Research Article
Year 2019,
Volume: 20 Issue: 2, 129 - 136, 31.08.2019
Abstract
References
- 1. Cao Y, Song M, Kim E, Shon W, Chugal N, Bogen G, et al. Pulp-dentin Regeneration: Current State and Future Prospects. J Dent Res 2015; 94: 1544-51.
- 2. Jung IY, Lee SJ, Hargreaves KM. Biologically based treatment of immature permanent teeth with pulpal necrosis: a case series. J Endod 2008; 34: 876-87.
- 3. Nabeel A, Prasanna N. Antiseptics and Antibiotics Used in Regenerative Endodontics. Int J Pharm and Clin Res 2013; 5: 141-4.
- 4. Sato I, Ando-Kurihara N, Kota K, Iwaku M, Hoshino E. Sterilization of infected root-canal dentine by topical application of a mixture of ciprofloxacin, metronidazole and minocycline in situ. Int Endod J 1996; 29: 118-24.
- 5. Kim JH, Kim Y, Shin SJ, Park JW, Jung IY. Tooth discoloration of immature permanent incisor associated with triple antibiotic therapy: a case report. J Endod 2010; 36: 1086-91.
- 6. Thibodeau B, Trope M. Pulp revascularization of a necrotic infected immature permanent tooth: case report and review of the literature. Pediatr Dent 2007; 29: 47-50.
- 7. Thomson A, Kahler B. Regenerative endodontics--biologically based treatment for immature permanent teeth: a case report and review of the literature. Aust Dent J 2010; 55: 446-52.
- 8. Sato T, Hoshino E, Uematsu H, Noda T. In vitro antimicrobial susceptibility to combinations of drugs on bacteria from carious and endodontic lesions of human deciduous teeth. Oral Microbiol Immunol 1993; 8: 172-6.
- 9. Iwaya SI, Ikawa M, Kubota M. Revascularization of an immature permanent tooth with apical periodontitis and sinus tract. Dent Traumatol 2001; 17: 185-7.
- 10. Berkhoff JA, Chen PB, Teixeira FB, Diogenes A. Evaluation of triple antibiotic paste removal by different irrigation procedures. J Endod 2014; 40: 1172-7.
- 11. Ruparel NB, Teixeira FB, Ferraz CC, Diogenes A. Direct effect of intracanal medicaments on survival of stem cells of the apical papilla. J Endod 2012; 38: 1372-5.
- 12. Banchs F, Trope M. Revascularization of immature permanent teeth with apical periodontitis: new treatment protocol? J Endod 2004; 30: 196-200.
- 13. Topçuoğlu HS, Aktı A, Topçuoğlu G, Düzgün S, Ulusan Ö, Akpek F. Effectiveness of conventional syringe irrigation, vibringe, and passive ultrasonic irrigation performed with different irrigation regimes in removing triple antibiotic paste from simulated root canal irregularities. J Conserv Dent 2016; 19: 323-7.
- 14. FKG Swiss Endo (2016) XP-endo Finisher: 3rd generation. [http://www.fkg.ch/sites/default/files/201610\_fkg\_xp\_endo\_finisher\_brochure\_v2\_en\_web.pdf](http://www.fkg.ch/sites/default/files/201610_fkg_xp_endo_finisher_brochure_v2_en_web.pdf). Accessed May 2, 2017.
- 15. Alves FR, Marceliano-Alves MF, Sousa JC, Silveira SB, Provenzano JC, Siqueira JF Jr. Removal of Root Canal Fillings in Curved Canals Using Either Reciprocating Single- or Rotary Multi-instrument Systems and a Supplementary Step with the XP-Endo Finisher. J Endod 2016; 42: 1114-9.
- 16. Bao P, Shen Y, Lin J, Haapasalo M. In Vitro Efficacy of XP-endo Finisher with 2 Different Protocols on Biofilm Removal from Apical Root Canals. J Endod 2017; 43: 321-5.
- 17. Gokturk H, Ozkocak I, Buyukgebiz F, Demir O. An in vitro evaluation of various irrigation techniques for the removal of double antibiotic paste from root canal surfaces. J Appl Oral Sci 2016; 24: 568-74.
- 18. Keskin C, Sariyilmaz E, Sariyilmaz Ö. Efficacy of XP-endo Finisher File in Removing Calcium Hydroxide from Simulated Internal Resorption Cavity. J Endod 2017; 43: 126-30.
- 19. Topçuoğlu HS, Düzgün S, Ceyhanlı KT, Aktı A, Pala K, Kesim B. Efficacy of different irrigation techniques in the removal of calcium hydroxide from a simulated internal root resorption cavity. Int Endod J 2015; 48: 309-16.
- 20. Arslan H, Akcay M, Capar ID, Ertas H, Ok E, Uysal B. Efficacy of needle irrigation, EndoActivator, and photon-initiated photoacoustic streaming technique on removal of double and triple antibiotic pastes. J Endod 2014; 40: 1439-42.
- 21. van der Sluis LW, Wu MK, Wesselink PR. The evaluation of removal of calcium hydroxide paste from an artificial standardized groove in the apical root canal using different irrigation methodologies. Int Endod J 2007; 40: 52-7.
- 22. Prather BT, Ehrlich Y, Spolnik K, Platt JA, Yassen GH. Effects of two combinations of triple antibiotic paste used in endodontic regeneration on root microhardness and chemical structure of radicular dentine. J Oral Sci 2014; 56: 245-51.
- 23. Diogenes A, Henry MA, Teixeira FB, Hargreaves KM. An update on clinical regenerative endodontics. Endod Topics 2013; 28: 2-23.
- 24. Arslan H, Capar ID, Saygili G, Uysal B, Gok T, Ertas H, et al. Efficacy of various irrigation protocols on the removal of triple antibiotic paste. Int Endod J 2014; 47: 594-9.
- 25. Ok E, Altunsoy M, Nur BG, Kalkan A. Effectiveness of different irrigation solutions on triple antibiotic paste removal from simulated immature root canal. Scanning 2015; 37: 409-13.
- 26. Tanase S, Tsuchiya H, Yao J, Ohmoto S, Takagi N, Yoshida S. Reversed-phase ion-pair chromatographic analysis of tetracycline antibiotics. Application to discolored teeth. J Chromatogr B Biomed Sci Appl 1998; 706: 279-85.
Year 2019,
Volume: 20 Issue: 2, 129 - 136, 31.08.2019
Abstract
Objective: Aim of this study was to compare the double (DAP) and triple (TAP) antibiotic paste removal efficiency of conventional syringe irrigation (CSI), EndoActivator (EA), passive ultrasonic irrigation (PUI) and XP-endo finisher (XPF) from simulated immature root canals.
Materials and Methods: A total of 180 extracted mandibular canine roots were used. The apical 2 mm of the roots were removed, and Unicore drills were penetrated through the apical to the coronal direction approximately 1 mm to simulate an immature apex. Canals were prepared up to size 40 by using the Mtwo system. Roots were split longitudinally and then temporarily reassembled. The samples were randomly divided into 2 main groups as DAP and TAP. Five specimens for each main group were kept as negative control group. Then the pastes were placed with lentulo spiral. After 1 week five specimens for each main group were kept as positive control group. Then the remaining specimens in DAP and TAP groups were further assigned to 4 subgroups according to the removal technique (group 1: CSI; group 2: EA; group 3: PUI, group 4: XPF). The root halves were examined under a stereomicroscope at 10x magnification. Kruskal-Wallis H and Mann-Whitney U tests were used for statistical analyses.
Results: TAP and DAP were more effectively removed by XPF and PUI compared to CSI and EA (p<0.05). XPF and PUI DAP/TAP removal effectiveness was statistically similar (p>0.05). Moreover, CSI and EA showed similar effectiveness for both paste groups (p>0.05). Regarding the type of antibiotic paste, no significant difference between TAP and DAP was found (p>0.05).
Conclusion: The tested irrigation systems could not completely remove either TAP or DAP. The use of PUI or the XPF was more effective compared to the use of the EA and CSI.
Keywords
Double antibiotic paste triple antibiotic paste regenerative endodontics irrigation removal efficiency
References
- 1. Cao Y, Song M, Kim E, Shon W, Chugal N, Bogen G, et al. Pulp-dentin Regeneration: Current State and Future Prospects. J Dent Res 2015; 94: 1544-51.
- 2. Jung IY, Lee SJ, Hargreaves KM. Biologically based treatment of immature permanent teeth with pulpal necrosis: a case series. J Endod 2008; 34: 876-87.
- 3. Nabeel A, Prasanna N. Antiseptics and Antibiotics Used in Regenerative Endodontics. Int J Pharm and Clin Res 2013; 5: 141-4.
- 4. Sato I, Ando-Kurihara N, Kota K, Iwaku M, Hoshino E. Sterilization of infected root-canal dentine by topical application of a mixture of ciprofloxacin, metronidazole and minocycline in situ. Int Endod J 1996; 29: 118-24.
- 5. Kim JH, Kim Y, Shin SJ, Park JW, Jung IY. Tooth discoloration of immature permanent incisor associated with triple antibiotic therapy: a case report. J Endod 2010; 36: 1086-91.
- 6. Thibodeau B, Trope M. Pulp revascularization of a necrotic infected immature permanent tooth: case report and review of the literature. Pediatr Dent 2007; 29: 47-50.
- 7. Thomson A, Kahler B. Regenerative endodontics--biologically based treatment for immature permanent teeth: a case report and review of the literature. Aust Dent J 2010; 55: 446-52.
- 8. Sato T, Hoshino E, Uematsu H, Noda T. In vitro antimicrobial susceptibility to combinations of drugs on bacteria from carious and endodontic lesions of human deciduous teeth. Oral Microbiol Immunol 1993; 8: 172-6.
- 9. Iwaya SI, Ikawa M, Kubota M. Revascularization of an immature permanent tooth with apical periodontitis and sinus tract. Dent Traumatol 2001; 17: 185-7.
- 10. Berkhoff JA, Chen PB, Teixeira FB, Diogenes A. Evaluation of triple antibiotic paste removal by different irrigation procedures. J Endod 2014; 40: 1172-7.
- 11. Ruparel NB, Teixeira FB, Ferraz CC, Diogenes A. Direct effect of intracanal medicaments on survival of stem cells of the apical papilla. J Endod 2012; 38: 1372-5.
- 12. Banchs F, Trope M. Revascularization of immature permanent teeth with apical periodontitis: new treatment protocol? J Endod 2004; 30: 196-200.
- 13. Topçuoğlu HS, Aktı A, Topçuoğlu G, Düzgün S, Ulusan Ö, Akpek F. Effectiveness of conventional syringe irrigation, vibringe, and passive ultrasonic irrigation performed with different irrigation regimes in removing triple antibiotic paste from simulated root canal irregularities. J Conserv Dent 2016; 19: 323-7.
- 14. FKG Swiss Endo (2016) XP-endo Finisher: 3rd generation. [http://www.fkg.ch/sites/default/files/201610\_fkg\_xp\_endo\_finisher\_brochure\_v2\_en\_web.pdf](http://www.fkg.ch/sites/default/files/201610_fkg_xp_endo_finisher_brochure_v2_en_web.pdf). Accessed May 2, 2017.
- 15. Alves FR, Marceliano-Alves MF, Sousa JC, Silveira SB, Provenzano JC, Siqueira JF Jr. Removal of Root Canal Fillings in Curved Canals Using Either Reciprocating Single- or Rotary Multi-instrument Systems and a Supplementary Step with the XP-Endo Finisher. J Endod 2016; 42: 1114-9.
- 16. Bao P, Shen Y, Lin J, Haapasalo M. In Vitro Efficacy of XP-endo Finisher with 2 Different Protocols on Biofilm Removal from Apical Root Canals. J Endod 2017; 43: 321-5.
- 17. Gokturk H, Ozkocak I, Buyukgebiz F, Demir O. An in vitro evaluation of various irrigation techniques for the removal of double antibiotic paste from root canal surfaces. J Appl Oral Sci 2016; 24: 568-74.
- 18. Keskin C, Sariyilmaz E, Sariyilmaz Ö. Efficacy of XP-endo Finisher File in Removing Calcium Hydroxide from Simulated Internal Resorption Cavity. J Endod 2017; 43: 126-30.
- 19. Topçuoğlu HS, Düzgün S, Ceyhanlı KT, Aktı A, Pala K, Kesim B. Efficacy of different irrigation techniques in the removal of calcium hydroxide from a simulated internal root resorption cavity. Int Endod J 2015; 48: 309-16.
- 20. Arslan H, Akcay M, Capar ID, Ertas H, Ok E, Uysal B. Efficacy of needle irrigation, EndoActivator, and photon-initiated photoacoustic streaming technique on removal of double and triple antibiotic pastes. J Endod 2014; 40: 1439-42.
- 21. van der Sluis LW, Wu MK, Wesselink PR. The evaluation of removal of calcium hydroxide paste from an artificial standardized groove in the apical root canal using different irrigation methodologies. Int Endod J 2007; 40: 52-7.
- 22. Prather BT, Ehrlich Y, Spolnik K, Platt JA, Yassen GH. Effects of two combinations of triple antibiotic paste used in endodontic regeneration on root microhardness and chemical structure of radicular dentine. J Oral Sci 2014; 56: 245-51.
- 23. Diogenes A, Henry MA, Teixeira FB, Hargreaves KM. An update on clinical regenerative endodontics. Endod Topics 2013; 28: 2-23.
- 24. Arslan H, Capar ID, Saygili G, Uysal B, Gok T, Ertas H, et al. Efficacy of various irrigation protocols on the removal of triple antibiotic paste. Int Endod J 2014; 47: 594-9.
- 25. Ok E, Altunsoy M, Nur BG, Kalkan A. Effectiveness of different irrigation solutions on triple antibiotic paste removal from simulated immature root canal. Scanning 2015; 37: 409-13.
- 26. Tanase S, Tsuchiya H, Yao J, Ohmoto S, Takagi N, Yoshida S. Reversed-phase ion-pair chromatographic analysis of tetracycline antibiotics. Application to discolored teeth. J Chromatogr B Biomed Sci Appl 1998; 706: 279-85.
There are 26 citations in total.
Details
| Primary Language | English |
|---|---|
| Subjects | Dentistry (Other) |
| Journal Section | Research Article |
| Authors | |
| Publication Date | August 31, 2019 |
| Published in Issue | Year 2019 Volume: 20 Issue: 2 |