Research Article
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Year 2025, Volume: 6 Issue: 1, 59 - 73, 30.06.2025

Belgin Erdem , İlkay Açıkgöz Erkaya , Dilek Yalçın

https://doi.org/10.46592/turkager.1680203

Abstract

Project Number

Project No: SAG.A4.21.002

References

  • Abudoleh SM and Mahasneh AM (2017). Anti-quorum sensing activity of substances isolated from wild berry associated bacteria. Avicenna Journal of Medical Biotechnology, 9(1): 23-30.
  • Abdollahzadeh R, Pazhang M, Najavand S, Fallahzadeh-Mamaghani V, Amani-Ghadim AR (2020). Screening of pectinase-producing bacteria from farmlands and optimization of enzyme production from selected strain by RSM. Folia Microbiol, 65: 705-719. https://doi.org/10.1007/s12223-020-00776-7
  • Alam K, Farraj DAA, Mah-E-Fatima S, Yameen MA, Elshikh MS, Alkufeidy RM, Mustafa AEMA, Bhasme P, Alshammari MK, Alkubaisi NA, Abbasi AM and Naqvi TA (2020). Anti-biofilm activity of plant derived extracts against infectious pathogen-Pseudomonas aeruginosa PAO1. Journal of Infection and Public Health, 13(11): 1734-1741.
  • Alatoom AA, Cunningham SA, Ihde S M, Mandrekar J and Patel R (2011). Comparison of Direct Colony Method Versus Extraction Method for Identification of Gram-Positive Cocci by Use of Bruker Biotyper Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry. Journal of Clinical Microbiology, 49(8): 2868–2873. https://doi.org/10.1128/JCM.00506-11
  • Asfour HZ (2018). Anti-Quorum sensing natural compounds. Journal of Microscopy and Ultrastructure, 6(1): 1-10.
  • Basavaraju M, Sisnity VS, Palaparthy R and Addanki PK (2016). Quorum quenching: Signal jamming in dental plaque biofilms. Journal of Dental Sciences, 11(4): 349-352.
  • Bhardwaj AK, Vinothkumar K and Rajpara N (2013). Bacterial quorum sensing inhibitors: Attractive alternatives for control of infectious pathogens showing multiple drug resistance. Recent Patents on Anti-Infective Drug Discovery, 8(1): 68-83.
  • Biradar B and Devi P (2011). Quorum sensing in plaque biofilms: challenges and future prospects. Journal of Contemporary Dental Practice, 12(6): 479-485. https://doi.org/10.5005/jp-journals-10024-1080
  • Bizzini A, Durussel C, Bille J, Greub G and Prod'hom G (2010). Performance of matrix-assisted laser desorption ionization-time of flight mass spectrometry for identification of bacterial strains routinely isolated in a clinical microbiology laboratory. Journal of Clinical Microbiology, 48(5): 1549-1554. https://doi.org/10.1128/JCM.01794-09
  • Brackman G, Cos P, Maes L, Nelis H and Coenye T (2011). Quorum sensing inhibitors increase the susceptibility of bacterial biofilms to antibiotics in vitro and in vivo. Antimicrobial Agents and Chemotherapy, 55 (6): 2655-61. https://doi.org/10.1128/AAC.00045-11
  • Cegelski L, Marshall GR, Eldridge GR and Hultgren SJ (2008). The biology and future prospects of antivirulence therapies. Nat Rev Microbiol, 6 (1): 17-27. https://doi.org/10.1038/nrmicro1818.
  • Chikere CB and Udochukwu U (2014) Effect of growth media and incubation time on the culturability of soil bacteria. IOSR Journal of Pharmacy and Biological Sciences, 9(2):6-9. https://doi.org/10.9790/3008-09210609
  • Choo JH, Rukayadi Y and Hwang JK (2006). Inhibition of bacterial quorum sensing by vanilla extract. Letters in Applied Microbiology, 42(6): 637-641. https://doi.org/10.1111/j.1472-765X.2006.01928.x
  • Dadi NCT, Radochová B, Vargová J and Bujdáková H (2021). Impact of Healthcare-Associated Infections Connected to Medical Devices-An Update. Microorganisms, 9 (11): 2332. https://doi.org/10.3390/microorganisms9112332
  • Devi KR, Srinivasan S and Ravi AV (2018). Inhibition of quorum sensing-mediated virulence in Serratia marcescens by Bacillus subtilis R-18. Microbial Pathogenesis, 120: 166-175. https://doi.org/10.1016/j.micpath.2018.04.023
  • Donlan, RM (2002). Biofilms: Microbial Life on Surfaces. Emerging Infectious Diseases, 8(9): 881-890. https://doi.org/10.3201/eid0809.020063
  • Fleming D and Rumbaugh KP (2017). Approaches to dispersing medical biofilms. Microorganisms, 5(2): 15. https://doi.org/10.3390/microorganisms5020015
  • Grandclement C, Tannieres M, Morera S, Dessaux Y and Faure D (2016). Quorum quenching: role in nature and applied developments. FEMS Microbiology Reviews, 40(1): 86–116. https://doi.org/10.1093/femsre/fuv038
  • Gunn JS, Bakaletz LO and Wozniak DJ (2016). What’s on the outside matters: the role of the extracellular polymeric substance of Gram-negative biofilms in evading host immunity and as a target for therapeutic intervention. Journal of Biological Chemistry, 291(24): 12538-12546. https://doi.org/10.1074/jbc.R115.707547
  • Ghosh S, Bornman C and Zafer MM (2021). Antimicrobial resistance threats in the emerging COVID-19 pandemic: Where do we stand? Journal of Infection and Public Health, 14(5): 555-560. https://doi.org/10.1016/j.jiph.2021.02.011
  • Høiby N, Bjarnsholt T, Givskov M, Molin S and Ciofu O (2010.) Antibiotic resistance of bacterial biofilms. International Journal of Antimicrobial Agents, 35 (4): 222–332. https://doi.org/10.1016/j.ijantimicag.2009.12.011
  • Hughes G and Webber MA (2017). Novel approaches to the treatment of bacterial biofilm infections. British Journal of Pharmacology, 174(14): 2237-2246. https://doi.org/10.1111/bph.13706
  • Hunter PJ, Hand P, Pink D, Whipps JM and Bending GD (2010). Both leaf properties and microbe–microbe interactions influence within-species variation in bacterial population diversity and structure in the lettuce (Lactuca species) phyllosphere. Applied and Environmental Microbiology, 76(24): 8117–8125. https://doi.org/10.1128/AEM.01321-10
  • Kanagasabhapthy M, Yamazaki G, Ishida A, Sasaki H and Nagata S (2009). Presence of quorum-sensing inhibitors-like compounds from bacteria isolated from the brown alga Colpomenia sinusoa. Letters in Applied Microbiology, 49(5): 573-579. https://doi.org/10.1111/j.1472-765x.2009.02712.x
  • Khan MS, Zahin M, Hasan S, Husain F, and Ahmad I (2009). Inhibition of quorum sensing regulated bacterial functions by plant essential oils with special reference to clove oil. Letters in Applied Microbiology, 49(3): 354-360. https://doi.org/10.1111/j.1472-765X.2009.02666.x
  • Khan J, Tarar SM, Gul I, Nawaz U and Arshad M (2021). Challenges of antibiotic resistance biofilms and potential combating strategies: a review. 3 Biotech, 11(4): 169. https://doi.org/10.1007/s13205-021-02707-w
  • Kim EK, Jang, WH, Ko JH, Kang JS, Noh, MJ and Yoo OJ (2001). Lipase and its modulator from Pseudomonas sp. strain KFCC 10818: Proline-to-glutamine substitution at position 112 induces formation of enzymatically active lipase in the absence of the modulator. Journal of Bacteriology, 183(20): 5937-41. https://doi.org/10.1128/JB.183.20.5937-5941.2001
  • Leme AFP, Koo H, Bellato CM, Bedi G and Cury JA (2006). The Role of Sucrose in Cariogenic Dental Biofilm Formation-New. Insight. Journal of Dental Research, 85(10): 878-887. https://doi.org/10.1177/154405910608501002
  • Lobritz MA, Belenky P, Porter CB, Gutierrez A, Yang JH, Schwarz EG, Dwyer DJ, Khalil AS and Collins JJ (2015). Antibiotic efficacy is linked to bacterial cellular respiration. Proceedings of the National Academy of Sciences of the United States of America, 112,(27): 8173-8180. https://doi.org/10.1073/pnas.1509743112
  • Lokegaonkar SP and Nabar BM (2017). In Vitro Antibiofilm, Antiquorum Sensing Activity of Gamma Tolerant Streptomyces Against Gram Negative Pathogens. International Journal of Pharmacology and Clinical Research, 9 (11): 665-670.
  • Ma A, Lv D, Zhuang X and Zhuang G (2013). Quorum quenching in culturable phyllosphere bacteria from tobacco. International Journal of Molecular Sciences, 14(7): 14607–14619. https://doi.org/10.3390/ijms140714607
  • Maeda T, García-Contreras R, Pu M, Sheng L, Garcia LR, Tomás M and Wood TK (2012). Quorum quenching quandary: resistance to antivirulence compounds. ISME Journal 6, 493-501. https://doi.org/10.1038/ismej.2011.122
  • Miller MB and Bassler BL (2001). Quorum sensing in bacteria. Annual Review of Microbiology, 55: 165-199. https://doi.org/10.1146/annurev.micro.55.1.165
  • Nadell C, Xavier J, Levin S and Foster K (2008). The evolution of quorum sensing in bacterial biofilms. PLOS Biology, 6 (1):171– 179. https://doi.org/10.1371/journal.pbio.0060014
  • Nithya C, Begum MF and Pandian SK (2010a). Marine bacterial isolates inhibit biofilm formation and disrupt mature biofilms of Pseudomonas aeruginosa PAO1. Applied Microbiology and Biotechnology, 88(1): 341-358. https://doi.org/10.1007/s00253-010-2777-y
  • Nithya C, Aravindraja C and Pandian SK (2010b). Bacillus pumilus of Palk Bay origin inhibits quorum-sensing-mediated virulence factors in Gram-negative bacteria. Research in Microbiology, 161(4): 293-304. https://doi.org/10.1016/j.resmic.2010.03.002
  • Packiavathy IA, Agilandeswari P, Mustafa KS, Pandian SK and Ravi AV (2012). Antibiofilm and quorum sensing inhibitory potential of Cuminum cyminum and its secondary metabolite methyl eugenol against Gram negative bacterial pathogens. Food Research International, 45(1): 85-92. https://doi.org/10.1016/j.foodres.2011.10.022
  • Rajput M and Bithel N (2022). Phytochemical characterization and evaluation of antioxidant, antimicrobial, antibiofilm and anticancer activities of ethyl acetate seed extract of Hydnocarpus laurifolia (Dennst) Sleummer. 3 Biotech ,12(9): 215. https://doi.org/10.1007/s13205-022-03267-3
  • Relucenti M, Familiari G, Donfrancesco O, Taurino M, Li X, Chen R, Artini M, Papa R and Selan L (2021). Microscopy Methods for Biofilm Imaging: Focus on SEM and VP-SEM Pros and Cons. Biology (Basel). 12;10 (1):51. https://doi.org/1010.3390/biology10010051
  • Roy R, Tiwari M, Donelli G and Tiwari V (2018). Strategies for combating bacterial biofilms: a focus on anti-biofilm agents and their mechanisms of action. Virulence, 9(1): 522–54. https://doi.org/10.1080/21505594.2017.1313372
  • Sabu R, Soumya KR and Radhakrishnan EK (2017). Endophytic Nocardiopsis sp. from Zingiber officinale with both antiphytopathogenic mechanisms and antibiofilm activity against clinical isolates. 3 Biotech, 7(2): 115. https://doi.org/10.1007/s13205-017-0735-4
  • Saga T and Yamaguchi K (2009). History of antimicrobial agents and resistant bacteria. Japan Medical Association Journal, 52(2): 103-108.
  • Saha ML, Islam KN, Akter T, Rahman IA, Islam T and Khan T (2019). Isolation and identification of amylolytic bacteria from garbage and garden soil. Bangladesh Journal of Botany, 48 (3): 537-545. https://doi.org/10.3329/bjb.v48i3.47915
  • Stauff DL and Bassler BL (2011). Quorum sensing in Chromobacterium violaceum: DNA recognition and gene regulation by the CviR receptor. Journal of Bacteriology, 193 (15): 3871–3878. https://doi.org/10.1128/JB.05125-11
  • Theodora NA, Dominika V and Waturangi DE (2019). Screening and quantification of anti-quorum sensing and antibiofilm activities of phyllosphere bacteria against biofilm forming bacteria BMC Research Notes, 12: 732. https://doi.org/10.1186/s13104-019-4775-1
  • Vattem DA Mihalik K, Crixell SH and McLean RJ (2007). Dietary phytochemicals as quorum sensing inhibitors. Fitoterapia ,78(4): 302-310. https://doi.org/10.1016/j.fitote.2007.03.009
  • Vestby LK, Grønseth T, Simm R and Nesse LL (2020). Bacterial Biofilm and its Role in the Pathogenesis of Disease. Antibiotics (Basel), 3(2): 59. https://doi.org/10.3390/antibiotics9020059
  • Wang HY, Liu DM, Liu Y, Cheng CF, Ma QY, Huang Q and Zhang YZ (2007). Screening and mutagenesis of a novel Bacillus pumilus strain producing alkaline protease for dehairing. Letters in Applied Microbiology, 44 (20): 1-6. https://doi.org/10.1128/JB.183.20.5937-5941.2001
  • Weng LX, Zhang YQ, Meng H, Yang YX, Quan ZX, Zhang YY and Wang LH (2012). Screening and isolating quorum sensing inhibitor from bacteria. African Journal of Microbiology Research, 6(5): 927-936. https://doi.org/10.5897/AJMR11.813
  • You JL, Xue XL, Cao LX, Lu X, Wang J, Zhang LX and Zhou SN (2007). Inhibition of Vibrio biofilm formation by a marine actinomycete strain A66. Applied Microbiology and Biotechnology, 76 (5): 1137-–1144. https://doi.org/10.1007/s00253-007-1074-x
  • Younis KM, Usup G and Ahmad A (2015). Secondary metabolites produced by marine streptomyces as antibiofilm and anti-quorum sensing inhibitor of uropathogen Proteus mirabilis. Environmental Science and Pollution Research, 23(5): 4756–4767. https://doi.org/10.1007/s11356-015-5687-9.
  • Yu Y, Li H, Zeng Y and Chen B (2009). Extracellular enzymes of cold adapted bacteria from Arctic sea ice Canada Basin. Polar Biology, 32: 1539-1547. https://doi.org/10.1007/s00300-009-0654-x
  • Zhou J, Bi S, Chen H, Chen T, Yang R, Li M, Fu Y, Jia A (2017). Anti-biofilm and antivirulence activities of metabolites from Plectospaerella cucumerina against Pseudomonas aeruginosa. Frontiers in Microbiology, 3(8): 1-17. https://doi.org/10.3389/fmicb.2017.00769

Inhibition of Quorum Sensing and Biofilm Development by Walnut Rhizosphere Bacteria

Year 2025, Volume: 6 Issue: 1, 59 - 73, 30.06.2025

Belgin Erdem , İlkay Açıkgöz Erkaya , Dilek Yalçın

https://doi.org/10.46592/turkager.1680203

Abstract

Antibiotic resistance is a significant public health threat, and bacterial biofilms may play a role in the development of resistance to antibiotics. Natural biological agents hold promise for solving this problem due to their antibiofilm properties. In this study, extracts of walnut rhizosphere soil bacteria were used to investigate their anti-quorum sensing and antibiofilm characteristics. Four isolates (BT13, BT31, BT39 and BT40) from the walnut rizosphere demonstrated anti-quorum sensing action against Chromobacterium violaceum ATCC 12472 at dosages of 20 mg mL-1. The crude extracts of BT13 (E. mundtii) showed the highest zone diameter, while crude extracts from BT33 did not. The crude extract from the BT39 (E. faecium) isolate, S. aureus (88%), and L. monocytogenes (82%) have the best biofilm inhibition activity. The study identified two walnut rhizosphere bacteria (BT13 and BT39) that exhibited promising antibiofilm and anti-quorum sensing properties, which could serve as natural biological controls against antibiotic-resistant bacteria. In addition, these bacteria may protect both plant and public health by acting as effective antibiotics against resistant pathogenic organisms.

Keywords

Antibiofilm activity Antiquorum sensing Walnut rhizosphere Enterococcus faecium Enterococcus mundtii

Ethical Statement

This article does not require any Ethical Committee Decision.

Supporting Institution

Kırşehir Ahi Evran University Scientific Research Unit

Project Number

Project No: SAG.A4.21.002

Thanks

Authors are grateful for financial support from Kırşehir Ahi Evran University Scientific Research Unit (Project No: SAG.A4.21.002)

References

  • Abudoleh SM and Mahasneh AM (2017). Anti-quorum sensing activity of substances isolated from wild berry associated bacteria. Avicenna Journal of Medical Biotechnology, 9(1): 23-30.
  • Abdollahzadeh R, Pazhang M, Najavand S, Fallahzadeh-Mamaghani V, Amani-Ghadim AR (2020). Screening of pectinase-producing bacteria from farmlands and optimization of enzyme production from selected strain by RSM. Folia Microbiol, 65: 705-719. https://doi.org/10.1007/s12223-020-00776-7
  • Alam K, Farraj DAA, Mah-E-Fatima S, Yameen MA, Elshikh MS, Alkufeidy RM, Mustafa AEMA, Bhasme P, Alshammari MK, Alkubaisi NA, Abbasi AM and Naqvi TA (2020). Anti-biofilm activity of plant derived extracts against infectious pathogen-Pseudomonas aeruginosa PAO1. Journal of Infection and Public Health, 13(11): 1734-1741.
  • Alatoom AA, Cunningham SA, Ihde S M, Mandrekar J and Patel R (2011). Comparison of Direct Colony Method Versus Extraction Method for Identification of Gram-Positive Cocci by Use of Bruker Biotyper Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry. Journal of Clinical Microbiology, 49(8): 2868–2873. https://doi.org/10.1128/JCM.00506-11
  • Asfour HZ (2018). Anti-Quorum sensing natural compounds. Journal of Microscopy and Ultrastructure, 6(1): 1-10.
  • Basavaraju M, Sisnity VS, Palaparthy R and Addanki PK (2016). Quorum quenching: Signal jamming in dental plaque biofilms. Journal of Dental Sciences, 11(4): 349-352.
  • Bhardwaj AK, Vinothkumar K and Rajpara N (2013). Bacterial quorum sensing inhibitors: Attractive alternatives for control of infectious pathogens showing multiple drug resistance. Recent Patents on Anti-Infective Drug Discovery, 8(1): 68-83.
  • Biradar B and Devi P (2011). Quorum sensing in plaque biofilms: challenges and future prospects. Journal of Contemporary Dental Practice, 12(6): 479-485. https://doi.org/10.5005/jp-journals-10024-1080
  • Bizzini A, Durussel C, Bille J, Greub G and Prod'hom G (2010). Performance of matrix-assisted laser desorption ionization-time of flight mass spectrometry for identification of bacterial strains routinely isolated in a clinical microbiology laboratory. Journal of Clinical Microbiology, 48(5): 1549-1554. https://doi.org/10.1128/JCM.01794-09
  • Brackman G, Cos P, Maes L, Nelis H and Coenye T (2011). Quorum sensing inhibitors increase the susceptibility of bacterial biofilms to antibiotics in vitro and in vivo. Antimicrobial Agents and Chemotherapy, 55 (6): 2655-61. https://doi.org/10.1128/AAC.00045-11
  • Cegelski L, Marshall GR, Eldridge GR and Hultgren SJ (2008). The biology and future prospects of antivirulence therapies. Nat Rev Microbiol, 6 (1): 17-27. https://doi.org/10.1038/nrmicro1818.
  • Chikere CB and Udochukwu U (2014) Effect of growth media and incubation time on the culturability of soil bacteria. IOSR Journal of Pharmacy and Biological Sciences, 9(2):6-9. https://doi.org/10.9790/3008-09210609
  • Choo JH, Rukayadi Y and Hwang JK (2006). Inhibition of bacterial quorum sensing by vanilla extract. Letters in Applied Microbiology, 42(6): 637-641. https://doi.org/10.1111/j.1472-765X.2006.01928.x
  • Dadi NCT, Radochová B, Vargová J and Bujdáková H (2021). Impact of Healthcare-Associated Infections Connected to Medical Devices-An Update. Microorganisms, 9 (11): 2332. https://doi.org/10.3390/microorganisms9112332
  • Devi KR, Srinivasan S and Ravi AV (2018). Inhibition of quorum sensing-mediated virulence in Serratia marcescens by Bacillus subtilis R-18. Microbial Pathogenesis, 120: 166-175. https://doi.org/10.1016/j.micpath.2018.04.023
  • Donlan, RM (2002). Biofilms: Microbial Life on Surfaces. Emerging Infectious Diseases, 8(9): 881-890. https://doi.org/10.3201/eid0809.020063
  • Fleming D and Rumbaugh KP (2017). Approaches to dispersing medical biofilms. Microorganisms, 5(2): 15. https://doi.org/10.3390/microorganisms5020015
  • Grandclement C, Tannieres M, Morera S, Dessaux Y and Faure D (2016). Quorum quenching: role in nature and applied developments. FEMS Microbiology Reviews, 40(1): 86–116. https://doi.org/10.1093/femsre/fuv038
  • Gunn JS, Bakaletz LO and Wozniak DJ (2016). What’s on the outside matters: the role of the extracellular polymeric substance of Gram-negative biofilms in evading host immunity and as a target for therapeutic intervention. Journal of Biological Chemistry, 291(24): 12538-12546. https://doi.org/10.1074/jbc.R115.707547
  • Ghosh S, Bornman C and Zafer MM (2021). Antimicrobial resistance threats in the emerging COVID-19 pandemic: Where do we stand? Journal of Infection and Public Health, 14(5): 555-560. https://doi.org/10.1016/j.jiph.2021.02.011
  • Høiby N, Bjarnsholt T, Givskov M, Molin S and Ciofu O (2010.) Antibiotic resistance of bacterial biofilms. International Journal of Antimicrobial Agents, 35 (4): 222–332. https://doi.org/10.1016/j.ijantimicag.2009.12.011
  • Hughes G and Webber MA (2017). Novel approaches to the treatment of bacterial biofilm infections. British Journal of Pharmacology, 174(14): 2237-2246. https://doi.org/10.1111/bph.13706
  • Hunter PJ, Hand P, Pink D, Whipps JM and Bending GD (2010). Both leaf properties and microbe–microbe interactions influence within-species variation in bacterial population diversity and structure in the lettuce (Lactuca species) phyllosphere. Applied and Environmental Microbiology, 76(24): 8117–8125. https://doi.org/10.1128/AEM.01321-10
  • Kanagasabhapthy M, Yamazaki G, Ishida A, Sasaki H and Nagata S (2009). Presence of quorum-sensing inhibitors-like compounds from bacteria isolated from the brown alga Colpomenia sinusoa. Letters in Applied Microbiology, 49(5): 573-579. https://doi.org/10.1111/j.1472-765x.2009.02712.x
  • Khan MS, Zahin M, Hasan S, Husain F, and Ahmad I (2009). Inhibition of quorum sensing regulated bacterial functions by plant essential oils with special reference to clove oil. Letters in Applied Microbiology, 49(3): 354-360. https://doi.org/10.1111/j.1472-765X.2009.02666.x
  • Khan J, Tarar SM, Gul I, Nawaz U and Arshad M (2021). Challenges of antibiotic resistance biofilms and potential combating strategies: a review. 3 Biotech, 11(4): 169. https://doi.org/10.1007/s13205-021-02707-w
  • Kim EK, Jang, WH, Ko JH, Kang JS, Noh, MJ and Yoo OJ (2001). Lipase and its modulator from Pseudomonas sp. strain KFCC 10818: Proline-to-glutamine substitution at position 112 induces formation of enzymatically active lipase in the absence of the modulator. Journal of Bacteriology, 183(20): 5937-41. https://doi.org/10.1128/JB.183.20.5937-5941.2001
  • Leme AFP, Koo H, Bellato CM, Bedi G and Cury JA (2006). The Role of Sucrose in Cariogenic Dental Biofilm Formation-New. Insight. Journal of Dental Research, 85(10): 878-887. https://doi.org/10.1177/154405910608501002
  • Lobritz MA, Belenky P, Porter CB, Gutierrez A, Yang JH, Schwarz EG, Dwyer DJ, Khalil AS and Collins JJ (2015). Antibiotic efficacy is linked to bacterial cellular respiration. Proceedings of the National Academy of Sciences of the United States of America, 112,(27): 8173-8180. https://doi.org/10.1073/pnas.1509743112
  • Lokegaonkar SP and Nabar BM (2017). In Vitro Antibiofilm, Antiquorum Sensing Activity of Gamma Tolerant Streptomyces Against Gram Negative Pathogens. International Journal of Pharmacology and Clinical Research, 9 (11): 665-670.
  • Ma A, Lv D, Zhuang X and Zhuang G (2013). Quorum quenching in culturable phyllosphere bacteria from tobacco. International Journal of Molecular Sciences, 14(7): 14607–14619. https://doi.org/10.3390/ijms140714607
  • Maeda T, García-Contreras R, Pu M, Sheng L, Garcia LR, Tomás M and Wood TK (2012). Quorum quenching quandary: resistance to antivirulence compounds. ISME Journal 6, 493-501. https://doi.org/10.1038/ismej.2011.122
  • Miller MB and Bassler BL (2001). Quorum sensing in bacteria. Annual Review of Microbiology, 55: 165-199. https://doi.org/10.1146/annurev.micro.55.1.165
  • Nadell C, Xavier J, Levin S and Foster K (2008). The evolution of quorum sensing in bacterial biofilms. PLOS Biology, 6 (1):171– 179. https://doi.org/10.1371/journal.pbio.0060014
  • Nithya C, Begum MF and Pandian SK (2010a). Marine bacterial isolates inhibit biofilm formation and disrupt mature biofilms of Pseudomonas aeruginosa PAO1. Applied Microbiology and Biotechnology, 88(1): 341-358. https://doi.org/10.1007/s00253-010-2777-y
  • Nithya C, Aravindraja C and Pandian SK (2010b). Bacillus pumilus of Palk Bay origin inhibits quorum-sensing-mediated virulence factors in Gram-negative bacteria. Research in Microbiology, 161(4): 293-304. https://doi.org/10.1016/j.resmic.2010.03.002
  • Packiavathy IA, Agilandeswari P, Mustafa KS, Pandian SK and Ravi AV (2012). Antibiofilm and quorum sensing inhibitory potential of Cuminum cyminum and its secondary metabolite methyl eugenol against Gram negative bacterial pathogens. Food Research International, 45(1): 85-92. https://doi.org/10.1016/j.foodres.2011.10.022
  • Rajput M and Bithel N (2022). Phytochemical characterization and evaluation of antioxidant, antimicrobial, antibiofilm and anticancer activities of ethyl acetate seed extract of Hydnocarpus laurifolia (Dennst) Sleummer. 3 Biotech ,12(9): 215. https://doi.org/10.1007/s13205-022-03267-3
  • Relucenti M, Familiari G, Donfrancesco O, Taurino M, Li X, Chen R, Artini M, Papa R and Selan L (2021). Microscopy Methods for Biofilm Imaging: Focus on SEM and VP-SEM Pros and Cons. Biology (Basel). 12;10 (1):51. https://doi.org/1010.3390/biology10010051
  • Roy R, Tiwari M, Donelli G and Tiwari V (2018). Strategies for combating bacterial biofilms: a focus on anti-biofilm agents and their mechanisms of action. Virulence, 9(1): 522–54. https://doi.org/10.1080/21505594.2017.1313372
  • Sabu R, Soumya KR and Radhakrishnan EK (2017). Endophytic Nocardiopsis sp. from Zingiber officinale with both antiphytopathogenic mechanisms and antibiofilm activity against clinical isolates. 3 Biotech, 7(2): 115. https://doi.org/10.1007/s13205-017-0735-4
  • Saga T and Yamaguchi K (2009). History of antimicrobial agents and resistant bacteria. Japan Medical Association Journal, 52(2): 103-108.
  • Saha ML, Islam KN, Akter T, Rahman IA, Islam T and Khan T (2019). Isolation and identification of amylolytic bacteria from garbage and garden soil. Bangladesh Journal of Botany, 48 (3): 537-545. https://doi.org/10.3329/bjb.v48i3.47915
  • Stauff DL and Bassler BL (2011). Quorum sensing in Chromobacterium violaceum: DNA recognition and gene regulation by the CviR receptor. Journal of Bacteriology, 193 (15): 3871–3878. https://doi.org/10.1128/JB.05125-11
  • Theodora NA, Dominika V and Waturangi DE (2019). Screening and quantification of anti-quorum sensing and antibiofilm activities of phyllosphere bacteria against biofilm forming bacteria BMC Research Notes, 12: 732. https://doi.org/10.1186/s13104-019-4775-1
  • Vattem DA Mihalik K, Crixell SH and McLean RJ (2007). Dietary phytochemicals as quorum sensing inhibitors. Fitoterapia ,78(4): 302-310. https://doi.org/10.1016/j.fitote.2007.03.009
  • Vestby LK, Grønseth T, Simm R and Nesse LL (2020). Bacterial Biofilm and its Role in the Pathogenesis of Disease. Antibiotics (Basel), 3(2): 59. https://doi.org/10.3390/antibiotics9020059
  • Wang HY, Liu DM, Liu Y, Cheng CF, Ma QY, Huang Q and Zhang YZ (2007). Screening and mutagenesis of a novel Bacillus pumilus strain producing alkaline protease for dehairing. Letters in Applied Microbiology, 44 (20): 1-6. https://doi.org/10.1128/JB.183.20.5937-5941.2001
  • Weng LX, Zhang YQ, Meng H, Yang YX, Quan ZX, Zhang YY and Wang LH (2012). Screening and isolating quorum sensing inhibitor from bacteria. African Journal of Microbiology Research, 6(5): 927-936. https://doi.org/10.5897/AJMR11.813
  • You JL, Xue XL, Cao LX, Lu X, Wang J, Zhang LX and Zhou SN (2007). Inhibition of Vibrio biofilm formation by a marine actinomycete strain A66. Applied Microbiology and Biotechnology, 76 (5): 1137-–1144. https://doi.org/10.1007/s00253-007-1074-x
  • Younis KM, Usup G and Ahmad A (2015). Secondary metabolites produced by marine streptomyces as antibiofilm and anti-quorum sensing inhibitor of uropathogen Proteus mirabilis. Environmental Science and Pollution Research, 23(5): 4756–4767. https://doi.org/10.1007/s11356-015-5687-9.
  • Yu Y, Li H, Zeng Y and Chen B (2009). Extracellular enzymes of cold adapted bacteria from Arctic sea ice Canada Basin. Polar Biology, 32: 1539-1547. https://doi.org/10.1007/s00300-009-0654-x
  • Zhou J, Bi S, Chen H, Chen T, Yang R, Li M, Fu Y, Jia A (2017). Anti-biofilm and antivirulence activities of metabolites from Plectospaerella cucumerina against Pseudomonas aeruginosa. Frontiers in Microbiology, 3(8): 1-17. https://doi.org/10.3389/fmicb.2017.00769
There are 53 citations in total.

Details

Primary Language English
Subjects Animal Biotechnology in Agriculture
Journal Section Research Articles
Authors

Belgin Erdem 0000-0001-9108-5561

İlkay Açıkgöz Erkaya 0000-0003-1730-4951

Dilek Yalçın 0000-0003-2127-8186

Project Number Project No: SAG.A4.21.002
Early Pub Date June 27, 2025
Publication Date June 30, 2025
Submission Date April 20, 2025
Acceptance Date June 25, 2025
Published in Issue Year 2025 Volume: 6 Issue: 1

Cite

APA Erdem, B., Açıkgöz Erkaya, İ., & Yalçın, D. (2025). Inhibition of Quorum Sensing and Biofilm Development by Walnut Rhizosphere Bacteria. Turkish Journal of Agricultural Engineering Research, 6(1), 59-73. https://doi.org/10.46592/turkager.1680203
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