Determination and comparison of metal contents in simulated body fluid medium conditions of the plant species by flame atomic absorption spectrometry (FAAS)

Adil Umaz; Fırat Aydın; Özge Tokul Ölmez; Mehmet Fırat; Mehmet Öztürk; Abdulselam Ertaş; Işıl Aydın

Research Article

Determination and comparison of metal contents in simulated body fluid medium conditions of the plant species by flame atomic absorption spectrometry (FAAS)

Year 2022, Volume: 26 Issue: 5, 1281 - 1294, 28.06.2025

Adil Umaz , Fırat Aydın , Özge Tokul Ölmez Mehmet Fırat , Mehmet Öztürk , Abdulselam Ertaş , Işıl Aydın

Abstract

The importance of plants in folk medicine and scientific studies is increasing day by day. In this context, the plants pose a danger to human health when they are eaten by the public, consumed as herbal tea or used as medicinal plants especially the toxic metals in their composition. For this reason, determining the macro, micro and toxic element content in the plants is important for health. In this study; the metal contents of root and aerial parts of nine different Salvia species were determined and the chemometric evaluation of the obtained results was made. In the principal component analysis (PCA) made with 20 elements of Salvia species, it was determined that the first two principal components explained 62.60% of the variance and the first six principal components explained 92.70%. When PCA and hierarchical cluster analysis (HCA) results are evaluated; the parts of Salvia species root and aerial parts were determined that were not clearly separated and there was no regional grouping. In addition, Salvia species prepared as herbal tea was left to different simulated body fluid medium conditions, and the changes in metal contents were examined. It was determined that were taken up Cr, Cd, Pb, Cu, Zn metals in the simulated saliva fluid (SSF), Ni, Mn metals in the simulated gastric fluid (SGF), and Na, K metals in the simulated intestinal fluid (SIF). It was determined that Fe metal in almost all Salvia species was not taken from three simulated body fluid mediums. Thus, elements determined which were taken up in body fluid mediums.

Keywords

Salvia, chemometry, SSF, SGF, SIF, FAAS

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There are 24 citations in total.

Details

Primary Language	English
Subjects	Pharmacognosy, Pharmaceutical Chemistry
Journal Section	Articles
Authors	Adil Umaz 0000-0003-2438-5454 Fırat Aydın 0000-0002-0868-2769 Özge Tokul Ölmez 0000-0002-2093-4949 Mehmet Fırat 0000-0001-5814-614X Mehmet Öztürk 0000-0001-8932-4535 Abdulselam Ertaş 0000-0002-2193-8386 Işıl Aydın
Publication Date	June 28, 2025
Published in Issue	Year 2022 Volume: 26 Issue: 5

Cite

APA	Umaz, A., Aydın, F., Ölmez, Ö. T., Fırat, M., et al. (2025). Determination and comparison of metal contents in simulated body fluid medium conditions of the plant species by flame atomic absorption spectrometry (FAAS). Journal of Research in Pharmacy, 26(5), 1281-1294.
AMA	Umaz A, Aydın F, Ölmez ÖT, Fırat M, Öztürk M, Ertaş A, Aydın I. Determination and comparison of metal contents in simulated body fluid medium conditions of the plant species by flame atomic absorption spectrometry (FAAS). J. Res. Pharm. June 2025;26(5):1281-1294.
Chicago	Umaz, Adil, Fırat Aydın, Özge Tokul Ölmez, Mehmet Fırat, Mehmet Öztürk, Abdulselam Ertaş, and Işıl Aydın. “Determination and Comparison of Metal Contents in Simulated Body Fluid Medium Conditions of the Plant Species by Flame Atomic Absorption Spectrometry (FAAS)”. Journal of Research in Pharmacy 26, no. 5 (June 2025): 1281-94.
EndNote	Umaz A, Aydın F, Ölmez ÖT, Fırat M, Öztürk M, Ertaş A, Aydın I (June 1, 2025) Determination and comparison of metal contents in simulated body fluid medium conditions of the plant species by flame atomic absorption spectrometry (FAAS). Journal of Research in Pharmacy 26 5 1281–1294.
IEEE	A. Umaz, F. Aydın, Ö. T. Ölmez, M. Fırat, M. Öztürk, A. Ertaş, and I. Aydın, “Determination and comparison of metal contents in simulated body fluid medium conditions of the plant species by flame atomic absorption spectrometry (FAAS)”, J. Res. Pharm., vol. 26, no. 5, pp. 1281–1294, 2025.
ISNAD	Umaz, Adil et al. “Determination and Comparison of Metal Contents in Simulated Body Fluid Medium Conditions of the Plant Species by Flame Atomic Absorption Spectrometry (FAAS)”. Journal of Research in Pharmacy 26/5 (June 2025), 1281-1294.
JAMA	Umaz A, Aydın F, Ölmez ÖT, Fırat M, Öztürk M, Ertaş A, Aydın I. Determination and comparison of metal contents in simulated body fluid medium conditions of the plant species by flame atomic absorption spectrometry (FAAS). J. Res. Pharm. 2025;26:1281–1294.
MLA	Umaz, Adil et al. “Determination and Comparison of Metal Contents in Simulated Body Fluid Medium Conditions of the Plant Species by Flame Atomic Absorption Spectrometry (FAAS)”. Journal of Research in Pharmacy, vol. 26, no. 5, 2025, pp. 1281-94.
Vancouver	Umaz A, Aydın F, Ölmez ÖT, Fırat M, Öztürk M, Ertaş A, Aydın I. Determination and comparison of metal contents in simulated body fluid medium conditions of the plant species by flame atomic absorption spectrometry (FAAS). J. Res. Pharm. 2025;26(5):1281-94.

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