–2159.
IEEE D. Kırcı, Y. B. Köse, and B. Demirci, “Chemical compositions of aerial parts and root of Hypericum olympicum L. essential oils, and their antimicrobial activity screening”, J. Res. Pharm., vol. 27, no. 5, pp. 2153–2159, 2025.
ISNAD Kırcı, Damla et al. “Chemical Compositions of Aerial Parts and Root of Hypericum Olympicum L. Essential Oils, and Their Antimicrobial Activity Screening”. Journal of Research in Pharmacy 27/5 (July 2025), 2153-2159.
JAMA Kırcı D, Köse YB, Demirci B. Chemical compositions of aerial parts and root of Hypericum olympicum L. essential oils, and their antimicrobial activity screening. J. Res. Pharm. 2025;27:2153–2159.
MLA Kırcı, Damla et al. “Chemical Compositions of Aerial Parts and Root of Hypericum Olympicum L. Essential Oils, and Their Antimicrobial Activity Screening”. Journal of Research in Pharmacy, vol. 27, no. 5, 2025, pp. 2153-9.
Vancouver Kırcı D, Köse YB, Demirci B. Chemical compositions of aerial parts and root of Hypericum olympicum L. essential oils, and their antimicrobial activity screening. J. Res. Pharm. 2025;27(5):2153-9.