Letter to Editor for The Diagnostic Value of Neutrophil/Lymphocyte Ratio in Distinguishing Peripheral and Central Vertigo in Patients with Dizziness
Abstract
The study titled "Diagnostic Value of Neutrophil/Lymphocyte Ratio in Distinguishing Peripheral and Central Vertigo in Patients with Dizziness" explores the utility of the neutrophil-to-lymphocyte ratio (NLR) as a diagnostic marker for differentiating central and peripheral vertigo. Findings reveal that NLR is significantly higher in central vertigo cases (median: 3.99 vs. 2.32; p<0.001), with a proposed cut-off value of 3.25. The retrospective study, involving 260 patients, highlights NLR's potential as a cost-effective, rapid diagnostic tool in emergency settings. However, its retrospective design and the need for validation across diverse populations suggest the necessity for further prospective research to confirm diagnostic accuracy and explore underlying mechanisms.
References
- Sertbaş İ, Çiçek M, Yadigaroğlu M, et al. Diagnostic Value of Neutrophil/Lymphocyte Ratio in Distinguishing Peripheral and Central Vertigo in Patients with Dizziness. Online Turkish Journal of Health Sciences. 2024;9(3):240-245. doi:10.26453/otjhs.1461279
- Lee SH, Yun SJ, Ryu S, et al. Utility of neutrophil-to-lymphocyte ratio (NLR) as a predictor of acute infarction in new-onset acute vertigo patients without neurologic and computed tomography abnormalities. J Emerg Med. 2018;54:607-614.
- Celikbilek A, Ismailogullari S, Zararsiz G. Neutrophil to lymphocyte ratio predicts poor prognosis in ischemic cerebrovascular disease. J Clin Lab Anal. 2014;28:27-31.
- Vural N, Duyan M, Saridas A, et al. The Predictive Value of Inflammatory Biomarkers in Distinguishing Testicular Torsion and Epididymo-Orchitis in the Emergency Department. Mev Med Sci. 2024;4(3):113-118.
- Duyan M, Saridas A, Vural N. Predictors of In-hospital Death in Patients with Stanford Type B Acute Aortic Dissection. Eurasian Journal of Critical Care. 2022;4(3):96-100. doi:10.55994/gcc.1193021
- Vural N, Duyan M, Saridas A, et al. Evaluation of Inflammatory Biomarkers in Predicting Strangulation in Incarcerated Inguinal Hernias. Med J West Black Sea. 2024;8(3):276-282. doi:10.29058/mjwbs.1465537
- Vural N, Duyan M, Saridas A, et al. The Predictive Value of Inflammatory Biomarkers in the Detection of Multiple Sclerosis Attacks. Emergency Care Journal. 2023;19:11314. doi:10.4081/ecj.2023.11314
- Saridas A, Vural N, Duyan M, et al. Comparison of the Ability of Newly Inflammatory Markers to Predict Complicated Appendicitis. Open Medicine. 2024;19:20241002. doi:10.1515/med-2024-1002
- Tokgoz S, Kayrak M, Akpinar Z, et al. Neutrophil lymphocyte ratio as a predictor of stroke. J Stroke Cerebrovasc Dis. 2013;22:1169-1174.
- Wang F, Hu S, Ding Y, et al. Neutrophil-to-lymphocyte ratio and 30-day mortality in patients with acute intracerebral hemorrhage. J Stroke Cerebrovasc Dis. 2016;25:182-187.
Editöre Mektup: Baş Dönmesi Olan Hastalarda Periferik ve Santral Vertigonun Ayırt Edilmesinde Nötrofil/Lenfosit Oranının Tanısal Değeri
Abstract
Baş Dönmesi Olan Hastalarda Periferik ve Santral Vertigonun Ayırt Edilmesinde Nötrofil/Lenfosit Oranının Tanı Değeri" başlıklı çalışma, nötrofil-lenfosit oranının (NLR) santral ve periferik vertigoyu ayırt etmede tanısal bir belirteç olarak kullanılabilirliğini araştırıyor. Bulgular, santral vertigo vakalarında NLR'nin anlamlı derecede daha yüksek olduğunu (medyan: 3,99 vs. 2,32; p<0,001) ve 3,25'lik bir eşik değer önerildiğini gösteriyor. Retrospektif bir çalışma olan bu araştırma, 260 hastayı kapsıyor ve NLR'nin acil durumlarda hızlı, ucuz bir tanı aracı olarak potansiyelini vurguluyor. Ancak, retrospektif tasarımı ve farklı popülasyonlarda doğrulanma ihtiyacı, tanısal doğruluğun teyit edilmesi ve altta yatan mekanizmaların araştırılması için ileri prospektif çalışmaların gerekliliğine işaret ediyor.
References
- Sertbaş İ, Çiçek M, Yadigaroğlu M, et al. Diagnostic Value of Neutrophil/Lymphocyte Ratio in Distinguishing Peripheral and Central Vertigo in Patients with Dizziness. Online Turkish Journal of Health Sciences. 2024;9(3):240-245. doi:10.26453/otjhs.1461279
- Lee SH, Yun SJ, Ryu S, et al. Utility of neutrophil-to-lymphocyte ratio (NLR) as a predictor of acute infarction in new-onset acute vertigo patients without neurologic and computed tomography abnormalities. J Emerg Med. 2018;54:607-614.
- Celikbilek A, Ismailogullari S, Zararsiz G. Neutrophil to lymphocyte ratio predicts poor prognosis in ischemic cerebrovascular disease. J Clin Lab Anal. 2014;28:27-31.
- Vural N, Duyan M, Saridas A, et al. The Predictive Value of Inflammatory Biomarkers in Distinguishing Testicular Torsion and Epididymo-Orchitis in the Emergency Department. Mev Med Sci. 2024;4(3):113-118.
- Duyan M, Saridas A, Vural N. Predictors of In-hospital Death in Patients with Stanford Type B Acute Aortic Dissection. Eurasian Journal of Critical Care. 2022;4(3):96-100. doi:10.55994/gcc.1193021
- Vural N, Duyan M, Saridas A, et al. Evaluation of Inflammatory Biomarkers in Predicting Strangulation in Incarcerated Inguinal Hernias. Med J West Black Sea. 2024;8(3):276-282. doi:10.29058/mjwbs.1465537
- Vural N, Duyan M, Saridas A, et al. The Predictive Value of Inflammatory Biomarkers in the Detection of Multiple Sclerosis Attacks. Emergency Care Journal. 2023;19:11314. doi:10.4081/ecj.2023.11314
- Saridas A, Vural N, Duyan M, et al. Comparison of the Ability of Newly Inflammatory Markers to Predict Complicated Appendicitis. Open Medicine. 2024;19:20241002. doi:10.1515/med-2024-1002
- Tokgoz S, Kayrak M, Akpinar Z, et al. Neutrophil lymphocyte ratio as a predictor of stroke. J Stroke Cerebrovasc Dis. 2013;22:1169-1174.
- Wang F, Hu S, Ding Y, et al. Neutrophil-to-lymphocyte ratio and 30-day mortality in patients with acute intracerebral hemorrhage. J Stroke Cerebrovasc Dis. 2016;25:182-187.
Details
| Primary Language | English |
|---|---|
| Subjects | Emergency Medicine |
| Journal Section | Letter to the Editor |
| Authors | |
| Early Pub Date | June 24, 2025 |
| Publication Date | June 30, 2025 |
| Submission Date | March 12, 2025 |
| Acceptance Date | April 21, 2025 |
| Published in Issue | Year 2025 Volume: 10 Issue: 2 |
