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Foot Deodorizing Gel Formulation Having Antimicrobial Activity

Year 2023, Volume: 27 Issue: 3, 1260 - 1269, 28.06.2025

Prashant R. Patankar Vitthal V. Chopade Praveen D. Chaudhari

Abstract

Sweaty feet and foot odour are common nowadays. The existence of one or more of Staphylococcus
epidermis, Bacillus subtilis and Propionibacterium Acnes on foot surface may trigger the generation of isovaleric and
propionic acids, which in turn can cause a distinctive odor of feet. The present study tested susceptibility of Bacillus
subtilis and Staphylococcus epidermidis to various oils and oil combinations. The outcome showed that a combination of
lemon oil, neem oil and tulsi oil possessed synergistic antibacterial activity. A foot deodorizing gel containing a
combination of lemon oil, neem oil, and tulsi oil; a gel base was prepared and tested for stability, organoleptic
performance, antibacterial activity, irritation test, and deodorizing performance. The mixture of oils was found to
reduce at least 6 logs of the primary populace of B. subtilis and S. epidermidis in 10 min. The lethal effect was found for
at least 60 minutes. The gel formulation decreased at least 90% of the initial population of bacteria after 1 hour of contact
when checked for days 0, 15, 30 and 60. The gel formulation also showed desired properties such as clarity, pourability,
consistency, spreadability, quick absorption post application, non-stickiness and non-dryness, and absence of residue.
The foot deodorizing gel formulation demonstrated antibacterial efficiency against the bacteria responsible for
producing a strong foot odour.

Keywords

Foot odour Lemon oil Tulsi oil Neem oil Deodorant gel Bacillus subtilis Staphylococcus epidermidis

References

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There are 32 citations in total.

Details

Primary Language English
Subjects Pharmacology and Pharmaceutical Sciences (Other)
Journal Section Articles
Authors

Prashant R. Patankar

Vitthal V. Chopade 0000-0002-8810-8192

Praveen D. Chaudhari

Publication Date June 28, 2025
Published in Issue Year 2023 Volume: 27 Issue: 3

Cite

APA Patankar, P. R., Chopade, V. V., & Chaudhari, P. D. (2025). Foot Deodorizing Gel Formulation Having Antimicrobial Activity. Journal of Research in Pharmacy, 27(3), 1260-1269.
AMA Patankar PR, Chopade VV, Chaudhari PD. Foot Deodorizing Gel Formulation Having Antimicrobial Activity. J. Res. Pharm. June 2025;27(3):1260-1269.
Chicago Patankar, Prashant R., Vitthal V. Chopade, and Praveen D. Chaudhari. “Foot Deodorizing Gel Formulation Having Antimicrobial Activity”. Journal of Research in Pharmacy 27, no. 3 (June 2025): 1260-69.
EndNote Patankar PR, Chopade VV, Chaudhari PD (June 1, 2025) Foot Deodorizing Gel Formulation Having Antimicrobial Activity. Journal of Research in Pharmacy 27 3 1260–1269.
IEEE P. R. Patankar, V. V. Chopade, and P. D. Chaudhari, “Foot Deodorizing Gel Formulation Having Antimicrobial Activity”, J. Res. Pharm., vol. 27, no. 3, pp. 1260–1269, 2025.
ISNAD Patankar, Prashant R. et al. “Foot Deodorizing Gel Formulation Having Antimicrobial Activity”. Journal of Research in Pharmacy 27/3 (June 2025), 1260-1269.
JAMA Patankar PR, Chopade VV, Chaudhari PD. Foot Deodorizing Gel Formulation Having Antimicrobial Activity. J. Res. Pharm. 2025;27:1260–1269.
MLA Patankar, Prashant R. et al. “Foot Deodorizing Gel Formulation Having Antimicrobial Activity”. Journal of Research in Pharmacy, vol. 27, no. 3, 2025, pp. 1260-9.
Vancouver Patankar PR, Chopade VV, Chaudhari PD. Foot Deodorizing Gel Formulation Having Antimicrobial Activity. J. Res. Pharm. 2025;27(3):1260-9.