The potential of bee products in alternative medicine

Mehmet İlkaya; Abdurrahman Şimşek; Zeynep Asutay; Muhammed Dinç

Derleme

The potential of bee products in alternative medicine

Yıl 2024, Cilt: 4 Sayı: 1, 25 - 36, 07.07.2024

Mehmet İlkaya , Abdurrahman Şimşek , Zeynep Asutay Muhammed Dinç

Öz

Bee products have been used in natural treatment methods for thousands of years, and these products include honey, propolis, royal jelly, pollen and bee venom. During this period, the increasing population constitutes the potential increase and usage areas in alternative medicine. Honey is known for its antioxidant, antibacterial and anti-inflammatory properties. It is especially effective in wound application and penal treatment. The administration of honey can help strengthen the immune system with enzymes and vitamins. Propolis is a specialized substance that bees produce to protect their hives from microbes. Propolis, which has antibacterial, antifungal and antiviral effects, is used to support oral health, fight infections and protect against infections such as colds. Royal jelly is a substance that owns the high nutrient
part produced to feed the queen bee. It is rich in vitamins, minerals and amino acids. Royal jelly is used to increase energy documents, support skin health and support general health. The immune system can be strengthened and delay its law. Pollen is known for its high protein content that bees collect from plants. Thanks to its antioxidant properties, it can prevent damage areas and have positive effects on general health. In alternative medicine, pollen is used to provide energy, support health and enhance health. It is especially effective in treating inflammatory diseases such as arthritis. In a method called apitherapy, the effects of bee venom on the immune system and the strengthening of the moon are called. As a result, the opportunities in alternative medicine at the top are wide and varied. Honey, propolis, royal jelly, pollen and bee venom can be used for the prevention and treatment of various health problems. However, it is important to consult a health professional before using this product. For more information on popular medical uses, do more research and discover something new.

Anahtar Kelimeler

Bee Products, Alternative medicine, Supportive treatment

Etik Beyan

Yok

Destekleyen Kurum

Yok

Teşekkür

Yok

Kaynakça

[1] Abdel-Latif, M.M., 2015. Chemoprevention of gastrointestinal cancers by natural honey. World Journal Pharmacology 4[1]: 160-167. [46] Ayda, B., 2003. Deli bal zehirlenmesi. Yoğun Bakım Dergisi, 3[1]: 33-36.
[2] Ajibola, A., Chamunorwa, J.P., Erlwanger, K.H., 2012. Nutraceutical values of natural honey and its contribution to human health and wealth. Nutrition and Metabolism 9[61]: 1-13.
[3] Alzahrani, H.A., Alsabehi, R., Boukraâ, L., Abdellah, F., Bellik, Y., Bakhotmah, B.A., 2012. Antibacterial and antioxidant potency of floral honeys from different botanical and geographical origins. Molecules, 17[9]: 10540-10549.
[4] Anonim, 2010. TSE 3036 Bal Standardı. 19 Ocak 2010 Kabul Tarihli Bal Standardı, Ankara.
[5] Anonim, 2012. Türk Gıda Kodeksi Bal Tebliği [2012/58]. Gıda Tarım ve Hayvancılık Bakanlığı, 27 Temmuz 2012 Tarih ve 28366 Sayılı Resmi Gazete, Ankara.
[6] Ayna, A., Tunc, A., Özbolat, S. N., Bengü, A. Ş., Aykutoğlu, G., Canli, D., ... & Darendelioğlu, E. 2021. Anticancer, and antioxidant activities of royal jelly on HT-29 colon cancer cells andmelissopalynological analysis. Turkish Journal of Botany, 45[8], 809-819.
[7] Başoğlu, F.N., Sorkun, K., Löker, M., Doğan, C., Wetherilt, H., 1996. Saf ve sahte balların ayırt edilmesinde fiziksel, kimyasal ve palinolojik kriterlerin saptanması. Gıda Dergisi 21[2]: 67-73.
[8] Batu, A., Küçük, E., Çimen, M., 2013. Doğu Anadolu ve Doğu Karadeniz Bölgeleri çiçek ballarının fizikokimyasal ve biyokimyasal değerlerinin belirlenmesi. Electronic Journal of Food Technologies 8[1]: 52-62.
[9] Bayram, N. E., Canli, D., Gercek, Y. C., Bayram, S., Celik, S., GÜZEL, F., ... & Oz, G. C. 2020. Macronutrient and micronutrient levels and phenolic compound characteristics of monofloral honey samples. Journal of Food & Nutrition Research, 59[4].
[10] Begum, S.B., Roobia, R.R., Karthikeyan, M., Murugappan, R., 2015. Validation of nutraceutical properties of honey and probiotic potential of its innate microflora. LWT-Food Science and Technology 60[2]: 743-750.
[11] Belay, A., Solomon, W., Bultossa, G., Adgaba, N., Melaku, S., 2015. Botanical origin, colour, granulation and sensory properties of the Harenna forest honey, Bale, Ethiopia. Food Chemistry 167: 213-219.
[12] Bengü, A. Ş. 2022. Balın kimyası, özellikleri ve sağlığımız. Bingöl Üniversitesi Sağlık Dergisi, 2[2], 93-98.
[13] Bengü, A. Ş., Ayna, A., Özbolat, S., Tunç, A., Aykutoğlu, G., Çiftci, M., & Darendelioğlu, E. 2020. Content and antimicrobial activities of bingol royal jelly. Türk Tarım ve Doğa Bilimleri Dergisi, 7[2], 480-486.
[14] Bilgen-Çınar, S., 2010. Türk çam balının analitik özellikleri. Ankara Üniversitesi Fen Bilimleri Enstitüsü Gıda Mühendisliği Anabilim Dalı Doktora, Türkiye. 81 ss.
[15] Bogdanov, S., 2012. Bee venom: Composition, health, medicine: A review. Peptides 44: 18-22.
[16] Can, Z., Yildiz, O., Sahin, H., Turumtay, E.A., Silici, S., Kolayli, S., 2015. An investigation of Turkish honeys: Their physico-chemical properties, antioxidant capacities and phenolic profiles. Food Chemistry 180:133-141.
[17] Choudhari, M.K., Haghniaz, R., Rajwade, J.M., Paknikar K.M., 2013. Anticancer activity of Indian stingless bee propolis: an in vitro study. EvidenceBased Complementary and Alternative Medicine http://dx.doi.org/10.1155/2012/410406.
[18] Chua, L.S., Abdul-Rahaman, N.L., Sarmidi, M.R., Aziz, R., 2012. Multi-elemental composition and physical properties of honey samples from Malaysia. Food Chemistry 135[3]: 880-887.
[19] Chua, L.S., Rahaman, N.L.A., Adnan, N.A., Tijh, T., Tan, E., 2013. Antioxidant activity of three honey samples in relation with their biochemical components. Journal of Analytical Methods in Chemistry http://dx.doi.org/10.1155/2013/313798.
[20] Coşkun, P., & İnci H,. 2020. Propolisin kimyasal içeriği ile antibakteriyel, antiviral ve antioksidan aktivitesi. ISPEC Journal of Agricultural Sciences, 4[4], 1053-1070.
[21] Di Pasquale, G., Salignon, M., Le Conte, Y., Belzunces, L.P., Decourtye, A., Kretzschmar, A., Suchail, S., Brunet, J-L., Alaux, C., 2013. Influence of pollen nutrition on honey bee health: do pollen quality and diversity matter. PloS One 8[8]: e72016.
[22] Döner, Ö., & İnci H,. 2021. Bingöl ilinin farklı bölgelerinden elde edilen propolislerin protein oranı ve kül miktarı açısından karşılaştırılması. ISPEC Journal of Agricultural Sciences, 5[2], 372-380.
[23] Erejuwa, O.O., Sulaiman, S.A., Wahab, M.S.A., 2014. Effects of honey and its mechanisms of action on the development and progression of cancer. Molecules 19[2]: 2497-2522.
[23] Escuredo, O., Dobre, I., Fernández-González, M., Seijo, M.C., 2014. Contribution of botanical origin and sugar composition of honeys on the crystallization phenomenon. Food Chemistry 149:84-90.
[24] Escuredo, O., Silva, L.R., Valentão, P., Seijo, M.C., Andrade, P.B., 2012. Assessing Rubus honey value: Pollen and phenolic compounds content and antibacterial capacity. Food Chemistry 130[3]: 671- 678.
[25] Gomes, S., Dias, L.G., Moreira, L.L., Rodrigues, P., Estevinho, L., 2010. Physicochemical, microbiological and antimicrobial properties of commercial honeys from Portugal. Food and Chemical Toxicology 48[2]: 544-548.
[26] Inci, H., Izol, E., Yilmaz, M. A., Ilkaya, M., Bingöl, Z., & Gülçin, I. 2023. Comprehensive phytochemical content by LC/MS/MS and anticholinergic, antiglaucoma, antiepilepsy, and antioxidant activity of apilarnil [drone larvae]. Chemistry & Biodiversity, 20[10], e202300654.
[27] Isidorov, V., Bagan, R., Bakier, S., Swiecicka, I., 2015. Chemical composition and antimicrobial activity of Polish herbhoneys. Food Chemistry 171: 84-88.
[28] Isla, M.I., Craig, A., Ordoñez, R., Zampin, C., Sayago, J., Bedascarrasbure, E., Alvarez, A., Salomón, V., Maldonado, L., 2011. Physico chemical and bioactive properties of honeys from Northwestern Argentina. LWT-Food Science and Technology 44[9]: 1922-1930.
[29] Islam, A., Khalil, I., Islam, N., Moniruzzaman, M., Mottalib, A., Sulaiman, S.A., Gan, S.H., 2012. Physicochemical and antioxidant properties of Bangladeshi honeys stored for more than one year. BMC Complementary and Alternative Medicine 12[1]: 177.
[30] İnci, H., Karakaya, E., & Topluk, O. 2022. Bingöl ili arıcılık işletmelerinin yapısal özellikleri. Türk Tarım ve Doğa Bilimleri Dergisi, 9[4], 996-1013.
[31] Jo, M., Park, M.H., Kollipara, P.S., An, B.J., Song, H.S., Han, S.B., Kim, J.H., Song, M.J., Hong, J.T., 2012. Anti-cancer effect of bee venom toxin and melittin in ovarian cancer cells through induction of death receptors and inhibition of JAK2/STAT3 pathway. Toxicology and Applied Pharmacology 258[1]: 72-81.
[32] Juan-Borrás, M., Domenech, E., Hellebrandova, M., Escriche, I., 2014. Effect of country origin on physicochemical, sugar and volatile composition of acacia, sunflower and tilia honeys. Food Research International 60: 86-94.
[33] Kabbani, D., Sepulcre, F., Wedekind, J., 2011. Ultrasound-assisted liquefaction of rosemary honey: Influence on rheology and crystal content. Journal of Food Engineering 107[2]: 173-178.
[34] Kahraman, T., Buyukunal, S.K., Vural, A., Altunatmaz, S.S., 2010. Physico-chemical properties in honey from different regions of Turkey. Food Chemistr 123[1]: 41-44.
[35] Karabagias, I.K., Badeka, A.V., Kontakos, S., Karabournioti, S., Kontominas, M.G., 2014. Botanical discrimination of Greek unifloral honeys with physico-chemical and chemometric analyses. Food Chemistry 165: 181-190.
[36] Karadal, F., Yıldırım, Y., 2012. Balın kalite nitelikleri, beslenme ve sağlık açısından önemi. Erciyes Üniversitesi Veterinerlik Fakültesi Dergisi 9[3]: 197-209.
[37] Karataş, F., Şerbetçi, Z., 2008. Arı polenlerindeki adrenalin ve noradrenalin miktarlarının HPLC ile belirlenmesi. Fırat Üniversitesi Fen ve Mühendislik Bilimleri Dergisi 20[3]: 419-422.
[38] Khalil, M.I., Moniruzzaman, M., Boukraâ, L., Benhanifia, M., Islam, M.A., Islam, M.N,, Sulaiman, S.A., Gan, S.H., 2012. Physicochemical and antioxidant properties of Algerian honey. Molecules 17[9]: 11199-11215.
[39] Köksel, H., 2007. Karbonhidratlar. Gıda Kimyası, Editör İ. Saldamlı, Hacettepe Üniversitesi Yayınları 3. Baskı, Ankara, 72-77s.
[40] Kurtoglu, A.B., Yavuz, R., Evrendilek, G.A., 2014. Characterisation and fate of grayanatoxins in mad C. Mutlu, M. Erbaş, S. Arslan Tortul Akademik Gıda 15[1] [2017] 75-83 83 honey produced from Rhododendron ponticum nectar. Food Chemistry 161: 47-52.
[41] Linkon, M., Prodhan, U.K., Elahi, T., Talukdar, J., Alim, M.A., Hakim, M.A., 2015. Comparative analysis of the physico-chemical and antioxidant properties of honey available in Tangail, Bangladesh. Universal Journal of Food and Nutrition Science 3[1]: 19-22.
[42] Manyi-Loh, C.E., Clarke, A.M., Ndip, R.N., 2011. An overview of honey: therapeutic properties and contribution in nutrition and human health. African Journal of Microbiology Research 5[8]: 844-852.
[43] Marshall, S., Gu, L., Schneider, K.R., 2015. Health benefits and medicinal value of honey. Ifas Extension, University of Florida.
[44] Moniruzzaman, M., Rodríguez, I., Ramil, M., Cela, R., Sulaiman, S., Gan, S., 2014. Assessment of gas chromatography time-of-flight accurate mass spectrometry for identification of volatile and semivolatile compounds in honey. Talant, 129: 505-515.
[45] Nisbet, C., Güler, A., Yarım G.F., Cenesiz, S., Ardalı, Y., 2013. Çevre ve flora kaynaklarının arı ürünlerinin mineral madde içerikleri ile ilişkisi. Turkish Journal of Biochemistry/Türk Biyokimya Dergisi, 38[4]: 494-498.
[46] Nombré, I., Schweitzer, P., Boussim, J.I., Rasolodimby, J.M., 2010. Impacts of storage conditions on physicochemical characteristics of honey samples from Burkina Faso. African Journal of Food Science 4[7]: 458-463.
[47] Oroian, M., 2013. Measurement, prediction and correlation of density, viscosity, surface tension and ultrasonic velocity of different honey types at different temperatures. Journal of Food Engineering 119[1]: 167-172.
[48] Oršolić, N., 2012. Bee venom in cancer therapy. Cancer and Metastasis Reviews 31[1-2]: 173-194.
[49] Othman, N.H., 2012. Honey and cancer: sustainable inverse relationship particularly for developing nations-a review. Evidence-Based Complementary and Alternative Medicine http://dx.doi.org/10.1155/2012/410406.
[50] Özcan, M.M., Ölmez, Ç., 2014. Some qualitative properties of different monofloral honeys. Food Chemistry 163: 212-218.
[51] Özmen, N., Alkın, E., 2006. Balın antimikrobiyel özellikleri ve insan sağlığı üzerine etkileri. Uludağ Arıcılık Dergisi 2006[4]: 155-[11] Spilioti, E., Jaakkola, M., Tolonen, T.,
[52] Lipponen, M., Virtanen, V., Chinou, I., Kassi, E., Karabournioti, S., Moutsatsou, P., 2014. Phenolic acid composition, antiatherogenic and anticancer potential of honeys derived from various regions in Greece. PloS One 9[4]: e94860.
[53] Park, M.H., Choi, M.S., Kwak, D.H., Oh, K.W., Yoon, D.Y., Han, S.B., Song, H.S., Song, M.J., Hong, J.T., 2011. Anti-cancer effect of bee venom in prostate cancer cells through activation of caspase pathway via inactivation of NF- κB. The Prostate 71[8]: 801-812.
[54] Ramadan, M.F., Al-Ghamdi, A., 2012. Bioactive compounds and health-promoting properties of royal jelly: A review. Journal of Functional Foods 4[1]: 39-52.
[55] Sak-Bosnar, M., Sakač, N., 2012. Direct potentiometric determination of diastase activity in honey. Food Chemistry 135[2]: 827-831. C. Mutlu, M. Erbaş, S. Arslan Tortul Akademik Gıda 15[1] [2017] 75-83 82
[56] Schmidt, J.O., 1997. Chemical composition and application: Bee Products: Properties, Applications, and Apitherapy, Edited by Mizrahi, A., Lensky, Y., Springer Science & Business Media 15-27 p.
[57] Shafiq, H., Iftikhar, F., Ahmad, A., Kaleem, M., Sair, A.T., 2012. Effect of crystallization on the water activity of honey. International Journal Of Food And Nutritional Sciences 3[3]: 1-6.
[58] Stephens, J., Greenwood, D., Fearnley, L., Bong, J., Schlothauer, R., Loomes, K., 2015. Honey production and compositional parameters. Processing and Impact on Active Components in Food 675-680.
[59] Sunay, A.E., Samancı, T., 2008. Arı ürünleri üretimi. BAL-DER Arı Ürünleri ile Sağlıklı Yaşam Platformu Derneği.
[60] Teles, F., da Silva, T.M., da Cruz-Júnior, F.P., Honorato, V.H., de Oliveira-Costa, H., Barbosa, A.P.F., de Oliveira, S.G., Porfírio, Z., Libório, A.B., Borges, R.L., 2015. Brazilian red propolis attenuates hypertension and renal damage in 5/6 renal ablation model. PloS One 10[1], 10.1371/journal.pone.0116535.
[61] Tornuk, F., Karaman, S., Ozturk, I., Toker, O.S., Tastemur, B., Sagdic, O., Dogan, M., Kayacier, A., 2013. Quality characterization of artisanal and retail Turkish blossom honeys: Determination of physicochemical, microbiological, bioactive properties and aroma profile. Industrial Crops and Products 46:124-131.
[62] Tunca, R.İ., Taşkın, A., Karadavut, U., 2015. Determination of bee products consumption habits and awareness level in some provinces in Turkey. Turkish Journal of Agriculture-Food Science and Technology 3[7]: 556-561.
[63] Yanniotis, S,, Skaltsi, S., Karaburnioti, S., 2006. Effect of moisture content on the viscosity of honey at different temperatures. Journal of Food Engineering 72[4]: 372-377.
[64] Zanini, S., Marzotto, M., Giovinazzo, F., Bassi, C., Bellavite, P., 2014. Effects of dietary components on cancer of the digestive system. Critical Reviews in Food Science and Nutrition 55[13]: 1870-1885.
[65] Zong, Q.S., Wu, J.Y., 2014. A new approach to the synthesis of royal jelly acid. Chemistry of Natural Compounds 50[3]: 399-401.

The potential of bee products in alternative medicine

Yıl 2024, Cilt: 4 Sayı: 1, 25 - 36, 07.07.2024

Mehmet İlkaya , Abdurrahman Şimşek , Zeynep Asutay Muhammed Dinç

Öz

Anahtar Kelimeler

Bee Products, Alternative medicine, Supportive treatment

Etik Beyan

Yok

Destekleyen Kurum

Yok

Teşekkür

Yok

Kaynakça

[1] Abdel-Latif, M.M., 2015. Chemoprevention of gastrointestinal cancers by natural honey. World Journal Pharmacology 4[1]: 160-167. [46] Ayda, B., 2003. Deli bal zehirlenmesi. Yoğun Bakım Dergisi, 3[1]: 33-36.
[2] Ajibola, A., Chamunorwa, J.P., Erlwanger, K.H., 2012. Nutraceutical values of natural honey and its contribution to human health and wealth. Nutrition and Metabolism 9[61]: 1-13.
[3] Alzahrani, H.A., Alsabehi, R., Boukraâ, L., Abdellah, F., Bellik, Y., Bakhotmah, B.A., 2012. Antibacterial and antioxidant potency of floral honeys from different botanical and geographical origins. Molecules, 17[9]: 10540-10549.
[4] Anonim, 2010. TSE 3036 Bal Standardı. 19 Ocak 2010 Kabul Tarihli Bal Standardı, Ankara.
[5] Anonim, 2012. Türk Gıda Kodeksi Bal Tebliği [2012/58]. Gıda Tarım ve Hayvancılık Bakanlığı, 27 Temmuz 2012 Tarih ve 28366 Sayılı Resmi Gazete, Ankara.
[6] Ayna, A., Tunc, A., Özbolat, S. N., Bengü, A. Ş., Aykutoğlu, G., Canli, D., ... & Darendelioğlu, E. 2021. Anticancer, and antioxidant activities of royal jelly on HT-29 colon cancer cells andmelissopalynological analysis. Turkish Journal of Botany, 45[8], 809-819.
[7] Başoğlu, F.N., Sorkun, K., Löker, M., Doğan, C., Wetherilt, H., 1996. Saf ve sahte balların ayırt edilmesinde fiziksel, kimyasal ve palinolojik kriterlerin saptanması. Gıda Dergisi 21[2]: 67-73.
[8] Batu, A., Küçük, E., Çimen, M., 2013. Doğu Anadolu ve Doğu Karadeniz Bölgeleri çiçek ballarının fizikokimyasal ve biyokimyasal değerlerinin belirlenmesi. Electronic Journal of Food Technologies 8[1]: 52-62.
[9] Bayram, N. E., Canli, D., Gercek, Y. C., Bayram, S., Celik, S., GÜZEL, F., ... & Oz, G. C. 2020. Macronutrient and micronutrient levels and phenolic compound characteristics of monofloral honey samples. Journal of Food & Nutrition Research, 59[4].
[10] Begum, S.B., Roobia, R.R., Karthikeyan, M., Murugappan, R., 2015. Validation of nutraceutical properties of honey and probiotic potential of its innate microflora. LWT-Food Science and Technology 60[2]: 743-750.
[11] Belay, A., Solomon, W., Bultossa, G., Adgaba, N., Melaku, S., 2015. Botanical origin, colour, granulation and sensory properties of the Harenna forest honey, Bale, Ethiopia. Food Chemistry 167: 213-219.
[12] Bengü, A. Ş. 2022. Balın kimyası, özellikleri ve sağlığımız. Bingöl Üniversitesi Sağlık Dergisi, 2[2], 93-98.
[13] Bengü, A. Ş., Ayna, A., Özbolat, S., Tunç, A., Aykutoğlu, G., Çiftci, M., & Darendelioğlu, E. 2020. Content and antimicrobial activities of bingol royal jelly. Türk Tarım ve Doğa Bilimleri Dergisi, 7[2], 480-486.
[14] Bilgen-Çınar, S., 2010. Türk çam balının analitik özellikleri. Ankara Üniversitesi Fen Bilimleri Enstitüsü Gıda Mühendisliği Anabilim Dalı Doktora, Türkiye. 81 ss.
[15] Bogdanov, S., 2012. Bee venom: Composition, health, medicine: A review. Peptides 44: 18-22.
[16] Can, Z., Yildiz, O., Sahin, H., Turumtay, E.A., Silici, S., Kolayli, S., 2015. An investigation of Turkish honeys: Their physico-chemical properties, antioxidant capacities and phenolic profiles. Food Chemistry 180:133-141.
[17] Choudhari, M.K., Haghniaz, R., Rajwade, J.M., Paknikar K.M., 2013. Anticancer activity of Indian stingless bee propolis: an in vitro study. EvidenceBased Complementary and Alternative Medicine http://dx.doi.org/10.1155/2012/410406.
[18] Chua, L.S., Abdul-Rahaman, N.L., Sarmidi, M.R., Aziz, R., 2012. Multi-elemental composition and physical properties of honey samples from Malaysia. Food Chemistry 135[3]: 880-887.
[19] Chua, L.S., Rahaman, N.L.A., Adnan, N.A., Tijh, T., Tan, E., 2013. Antioxidant activity of three honey samples in relation with their biochemical components. Journal of Analytical Methods in Chemistry http://dx.doi.org/10.1155/2013/313798.
[20] Coşkun, P., & İnci H,. 2020. Propolisin kimyasal içeriği ile antibakteriyel, antiviral ve antioksidan aktivitesi. ISPEC Journal of Agricultural Sciences, 4[4], 1053-1070.
[21] Di Pasquale, G., Salignon, M., Le Conte, Y., Belzunces, L.P., Decourtye, A., Kretzschmar, A., Suchail, S., Brunet, J-L., Alaux, C., 2013. Influence of pollen nutrition on honey bee health: do pollen quality and diversity matter. PloS One 8[8]: e72016.
[22] Döner, Ö., & İnci H,. 2021. Bingöl ilinin farklı bölgelerinden elde edilen propolislerin protein oranı ve kül miktarı açısından karşılaştırılması. ISPEC Journal of Agricultural Sciences, 5[2], 372-380.
[23] Erejuwa, O.O., Sulaiman, S.A., Wahab, M.S.A., 2014. Effects of honey and its mechanisms of action on the development and progression of cancer. Molecules 19[2]: 2497-2522.
[23] Escuredo, O., Dobre, I., Fernández-González, M., Seijo, M.C., 2014. Contribution of botanical origin and sugar composition of honeys on the crystallization phenomenon. Food Chemistry 149:84-90.
[24] Escuredo, O., Silva, L.R., Valentão, P., Seijo, M.C., Andrade, P.B., 2012. Assessing Rubus honey value: Pollen and phenolic compounds content and antibacterial capacity. Food Chemistry 130[3]: 671- 678.
[25] Gomes, S., Dias, L.G., Moreira, L.L., Rodrigues, P., Estevinho, L., 2010. Physicochemical, microbiological and antimicrobial properties of commercial honeys from Portugal. Food and Chemical Toxicology 48[2]: 544-548.
[26] Inci, H., Izol, E., Yilmaz, M. A., Ilkaya, M., Bingöl, Z., & Gülçin, I. 2023. Comprehensive phytochemical content by LC/MS/MS and anticholinergic, antiglaucoma, antiepilepsy, and antioxidant activity of apilarnil [drone larvae]. Chemistry & Biodiversity, 20[10], e202300654.
[27] Isidorov, V., Bagan, R., Bakier, S., Swiecicka, I., 2015. Chemical composition and antimicrobial activity of Polish herbhoneys. Food Chemistry 171: 84-88.
[28] Isla, M.I., Craig, A., Ordoñez, R., Zampin, C., Sayago, J., Bedascarrasbure, E., Alvarez, A., Salomón, V., Maldonado, L., 2011. Physico chemical and bioactive properties of honeys from Northwestern Argentina. LWT-Food Science and Technology 44[9]: 1922-1930.
[29] Islam, A., Khalil, I., Islam, N., Moniruzzaman, M., Mottalib, A., Sulaiman, S.A., Gan, S.H., 2012. Physicochemical and antioxidant properties of Bangladeshi honeys stored for more than one year. BMC Complementary and Alternative Medicine 12[1]: 177.
[30] İnci, H., Karakaya, E., & Topluk, O. 2022. Bingöl ili arıcılık işletmelerinin yapısal özellikleri. Türk Tarım ve Doğa Bilimleri Dergisi, 9[4], 996-1013.
[31] Jo, M., Park, M.H., Kollipara, P.S., An, B.J., Song, H.S., Han, S.B., Kim, J.H., Song, M.J., Hong, J.T., 2012. Anti-cancer effect of bee venom toxin and melittin in ovarian cancer cells through induction of death receptors and inhibition of JAK2/STAT3 pathway. Toxicology and Applied Pharmacology 258[1]: 72-81.
[32] Juan-Borrás, M., Domenech, E., Hellebrandova, M., Escriche, I., 2014. Effect of country origin on physicochemical, sugar and volatile composition of acacia, sunflower and tilia honeys. Food Research International 60: 86-94.
[33] Kabbani, D., Sepulcre, F., Wedekind, J., 2011. Ultrasound-assisted liquefaction of rosemary honey: Influence on rheology and crystal content. Journal of Food Engineering 107[2]: 173-178.
[34] Kahraman, T., Buyukunal, S.K., Vural, A., Altunatmaz, S.S., 2010. Physico-chemical properties in honey from different regions of Turkey. Food Chemistr 123[1]: 41-44.
[35] Karabagias, I.K., Badeka, A.V., Kontakos, S., Karabournioti, S., Kontominas, M.G., 2014. Botanical discrimination of Greek unifloral honeys with physico-chemical and chemometric analyses. Food Chemistry 165: 181-190.
[36] Karadal, F., Yıldırım, Y., 2012. Balın kalite nitelikleri, beslenme ve sağlık açısından önemi. Erciyes Üniversitesi Veterinerlik Fakültesi Dergisi 9[3]: 197-209.
[37] Karataş, F., Şerbetçi, Z., 2008. Arı polenlerindeki adrenalin ve noradrenalin miktarlarının HPLC ile belirlenmesi. Fırat Üniversitesi Fen ve Mühendislik Bilimleri Dergisi 20[3]: 419-422.
[38] Khalil, M.I., Moniruzzaman, M., Boukraâ, L., Benhanifia, M., Islam, M.A., Islam, M.N,, Sulaiman, S.A., Gan, S.H., 2012. Physicochemical and antioxidant properties of Algerian honey. Molecules 17[9]: 11199-11215.
[39] Köksel, H., 2007. Karbonhidratlar. Gıda Kimyası, Editör İ. Saldamlı, Hacettepe Üniversitesi Yayınları 3. Baskı, Ankara, 72-77s.
[40] Kurtoglu, A.B., Yavuz, R., Evrendilek, G.A., 2014. Characterisation and fate of grayanatoxins in mad C. Mutlu, M. Erbaş, S. Arslan Tortul Akademik Gıda 15[1] [2017] 75-83 83 honey produced from Rhododendron ponticum nectar. Food Chemistry 161: 47-52.
[41] Linkon, M., Prodhan, U.K., Elahi, T., Talukdar, J., Alim, M.A., Hakim, M.A., 2015. Comparative analysis of the physico-chemical and antioxidant properties of honey available in Tangail, Bangladesh. Universal Journal of Food and Nutrition Science 3[1]: 19-22.
[42] Manyi-Loh, C.E., Clarke, A.M., Ndip, R.N., 2011. An overview of honey: therapeutic properties and contribution in nutrition and human health. African Journal of Microbiology Research 5[8]: 844-852.
[43] Marshall, S., Gu, L., Schneider, K.R., 2015. Health benefits and medicinal value of honey. Ifas Extension, University of Florida.
[44] Moniruzzaman, M., Rodríguez, I., Ramil, M., Cela, R., Sulaiman, S., Gan, S., 2014. Assessment of gas chromatography time-of-flight accurate mass spectrometry for identification of volatile and semivolatile compounds in honey. Talant, 129: 505-515.
[45] Nisbet, C., Güler, A., Yarım G.F., Cenesiz, S., Ardalı, Y., 2013. Çevre ve flora kaynaklarının arı ürünlerinin mineral madde içerikleri ile ilişkisi. Turkish Journal of Biochemistry/Türk Biyokimya Dergisi, 38[4]: 494-498.
[46] Nombré, I., Schweitzer, P., Boussim, J.I., Rasolodimby, J.M., 2010. Impacts of storage conditions on physicochemical characteristics of honey samples from Burkina Faso. African Journal of Food Science 4[7]: 458-463.
[47] Oroian, M., 2013. Measurement, prediction and correlation of density, viscosity, surface tension and ultrasonic velocity of different honey types at different temperatures. Journal of Food Engineering 119[1]: 167-172.
[48] Oršolić, N., 2012. Bee venom in cancer therapy. Cancer and Metastasis Reviews 31[1-2]: 173-194.
[49] Othman, N.H., 2012. Honey and cancer: sustainable inverse relationship particularly for developing nations-a review. Evidence-Based Complementary and Alternative Medicine http://dx.doi.org/10.1155/2012/410406.
[50] Özcan, M.M., Ölmez, Ç., 2014. Some qualitative properties of different monofloral honeys. Food Chemistry 163: 212-218.
[51] Özmen, N., Alkın, E., 2006. Balın antimikrobiyel özellikleri ve insan sağlığı üzerine etkileri. Uludağ Arıcılık Dergisi 2006[4]: 155-[11] Spilioti, E., Jaakkola, M., Tolonen, T.,
[52] Lipponen, M., Virtanen, V., Chinou, I., Kassi, E., Karabournioti, S., Moutsatsou, P., 2014. Phenolic acid composition, antiatherogenic and anticancer potential of honeys derived from various regions in Greece. PloS One 9[4]: e94860.
[53] Park, M.H., Choi, M.S., Kwak, D.H., Oh, K.W., Yoon, D.Y., Han, S.B., Song, H.S., Song, M.J., Hong, J.T., 2011. Anti-cancer effect of bee venom in prostate cancer cells through activation of caspase pathway via inactivation of NF- κB. The Prostate 71[8]: 801-812.
[54] Ramadan, M.F., Al-Ghamdi, A., 2012. Bioactive compounds and health-promoting properties of royal jelly: A review. Journal of Functional Foods 4[1]: 39-52.
[55] Sak-Bosnar, M., Sakač, N., 2012. Direct potentiometric determination of diastase activity in honey. Food Chemistry 135[2]: 827-831. C. Mutlu, M. Erbaş, S. Arslan Tortul Akademik Gıda 15[1] [2017] 75-83 82
[56] Schmidt, J.O., 1997. Chemical composition and application: Bee Products: Properties, Applications, and Apitherapy, Edited by Mizrahi, A., Lensky, Y., Springer Science & Business Media 15-27 p.
[57] Shafiq, H., Iftikhar, F., Ahmad, A., Kaleem, M., Sair, A.T., 2012. Effect of crystallization on the water activity of honey. International Journal Of Food And Nutritional Sciences 3[3]: 1-6.
[58] Stephens, J., Greenwood, D., Fearnley, L., Bong, J., Schlothauer, R., Loomes, K., 2015. Honey production and compositional parameters. Processing and Impact on Active Components in Food 675-680.
[59] Sunay, A.E., Samancı, T., 2008. Arı ürünleri üretimi. BAL-DER Arı Ürünleri ile Sağlıklı Yaşam Platformu Derneği.
[60] Teles, F., da Silva, T.M., da Cruz-Júnior, F.P., Honorato, V.H., de Oliveira-Costa, H., Barbosa, A.P.F., de Oliveira, S.G., Porfírio, Z., Libório, A.B., Borges, R.L., 2015. Brazilian red propolis attenuates hypertension and renal damage in 5/6 renal ablation model. PloS One 10[1], 10.1371/journal.pone.0116535.
[61] Tornuk, F., Karaman, S., Ozturk, I., Toker, O.S., Tastemur, B., Sagdic, O., Dogan, M., Kayacier, A., 2013. Quality characterization of artisanal and retail Turkish blossom honeys: Determination of physicochemical, microbiological, bioactive properties and aroma profile. Industrial Crops and Products 46:124-131.
[62] Tunca, R.İ., Taşkın, A., Karadavut, U., 2015. Determination of bee products consumption habits and awareness level in some provinces in Turkey. Turkish Journal of Agriculture-Food Science and Technology 3[7]: 556-561.
[63] Yanniotis, S,, Skaltsi, S., Karaburnioti, S., 2006. Effect of moisture content on the viscosity of honey at different temperatures. Journal of Food Engineering 72[4]: 372-377.
[64] Zanini, S., Marzotto, M., Giovinazzo, F., Bassi, C., Bellavite, P., 2014. Effects of dietary components on cancer of the digestive system. Critical Reviews in Food Science and Nutrition 55[13]: 1870-1885.
[65] Zong, Q.S., Wu, J.Y., 2014. A new approach to the synthesis of royal jelly acid. Chemistry of Natural Compounds 50[3]: 399-401.

Toplam 66 adet kaynakça vardır.

Ayrıntılar

Birincil Dil	İngilizce
Konular	Polen Bilimi
Bölüm	Arı Ürünlerinin Alternatif Tıptaki Potansiyeli
Yazarlar	Mehmet İlkaya 0000-0002-1797-144X Abdurrahman Şimşek 0000-0001-5844-8471 Zeynep Asutay 0000-0002-5854-1040 Muhammed Dinç
Yayımlanma Tarihi	7 Temmuz 2024
Gönderilme Tarihi	5 Haziran 2024
Kabul Tarihi	2 Temmuz 2024
Yayımlandığı Sayı	Yıl 2024 Cilt: 4 Sayı: 1

Kaynak Göster

APA	İlkaya, M., Şimşek, A., Asutay, Z., Dinç, M. (2024). The potential of bee products in alternative medicine. BinBee – Arı Ve Doğal Ürünler Dergisi, 4(1), 25-36.

Kapak Resmi İndir

Makale Dosyaları

Tam Metin