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Use of Sesame Oil in Pain Management: Literature Review

Year 2025, Volume: 8 Issue: 1, 23 - 27, 30.04.2025

Müzeyyen Ataseven , Nuray Şahin Orak

https://doi.org/10.56150/tjhsl.1263259

Abstract

Despite the developments in the health field, pain is still seen as a universal problem worldwide. Effective pain management is essential in shortening the recovery period of the individual, reducing treatment costs, preventing the formation of chronic pain, and increasing the quality of life. In current guidelines, it is mentioned that non-pharmacological methods can be used in addition to pharmacological treatment in pain management. Today, it is known that aromatherapy has an important place among complementary and holistic therapy methods. It is stated that sesame oil, which is one of the aromatherapy oils, has essential effects such as antioxidant, anti-inflammatory and antibacterial. However, it has been emphasized that the evidence on the clinical effectiveness of non-pharmacological interventions in pain management is insufficient in current pain guidelines and that further studies using a combination of pharmacological and non-pharmacological methods are needed. In this context, there is a need to increase studies that can provide evidence to evaluate the applicability of sesame oil, which is one of the aromatherapy oils, in addition to pharmacological treatment in interventions for pain management.

Keywords

Pain sesame oil aromatherapy non-pharmacologic technic

References

  • International Association for the Study of Pain, I. Classification of chronic pain: introduction. Pain 1986; 24: 3-8.
  • Aslan FE, Yıldız T (2017). Ağrı ve Ağrı Yönetimi. 109-136. In: Aslan FE, Olgun N. eds. Fizyopatoloji, 1. Baskı. Ankara: Akademisyen Tıp kitapevi.
  • Yücel A. Ağrı mekanizmaları (2014). P: 42. In: Aslan FE ed. Ağrı Doğası ve Kontrolü. 2. Baskı. Ankara: Akademisyen Tıp Kitapevi.
  • Eti Aslan F, Badir A. Reality about pain control: the knowledge and beliefs of nurses on the nature, assessment, and management of pain. Agri 2005;17(2):44–51.
  • Tel, H. (2010). Ağrı, ağrıya yönelik uygulamalar ve hasta bakımı. 651-674. In: Klinik Beceriler, Sağlığın Değerlendirilmesi, Hasta Bakımı ve Takibi. N. Sabuncu, F. Akça Ay (Ed), Nobel Tıp Kitabevi, İstanbul
  • Acar K, Acar H, Demir F, Aslan EF. Cerrahi Sonrası Ağrı İnsidansı ve Analjezik Kullanım Miktarının Belirlenmesi. ACU Sağlık Bil Derg. 2016; (2): 85-91.
  • Reisli R, Akkaya TÖ, Arıcan Ş, Can SÖ, Çetin H, Güleç SM, Talu KG. Akut postoperatif ağrının farmakolojik tedavisi: Türk Algoloji- Ağrı Derneği Klinik uygulama Klavuzu. Agri. 2021; 33(1): 1-5.
  • Lee B, Schung SA, Joshi GP Kehlet H; PROSPECT Working Group. Procedure Specific Pain Management (PROSPECT)- An update. Best Pract Res Clin Anaesthesiol. 2018; 32(2): 101-111.
  • Small C. Laycock H. Acute postoperative pain management. BJS. 2020; 107: 70-80.
  • Lee B, Schung SA, Joshi GP Kehlet H; PROSPECT Working Group. Procedure Specific Pain Management (PROSPECT)- An update. Best Pract Res Clin Anaesthesiol. 2018; 32 (2): 101-111.
  • Chou R, Gordon DB, De Leon-Casasola OA, Rosenberg JM, Bickler S, Brennan T, Carter T, Cassidy CL, Chittenden EH, Degenhardt E, Griffith S, Manworren R, McCarberg B, Montgomery R, Murphy J, Perkal MF, Suresh S, Sluka K, Strassels S, Wu CL. Management of postoperative pain: A clinical practice guideline from the American Pain Society, the American Society of Regional Anesthesia and Pain Medicine, and the American Society of Anesthesiologists’ Committee on regional anesthesia, executive commit. Journal of Pain. 2016; 17(2):131–157.
  • Maltepe F (2019). Non-steroid antiinflamatuvar ilaçlar ve postoperatif ağrı tedavisi. 69-72. In: Erkin Y, Özkardeşler S, eds. Postoperatif ağrı tedavisi. 1. Baskı. İstanbul: İstanbul tıp kitapevi.
  • Şenyüz KY, Koçaşlı S. Cerrahi sonrası ağrıda multimodal analjezi ve hemşirelik yaklaşımı. Sağ Aka Derg. 2017; 4(2): 90-95.
  • Gültekin E. Ethical issues in aromatherapy courses in Turkey. Turkiye Klin J. Med. Ethics-Law Hist. 2020; 28: 273-278.
  • Yazıcıoğlu A, Bingöl BH. Antimikrobiyal olarak kullanılan bazı uçucu yağların antiviral özellikleri ve aromaterapi uygulamaları. Geleneksel ve Tamamlayıcı Tıp Dergisi. 2021; 4(1): 98-108.
  • Bilgiç, Ş. Hemşirelikte Holistik Bir Uygulama; Aromaterapi. Namık Kemal Tıp Dergisi. 2017; 5 (3): 134-141.
  • Özata N (2019). Fitoterapi ve Aromaterapi. 1-5. III. Baskı, İstanbul: İstanbul Medikal Sağlık ve Yayıncılık.
  • Kartal M, Demirbolat İ (2021). Avrupa Farmakopesinde bulunan sabit yağlar ve aromaterapide kullanımları. 43-52. Altıntaş A, Kartal M, eds. Aromaterapi. 1. Baskı. Ankara: Türkiye Klinikleri.
  • Nasiri M, Farsi Z. Effect of light pressure stroking massage with sesame (Sesamum indicum L.) oil on alleviating acute traumatic limbs pain: A triple-blind controlled trial in the emergency department. Complementary Therapies in Medicine. 2017, 32: 41-48.
  • Singletary KW. Sesame, Potential Health benefits. Nutrition Today. 2022; 5 (57): 271-287.
  • Gholami M, Davan TS, Gholami M, Bolandparvaz S, Gholami M, Chamanpara P, Shayan L. Effects of Topical Sesame Oil Extracted from Tahini (Ardeh) on Pain Severity in Trauma Patients: A Randomized Double-Blinded Placebo-Controlled Clinical Trial. Bull Emerg Trauma. 2020; 8 (3):179-185.
  • Andargie M, Vinas M, Rathgeb A, et al. Lignans of sesame (Sesamum indicum L.): A comprehensive review. Molecules. 2021; 26:883.
  • Bigdeli Shamlooa MB, Nasiri M, Dabirian A, Bakhtiyari A, Mojab F, Majd HA. The effect of Topical Sesame oil on pain severity and amount of received non-steroid anti-inflammatory drugs in patients with upper or lower extremities trauma. Anesth Pain Med. 2015 June; 5(3): e25085.
  • Nekuzad N, Ashke Torab T, Mojab F, Alavi-Majd H, Azadeh P, Ehtejab G. Effect of external use of sesame oil in the prevention of chemotherapy-induced phlebitis, Iran. J. Pharm. Res. 2012;11 (4): 1065–1071.
  • Mosayebi N, Shafipor SZ, Asgari F, Atrkarroushan Z, Pasdaran A. The Efficacy and Safety of Sesame Oil in Prevention of Chemotherapy-Induced Phlebitis in Children with Acute Lymphoblastic Leukemia. Iran J Ped Hematol Oncol. 2017; 7 (4): 198-206.
  • Eftekhar Sadat B, Khadem Haghighian M, Alipoor B, Malek Mahdavi A, Asghari Jafarabadi M, Moghaddam A. Effects of sesame seed supplementation on clinical signs and symptoms in patients with knee osteoarthritis. Int J Rheum Dis. 2013;16(5):578-82.
  • Asgari M, Alavi A, Dashtinezhad E. The effect of back massage with sesame oil on pain and length of delivery in primiparous women. Iran J Obstet Gynecol Infertil 2016; 18:12- 19.
  • Ebolfazli M, Jalalinia SF, Khadem E, Haghani H, Varaei S. A Comparative Study of Chamomile Oil and Sesame Oil on Chronic Low Back Pain: A Randomized, Double-Blinded, Controlled Clinical Trial. Trad Integr Med 2021; 6(3): 174-183.
  • Ang ES, Lee ST, Gan CS, See PG, Chan YH, Ng LH, et al. Evaluating the role of alternative therapy in burn wound management: a randomized trial comparing moist exposed burn ointment with conventional methods in the management of patients with second-degree burns. MedGenMed. 2001;3(2):3.
  • Saleem TM, Basha SD, Mahesh G, Rani PS, Kumar NS, Chetty CM. The analgesic, antipyretic, and anti-inflammatory activity of dietary sesame oil in experimental animal models. Pharmacologia 2011;2(6):172-7.
  • Monteiro ÉMH, Chibli LA, Yamamoto CH, Pereira MCS, Vilela FMP, Rodarte MP, et al. Antinociceptive and anti-inflammatory activities of the sesame oil and sesamin. Nutrients. 2014; 6(5):1931-44.
  • Wan Y, Yang YJ, Li YS, Li XJ, Zhang W, Liu M, Tang HB. Effects of San-Huang-sheng-fu oil on peripheral circulatory disorders and foot ulcers in diabetic rats and the mechanisms. Zhonghua Shao Shang Za Zhi. 2016; 32(3):168-75
  • Hsu DZ, Chu PY, Jou IM. Daily sesame oil supplement attenuates joint pain by inhibiting muscular oxidative stress in the osteoarthritis rat model. J Nutr Biochem. 2016; 29:36-40.
  • Hsu DZ, Chu PY, Jou IM. Enteral sesame oil therapeutically relieves disease severity in rat experimental osteoarthritis. Food Nutr Res. 2016; 60: 29807.

Year 2025, Volume: 8 Issue: 1, 23 - 27, 30.04.2025

Müzeyyen Ataseven , Nuray Şahin Orak

https://doi.org/10.56150/tjhsl.1263259

Abstract

References

  • International Association for the Study of Pain, I. Classification of chronic pain: introduction. Pain 1986; 24: 3-8.
  • Aslan FE, Yıldız T (2017). Ağrı ve Ağrı Yönetimi. 109-136. In: Aslan FE, Olgun N. eds. Fizyopatoloji, 1. Baskı. Ankara: Akademisyen Tıp kitapevi.
  • Yücel A. Ağrı mekanizmaları (2014). P: 42. In: Aslan FE ed. Ağrı Doğası ve Kontrolü. 2. Baskı. Ankara: Akademisyen Tıp Kitapevi.
  • Eti Aslan F, Badir A. Reality about pain control: the knowledge and beliefs of nurses on the nature, assessment, and management of pain. Agri 2005;17(2):44–51.
  • Tel, H. (2010). Ağrı, ağrıya yönelik uygulamalar ve hasta bakımı. 651-674. In: Klinik Beceriler, Sağlığın Değerlendirilmesi, Hasta Bakımı ve Takibi. N. Sabuncu, F. Akça Ay (Ed), Nobel Tıp Kitabevi, İstanbul
  • Acar K, Acar H, Demir F, Aslan EF. Cerrahi Sonrası Ağrı İnsidansı ve Analjezik Kullanım Miktarının Belirlenmesi. ACU Sağlık Bil Derg. 2016; (2): 85-91.
  • Reisli R, Akkaya TÖ, Arıcan Ş, Can SÖ, Çetin H, Güleç SM, Talu KG. Akut postoperatif ağrının farmakolojik tedavisi: Türk Algoloji- Ağrı Derneği Klinik uygulama Klavuzu. Agri. 2021; 33(1): 1-5.
  • Lee B, Schung SA, Joshi GP Kehlet H; PROSPECT Working Group. Procedure Specific Pain Management (PROSPECT)- An update. Best Pract Res Clin Anaesthesiol. 2018; 32(2): 101-111.
  • Small C. Laycock H. Acute postoperative pain management. BJS. 2020; 107: 70-80.
  • Lee B, Schung SA, Joshi GP Kehlet H; PROSPECT Working Group. Procedure Specific Pain Management (PROSPECT)- An update. Best Pract Res Clin Anaesthesiol. 2018; 32 (2): 101-111.
  • Chou R, Gordon DB, De Leon-Casasola OA, Rosenberg JM, Bickler S, Brennan T, Carter T, Cassidy CL, Chittenden EH, Degenhardt E, Griffith S, Manworren R, McCarberg B, Montgomery R, Murphy J, Perkal MF, Suresh S, Sluka K, Strassels S, Wu CL. Management of postoperative pain: A clinical practice guideline from the American Pain Society, the American Society of Regional Anesthesia and Pain Medicine, and the American Society of Anesthesiologists’ Committee on regional anesthesia, executive commit. Journal of Pain. 2016; 17(2):131–157.
  • Maltepe F (2019). Non-steroid antiinflamatuvar ilaçlar ve postoperatif ağrı tedavisi. 69-72. In: Erkin Y, Özkardeşler S, eds. Postoperatif ağrı tedavisi. 1. Baskı. İstanbul: İstanbul tıp kitapevi.
  • Şenyüz KY, Koçaşlı S. Cerrahi sonrası ağrıda multimodal analjezi ve hemşirelik yaklaşımı. Sağ Aka Derg. 2017; 4(2): 90-95.
  • Gültekin E. Ethical issues in aromatherapy courses in Turkey. Turkiye Klin J. Med. Ethics-Law Hist. 2020; 28: 273-278.
  • Yazıcıoğlu A, Bingöl BH. Antimikrobiyal olarak kullanılan bazı uçucu yağların antiviral özellikleri ve aromaterapi uygulamaları. Geleneksel ve Tamamlayıcı Tıp Dergisi. 2021; 4(1): 98-108.
  • Bilgiç, Ş. Hemşirelikte Holistik Bir Uygulama; Aromaterapi. Namık Kemal Tıp Dergisi. 2017; 5 (3): 134-141.
  • Özata N (2019). Fitoterapi ve Aromaterapi. 1-5. III. Baskı, İstanbul: İstanbul Medikal Sağlık ve Yayıncılık.
  • Kartal M, Demirbolat İ (2021). Avrupa Farmakopesinde bulunan sabit yağlar ve aromaterapide kullanımları. 43-52. Altıntaş A, Kartal M, eds. Aromaterapi. 1. Baskı. Ankara: Türkiye Klinikleri.
  • Nasiri M, Farsi Z. Effect of light pressure stroking massage with sesame (Sesamum indicum L.) oil on alleviating acute traumatic limbs pain: A triple-blind controlled trial in the emergency department. Complementary Therapies in Medicine. 2017, 32: 41-48.
  • Singletary KW. Sesame, Potential Health benefits. Nutrition Today. 2022; 5 (57): 271-287.
  • Gholami M, Davan TS, Gholami M, Bolandparvaz S, Gholami M, Chamanpara P, Shayan L. Effects of Topical Sesame Oil Extracted from Tahini (Ardeh) on Pain Severity in Trauma Patients: A Randomized Double-Blinded Placebo-Controlled Clinical Trial. Bull Emerg Trauma. 2020; 8 (3):179-185.
  • Andargie M, Vinas M, Rathgeb A, et al. Lignans of sesame (Sesamum indicum L.): A comprehensive review. Molecules. 2021; 26:883.
  • Bigdeli Shamlooa MB, Nasiri M, Dabirian A, Bakhtiyari A, Mojab F, Majd HA. The effect of Topical Sesame oil on pain severity and amount of received non-steroid anti-inflammatory drugs in patients with upper or lower extremities trauma. Anesth Pain Med. 2015 June; 5(3): e25085.
  • Nekuzad N, Ashke Torab T, Mojab F, Alavi-Majd H, Azadeh P, Ehtejab G. Effect of external use of sesame oil in the prevention of chemotherapy-induced phlebitis, Iran. J. Pharm. Res. 2012;11 (4): 1065–1071.
  • Mosayebi N, Shafipor SZ, Asgari F, Atrkarroushan Z, Pasdaran A. The Efficacy and Safety of Sesame Oil in Prevention of Chemotherapy-Induced Phlebitis in Children with Acute Lymphoblastic Leukemia. Iran J Ped Hematol Oncol. 2017; 7 (4): 198-206.
  • Eftekhar Sadat B, Khadem Haghighian M, Alipoor B, Malek Mahdavi A, Asghari Jafarabadi M, Moghaddam A. Effects of sesame seed supplementation on clinical signs and symptoms in patients with knee osteoarthritis. Int J Rheum Dis. 2013;16(5):578-82.
  • Asgari M, Alavi A, Dashtinezhad E. The effect of back massage with sesame oil on pain and length of delivery in primiparous women. Iran J Obstet Gynecol Infertil 2016; 18:12- 19.
  • Ebolfazli M, Jalalinia SF, Khadem E, Haghani H, Varaei S. A Comparative Study of Chamomile Oil and Sesame Oil on Chronic Low Back Pain: A Randomized, Double-Blinded, Controlled Clinical Trial. Trad Integr Med 2021; 6(3): 174-183.
  • Ang ES, Lee ST, Gan CS, See PG, Chan YH, Ng LH, et al. Evaluating the role of alternative therapy in burn wound management: a randomized trial comparing moist exposed burn ointment with conventional methods in the management of patients with second-degree burns. MedGenMed. 2001;3(2):3.
  • Saleem TM, Basha SD, Mahesh G, Rani PS, Kumar NS, Chetty CM. The analgesic, antipyretic, and anti-inflammatory activity of dietary sesame oil in experimental animal models. Pharmacologia 2011;2(6):172-7.
  • Monteiro ÉMH, Chibli LA, Yamamoto CH, Pereira MCS, Vilela FMP, Rodarte MP, et al. Antinociceptive and anti-inflammatory activities of the sesame oil and sesamin. Nutrients. 2014; 6(5):1931-44.
  • Wan Y, Yang YJ, Li YS, Li XJ, Zhang W, Liu M, Tang HB. Effects of San-Huang-sheng-fu oil on peripheral circulatory disorders and foot ulcers in diabetic rats and the mechanisms. Zhonghua Shao Shang Za Zhi. 2016; 32(3):168-75
  • Hsu DZ, Chu PY, Jou IM. Daily sesame oil supplement attenuates joint pain by inhibiting muscular oxidative stress in the osteoarthritis rat model. J Nutr Biochem. 2016; 29:36-40.
  • Hsu DZ, Chu PY, Jou IM. Enteral sesame oil therapeutically relieves disease severity in rat experimental osteoarthritis. Food Nutr Res. 2016; 60: 29807.
There are 34 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Articles
Authors

Müzeyyen Ataseven 0000-0003-0370-0937

Nuray Şahin Orak 0000-0002-9356-2971

Publication Date April 30, 2025
Published in Issue Year 2025 Volume: 8 Issue: 1

Cite

APA Ataseven, M., & Şahin Orak, N. (2025). Use of Sesame Oil in Pain Management: Literature Review. Turkish Journal of Health Science and Life, 8(1), 23-27. https://doi.org/10.56150/tjhsl.1263259
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