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Year 2020, Volume: 24 Issue: 5, 786 - 792, 27.06.2025

Vinodkumar Mugada , Pujitha Kondru Sai Navya Manda Mahalakshmi Vegi Smruthi Kakada

https://doi.org/10.35333/jrp.2020.231

Abstract

References

  • [1] White DK, Tudor-Locke C, Zhang Y, Fielding R, LaValley M, Felson DT, Gross KD, Nevitt MC, Lewis CE, Torner J, Neogi T. Daily walking and the risk of incident functional limitation in knee osteoarthritis: an observational study. Arthritis Care Res (Hoboken). 2014;66(9);1328-1336. [CrossRef]
  • [2] White DK, Lee J, Song J, Chang RW, Dunlop D. Potential functional benefit from light intensity physical activity in knee osteoarthritis. Am J Prev Med. 2017; 53(5):289-296. [CrossRef]
  • [3] Dunlop DD, Song J, Lee J, Gilbert AL, Semanik PA, Ehrlich-Jones L, Pellegrini CA, Pinto D, Ainsworth B, Chang RW. Physical Activity Minimum Threshold Predicting Improved Function in Adults with Lower-Extremity Symptoms. Arthritis Care Res (Hoboken). 2017; 69(4): 475-483. [CrossRef]
  • [4] Cross M, Smith E, Hoy D, Nolte S, Ackerman I, Fransen M, Bridgett L, Williams S, Guillemin F, Hill CL, Laslett LL, Jones G, Cicuttini F, Osborne R, Vos T, Buchbinder R, Woolf A, March L. The global burden of hip and knee osteoarthritis: estimates from the global burden of disease 2010 study. Ann Rheum Dis. 2014; 73(7): 1323-1330. [CrossRef]
  • [5] Pal CP, Singh P, Chaturvedi S, Pruthi KK, Vij A. Epidemiology of knee osteoarthritis in India and related factors. Indian J Orthop. 2016; 50(5): 518-522.
  • [6] Evcik D, Sonel B. Effectiveness of a home-based exercise therapy and walking program on osteoarthritis of the knee. Rheumatol Int. 2002; 22(3):103-106. [CrossRef]
  • [7] Sabirli F, Paker N, Bugdayci D. The relationship between Knee Injury and Osteoarthritis Outcome Score (KOOS) and Timed Up and Go test in patients with symptomatic knee osteoarthritis. Rheumatol Int. 2013; 33(10):2691-2694. [CrossRef]
  • [8] Roos EM, Roos HP, Lohmander LS, Ekdahl C, Beynnon BD. Knee Injury and Osteoarthritis Outcome Score (KOOS)- development of a self-administered outcome measure. J Orthop Sports Phys Ther. 1998; 28(2):88-96. [CrossRef]
  • [9] The Basics of Osteoarthritis 2020. https://www.webmd.com/osteoarthritis/guide/osteoarthritis-basics#1 (accessed 11th April 2020).
  • [10] Burgos-Vargas R, Cardiel MH, Loyola-Sanchez A, De Abreu MM, Pons-Estel BA, Rossignol M, Avouac B, Ferraz MB, Halhol H. Characterization of knee osteoarthritis in Latin America. A comparative analysis of clinical and health care utilization in Argentina, Brazil, and Mexico. Reumatol Clin. 2014; 10(3): 152-159. [CrossRef]
  • [11] Cubukcu D, Sarsan A, Alkan H. Relationships between Pain, Function, and Radiographic Findings in Osteoarthritis of the knee: A cross sectional study. Arthritis. 2012; 2012: 984060. [CrossRef]
  • [12] Narayan RV, Thabah MM, Poduval M. Neuropathic pain among patients with primary knee osteoarthritis- results of a cross sectional study from a tertiary care centre in Southern India. Indian J Rheumatol. 2017; 12(3): 132-138. [CrossRef]
  • [13] Bindawas S, Vishal V, Soham AS. Differences in Health-Related Quality of Life among Subjects with Frequent Bilateral or Unilateral Knee Pain: Data from the Osteoarthritis Initiative Study. J Orthop Sports Phys Ther. 2015; 45(2): 128-136. [CrossRef]
  • [14] Kulkarni K, Karssiens T, Kumar V, Pandit H. Obesity and osteoarthritis. Maturitas. 2016; 89: 22-28. [CrossRef]
  • [15] Larsen P, Engberg AS, Motahar I, Ostgaard SE, Elsoe R. Obesity infleunces the Knee Injury and Osteoarthritis Outcome Score. Joints. 2019; 7:8-12. [CrossRef]
  • [16] Edwards C, Rogers A, Lynch S, Pylawka T, Silvis M, Chinchilli V, Mosher T, Black K. The effects of bariatric surgery weight loss on knee pain in patients with osteoarthritis of the knee. Arthritis. 2012; 2012:504189. [CrossRef]
  • [17] Peeler J, Christian M, Cooper J, Leiter J, MacDonald P. Managing Knee Osteoarthritis: The Effects of Body Weight Supported Physical Activity on Joint Pain, Function, and Thigh Muscle Strength. Clin J Sport Med. 2015; 25(6):518- 523.
  • [18] Bowman EN, Hallock JD, Throckmorton TW, Azar FM. Hyaluronic acid injections for osteoarthritis of the knee: predictors of successful treatment. Int Orthop. 2018; 42(4): 733-740. [CrossRef]

Assessment of patient relevant outcomes in knee osteoarthritis patients using the Knee Injury and Osteoarthritis Outcome Score (KOOS) scale

Year 2020, Volume: 24 Issue: 5, 786 - 792, 27.06.2025

Vinodkumar Mugada , Pujitha Kondru Sai Navya Manda Mahalakshmi Vegi Smruthi Kakada

https://doi.org/10.35333/jrp.2020.231

Abstract

Knee osteoarthritis causes physical, functional limitations and difficulty in performing activities of daily living and mobility. The study aimed to assess patient-relevant outcomes in knee osteoarthritis patients using the Knee Injury and Osteoarthritis Outcome Score (KOOS) scale. A descriptive cross-sectional study was conducted on 120 patients. KOOS scale contains five subscales: pain, symptom, activities of daily living, sports/recreation, and quality of life. Score zero indicates the worst possible knee problems, while score 100 indicates no knee problems. Non-parametric tests, multiple linear regression analysis, and correlation were calculated for the data. The level of significance was p<0.05 and p<0.01. The mean age group of patients was 54.58±10.73 years. There was a statistically significant association observed between pain and disease duration (p=0.031); symptom and gender, comorbidities, and body mass index (p=0.038, 0.022, and 0.017, respectively); activities of daily living and knee surgery (p=0.043); sports/recreation and knee involved, disease duration (p=0.031, 0.033, respectively); and knee-related quality of life and gender (p=0.011). Knee surgery was an independent predictor for pain (p=0.008) and activities of daily living (p=0.008). There was a severe problem with sports/recreation in the patients. The knee-related quality of life was moderate. Knee surgery was found to be a strong independent predictor for pain and activities of daily living. However, socioeconomic status influenced the knee surgery in our patients.

Keywords

Pain Symptom activities of daily living; sports quality of life KOOS knee osteoarthritis

References

  • [1] White DK, Tudor-Locke C, Zhang Y, Fielding R, LaValley M, Felson DT, Gross KD, Nevitt MC, Lewis CE, Torner J, Neogi T. Daily walking and the risk of incident functional limitation in knee osteoarthritis: an observational study. Arthritis Care Res (Hoboken). 2014;66(9);1328-1336. [CrossRef]
  • [2] White DK, Lee J, Song J, Chang RW, Dunlop D. Potential functional benefit from light intensity physical activity in knee osteoarthritis. Am J Prev Med. 2017; 53(5):289-296. [CrossRef]
  • [3] Dunlop DD, Song J, Lee J, Gilbert AL, Semanik PA, Ehrlich-Jones L, Pellegrini CA, Pinto D, Ainsworth B, Chang RW. Physical Activity Minimum Threshold Predicting Improved Function in Adults with Lower-Extremity Symptoms. Arthritis Care Res (Hoboken). 2017; 69(4): 475-483. [CrossRef]
  • [4] Cross M, Smith E, Hoy D, Nolte S, Ackerman I, Fransen M, Bridgett L, Williams S, Guillemin F, Hill CL, Laslett LL, Jones G, Cicuttini F, Osborne R, Vos T, Buchbinder R, Woolf A, March L. The global burden of hip and knee osteoarthritis: estimates from the global burden of disease 2010 study. Ann Rheum Dis. 2014; 73(7): 1323-1330. [CrossRef]
  • [5] Pal CP, Singh P, Chaturvedi S, Pruthi KK, Vij A. Epidemiology of knee osteoarthritis in India and related factors. Indian J Orthop. 2016; 50(5): 518-522.
  • [6] Evcik D, Sonel B. Effectiveness of a home-based exercise therapy and walking program on osteoarthritis of the knee. Rheumatol Int. 2002; 22(3):103-106. [CrossRef]
  • [7] Sabirli F, Paker N, Bugdayci D. The relationship between Knee Injury and Osteoarthritis Outcome Score (KOOS) and Timed Up and Go test in patients with symptomatic knee osteoarthritis. Rheumatol Int. 2013; 33(10):2691-2694. [CrossRef]
  • [8] Roos EM, Roos HP, Lohmander LS, Ekdahl C, Beynnon BD. Knee Injury and Osteoarthritis Outcome Score (KOOS)- development of a self-administered outcome measure. J Orthop Sports Phys Ther. 1998; 28(2):88-96. [CrossRef]
  • [9] The Basics of Osteoarthritis 2020. https://www.webmd.com/osteoarthritis/guide/osteoarthritis-basics#1 (accessed 11th April 2020).
  • [10] Burgos-Vargas R, Cardiel MH, Loyola-Sanchez A, De Abreu MM, Pons-Estel BA, Rossignol M, Avouac B, Ferraz MB, Halhol H. Characterization of knee osteoarthritis in Latin America. A comparative analysis of clinical and health care utilization in Argentina, Brazil, and Mexico. Reumatol Clin. 2014; 10(3): 152-159. [CrossRef]
  • [11] Cubukcu D, Sarsan A, Alkan H. Relationships between Pain, Function, and Radiographic Findings in Osteoarthritis of the knee: A cross sectional study. Arthritis. 2012; 2012: 984060. [CrossRef]
  • [12] Narayan RV, Thabah MM, Poduval M. Neuropathic pain among patients with primary knee osteoarthritis- results of a cross sectional study from a tertiary care centre in Southern India. Indian J Rheumatol. 2017; 12(3): 132-138. [CrossRef]
  • [13] Bindawas S, Vishal V, Soham AS. Differences in Health-Related Quality of Life among Subjects with Frequent Bilateral or Unilateral Knee Pain: Data from the Osteoarthritis Initiative Study. J Orthop Sports Phys Ther. 2015; 45(2): 128-136. [CrossRef]
  • [14] Kulkarni K, Karssiens T, Kumar V, Pandit H. Obesity and osteoarthritis. Maturitas. 2016; 89: 22-28. [CrossRef]
  • [15] Larsen P, Engberg AS, Motahar I, Ostgaard SE, Elsoe R. Obesity infleunces the Knee Injury and Osteoarthritis Outcome Score. Joints. 2019; 7:8-12. [CrossRef]
  • [16] Edwards C, Rogers A, Lynch S, Pylawka T, Silvis M, Chinchilli V, Mosher T, Black K. The effects of bariatric surgery weight loss on knee pain in patients with osteoarthritis of the knee. Arthritis. 2012; 2012:504189. [CrossRef]
  • [17] Peeler J, Christian M, Cooper J, Leiter J, MacDonald P. Managing Knee Osteoarthritis: The Effects of Body Weight Supported Physical Activity on Joint Pain, Function, and Thigh Muscle Strength. Clin J Sport Med. 2015; 25(6):518- 523.
  • [18] Bowman EN, Hallock JD, Throckmorton TW, Azar FM. Hyaluronic acid injections for osteoarthritis of the knee: predictors of successful treatment. Int Orthop. 2018; 42(4): 733-740. [CrossRef]
There are 18 citations in total.

Details

Primary Language English
Subjects Pharmacology and Pharmaceutical Sciences (Other)
Journal Section Articles
Authors

Vinodkumar Mugada

Pujitha Kondru

Sai Navya Manda

Mahalakshmi Vegi

Smruthi Kakada

Publication Date June 27, 2025
Published in Issue Year 2020 Volume: 24 Issue: 5

Cite

APA Mugada, V., Kondru, P., Manda, S. N., Vegi, M., et al. (2025). Assessment of patient relevant outcomes in knee osteoarthritis patients using the Knee Injury and Osteoarthritis Outcome Score (KOOS) scale. Journal of Research in Pharmacy, 24(5), 786-792. https://doi.org/10.35333/jrp.2020.231
AMA Mugada V, Kondru P, Manda SN, Vegi M, Kakada S. Assessment of patient relevant outcomes in knee osteoarthritis patients using the Knee Injury and Osteoarthritis Outcome Score (KOOS) scale. J. Res. Pharm. June 2025;24(5):786-792. doi:10.35333/jrp.2020.231
Chicago Mugada, Vinodkumar, Pujitha Kondru, Sai Navya Manda, Mahalakshmi Vegi, and Smruthi Kakada. “Assessment of Patient Relevant Outcomes in Knee Osteoarthritis Patients Using the Knee Injury and Osteoarthritis Outcome Score (KOOS) Scale”. Journal of Research in Pharmacy 24, no. 5 (June 2025): 786-92. https://doi.org/10.35333/jrp.2020.231.
EndNote Mugada V, Kondru P, Manda SN, Vegi M, Kakada S (June 1, 2025) Assessment of patient relevant outcomes in knee osteoarthritis patients using the Knee Injury and Osteoarthritis Outcome Score (KOOS) scale. Journal of Research in Pharmacy 24 5 786–792.
IEEE V. Mugada, P. Kondru, S. N. Manda, M. Vegi, and S. Kakada, “Assessment of patient relevant outcomes in knee osteoarthritis patients using the Knee Injury and Osteoarthritis Outcome Score (KOOS) scale”, J. Res. Pharm., vol. 24, no. 5, pp. 786–792, 2025, doi: 10.35333/jrp.2020.231.
ISNAD Mugada, Vinodkumar et al. “Assessment of Patient Relevant Outcomes in Knee Osteoarthritis Patients Using the Knee Injury and Osteoarthritis Outcome Score (KOOS) Scale”. Journal of Research in Pharmacy 24/5 (June 2025), 786-792. https://doi.org/10.35333/jrp.2020.231.
JAMA Mugada V, Kondru P, Manda SN, Vegi M, Kakada S. Assessment of patient relevant outcomes in knee osteoarthritis patients using the Knee Injury and Osteoarthritis Outcome Score (KOOS) scale. J. Res. Pharm. 2025;24:786–792.
MLA Mugada, Vinodkumar et al. “Assessment of Patient Relevant Outcomes in Knee Osteoarthritis Patients Using the Knee Injury and Osteoarthritis Outcome Score (KOOS) Scale”. Journal of Research in Pharmacy, vol. 24, no. 5, 2025, pp. 786-92, doi:10.35333/jrp.2020.231.
Vancouver Mugada V, Kondru P, Manda SN, Vegi M, Kakada S. Assessment of patient relevant outcomes in knee osteoarthritis patients using the Knee Injury and Osteoarthritis Outcome Score (KOOS) scale. J. Res. Pharm. 2025;24(5):786-92.