Multidisciplinary Rehabilitation of Ectodermal Dysplasia Using 3D-Printed Crowns and Conventional Removable Dentures: A Case Report
Öz
Introduction: Ectodermal dysplasia is a rare hereditary condition characterized by developmental defects in ectodermal-derived tissues and organs. In cases of ectodermal dysplasia, missing teeth (anodontia,
hypodontia), conically shaped teeth, inadequate development of the alveolar crests, and loss of vertical dimension are observed. Due to the lack of most primary and permanent teeth during childhood, the esthetic and chewing functions of these patients need to be restored with a multidisciplinary treatment approach in the early period. This case report describes the rehabilitation of a child patient with ectodermal dysplasia using three-dimensional (3D) printed crown prostheses for existing upper central teeth and removable prostheses for additional missing teeth.
Case Report: The treatment of a 10-year-old child patient who applied to Gazi University, Faculty of Dentistry, due to missing teeth was carried out and completed jointly by the Departments of Pediatric Dentistry and Prosthodontics. The extraoral examination of the patient, who was diagnosed with ectodermal dysplasia, revealed sparse eyebrows, hair, and eyelashes, dry and thin skin, and sagging and swollen lips. Intraoral examination identified only two conical-shaped maxillary central teeth. All
procedures to be performed were explained to the patient and their parents, and their consent was obtained. As a result of the prosthetic analysis, it was decided to make a crown restoration for the existing teeth and an upper and lower removable prosthesis for the missing teeth. After tooth preparations,
permanent resin crowns were fabricated using 3D printing technology and cemented onto the prepared teeth. The removable prostheses for the upper and lower jaws were completed using traditional methods and delivered to the patient, who was scheduled for follow-up appointments.
Conclusion: Early multidisciplinary intervention is crucial for patients with ectodermal dysplasia starting from childhood due to significant tooth loss, aiming to restore both esthetics and functionality. The goal in designing prostheses is to preserve existing teeth, esthetically restore conical-shaped teeth, and prevent resorption of the alveolar ridges. The application of 3D printing in pediatric dentistry holds substantial potential, offering an aesthetically pleasing, durable, and cost-effective alternative for prosthetic
restorations in child patients with ectodermal dysplasia.
Anahtar Kelimeler
3D printing Additive manufacturing Ectodermal dysplasia Pediatric dentistry Prosthetic Rehabilitation
Kaynakça
- Abdulla AM, Almaliki AY, Shakeela NV, Alkahtani Z, Alqahtani MA, Sainudeen S, et al. Prosthodontic management of a pediatric patient with Christ-Siemens-Touraine Syndrome: A case report. Int J Clin Pediatr Dent 2019;12:569-72.
- Bolaca A, Demirciler Mİ, Gültekin Kuru A. Prosthetic treatment of pediatric patients with Ectodermal Dysplasia: Two case reports. Turkish J Pediatr Dis 2023;17:501-5.
- Montanari M, Grande F, Lepidi L, Piana G, Catapano S. Rehabilitation with implant-supported overdentures in preteens patients with ectodermal dysplasia: A cohort study. Clin Implant Dent Relat Res 2023;25:1187-96.
- Hsieh YL, Razzoog M, Garcia Hammaker S. Oral Care Program for Successful Long-Term Full Mouth Habilitation of Patients with Hypohidrotic Ectodermal Dysplasia. Case Rep Dent 2018;2018:4736495.
- Ruhin B, Martinot V, Lafforgue P, Catteau B, Manouvrier-Hanu S, Ferri J. Pure ectodermal dysplasia: retrospective study of 16 cases and literature review. Cleft Palate Craniofac J 2001;38:504-18.
- Yap AKW, Klineberg I. Dental implants in patients with ectodermal dysplasia and tooth agenesis: a critical review of the literature. Int J Prosthodont 2009;22:268-76.
- Cardoso JS, Faria Carvalho D, Carvalho Silva C, Moura Teles A, Leal F, Lopes Cardoso I. Hypohidrotic ectodermal dysplasia and its manifestations in the oral cavity. J Dent & Oral Disord 2021;7:1161-8.
- Saksena SS, Bixler D. Facial morphometrics in the identification of gene carriers of X-linked hypohidrotic ectodermal dysplasia. Am J Med Genet 1990;35:105-14.
- Van Sickels JE, Raybould TP, Hicks EP. Interdisciplinary management of patients with ectodermal dysplasia. J Oral Implantol 2010;36:239-45.
- Aktaş N, Ciftci V. Current applications of three-dimensional (3D) printing in pediatric dentistry: a literature review. Journal of Clinical Pediatric Dentistry. 2024;48:4-13.
- AlNuaimi R, Mansoor M. Prosthetic rehabilitation with fixed prosthesis of a 5-year-old child with Hypohidrotic Ectodermal Dysplasia and Oligodontia: a case report. J Med Case Rep 2019;13:329-33.
- Schnabl D, Grunert I, Schmuth M, Kapferer-Seebacher I. Prosthetic rehabilitation of patients with hypohidrotic ectodermal dysplasia: a systematic review. J Oral Rehabil 2018;45:555–70.
- Nejabi MB, Anwari A, Shadab H, Mtawakel N, Omarzad F, Ahmadi ME. Prosthodontic Management of a Patient with Ectodermal Dysplasia: Case Report. Clin Cosmet Investig Dent 2023;15:133-41.
- Jain N, Naitam D, Wadkar A, Nemane A, Katoch S, Dewangan A. Prosthodontic rehabilitation of hereditary ectodermal dysplasia in an 11-year-old patient with flexible denture: a case report. Case Rep Dent 2012;2012:489769.
- Alqarni H, Alzeghaibi F, Alotaibi S, et al. Rehabilitation of Ectodermal Dysplasia Using CAD/CAM Mandibular Complete Denture and Maxillary Overdenture: A Clinical Report. Case Rep Dent 2024;2024:9705699.
- Thulasingam C, Akshayalingam M, Vashisht P. Early prosthodontic intervention in a child patient of hypohidroticectodermal dysplasia. SRM J Res Dent Sci 2013;4:73-7.
- Khinda VI, Khinda P, Brar GS, Yadav A. Prosthodontic rehabilitation of a pediatric patient affected with anhidrotic ectodermal dysplasia: A rare case report. J Interdiscip Dentistry 2016;6:25-8.
- Török G, Saláta J, Ábrám E, Nemes B, Hermann P, Rózsa N, et al. Prosthetic rehabilitation of a patient with ectrodactylyectodermal dysplasia-cleft lip/palate syndrome through a hybrid workflow: A case report with 2-year follow-up. Spec Care Dentist 2024;44:96-102.
- Seremidi K, Markouli A, Agouropoulos A, Polychronakis N, Gizani S. Rehabilitation Considerations for Very Young Children with Severe Oligodontia due to Ectodermal Dysplasia: Report of Three Clinical Cases with a 2-Year Follow-Up. Case Rep Dent 2022;2022:9925475.
- Sun X, Yang J, Ma X, Liu S, Zhang J. Complex Rehabilitation for an Adolescent with Ectodermal Dysplasia-A 10-Year FollowUp. J Prosthodont 2021;30:7-12.
Ektodermal Displazinin 3D Baskı Kronlar ve Geleneksel Hareketli Protezler Kullanılarak Multidisipliner Rehabilitasyonu: Bir Olgu Sunumu
Öz
Giriş: Ektodermal displazi, ektodermal kaynaklı doku ve organların gelişimsel kusurları ile karakterize nadir bir kalıtsal durumdur. Ektodermal displazi vakalarında eksik dişler (anodonti, hipodonti), konik biçimli dişler, alveolar kretlerin yetersiz gelişimi ve dikey boyut kaybı gözlenir. Çocukluk döneminde birincil ve kalıcı dişlerin çoğunun eksik olması nedeniyle, bu hastaların estetik ve çiğneme fonksiyonlarının erken dönemde multidisipliner bir tedavi yaklaşımı ile restore edilmesi gerekmektedir. Bu olgu sunumu, ektodermal displazili bir çocuk hastanın mevcut üst santral dişleri için üç boyutlu (3B) baskı kronlar ve eksik dişler için hareketli protezler kullanılarak rehabilitasyonunu anlatmaktadır.
Vaka Raporu: Gazi Üniversitesi Diş Hekimliği Fakültesi’ne eksik dişler nedeniyle başvuran 10 yaşındaki bir çocuk hastanın tedavisi, Çocuk Diş Hekimliği ve Protetik Diş Tedavisi Anabilim Dalları tarafından birlikte
gerçekleştirilmiş ve tamamlanmıştır. Ektodermal displazi tanısı konan hastanın ekstraoral muayenesinde seyrek kaşlar, saç ve kirpikler, kuru ve ince cilt, sarkık ve şiş dudaklar gözlenmiştir. İntraoral muayenede
yalnızca iki konik biçimli maksiller santral diş tespit edilmiştir. Yapılacak tüm işlemler hasta ve ailesine açıklanmış ve onayları alınmıştır. Protetik analiz sonucunda mevcut dişler için kron restorasyonu ve eksik dişler için üst ve alt hareketli protez yapılmasına karar verilmiştir. Diş preparasyonunun ardından, 3D baskı teknolojisi kullanılarak daimi rezin kronlar üretilmiş ve prepare edilmiş dişlere simante edilmiştir. Üst ve alt çeneler için hareketli protezler geleneksel yöntemler kullanılarak tamamlanmış ve hastaya teslim edilmiştir; hastaya takip randevuları planlanmıştır.
Sonuç: Çocukluk döneminden itibaren ciddi diş kaybı olan Ektodermal displazi hastalarında, estetik ve fonksiyonelliği geri kazandırmayı amaçlayan erken multidisipliner müdahale çok önemlidir. Protezlerin
tasarımındaki amaç, mevcut dişleri korumak, konik biçimli dişleri estetik olarak restore etmek ve alveolar kretlerin rezorpsiyonunu önlemektir. Çocuk diş hekimliği alanında 3D baskı uygulaması, Ektodermal displazili çocuk hastalar için estetik açıdan tatmin edici, dayanıklı ve maliyet etkin bir alternatif sunan büyük bir potansiyele sahiptir.
Anahtar Kelimeler
3D baskı Çocuk Diş Hekimliği Eklemeli imalat Ektodermal Displazi Protetik Rehabilitasyon
Kaynakça
- Abdulla AM, Almaliki AY, Shakeela NV, Alkahtani Z, Alqahtani MA, Sainudeen S, et al. Prosthodontic management of a pediatric patient with Christ-Siemens-Touraine Syndrome: A case report. Int J Clin Pediatr Dent 2019;12:569-72.
- Bolaca A, Demirciler Mİ, Gültekin Kuru A. Prosthetic treatment of pediatric patients with Ectodermal Dysplasia: Two case reports. Turkish J Pediatr Dis 2023;17:501-5.
- Montanari M, Grande F, Lepidi L, Piana G, Catapano S. Rehabilitation with implant-supported overdentures in preteens patients with ectodermal dysplasia: A cohort study. Clin Implant Dent Relat Res 2023;25:1187-96.
- Hsieh YL, Razzoog M, Garcia Hammaker S. Oral Care Program for Successful Long-Term Full Mouth Habilitation of Patients with Hypohidrotic Ectodermal Dysplasia. Case Rep Dent 2018;2018:4736495.
- Ruhin B, Martinot V, Lafforgue P, Catteau B, Manouvrier-Hanu S, Ferri J. Pure ectodermal dysplasia: retrospective study of 16 cases and literature review. Cleft Palate Craniofac J 2001;38:504-18.
- Yap AKW, Klineberg I. Dental implants in patients with ectodermal dysplasia and tooth agenesis: a critical review of the literature. Int J Prosthodont 2009;22:268-76.
- Cardoso JS, Faria Carvalho D, Carvalho Silva C, Moura Teles A, Leal F, Lopes Cardoso I. Hypohidrotic ectodermal dysplasia and its manifestations in the oral cavity. J Dent & Oral Disord 2021;7:1161-8.
- Saksena SS, Bixler D. Facial morphometrics in the identification of gene carriers of X-linked hypohidrotic ectodermal dysplasia. Am J Med Genet 1990;35:105-14.
- Van Sickels JE, Raybould TP, Hicks EP. Interdisciplinary management of patients with ectodermal dysplasia. J Oral Implantol 2010;36:239-45.
- Aktaş N, Ciftci V. Current applications of three-dimensional (3D) printing in pediatric dentistry: a literature review. Journal of Clinical Pediatric Dentistry. 2024;48:4-13.
- AlNuaimi R, Mansoor M. Prosthetic rehabilitation with fixed prosthesis of a 5-year-old child with Hypohidrotic Ectodermal Dysplasia and Oligodontia: a case report. J Med Case Rep 2019;13:329-33.
- Schnabl D, Grunert I, Schmuth M, Kapferer-Seebacher I. Prosthetic rehabilitation of patients with hypohidrotic ectodermal dysplasia: a systematic review. J Oral Rehabil 2018;45:555–70.
- Nejabi MB, Anwari A, Shadab H, Mtawakel N, Omarzad F, Ahmadi ME. Prosthodontic Management of a Patient with Ectodermal Dysplasia: Case Report. Clin Cosmet Investig Dent 2023;15:133-41.
- Jain N, Naitam D, Wadkar A, Nemane A, Katoch S, Dewangan A. Prosthodontic rehabilitation of hereditary ectodermal dysplasia in an 11-year-old patient with flexible denture: a case report. Case Rep Dent 2012;2012:489769.
- Alqarni H, Alzeghaibi F, Alotaibi S, et al. Rehabilitation of Ectodermal Dysplasia Using CAD/CAM Mandibular Complete Denture and Maxillary Overdenture: A Clinical Report. Case Rep Dent 2024;2024:9705699.
- Thulasingam C, Akshayalingam M, Vashisht P. Early prosthodontic intervention in a child patient of hypohidroticectodermal dysplasia. SRM J Res Dent Sci 2013;4:73-7.
- Khinda VI, Khinda P, Brar GS, Yadav A. Prosthodontic rehabilitation of a pediatric patient affected with anhidrotic ectodermal dysplasia: A rare case report. J Interdiscip Dentistry 2016;6:25-8.
- Török G, Saláta J, Ábrám E, Nemes B, Hermann P, Rózsa N, et al. Prosthetic rehabilitation of a patient with ectrodactylyectodermal dysplasia-cleft lip/palate syndrome through a hybrid workflow: A case report with 2-year follow-up. Spec Care Dentist 2024;44:96-102.
- Seremidi K, Markouli A, Agouropoulos A, Polychronakis N, Gizani S. Rehabilitation Considerations for Very Young Children with Severe Oligodontia due to Ectodermal Dysplasia: Report of Three Clinical Cases with a 2-Year Follow-Up. Case Rep Dent 2022;2022:9925475.
- Sun X, Yang J, Ma X, Liu S, Zhang J. Complex Rehabilitation for an Adolescent with Ectodermal Dysplasia-A 10-Year FollowUp. J Prosthodont 2021;30:7-12.
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Konular | Çocuk Diş Hekimliği |
| Bölüm | Olgu Sunumu |
| Yazarlar | |
| Yayımlanma Tarihi | 26 Mayıs 2025 |
| Gönderilme Tarihi | 17 Temmuz 2024 |
| Kabul Tarihi | 19 Mart 2025 |
| Yayımlandığı Sayı | Yıl 2025 Cilt: 14 Sayı: 2 |
