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Akut Bakteriyel Sinüzit Tanısı Konulan Çocukların Değerlendirilmesi: Tek Merkez Deneyimi

Yıl 2019, Cilt: 72 Sayı: 2, 134 - 139, 02.10.2019

Öz

Amaç: Akut bakteriyel sinüzit (ABS) çocukluk çağının sık görülen enfeksiyonlarındandır. Tanısı komplikasyon şüphesi olmadıkça klinik olarak konulmaktadır. Bu çalışmanın amacı çocuk hekimlerinin ABS konusunda klinik yaklaşımlarının değerlendirilmesidir.

Gereç ve Yöntem: Bu retrospektif çalışmada Haziran 2015-Haziran 2018 arasında hastanemiz genel polikliniğinde ABS tanısı alan hastaların tanı, tedavi ve komplikasyon verileri araştırılmıştır.

Bulgular: Çalışma grubunu 536 hasta [kız/erkek 235/301 (%43,8/%56,2)] oluşturdu. Yaş ortancası 6,6 (7 ay-17,9 yıl) yıldı. Ortanca yakınma süresi 7 (1-46) gündü. Başlıca yakınmalar öksürük (n=379, %70,7), burun akıntısı (n=234, %43,7) ve ateş yüksekliği (n=168, %31,3) idi. Yakınma süresi kaydedilen 468 hastanın 198’inde (%42,3) uzamış (>10 gün) üst solunum yolu enfeksiyonu (ÜSYE), 8’inde (%1,7) şiddetli ÜSYE mevcuttu. Kötüleşen ÜSYE olan hasta sayısı kayıt yetersizliği nedeniyle belirlenemedi. Yetmiş altı (%16,2) hastanın yakınma süresi 3 günden kısaydı. Fizik incelemede postnazal akıntı (n=393, %73,3), başın öne eğilmesiyle alında ağrı (n=26, %4,9) ve sinüslere basıyla hassasiyet (n=25, %4,7) mevcuttu. Waters sinüs grafisi 38 hastada (%7,1) çekilmişti. En sık tercih edilen antibiyotikler amoksisilin-klavulonat 167 (%78,4), klaritromisin 18 (%8,5) ve sefdinir 13 (%6,1) idi. Semptomatik tedaviler nadiren reçete edilmişti [nazal dekonjestan (n=38, %17,8), sistemik antihistaminik (n=23, %10,8]. Tedavi süresi ortancası 10 (3-30) gün idi. Beş hasta (%0,9) komplikasyon nedeniyle hospitalize edilmişti [preseptal selülit (n=4), fasiyal selülite ikincil frontal kemik osteomiyeliti, subdural apse (n=1)]. Preseptal selülit tanısı alan hastalar parenteral ampisilin-sulbaktam, frontal osteomiyelit ve apsesi olan hasta apse drenajı sonrası seftriakson, vankomisin ve metronidazol tedavisi almıştı.

Sonuç: Çalışmamızda ABS tanısında güncel kılavuzlarda önerilen klinik tanımlamalara uyum tam olmasa da tanının büyük oranda klinik olarak konulduğu ve antibiyotik tedavi planının sıklıkla doğru olduğu görülmüştür. Bununla birlikte nadiren de olsa tanı amaçlı ek incelemelerin yapıldığı ve/veya semptomatik tedavilerin reçete edildiği dikkati çekmiştir. Klinisyenlerin hasta kayıtlarının eksiksiz olması ve güncel kılavuzlara uyum konusunda desteklenmesi gerektiği vurgulanmak istenmiştir.

Etik Beyan

Bu çalışma için etik komite onayı alınmıştır.

Destekleyen Kurum

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Proje Numarası

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Teşekkür

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Kaynakça

  • 1. Wald ER, Applegate KE, Bordley C, et al. American Academy of Pediatrics. Clinical practice guideline for the diagnosis and management of acute bacterial sinusitis in children aged 1 to 18 years. Pediatrics. 2013;132:e262-e280.
  • 2. DeMuri G, Wald ER. Acute bacterial sinusitis in children. Pediatr Rev. 2013;34:429-437.
  • 3. Wald ER. Acute bacterial sinusitis in children: Clinical features and diagnosis. Kaplan SL, Wood RA, Isacson GC, ed. UpToDate. Torchia MM: UpToDate Inc https://www.uptodate.com/ (Accessed on May 5, 2019).
  • 4. Chow AW, Benninger MS, Brook I, et al. Infectious Diseases Society of America. IDSA clinical practice guideline for acute bacterial rhinosinusitis in children and adults.Clin Infect Dis. 2012;54:e72-e112.
  • 5. Peters AT, Spector S, Hsu J, et al. Joint Task Force on Practice Parameters, representing the American Academy of Allergy, Asthma and Immunology, the American College of Allergy, Asthma and Immunology, and the Joint Council of Allergy, Asthma and Immunology. Diagnosis and management of rhinosinusitis: a practice parameter update. Ann Allergy Asthma Immunol. 2014;113:347-385.
  • 6. Cherry JD, Kuan EC, Shapiro NL. In: Cherry JD, Harrison G, Kaplan SL, et al, editors. Feigin and Cherry’s Textbook of Pediatric Infectious Diseases. 8th ed, Philadelphia: Elsevier; 2018.p.137.
  • 7. Pappas DE, Hendley JO, Hayden FG, et al. Symptom profile of common colds in school-aged children. Pediatr Infect Dis J. 2008;27:8-11.
  • 8. Wald ER, Milmoe GJ, Bowen A, et al. Acute maxillary sinusitis in children. N Eng J Med. 1981;304:749-54.
  • 9. Tekes A, Palasis S, Durand DJ, et al; Expert Panel on Pediatric Imaging. ACR Appropriateness Criteria® Sinusitis-Child. J Am Coll Radiol. 2018;15:S403-S412.
  • 10. Wald ER. Acute bacterial sinusitis in children: Microbiology and treatment. Kaplan SL, Isacson GC, Wood RA, sec ed. UpToDate. Torchia MM: UpToDate Inc https://www.uptodate.com/ (Accessed on May 5, 2019).
  • 11. Shaikh N, Wald ER. Decongestants, antihistamines and nasal irrigation for acute sinusitis in children. Cochrane Database Syst Rev. 2014;10:CD007909.
  • 12. Gallant JN, Basem JI, Turner JH, et al. Nasal saline irrigation in pediatric rhinosinusitis: A systematic review. Int J Pediatr Otorhinolaryngol. 2018;108:155-162.
  • 13. Germiller JA, Monin DL, Sparano AM, et al. Intracranial complications of sinusitis in children and adolescents and their outcomes. Arch Otolaryngol Head Neck Surg. 2006; 132:969-976.
  • 14. DeMuri GP, Gern JE, Moyer SC, et al. Clinical Features, Virus Identification, and Sinusitis as a Complication of Upper Respiratory Tract Illness in Children Ages 4-7 Years. J Pediatr. 2016;171:133-9.e1.
  • 15. Newton L, Kotowski A, Grinker M, et al. Diagnosis and management of pediatric sinusitis: A survey of primary care, otolaryngology and urgent care providers. Int J Pediatr Otorhinolaryngol. 2018;108:163-167.
  • 16. Kovatch AL, Wald ER, Ledesma-Medina J, et al. Maxillary sinus radiographs in children with nonrespiratory complaints. Pediatrics. 1984;73:306-308.
  • 17. Younis RT, Anand VK, Davidson B. The role of computed tomography and magnetic resonance imaging in patients with sinusitis with complications. Laryngoscope. 2002;112:224-229.
  • 18. Shapiro DJ, Gonzales R, Cabana MD, et al. National trends in visit rates and antibiotic prescribing for children with acute sinusitis. Pediatrics. 2011;127:28-34.
  • 19. Kaur R, Morris M, Pichichero ME. Epidemiology of Acute Otitis Media in the Postpneumococcal Conjugate Vaccine Era Pediatrics. 2017;140.
  • 20. Wald ER, DeMuri GP. Antibiotic Recommendations for Acute Otitis Media and Acute Bacterial Sinusitis: Conundrum No More. Pediatr Infect Dis J. 2018;37:1255-1257.
  • 21. Brook I. Microbiology and antimicrobial treatment of orbital and intracranial complications of sinusitis in children and their management. Int J Pediatr Otorhinolaryngol. 2009;73:1183-1186.
  • 22. Doğru Ü. Preseptal ve Orbital Sellülit. J Pediatr Inf. 2009;3:90-93.

Evaluation of Children Diagnosed with Acute Bacterial Sinusitis: Single-center Experience

Yıl 2019, Cilt: 72 Sayı: 2, 134 - 139, 02.10.2019

Öz

Objectives: Acute bacterial sinusitis (ABS) is among frequent infections in children. Its diagnosis is clinical unless a suspicion of complication exists. This study aimed to evaluate pediatricians’ clinical approaches to ABS.

Materials and Methods: This retrospective study analyzed diagnosis, treatment and complication data of patients diagnosed with ABS between June 2015 and June 2018 in our pediatric primary care unit.

Results: The study group consisted of 536 patients [female/male 235/301 (43.8%/56.2%)]. The median age was 6.6 (7 months-17.9 years) years. Median duration of symptoms was 7 (1-46) days. Major complaints were cough (n=379, 70.7%), nasal discharge (n=234, 43.7%) and fever (n=168, 31.3%). Among 468 patients with available data, persistent (>10 days) upper respiratory tract infection (URTI) was present in 198 (42.3%) while 8 (1.7%) had severe URTI. Worsening URTI data could not be defined because of inadequate records. Duration of symptoms was <3 days in 26 (16.2%) patients. Physical examination revealed postnasal discharge (n=393, 73.3%), frontal pain (n=26, 4.9%) and sinus tenderness when pressure was applied (n=25, 4.7%). Water’s paranasal sinus radiograph was performed in 38 (7.1%) patients. Most preferred antibiotics were amoxicillinclavulanate 167 (78.4%), clarithromycin 18 (8.5%) and cefdinir 13 (6.1%). Symptomatic treatment was rarely prescribed [nasal decongestant (n=38, 17.8%), systemic antihistamines (n=23, 10.8%]. The median treatment period was 10 (3-30) days. Five patients (0.9%) were hospitalized for complications [preseptal cellulitis (n=4), frontal bone osteomyelitis and subdural abscess secondary to facial cellulitis (n=1)]. Patients with preseptal cellulitis were treated with parenteral ampicillin-sulbactam and the patient with osteomyelitis and abscess received ceftriaxone, vancomycin and metronidazole treatment following abscess drainage.

Conclusion: Our results indicate that the diagnosis was substantially based on clinical evaluation even though complete compliance to clinical definitions recommended by current guidelines was lacking, and antibiotic treatment plans were often correct. Moreover, although rare, performance of further investigations and/or prescription of symptomatic treatment were observed. It was aimed to emphasize that clinicians should be encouraged for complete patient records and compliance to current guidelines.

Etik Beyan

-

Destekleyen Kurum

-

Proje Numarası

-

Teşekkür

-

Kaynakça

  • 1. Wald ER, Applegate KE, Bordley C, et al. American Academy of Pediatrics. Clinical practice guideline for the diagnosis and management of acute bacterial sinusitis in children aged 1 to 18 years. Pediatrics. 2013;132:e262-e280.
  • 2. DeMuri G, Wald ER. Acute bacterial sinusitis in children. Pediatr Rev. 2013;34:429-437.
  • 3. Wald ER. Acute bacterial sinusitis in children: Clinical features and diagnosis. Kaplan SL, Wood RA, Isacson GC, ed. UpToDate. Torchia MM: UpToDate Inc https://www.uptodate.com/ (Accessed on May 5, 2019).
  • 4. Chow AW, Benninger MS, Brook I, et al. Infectious Diseases Society of America. IDSA clinical practice guideline for acute bacterial rhinosinusitis in children and adults.Clin Infect Dis. 2012;54:e72-e112.
  • 5. Peters AT, Spector S, Hsu J, et al. Joint Task Force on Practice Parameters, representing the American Academy of Allergy, Asthma and Immunology, the American College of Allergy, Asthma and Immunology, and the Joint Council of Allergy, Asthma and Immunology. Diagnosis and management of rhinosinusitis: a practice parameter update. Ann Allergy Asthma Immunol. 2014;113:347-385.
  • 6. Cherry JD, Kuan EC, Shapiro NL. In: Cherry JD, Harrison G, Kaplan SL, et al, editors. Feigin and Cherry’s Textbook of Pediatric Infectious Diseases. 8th ed, Philadelphia: Elsevier; 2018.p.137.
  • 7. Pappas DE, Hendley JO, Hayden FG, et al. Symptom profile of common colds in school-aged children. Pediatr Infect Dis J. 2008;27:8-11.
  • 8. Wald ER, Milmoe GJ, Bowen A, et al. Acute maxillary sinusitis in children. N Eng J Med. 1981;304:749-54.
  • 9. Tekes A, Palasis S, Durand DJ, et al; Expert Panel on Pediatric Imaging. ACR Appropriateness Criteria® Sinusitis-Child. J Am Coll Radiol. 2018;15:S403-S412.
  • 10. Wald ER. Acute bacterial sinusitis in children: Microbiology and treatment. Kaplan SL, Isacson GC, Wood RA, sec ed. UpToDate. Torchia MM: UpToDate Inc https://www.uptodate.com/ (Accessed on May 5, 2019).
  • 11. Shaikh N, Wald ER. Decongestants, antihistamines and nasal irrigation for acute sinusitis in children. Cochrane Database Syst Rev. 2014;10:CD007909.
  • 12. Gallant JN, Basem JI, Turner JH, et al. Nasal saline irrigation in pediatric rhinosinusitis: A systematic review. Int J Pediatr Otorhinolaryngol. 2018;108:155-162.
  • 13. Germiller JA, Monin DL, Sparano AM, et al. Intracranial complications of sinusitis in children and adolescents and their outcomes. Arch Otolaryngol Head Neck Surg. 2006; 132:969-976.
  • 14. DeMuri GP, Gern JE, Moyer SC, et al. Clinical Features, Virus Identification, and Sinusitis as a Complication of Upper Respiratory Tract Illness in Children Ages 4-7 Years. J Pediatr. 2016;171:133-9.e1.
  • 15. Newton L, Kotowski A, Grinker M, et al. Diagnosis and management of pediatric sinusitis: A survey of primary care, otolaryngology and urgent care providers. Int J Pediatr Otorhinolaryngol. 2018;108:163-167.
  • 16. Kovatch AL, Wald ER, Ledesma-Medina J, et al. Maxillary sinus radiographs in children with nonrespiratory complaints. Pediatrics. 1984;73:306-308.
  • 17. Younis RT, Anand VK, Davidson B. The role of computed tomography and magnetic resonance imaging in patients with sinusitis with complications. Laryngoscope. 2002;112:224-229.
  • 18. Shapiro DJ, Gonzales R, Cabana MD, et al. National trends in visit rates and antibiotic prescribing for children with acute sinusitis. Pediatrics. 2011;127:28-34.
  • 19. Kaur R, Morris M, Pichichero ME. Epidemiology of Acute Otitis Media in the Postpneumococcal Conjugate Vaccine Era Pediatrics. 2017;140.
  • 20. Wald ER, DeMuri GP. Antibiotic Recommendations for Acute Otitis Media and Acute Bacterial Sinusitis: Conundrum No More. Pediatr Infect Dis J. 2018;37:1255-1257.
  • 21. Brook I. Microbiology and antimicrobial treatment of orbital and intracranial complications of sinusitis in children and their management. Int J Pediatr Otorhinolaryngol. 2009;73:1183-1186.
  • 22. Doğru Ü. Preseptal ve Orbital Sellülit. J Pediatr Inf. 2009;3:90-93.
Toplam 22 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Çocuk Sağlığı ve Hastalıkları (Diğer)
Bölüm Makaleler
Yazarlar

Nisa Eda Çullas İlarslan 0000-0002-6365-8059

Proje Numarası -
Yayımlanma Tarihi 2 Ekim 2019
Yayımlandığı Sayı Yıl 2019 Cilt: 72 Sayı: 2

Kaynak Göster

APA Çullas İlarslan, N. E. (2019). Evaluation of Children Diagnosed with Acute Bacterial Sinusitis: Single-center Experience. Ankara Üniversitesi Tıp Fakültesi Mecmuası, 72(2), 134-139. https://doi.org/10.4274/atfm.galenos.2019.84803
AMA Çullas İlarslan NE. Evaluation of Children Diagnosed with Acute Bacterial Sinusitis: Single-center Experience. Ankara Üniversitesi Tıp Fakültesi Mecmuası. Ekim 2019;72(2):134-139. doi:10.4274/atfm.galenos.2019.84803
Chicago Çullas İlarslan, Nisa Eda. “Evaluation of Children Diagnosed With Acute Bacterial Sinusitis: Single-Center Experience”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 72, sy. 2 (Ekim 2019): 134-39. https://doi.org/10.4274/atfm.galenos.2019.84803.
EndNote Çullas İlarslan NE (01 Ekim 2019) Evaluation of Children Diagnosed with Acute Bacterial Sinusitis: Single-center Experience. Ankara Üniversitesi Tıp Fakültesi Mecmuası 72 2 134–139.
IEEE N. E. Çullas İlarslan, “Evaluation of Children Diagnosed with Acute Bacterial Sinusitis: Single-center Experience”, Ankara Üniversitesi Tıp Fakültesi Mecmuası, c. 72, sy. 2, ss. 134–139, 2019, doi: 10.4274/atfm.galenos.2019.84803.
ISNAD Çullas İlarslan, Nisa Eda. “Evaluation of Children Diagnosed With Acute Bacterial Sinusitis: Single-Center Experience”. Ankara Üniversitesi Tıp Fakültesi Mecmuası 72/2 (Ekim 2019), 134-139. https://doi.org/10.4274/atfm.galenos.2019.84803.
JAMA Çullas İlarslan NE. Evaluation of Children Diagnosed with Acute Bacterial Sinusitis: Single-center Experience. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 2019;72:134–139.
MLA Çullas İlarslan, Nisa Eda. “Evaluation of Children Diagnosed With Acute Bacterial Sinusitis: Single-Center Experience”. Ankara Üniversitesi Tıp Fakültesi Mecmuası, c. 72, sy. 2, 2019, ss. 134-9, doi:10.4274/atfm.galenos.2019.84803.
Vancouver Çullas İlarslan NE. Evaluation of Children Diagnosed with Acute Bacterial Sinusitis: Single-center Experience. Ankara Üniversitesi Tıp Fakültesi Mecmuası. 2019;72(2):134-9.