Derleme
BibTex RIS Kaynak Göster

Murraya koenigii (köri yaprağı) fitokimyasal bileşimi üzerine derinlemesine bir inceleme: Aktif bileşenler ve terapötik etkileri

Yıl 2025, Cilt: 6 Sayı: 1, 40 - 59, 30.04.2025

Pranjal Sachan , Prachi Shrivastava , Akansha Kushwaha Kris Jain Laxmi Kant

https://doi.org/10.53445/batd.1581503

Öz

Yaygın şekilde “köri yaprağı” olarak bilinen Murraya koenigii, Güney Asya'ya özgü olup, çeşitli yemeklerdeki lezzeti ve kokusuyla ünlüdür. Bitkisel ilaçlar, uygun maliyetleri ve minimal yan etkilerinden ötürü yüzyıllardır çeşitli hastalıkların tedavisinde kullanılmaktadırlar. Geleneksel ayurveda tıbbında köri yaprağı önemli bir rol oynar. Bu küçük yaprak döken çalı, besleyici ve tedavi edici nitelikler de dahil olmak üzere, geleceğin endüstriyel ürününün tüm özelliklerine sahiptir. Araştırmalar, Murraya koenigii’nin özellikle yapraklarında, gövdelerinde, kabuğunda ve yağında antibakteriyel, antifungal ve antiprotozoal aktivitelere sahip olduğunu göstermektedir. Bitkinin uçucu yağı ve ekstreleri, antifungal ve antibakteriyel potansiyellere sahiptir. Köri yaprağı, kanser progresyonunda bilinen bir faktör olan oksidatif stresi azaltmaya yardımcı, güçlü antioksidan özelliklerine potansiyel olarak atfedilen antikanser etkileri sergileyebilir. Bitki, yağ asitleri, mineraller, vitaminler, karbonhidratlar ve proteinler içerdiğinden besleyici olma potansiyeline sahiptir. Bitkinin tamamı stomaşik ve tonik özellikleri için kullanılır. Mevcut çalışmanın amacı köri yaprağının küresel kategorizasyonunu, kökenini, morfolojik özelliklerini ve geleneksel kullanımını değerlendirmektir.

Anahtar Kelimeler

Murraya koenigii köri yaprağı fitokimyasal bileşim biyoaktif bileşenler antioksidan özellikler yapraklar ekstreler bitkisel bileşenler terapötik uygulamalar

Kaynakça

  • Ajay, S., Rahul, S., Sumit, G., Paras, M., Mishra, A., & Gaurav, A. (2011). Comprehensive review: Murraya koenigii Linn. Asian J Pharm Life Sci, 1(4).
  • Al Harbi, H., Irfan, U. M., & Ali, S. (2016). The antibacterial effect of curry leaves (Murraya koenigii). EJPMR, 3, 382-387.
  • Balakrishnan, R., Vijayraja, D., Jo, S. H., Ganesan, P., Su-Kim, I., & Choi, D. K. (2020). Medicinal profile, phytochemistry, and pharmacological activities of Murraya koenigii and its primary bioactive compounds. Antioxidants, 9(2), 101. https://doi.org/10.3390/antiox9020101
  • Beenakumari, K. S. (2011). Inhibitory effects of Murraya koenigii (curry leaf) leaf extract on the corrosion of mild steel in 1 M HCl. Green Chemistry Letters and Reviews, 4(2), 117-120. https://doi.org/10.1080/17518253.2010.514866
  • Bhandari, P. (2012). Curry leaf (Murraya koenigii) or Cure leaf: Review of its curative properties. Journal of medical nutrition and nutraceuticals, 1(2), 92.
  • Bhusal, D., & Thakur, D. P. (2021). Curry Leaf: A Review. Reviews in Food and Agriculture, 2(1), 36-38. https://doi.org/10.26480/rfna.01.2021.36.38
  • Chauhan, B., Dedania, J., & Mashru, R. C. (2017). Review on Murraya koenigii: versatile role in management of human health. World Journal of Pharmacy And Pharmaceutical Sciences, 6(3), 476-493.
  • Chellappandian, M., Vasantha-Srinivasan, P., Han, Y. S., Senthil-Nathan, S., Karthi, S., Kalaivani, K., Park, K. B., Veerabahu, C., Radhakrishnan, N., Raghuraman, P., Govindharaj, G., & Almutairi, B. O. (2024). Essential oils from Murraya koenigii (L.) Spreng. and their phytochemicals as an environmental-friendly agent against pests of medical importance. Biocatalysis and Agricultural Biotechnology, 58, 103161. https://doi.org/10.1016/j.bcab.2024.103161
  • Chelliah, R., Ramakrishnan, S. R., Premkumar, D., & Antony, U. (2016). Bio-fortification and shelf-life extension of idli batter using curry leaves (Murraya koenigii). Journal of food science and technology, 53, 2851-2862. https://doi.org/10.1007/s13197-016-2264-2
  • Choo, C. O., Chua, B. L., Figiel, A., Jałoszyński, K., Wojdyło, A., Szumny, A., Łyczko, J., & Chong, C. H. (2020). Hybrid Drying of Murraya koenigii Leaves: Energy Consumption, Antioxidant Capacity, Profiling of Volatile Compounds and Quality Studies. Processes, 8(2), 240. https://doi.org/10.3390/pr8020240
  • Chowdhury, J. U., Bhuiyan, M. N. I., & Yusuf, M. (2008). Chemical composition of the leaf essential oils of Murraya koenigii (L.) Spreng and Murraya paniculata (L.) Jack. Bangladesh Journal of Pharmacology, 3(2), 59-63. https://doi.org/10.3329/bjp.v3i2.841
  • Darvekar, V. M., Patil, V. R., & Choudhari, A. B. (2011). Anti-inflammatory activity of Murraya koenigii Spreng on experimental animals. J Nat Prod Plant Resour, 1(1), 65-69.
  • Das, A. K., Rajkumar, V., & Dwivedi, D. K. (2011). Antioxidant effect of curry leaf (Murraya koenigii) powder on quality of ground and cooked goat meat. International Food Research Journal, 18(2).
  • Dasgupta, T., Rao, A. R., & Yadava, P. K. (2003). Chemomodulatory action of curry leaf (Murraya koenigii) extract on hepatic and extrahepatic xenobiotic metabolising enzymes, antioxidant levels, lipid peroxidation, skin and forestomach papillomagenesis. Nutrition research, 23(10), 1427-1446. https://doi.org/10.1016/S0271-5317(03)00136-2
  • Datta, H. S., Bora, D., Purkayastha, M. D., Choudhury, M., & Neog, M. (2023). Murraya koenigii (L.) Spreng. In Himalayan Fruits and Berries (pp. 271-287). Academic Press. https://doi.org/10.1016/B978-0-323-85591-4.00044-1
  • Debosree, G., Syed, B. F., Elina, M., Monalisa, D., & Debasish, B. (2012). Protective effect of aqueous leaf extract of Murraya koenigi against lead induced oxidative stress in rat liver, heart and kidney: a dose response study. Asian J Pharm Clin Res, 5(Suppl 4), 54-58.
  • Dwivedi, J., Kumar, P., Sachan, P., Singh, C., Saxena, B., Wal, A., & Wal, P. (2025). Phyto-pharmacological Potential of Aegle marmelos (L.) for Neurological Disorders: Progress and Prospects. Recent Patents on Food, Nutrition & Agriculture, 16(1), 12-30. https://doi.org/10.2174/012772574X289517240222045916
  • Dwivedi, J., Sachan, P., & Wal, P. (2024). A Mechanistic Approach on Structural, Analytical and Pharmacological Potential of Beta-sitosterol: A Promising Nutraceutical. Current Nutrition & Food Science, 20(8), 932-951. https://doi.org/10.2174/0115734013245468230927042947
  • Dwivedi, J., Sachan, P., Wal, P., Dwivedi, S., Sharma, M. C., & Rao, S. P. (2024). Detailed review on phytosomal formulation attenuating new pharmacological therapies. Advances in Traditional Medicine, 24(3), 659-684. https://doi.org/10.1007/s13596-023-00712-3
  • El‐Shiekh, R. A., Elshimy, R., Mandour, A. A., Kassem, H. A. H., Khaleel, A. E., Alseekh, S., Fernie, A. R., & Salem, M. A. (2024). Phytochemical characterisation of leaves and stems of Murraya koenigii (L.) Sprengel and Murraya paniculata (L.) Jack and their antibacterial activity against multidrug‐resistant Acinetobacter baumannii bacterial infection. International Journal of Food Science & Technology, 59(10), 7998–8010. https://doi.org/10.1111/ijfs.17032
  • El-Shiekh, R. A., Kassem, H. A., Khaleel, A. E., & Abd El-Mageed, M. M. (2024). Anticholinesterases activity of Murraya koenigii (L.) Spreng. and Murraya paniculata (L.) Jacq. essential oils with GC/MS analysis and molecular docking. Natural Product Research, 38(12), 2155-2159. https://doi.org/10.1080/14786419.2023.2241150
  • Elumalai, K., Velmurugan, S., Ravi, S., Kathiravan, V., & Ashokkumar, S. (2015). Bio-fabrication of zinc oxide nanoparticles using leaf extract of curry leaf (Murraya koenigii) and its antimicrobial activities. Materials Science in Semiconductor Processing, 34, 365-372. https://doi.org/10.1016/j.mssp.2015.01.048
  • Gahlawat, D. K., Jakhar, S., & Dahiya, P. (2014). Murraya koenigii (L.) Spreng: an ethnobotanical, phytochemical and pharmacological review. Journal of Pharmacognosy and Phytochemistry, 3(3), 109-119.
  • Gahtori, K., Aggarwal, C., Tyagi, M., Bajpai, A. B., Srivastava, N., Singh, S., Singh, S., & Gaurav, N. (2022). Review on Murraya koenigii: Dietary Supplements and Highly Prosperous Plants of Pharmacological Value. The Scientific Temper, 13(1), 108–114.
  • Ghasemzadeh, A., Jaafar, H. Z., Rahmat, A., & Devarajan, T. (2014). Evaluation of bioactive compounds, pharmaceutical quality, and anticancer activity of curry leaf (Murraya koenigii L.). Evidence‐Based Complementary and Alternative Medicine, 2014(1), 873803. https://doi.org/10.1155/2014/873803
  • Ghimire, A., & Magar, N. (2018). Thin Layer Drying Kinetics Modelling of Curry Leaves (Murraya koenigii L.) in Cabinet Dryer. Himalayan Journal of Science and Technology, 2, 53-58. https://doi.org/10.3126/hijost.v2i0.25844
  • Goel, A., Sharma, A., & Kulshrestha, S. (2020). A phytopharmacological review on Murraya koenigii: an important medicinal plant. Int J Pharm Sci Rev Res, 62(2), 113-119.
  • Goyal, P., Chhabra, R., & Vij, L. (2020). Ethnobotany, Phytochemical, Pharmacological Potentials of Murraya koenigii, and Its Health Benefits–A Review. Current Journal of Applied Science and Technology, 39(26), 29-38. https://doi.org/10.9734/CJAST/2020/v39i2630902
  • Guo, Y., Ma, A., Wang, X., Yang, C., Chen, X., Li, G., & Qiu, F. (2022). Research progress on the antiviral activities of natural products and their derivatives: Structure–activity relationships. Frontiers in Chemistry, 10, 1005360. https://doi.org/10.3389/fchem.2022.1005360
  • Handral, H. K., Pandith, A., & Shruthi, S. D. (2012). A review on Murraya koenigii: multipotential medicinal plant. Asian Journal of pharmaceutical and clinical research, 5(4), 5-14.
  • Hema, R., Kumaravel, S., & Alagusundaram, K. (2011). GC/MS determination of bioactive components of Murraya koenigii. Journal of American Science, 7(1), 80-83.
  • Indhumathi, K., Vidhya, D., Gurusamy, K., Paramaguru, P., & Santhi, V. P. (2020). Genetic Variability Studies and Character Association for Yield and Quality Traits in Curry leaf (Murraya koengii (L.) Spreng.). Chemical Engineering, 1, 164.
  • Igara, C. E., Omoboyowa, D. A., Ahuchaogu, A. A., Orji, N. U., & Ndukwe, M. K. (2016). Phytochemical and nutritional profile of Murraya koenigii (Linn) Spreng leaf. Journal of Pharmacognosy and Phytochemistry, 5(5), 07-09.
  • Iqbal, Z., Mehmood, H. K., Hussain, M., Mehmood, M. H. R., & Choudhry, M. N. (2017). Antioxidant activity of essential oil from the leaves and stems of Murraya koenigii. World Journal of Pharmaceutical Research, 6(7), 267-273.
  • Iyer, D., & Devi, U. (2008). Phyto-pharmacology of Murraya koenigii (L.). Pharmacognosy Reviews, 2(3), 180.
  • Jachak, S. M., Thakur, M. S., Ahirrao, P., & Goyal, A. (2024). Murraya koenigii (L.) Spreng. as a Natural Intervention for Diabesity: A Review. Current Pharmaceutical Design, 30(41), 3255-3275. https://doi.org/10.2174/0113816128304471240801183021
  • Jain, M., Gilhotra, R., Singh, R. P., & Mittal, J. (2017). Curry leaf (Murraya koenigii): A spice with medicinal property. MOJ Biol Med, 2(3), 236-256. https://doi.org/10.15406/mojbm.2017.02.00050
  • Joseph, S., & Peter, K. V. (1985). Curry leaf (Murraya koenigii), perennial, nutritious, leafy vegetable. Economic Botany, 39, 68-73. https://doi.org/10.1007/BF02861176
  • Khan, B. A., Abraham, A., & Leelamma, S. (1996). Role of Murraya koenigii (curry leaf) and Brassica juncea (Mustard) in lipid peroxidation. Indian Journal of Physiology and Pharmacology, 40, 155-158.
  • Khurana, A., Sikha, M. S., Ramesh, K., Venkatesh, P., & Godugu, C. (2019). Modulation of cerulein‐induced pancreatic inflammation by hydroalcoholic extract of curry leaf (Murraya koenigii). Phytotherapy Research, 33(5), 1510-1525. https://doi.org/10.1002/ptr.6344
  • Kundu, P., Sharma, P., Mahato, R., Saha, M., Das, S., & Ghosh, P. (2020). A brief review for the development of bio-nanoparticles using some important Indian ethnomedicinal plants. Journal of Medicinal Plant Studies, 8(6), 26-33. https://doi.org/10.22271/plants.2020.v8.i6a.1226
  • Kureel, S. P., Kapil, R. S., & Popli, S. P. (1970). Two novel alkaloids from Murraya koenigii Spreng: mahanimbicine and bicyclomahanimbicine. Chemistry & industry, 29, 958.
  • Kushwaha, A., Shrivastava, P., Sachan, P., Gupta, S., & Goswami, M. (2024). Understanding the COVID-19 Pandemic: An Overview of Ayurvedic and Traditional Formulations used for COVID-19. Journal of Research in Complementary Medicine, 1(1), 19-37. http://dx.doi.org/10.5455/JRCM.20240205070319
  • Lawal, H., Atiku, M. K., Khelpai, D. G., & Wannang, N. N. (2008). Hypoglycaemic and hypolipidaemic effects of the aqueous leaf extract of Murraya koenigii in normal and alloxan–diabetic rats. Nigerian Journal of Physiological Sciences, 23(1-2). https://doi.org/10.4314/njps.v23i1-2.54919
  • Malode, G. P., Parbat, A. Y., Shaikh, A. R., Panchale, W. A., Manwar, J. V., & Bakal, R. L. (2021). Phytochemistry, pharmacology and botanical aspects of Murraya Koenigii in the search for molecules with bioactive potential-A review. GSC Advanced Research and Reviews, 6(3), 143-155. https://doi.org/10.30574/gscarr.2021.6.3.0055
  • Manandhar, D. (2021). Review Article on Status of Soybean Production in Nepal. Reviews in Food and Agriculture (RFNA), 2(2), 31-33.
  • Mandal, S., Nayak, A., Kar, M., Banerjee, S. K., Das, A., Upadhyay, S. N., Singh, R. K., Banerji, A., & Banerji, J. (2010). Antidiarrhoeal activity of carbazole alkaloids from Murraya koenigii Spreng (Rutaceae) seeds. Fitoterapia, 81(1), 72–74. https://doi.org/10.1016/j.fitote.2009.08.016
  • Manna, P., Sinha, M., & Sil, P. C. (2008). Amelioration of cadmium-induced cardiac impairment by taurine. Chemico-biological interactions, 174(2), 88-97. https://doi.org/10.1016/j.cbi.2008.05.005
  • Mitra, E., Ghosh, A. K., Ghosh, D., Mukherjee, D., Chattopadhyay, A., Dutta, S., Pattari, S. K., & Bandyopadhyay, D. (2012). Protective effect of aqueous Curry leaf (Murraya koenigii) extract against cadmium-induced oxidative stress in rat heart. Food and chemical toxicology, 50(5), 1340–1353. https://doi.org/10.1016/j.fct.2012.01.048
  • Nagappan, T., Ramasamy, P., Wahid, M. E. A., Segaran, T. C., & Vairappan, C. S. (2011). Biological activity of carbazole alkaloids and essential oil of Murraya koenigii against antibiotic resistant microbes and cancer cell lines. Molecules, 16(11), 9651-9664. https://doi.org/10.3390/molecules16119651
  • Nigam, L. (2023). Curry Leaf (Murraya koenigii): A Wonder Spice with Medicinal Value. Journal of Advancement in Pharmacognosy, 4(1).
  • Ningappa, M. B., Dhananjaya, B. L., Dinesha, R., Harsha, R., & Srinivas, L. (2010). Potent antibacterial property of APC protein from curry leaves (Murraya koenigii L.). Food chemistry, 118(3), 747-750. https://doi.org/10.1016/j.foodchem.2009.05.059
  • Ningappa, M. B., Dinesha, R., & Srinivas, L. (2008). Antioxidant and free radical scavenging activities of polyphenol-enriched curry leaf (Murraya koenigii L.) extracts. Food chemistry, 106(2), 720-728. https://doi.org/10.1016/j.foodchem.2007.06.057
  • Ningappa, M. B., & Srinivas, L. (2008). Purification and characterization of∼ 35 kDa antioxidant protein from curry leaves (Murraya koenigii L.). Toxicology in vitro, 22(3), 699-709. https://doi.org/10.1016/j.tiv.2007.11.009
  • Prajapati, N. D., Purohit, S. S., Sharma, A. K., & Kumar, T. (2003). A handbook of medicinal plants: A complete source book (pp. 554-554).
  • Raghavan, R. S. (1957, June). Chromosome numbers in Indian medicinal plants. In Proceedings/Indian Academy of Sciences (Vol. 45, No. 6, pp. 294-298). New Delhi: Springer India. https://doi.org/10.1007/BF03051030
  • Raina, V. K., Lal, R. K., Tripathi, S., Khan, M., Syamasundar, K. V., & Srivastava, S. K. (2002). Essential oil composition of genetically diverse stocks of Murraya koenigii from India. Flavour and fragrance journal, 17(2), 144-146. https://doi.org/10.1002/ffj.1058
  • Rajendran, M. P., Pallaiyan, B. B., & Selvaraj, N. (2014). Chemical composition, antibacterial and antioxidant profile of essential oil from Murraya koenigii (L.) leaves. Avicenna journal of phytomedicine, 4(3), 200. PMCID: PMC4104627
  • Ramnath, G. M., Jayaraman, S., Thirugnanasampandan, R., Gunasekaran, B., & Gopalakrishnan, A. (2023). Chemical composition analysis and evaluation of antioxidant, antiacetylcholinesterase and cytotoxicity of Murraya koenigii (l.) Spreng fruit oil. Journal of microbiology, biotechnology and food sciences, 13(3), e6135-e6135.
  • Rana, V. S., Juyal, J. P., & Blazquez, M. A. (2004). Chemical constituents of the volatile oil of Murraya koenigii leaves. International Journal of Aromatherapy, 14(1), 23-25. https://doi.org/10.1016/j.ijat.2003.12.007
  • Rao, B. R., Rajput, D. K., & Mallavarapu, G. R. (2011). Chemical diversity in curry leaf (Murraya koenigii) essential oils. Food Chemistry, 126(3), 989-994. https://doi.org/10.1016/j.foodchem.2010.11.106
  • Rao, L. J. M., Ramalakshmi, K., Borse, B. B., & Raghavan, B. (2007). Antioxidant and radical-scavenging carbazole alkaloids from the oleoresin of curry leaf (Murraya koenigii Spreng.). Food Chemistry, 100(2), 742-747. https://doi.org/10.1016/j.foodchem.2005.10.033
  • Rastogi, R. M. (1990). Compendium of Indian medicinal plants. Central Drug Research Institute, Lucknow, India, 1, 388-389.
  • Sachan, P., Shrivastava, P., & Goswami, M. (2024). Revolutionizing the Potential of Probiotics an Evidence-Based Review. Journal of Ravishankar University, Part-B Science, 37(2). https://doi.org/10.52228/JRUB.2024-37-2-7
  • Sachan, P., Shrivastava, P., & Goswami, M. (2025). Unleashing Translational Opportunities of Loco-Regional Drug Delivery to Treat Malignancy. Asian Pacific Journal of Cancer Biology, 10(1), 213-228.
  • Saini, S. C., & Reddy, G. B. S. (2015). A review on curry leaves (Murraya koenigii): Versatile multi-potential medicinal plant. Am J Phytomed Clin Ther, 3(4), 363-368.
  • Samanta, S. K., Kandimalla, R., Gogoi, B., Dutta, K. N., Choudhury, P., Deb, P. K., Devi, R., Pal, B. C., & Talukdar, N. C. (2018). Phytochemical portfolio and anticancer activity of Murraya koenigii and its primary active component, mahanine. Pharmacological research, 129, 227–236. https://doi.org/10.1016/j.phrs.2017.11.024
  • Sarswat, S., & Yadav, D. S. (2023). A Marvel Versatile, Multipotential Plant Murraya Koenigii: A Review. Knowledgeable Research: A Multidisciplinary Peer-Reviewd Refereed Journal, 1(12), 26-34.
  • Sasidharan, I., & Menon, A. N. (2011). Effects of temperature and solvent on antioxidant properties of curry leaf (Murraya koenigii L.). Journal of food science and technology, 48, 366-370. https://doi.org/10.1007/s13197-010-0134-x
  • Sharma, M., Urvashi, Gupta, H., Anmol, Sharma, U., & Reddy, S. E. (2024). Chemical Composition and Insecticidal Potential of Essential Oil from Murraya koenigii (L.) Obtained by Natural Deep Eutectic Solvents. Neotropical Entomology, 1-14. https://doi.org/10.1007/s13744-024-01207-9
  • Sharma, R., & Kumar, U. (2019). Exploration and phytochemical estimation of Murraya koenigii leaves for pharmaceutical applications. Asian Journal of Pharmaceutical Research, 9(3), 159-168.
  • Singh, S., Ahuja, A., Murti, Y., & Khaliq, A. (2023). Phyto‐Pharmacological Review on Murraya koenigii (L.) Spreng: As an Indigenous Plant of India with High Medicinal Potential. Chemistry & Biodiversity, 20(7), e202300483. https://doi.org/10.1002/cbdv.202300483
  • Singh, S., More, P. K., & Mohan, S. M. (2014). Curry leaves (Murraya koenigii Linn. Sprengal)-a mircale plant. Indian Journal of Scientific Research, 4(1), 46-52.
  • Soundappan, K., Bajaj, R., Vaidya, B. N., & Joshee, N. (2018). Anatomical and biochemical investigations on medicinal tree Murraya koenigii Spreng. Journal of Biotech Research, 9, 70-78.
  • Syaifurrisal, A., Suciyono, S., Santanumurti, M. B., Prajitno, A., Fadjar, M., Riyadi, F. M., Fauziyyah, A. I., Pariawan, A., & Abualreesh, M. H. (2024). Effect of Curry Leaf (Murraya koenigii) as Edwardsiellosis Treatment on Gourami Fish (Osphronemus goramy). Aquatic Sciences and Engineering, 39(3), 179-188. https://doi.org/10.26650/ASE20231367517
  • Tripathi, Y. C., Anjum, N., & Rana, A. (2018). Chemical composition and in vitro antifungal and antioxidant activities of essential oil from Murraya koenigii (L.) Spreng. Leaves. Asian Journal of Biomedical and Pharmaceutical Sciences, 8(65), 6-13.
  • Uraku, A. J., & Nwankwo, V. O. (2015). Phytochemical and nutritional composition analysis of Murraya koenigii Linn leaves. British Journal of Pharmaceutical Research, 6(3), 174-180. https://doi.org/10.9734/BJPR/2015/15595
  • Verma, D., Macwan, D., Patel, J. D., Parmar, S. R., & Patel, H. V. (2022). Herbs that heal: Role of traditional herbal remedies as an immunity booster and effective against the infectious and systemic diseases. Annals of Phytomedicine, 11(2), 7-16. http://dx.doi.org/10.54085/ap.2022.11.2.2
  • Verma, R. S., Chauhan, A., Padalia, R. C., Jat, S. K., Thul, S., & Sundaresan, V. (2013). Phytochemical diversity of Murraya koenigii (L.) Spreng. from western Himalaya. Chemistry & Biodiversity, 10(4), 628-641. https://doi.org/10.1002/cbdv.201200054
  • Visakh, N. U., Pathrose, B., & Narayanankutty, A. (2023). Characterization of secondary metabolites from the leaves of curry leaf (Murraya koenigii L.) essential oils with insecticidal activities against stored product insects. Biocatalysis and Agricultural Biotechnology, 54, 102973. https://doi.org/10.1016/j.bcab.2023.102973
  • Viswanathan, K., Ashok, B., & Pugazhendhi, A. (2020). Comprehensive study of engine characteristics of novel biodiesel from curry leaf (Murraya koenigii) oil in ceramic layered diesel engine. Fuel, 280, 118586. https://doi.org/10.1016/j.fuel.2020.118586
  • Wee, A. S., Thew, H. Y., Liew, S. Y., Tan, W. N., & Khaw, K. Y. (2024). Anti-cholinesterase profile of Murraya koenigii (L.) Spreng essential oil and its chemical constituents. Journal of Essential Oil Bearing Plants, 1-11. https://doi.org/10.1080/0972060X.2024.2398676
  • Xie, J. T., Chang, W. T., Wang, C. Z., Mehendale, S. R., Li, J., Ambihaipahar, R., Ambihaipahar, U., Fong, H. H., & Yuan, C. S. (2006). Curry leaf (Murraya koenigii Spreng.) reduces blood cholesterol and glucose levels in ob/ob mice. The American journal of Chinese medicine, 34(2), 279–284. https://doi.org/10.1142/S0192415X06003825
  • Yankuzo, H., Ahmed, Q. U., Santosa, R. I., Akter, S. F. U., & Talib, N. A. (2011). Beneficial effect of the leaves of Murraya koenigii (Linn.) Spreng (Rutaceae) on diabetes-induced renal damage in vivo. Journal of Ethnopharmacology, 135(1), 88-94. https://doi.org/10.1016/j.jep.2011.02.020
  • You, C., Zhang, W., Guo, S., Wang, C., Yang, K., Liang, J., Wang, Y., Geng, Z., Du, S., & Deng, Z. (2015). Chemical composition of essential oils extracted from six Murraya species and their repellent activity against Tribolium castaneum. Industrial Crops and Products, 76, 681–687. https://doi.org/10.1016/j.indcrop.2015.07.044
  • Zou, Q., Huang, Y., Zhang, W., Lu, C., & Yuan, J. (2023). A comprehensive review of the pharmacology, chemistry, traditional uses and quality control of star anise (Illicium verum Hook. F.): An aromatic medicinal plant. Molecules, 28(21), 7378. https://doi.org/10.3390/molecules28217378

A deep dive into the phytochemical composition of Murraya koenigii (curry leaf): Active compounds and their therapeutic implications

Yıl 2025, Cilt: 6 Sayı: 1, 40 - 59, 30.04.2025

Pranjal Sachan , Prachi Shrivastava , Akansha Kushwaha Kris Jain Laxmi Kant

https://doi.org/10.53445/batd.1581503

Öz

Murraya koenigii, commonly known as curry leaf, is native to South Asia and is renowned for its flavor and fragrance in a variety of dishes. Herbal medicines have been used for centuries to treat various illnesses due to their affordability and minimal side effects. In traditional ayurvedic medicine, curry leaf plays a major role. This small deciduous shrub has all the makings of a future industrial product, including nutritional and therapeutic qualities. Research indicates that Murraya koenigii has antibacterial, antifungal, and antiprotozoal activities, particularly in its leaves, stems, bark, and oil. The plant’s essential oil and extracts have antifungal and antibacterial potentials. Curry leaf may exhibit anticancer effects, potentially attributed to their potent antioxidant properties that help reduce oxidative stress, a known factor in cancer progression. The plant has the potential to be nutritious since it contains fatty acids, minerals, vitamins, carbohydrates and proteins. The whole plant is utilised for its stomachic and tonic qualities. The current study aims to evaluate the global categorisation, origin, morphological characteristics, and traditional uses of curry leaf.

Anahtar Kelimeler

Murraya koenigii curry leaf phytochemical composition bioactive compounds antioxidant properties leaves extracts phytoconstituents therapeutic applications

Kaynakça

  • Ajay, S., Rahul, S., Sumit, G., Paras, M., Mishra, A., & Gaurav, A. (2011). Comprehensive review: Murraya koenigii Linn. Asian J Pharm Life Sci, 1(4).
  • Al Harbi, H., Irfan, U. M., & Ali, S. (2016). The antibacterial effect of curry leaves (Murraya koenigii). EJPMR, 3, 382-387.
  • Balakrishnan, R., Vijayraja, D., Jo, S. H., Ganesan, P., Su-Kim, I., & Choi, D. K. (2020). Medicinal profile, phytochemistry, and pharmacological activities of Murraya koenigii and its primary bioactive compounds. Antioxidants, 9(2), 101. https://doi.org/10.3390/antiox9020101
  • Beenakumari, K. S. (2011). Inhibitory effects of Murraya koenigii (curry leaf) leaf extract on the corrosion of mild steel in 1 M HCl. Green Chemistry Letters and Reviews, 4(2), 117-120. https://doi.org/10.1080/17518253.2010.514866
  • Bhandari, P. (2012). Curry leaf (Murraya koenigii) or Cure leaf: Review of its curative properties. Journal of medical nutrition and nutraceuticals, 1(2), 92.
  • Bhusal, D., & Thakur, D. P. (2021). Curry Leaf: A Review. Reviews in Food and Agriculture, 2(1), 36-38. https://doi.org/10.26480/rfna.01.2021.36.38
  • Chauhan, B., Dedania, J., & Mashru, R. C. (2017). Review on Murraya koenigii: versatile role in management of human health. World Journal of Pharmacy And Pharmaceutical Sciences, 6(3), 476-493.
  • Chellappandian, M., Vasantha-Srinivasan, P., Han, Y. S., Senthil-Nathan, S., Karthi, S., Kalaivani, K., Park, K. B., Veerabahu, C., Radhakrishnan, N., Raghuraman, P., Govindharaj, G., & Almutairi, B. O. (2024). Essential oils from Murraya koenigii (L.) Spreng. and their phytochemicals as an environmental-friendly agent against pests of medical importance. Biocatalysis and Agricultural Biotechnology, 58, 103161. https://doi.org/10.1016/j.bcab.2024.103161
  • Chelliah, R., Ramakrishnan, S. R., Premkumar, D., & Antony, U. (2016). Bio-fortification and shelf-life extension of idli batter using curry leaves (Murraya koenigii). Journal of food science and technology, 53, 2851-2862. https://doi.org/10.1007/s13197-016-2264-2
  • Choo, C. O., Chua, B. L., Figiel, A., Jałoszyński, K., Wojdyło, A., Szumny, A., Łyczko, J., & Chong, C. H. (2020). Hybrid Drying of Murraya koenigii Leaves: Energy Consumption, Antioxidant Capacity, Profiling of Volatile Compounds and Quality Studies. Processes, 8(2), 240. https://doi.org/10.3390/pr8020240
  • Chowdhury, J. U., Bhuiyan, M. N. I., & Yusuf, M. (2008). Chemical composition of the leaf essential oils of Murraya koenigii (L.) Spreng and Murraya paniculata (L.) Jack. Bangladesh Journal of Pharmacology, 3(2), 59-63. https://doi.org/10.3329/bjp.v3i2.841
  • Darvekar, V. M., Patil, V. R., & Choudhari, A. B. (2011). Anti-inflammatory activity of Murraya koenigii Spreng on experimental animals. J Nat Prod Plant Resour, 1(1), 65-69.
  • Das, A. K., Rajkumar, V., & Dwivedi, D. K. (2011). Antioxidant effect of curry leaf (Murraya koenigii) powder on quality of ground and cooked goat meat. International Food Research Journal, 18(2).
  • Dasgupta, T., Rao, A. R., & Yadava, P. K. (2003). Chemomodulatory action of curry leaf (Murraya koenigii) extract on hepatic and extrahepatic xenobiotic metabolising enzymes, antioxidant levels, lipid peroxidation, skin and forestomach papillomagenesis. Nutrition research, 23(10), 1427-1446. https://doi.org/10.1016/S0271-5317(03)00136-2
  • Datta, H. S., Bora, D., Purkayastha, M. D., Choudhury, M., & Neog, M. (2023). Murraya koenigii (L.) Spreng. In Himalayan Fruits and Berries (pp. 271-287). Academic Press. https://doi.org/10.1016/B978-0-323-85591-4.00044-1
  • Debosree, G., Syed, B. F., Elina, M., Monalisa, D., & Debasish, B. (2012). Protective effect of aqueous leaf extract of Murraya koenigi against lead induced oxidative stress in rat liver, heart and kidney: a dose response study. Asian J Pharm Clin Res, 5(Suppl 4), 54-58.
  • Dwivedi, J., Kumar, P., Sachan, P., Singh, C., Saxena, B., Wal, A., & Wal, P. (2025). Phyto-pharmacological Potential of Aegle marmelos (L.) for Neurological Disorders: Progress and Prospects. Recent Patents on Food, Nutrition & Agriculture, 16(1), 12-30. https://doi.org/10.2174/012772574X289517240222045916
  • Dwivedi, J., Sachan, P., & Wal, P. (2024). A Mechanistic Approach on Structural, Analytical and Pharmacological Potential of Beta-sitosterol: A Promising Nutraceutical. Current Nutrition & Food Science, 20(8), 932-951. https://doi.org/10.2174/0115734013245468230927042947
  • Dwivedi, J., Sachan, P., Wal, P., Dwivedi, S., Sharma, M. C., & Rao, S. P. (2024). Detailed review on phytosomal formulation attenuating new pharmacological therapies. Advances in Traditional Medicine, 24(3), 659-684. https://doi.org/10.1007/s13596-023-00712-3
  • El‐Shiekh, R. A., Elshimy, R., Mandour, A. A., Kassem, H. A. H., Khaleel, A. E., Alseekh, S., Fernie, A. R., & Salem, M. A. (2024). Phytochemical characterisation of leaves and stems of Murraya koenigii (L.) Sprengel and Murraya paniculata (L.) Jack and their antibacterial activity against multidrug‐resistant Acinetobacter baumannii bacterial infection. International Journal of Food Science & Technology, 59(10), 7998–8010. https://doi.org/10.1111/ijfs.17032
  • El-Shiekh, R. A., Kassem, H. A., Khaleel, A. E., & Abd El-Mageed, M. M. (2024). Anticholinesterases activity of Murraya koenigii (L.) Spreng. and Murraya paniculata (L.) Jacq. essential oils with GC/MS analysis and molecular docking. Natural Product Research, 38(12), 2155-2159. https://doi.org/10.1080/14786419.2023.2241150
  • Elumalai, K., Velmurugan, S., Ravi, S., Kathiravan, V., & Ashokkumar, S. (2015). Bio-fabrication of zinc oxide nanoparticles using leaf extract of curry leaf (Murraya koenigii) and its antimicrobial activities. Materials Science in Semiconductor Processing, 34, 365-372. https://doi.org/10.1016/j.mssp.2015.01.048
  • Gahlawat, D. K., Jakhar, S., & Dahiya, P. (2014). Murraya koenigii (L.) Spreng: an ethnobotanical, phytochemical and pharmacological review. Journal of Pharmacognosy and Phytochemistry, 3(3), 109-119.
  • Gahtori, K., Aggarwal, C., Tyagi, M., Bajpai, A. B., Srivastava, N., Singh, S., Singh, S., & Gaurav, N. (2022). Review on Murraya koenigii: Dietary Supplements and Highly Prosperous Plants of Pharmacological Value. The Scientific Temper, 13(1), 108–114.
  • Ghasemzadeh, A., Jaafar, H. Z., Rahmat, A., & Devarajan, T. (2014). Evaluation of bioactive compounds, pharmaceutical quality, and anticancer activity of curry leaf (Murraya koenigii L.). Evidence‐Based Complementary and Alternative Medicine, 2014(1), 873803. https://doi.org/10.1155/2014/873803
  • Ghimire, A., & Magar, N. (2018). Thin Layer Drying Kinetics Modelling of Curry Leaves (Murraya koenigii L.) in Cabinet Dryer. Himalayan Journal of Science and Technology, 2, 53-58. https://doi.org/10.3126/hijost.v2i0.25844
  • Goel, A., Sharma, A., & Kulshrestha, S. (2020). A phytopharmacological review on Murraya koenigii: an important medicinal plant. Int J Pharm Sci Rev Res, 62(2), 113-119.
  • Goyal, P., Chhabra, R., & Vij, L. (2020). Ethnobotany, Phytochemical, Pharmacological Potentials of Murraya koenigii, and Its Health Benefits–A Review. Current Journal of Applied Science and Technology, 39(26), 29-38. https://doi.org/10.9734/CJAST/2020/v39i2630902
  • Guo, Y., Ma, A., Wang, X., Yang, C., Chen, X., Li, G., & Qiu, F. (2022). Research progress on the antiviral activities of natural products and their derivatives: Structure–activity relationships. Frontiers in Chemistry, 10, 1005360. https://doi.org/10.3389/fchem.2022.1005360
  • Handral, H. K., Pandith, A., & Shruthi, S. D. (2012). A review on Murraya koenigii: multipotential medicinal plant. Asian Journal of pharmaceutical and clinical research, 5(4), 5-14.
  • Hema, R., Kumaravel, S., & Alagusundaram, K. (2011). GC/MS determination of bioactive components of Murraya koenigii. Journal of American Science, 7(1), 80-83.
  • Indhumathi, K., Vidhya, D., Gurusamy, K., Paramaguru, P., & Santhi, V. P. (2020). Genetic Variability Studies and Character Association for Yield and Quality Traits in Curry leaf (Murraya koengii (L.) Spreng.). Chemical Engineering, 1, 164.
  • Igara, C. E., Omoboyowa, D. A., Ahuchaogu, A. A., Orji, N. U., & Ndukwe, M. K. (2016). Phytochemical and nutritional profile of Murraya koenigii (Linn) Spreng leaf. Journal of Pharmacognosy and Phytochemistry, 5(5), 07-09.
  • Iqbal, Z., Mehmood, H. K., Hussain, M., Mehmood, M. H. R., & Choudhry, M. N. (2017). Antioxidant activity of essential oil from the leaves and stems of Murraya koenigii. World Journal of Pharmaceutical Research, 6(7), 267-273.
  • Iyer, D., & Devi, U. (2008). Phyto-pharmacology of Murraya koenigii (L.). Pharmacognosy Reviews, 2(3), 180.
  • Jachak, S. M., Thakur, M. S., Ahirrao, P., & Goyal, A. (2024). Murraya koenigii (L.) Spreng. as a Natural Intervention for Diabesity: A Review. Current Pharmaceutical Design, 30(41), 3255-3275. https://doi.org/10.2174/0113816128304471240801183021
  • Jain, M., Gilhotra, R., Singh, R. P., & Mittal, J. (2017). Curry leaf (Murraya koenigii): A spice with medicinal property. MOJ Biol Med, 2(3), 236-256. https://doi.org/10.15406/mojbm.2017.02.00050
  • Joseph, S., & Peter, K. V. (1985). Curry leaf (Murraya koenigii), perennial, nutritious, leafy vegetable. Economic Botany, 39, 68-73. https://doi.org/10.1007/BF02861176
  • Khan, B. A., Abraham, A., & Leelamma, S. (1996). Role of Murraya koenigii (curry leaf) and Brassica juncea (Mustard) in lipid peroxidation. Indian Journal of Physiology and Pharmacology, 40, 155-158.
  • Khurana, A., Sikha, M. S., Ramesh, K., Venkatesh, P., & Godugu, C. (2019). Modulation of cerulein‐induced pancreatic inflammation by hydroalcoholic extract of curry leaf (Murraya koenigii). Phytotherapy Research, 33(5), 1510-1525. https://doi.org/10.1002/ptr.6344
  • Kundu, P., Sharma, P., Mahato, R., Saha, M., Das, S., & Ghosh, P. (2020). A brief review for the development of bio-nanoparticles using some important Indian ethnomedicinal plants. Journal of Medicinal Plant Studies, 8(6), 26-33. https://doi.org/10.22271/plants.2020.v8.i6a.1226
  • Kureel, S. P., Kapil, R. S., & Popli, S. P. (1970). Two novel alkaloids from Murraya koenigii Spreng: mahanimbicine and bicyclomahanimbicine. Chemistry & industry, 29, 958.
  • Kushwaha, A., Shrivastava, P., Sachan, P., Gupta, S., & Goswami, M. (2024). Understanding the COVID-19 Pandemic: An Overview of Ayurvedic and Traditional Formulations used for COVID-19. Journal of Research in Complementary Medicine, 1(1), 19-37. http://dx.doi.org/10.5455/JRCM.20240205070319
  • Lawal, H., Atiku, M. K., Khelpai, D. G., & Wannang, N. N. (2008). Hypoglycaemic and hypolipidaemic effects of the aqueous leaf extract of Murraya koenigii in normal and alloxan–diabetic rats. Nigerian Journal of Physiological Sciences, 23(1-2). https://doi.org/10.4314/njps.v23i1-2.54919
  • Malode, G. P., Parbat, A. Y., Shaikh, A. R., Panchale, W. A., Manwar, J. V., & Bakal, R. L. (2021). Phytochemistry, pharmacology and botanical aspects of Murraya Koenigii in the search for molecules with bioactive potential-A review. GSC Advanced Research and Reviews, 6(3), 143-155. https://doi.org/10.30574/gscarr.2021.6.3.0055
  • Manandhar, D. (2021). Review Article on Status of Soybean Production in Nepal. Reviews in Food and Agriculture (RFNA), 2(2), 31-33.
  • Mandal, S., Nayak, A., Kar, M., Banerjee, S. K., Das, A., Upadhyay, S. N., Singh, R. K., Banerji, A., & Banerji, J. (2010). Antidiarrhoeal activity of carbazole alkaloids from Murraya koenigii Spreng (Rutaceae) seeds. Fitoterapia, 81(1), 72–74. https://doi.org/10.1016/j.fitote.2009.08.016
  • Manna, P., Sinha, M., & Sil, P. C. (2008). Amelioration of cadmium-induced cardiac impairment by taurine. Chemico-biological interactions, 174(2), 88-97. https://doi.org/10.1016/j.cbi.2008.05.005
  • Mitra, E., Ghosh, A. K., Ghosh, D., Mukherjee, D., Chattopadhyay, A., Dutta, S., Pattari, S. K., & Bandyopadhyay, D. (2012). Protective effect of aqueous Curry leaf (Murraya koenigii) extract against cadmium-induced oxidative stress in rat heart. Food and chemical toxicology, 50(5), 1340–1353. https://doi.org/10.1016/j.fct.2012.01.048
  • Nagappan, T., Ramasamy, P., Wahid, M. E. A., Segaran, T. C., & Vairappan, C. S. (2011). Biological activity of carbazole alkaloids and essential oil of Murraya koenigii against antibiotic resistant microbes and cancer cell lines. Molecules, 16(11), 9651-9664. https://doi.org/10.3390/molecules16119651
  • Nigam, L. (2023). Curry Leaf (Murraya koenigii): A Wonder Spice with Medicinal Value. Journal of Advancement in Pharmacognosy, 4(1).
  • Ningappa, M. B., Dhananjaya, B. L., Dinesha, R., Harsha, R., & Srinivas, L. (2010). Potent antibacterial property of APC protein from curry leaves (Murraya koenigii L.). Food chemistry, 118(3), 747-750. https://doi.org/10.1016/j.foodchem.2009.05.059
  • Ningappa, M. B., Dinesha, R., & Srinivas, L. (2008). Antioxidant and free radical scavenging activities of polyphenol-enriched curry leaf (Murraya koenigii L.) extracts. Food chemistry, 106(2), 720-728. https://doi.org/10.1016/j.foodchem.2007.06.057
  • Ningappa, M. B., & Srinivas, L. (2008). Purification and characterization of∼ 35 kDa antioxidant protein from curry leaves (Murraya koenigii L.). Toxicology in vitro, 22(3), 699-709. https://doi.org/10.1016/j.tiv.2007.11.009
  • Prajapati, N. D., Purohit, S. S., Sharma, A. K., & Kumar, T. (2003). A handbook of medicinal plants: A complete source book (pp. 554-554).
  • Raghavan, R. S. (1957, June). Chromosome numbers in Indian medicinal plants. In Proceedings/Indian Academy of Sciences (Vol. 45, No. 6, pp. 294-298). New Delhi: Springer India. https://doi.org/10.1007/BF03051030
  • Raina, V. K., Lal, R. K., Tripathi, S., Khan, M., Syamasundar, K. V., & Srivastava, S. K. (2002). Essential oil composition of genetically diverse stocks of Murraya koenigii from India. Flavour and fragrance journal, 17(2), 144-146. https://doi.org/10.1002/ffj.1058
  • Rajendran, M. P., Pallaiyan, B. B., & Selvaraj, N. (2014). Chemical composition, antibacterial and antioxidant profile of essential oil from Murraya koenigii (L.) leaves. Avicenna journal of phytomedicine, 4(3), 200. PMCID: PMC4104627
  • Ramnath, G. M., Jayaraman, S., Thirugnanasampandan, R., Gunasekaran, B., & Gopalakrishnan, A. (2023). Chemical composition analysis and evaluation of antioxidant, antiacetylcholinesterase and cytotoxicity of Murraya koenigii (l.) Spreng fruit oil. Journal of microbiology, biotechnology and food sciences, 13(3), e6135-e6135.
  • Rana, V. S., Juyal, J. P., & Blazquez, M. A. (2004). Chemical constituents of the volatile oil of Murraya koenigii leaves. International Journal of Aromatherapy, 14(1), 23-25. https://doi.org/10.1016/j.ijat.2003.12.007
  • Rao, B. R., Rajput, D. K., & Mallavarapu, G. R. (2011). Chemical diversity in curry leaf (Murraya koenigii) essential oils. Food Chemistry, 126(3), 989-994. https://doi.org/10.1016/j.foodchem.2010.11.106
  • Rao, L. J. M., Ramalakshmi, K., Borse, B. B., & Raghavan, B. (2007). Antioxidant and radical-scavenging carbazole alkaloids from the oleoresin of curry leaf (Murraya koenigii Spreng.). Food Chemistry, 100(2), 742-747. https://doi.org/10.1016/j.foodchem.2005.10.033
  • Rastogi, R. M. (1990). Compendium of Indian medicinal plants. Central Drug Research Institute, Lucknow, India, 1, 388-389.
  • Sachan, P., Shrivastava, P., & Goswami, M. (2024). Revolutionizing the Potential of Probiotics an Evidence-Based Review. Journal of Ravishankar University, Part-B Science, 37(2). https://doi.org/10.52228/JRUB.2024-37-2-7
  • Sachan, P., Shrivastava, P., & Goswami, M. (2025). Unleashing Translational Opportunities of Loco-Regional Drug Delivery to Treat Malignancy. Asian Pacific Journal of Cancer Biology, 10(1), 213-228.
  • Saini, S. C., & Reddy, G. B. S. (2015). A review on curry leaves (Murraya koenigii): Versatile multi-potential medicinal plant. Am J Phytomed Clin Ther, 3(4), 363-368.
  • Samanta, S. K., Kandimalla, R., Gogoi, B., Dutta, K. N., Choudhury, P., Deb, P. K., Devi, R., Pal, B. C., & Talukdar, N. C. (2018). Phytochemical portfolio and anticancer activity of Murraya koenigii and its primary active component, mahanine. Pharmacological research, 129, 227–236. https://doi.org/10.1016/j.phrs.2017.11.024
  • Sarswat, S., & Yadav, D. S. (2023). A Marvel Versatile, Multipotential Plant Murraya Koenigii: A Review. Knowledgeable Research: A Multidisciplinary Peer-Reviewd Refereed Journal, 1(12), 26-34.
  • Sasidharan, I., & Menon, A. N. (2011). Effects of temperature and solvent on antioxidant properties of curry leaf (Murraya koenigii L.). Journal of food science and technology, 48, 366-370. https://doi.org/10.1007/s13197-010-0134-x
  • Sharma, M., Urvashi, Gupta, H., Anmol, Sharma, U., & Reddy, S. E. (2024). Chemical Composition and Insecticidal Potential of Essential Oil from Murraya koenigii (L.) Obtained by Natural Deep Eutectic Solvents. Neotropical Entomology, 1-14. https://doi.org/10.1007/s13744-024-01207-9
  • Sharma, R., & Kumar, U. (2019). Exploration and phytochemical estimation of Murraya koenigii leaves for pharmaceutical applications. Asian Journal of Pharmaceutical Research, 9(3), 159-168.
  • Singh, S., Ahuja, A., Murti, Y., & Khaliq, A. (2023). Phyto‐Pharmacological Review on Murraya koenigii (L.) Spreng: As an Indigenous Plant of India with High Medicinal Potential. Chemistry & Biodiversity, 20(7), e202300483. https://doi.org/10.1002/cbdv.202300483
  • Singh, S., More, P. K., & Mohan, S. M. (2014). Curry leaves (Murraya koenigii Linn. Sprengal)-a mircale plant. Indian Journal of Scientific Research, 4(1), 46-52.
  • Soundappan, K., Bajaj, R., Vaidya, B. N., & Joshee, N. (2018). Anatomical and biochemical investigations on medicinal tree Murraya koenigii Spreng. Journal of Biotech Research, 9, 70-78.
  • Syaifurrisal, A., Suciyono, S., Santanumurti, M. B., Prajitno, A., Fadjar, M., Riyadi, F. M., Fauziyyah, A. I., Pariawan, A., & Abualreesh, M. H. (2024). Effect of Curry Leaf (Murraya koenigii) as Edwardsiellosis Treatment on Gourami Fish (Osphronemus goramy). Aquatic Sciences and Engineering, 39(3), 179-188. https://doi.org/10.26650/ASE20231367517
  • Tripathi, Y. C., Anjum, N., & Rana, A. (2018). Chemical composition and in vitro antifungal and antioxidant activities of essential oil from Murraya koenigii (L.) Spreng. Leaves. Asian Journal of Biomedical and Pharmaceutical Sciences, 8(65), 6-13.
  • Uraku, A. J., & Nwankwo, V. O. (2015). Phytochemical and nutritional composition analysis of Murraya koenigii Linn leaves. British Journal of Pharmaceutical Research, 6(3), 174-180. https://doi.org/10.9734/BJPR/2015/15595
  • Verma, D., Macwan, D., Patel, J. D., Parmar, S. R., & Patel, H. V. (2022). Herbs that heal: Role of traditional herbal remedies as an immunity booster and effective against the infectious and systemic diseases. Annals of Phytomedicine, 11(2), 7-16. http://dx.doi.org/10.54085/ap.2022.11.2.2
  • Verma, R. S., Chauhan, A., Padalia, R. C., Jat, S. K., Thul, S., & Sundaresan, V. (2013). Phytochemical diversity of Murraya koenigii (L.) Spreng. from western Himalaya. Chemistry & Biodiversity, 10(4), 628-641. https://doi.org/10.1002/cbdv.201200054
  • Visakh, N. U., Pathrose, B., & Narayanankutty, A. (2023). Characterization of secondary metabolites from the leaves of curry leaf (Murraya koenigii L.) essential oils with insecticidal activities against stored product insects. Biocatalysis and Agricultural Biotechnology, 54, 102973. https://doi.org/10.1016/j.bcab.2023.102973
  • Viswanathan, K., Ashok, B., & Pugazhendhi, A. (2020). Comprehensive study of engine characteristics of novel biodiesel from curry leaf (Murraya koenigii) oil in ceramic layered diesel engine. Fuel, 280, 118586. https://doi.org/10.1016/j.fuel.2020.118586
  • Wee, A. S., Thew, H. Y., Liew, S. Y., Tan, W. N., & Khaw, K. Y. (2024). Anti-cholinesterase profile of Murraya koenigii (L.) Spreng essential oil and its chemical constituents. Journal of Essential Oil Bearing Plants, 1-11. https://doi.org/10.1080/0972060X.2024.2398676
  • Xie, J. T., Chang, W. T., Wang, C. Z., Mehendale, S. R., Li, J., Ambihaipahar, R., Ambihaipahar, U., Fong, H. H., & Yuan, C. S. (2006). Curry leaf (Murraya koenigii Spreng.) reduces blood cholesterol and glucose levels in ob/ob mice. The American journal of Chinese medicine, 34(2), 279–284. https://doi.org/10.1142/S0192415X06003825
  • Yankuzo, H., Ahmed, Q. U., Santosa, R. I., Akter, S. F. U., & Talib, N. A. (2011). Beneficial effect of the leaves of Murraya koenigii (Linn.) Spreng (Rutaceae) on diabetes-induced renal damage in vivo. Journal of Ethnopharmacology, 135(1), 88-94. https://doi.org/10.1016/j.jep.2011.02.020
  • You, C., Zhang, W., Guo, S., Wang, C., Yang, K., Liang, J., Wang, Y., Geng, Z., Du, S., & Deng, Z. (2015). Chemical composition of essential oils extracted from six Murraya species and their repellent activity against Tribolium castaneum. Industrial Crops and Products, 76, 681–687. https://doi.org/10.1016/j.indcrop.2015.07.044
  • Zou, Q., Huang, Y., Zhang, W., Lu, C., & Yuan, J. (2023). A comprehensive review of the pharmacology, chemistry, traditional uses and quality control of star anise (Illicium verum Hook. F.): An aromatic medicinal plant. Molecules, 28(21), 7378. https://doi.org/10.3390/molecules28217378
Toplam 86 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Geleneksel Çin Tıbbı ve Tedavileri
Bölüm Derleme Makaleleri
Yazarlar

Pranjal Sachan 0009-0004-8844-5940

Prachi Shrivastava 0000-0003-1241-4019

Akansha Kushwaha 0000-0002-5112-9344

Kris Jain 0009-0000-0173-8750

Laxmi Kant 0000-0002-6927-4582

Erken Görünüm Tarihi 30 Nisan 2025
Yayımlanma Tarihi 30 Nisan 2025
Gönderilme Tarihi 8 Kasım 2024
Kabul Tarihi 4 Mart 2025
Yayımlandığı Sayı Yıl 2025 Cilt: 6 Sayı: 1

Kaynak Göster

APA Sachan, P., Shrivastava, P., Kushwaha, A., Jain, K., vd. (2025). A deep dive into the phytochemical composition of Murraya koenigii (curry leaf): Active compounds and their therapeutic implications. Bütünleyici Ve Anadolu Tıbbı Dergisi, 6(1), 40-59. https://doi.org/10.53445/batd.1581503
 Kapak Resmi İndir
J Integrative Anatolian Med & Bütünleyici Anadolu Tıbbı Derg

◆◆◆


◆◆◆
by-nc.png