Öz
Duloksetin, fibromiyalji tedavisi için onaylanmış bir serotonin-norepinefrin geri alım inhibitörüdür. Duloksetinin bulantı, uyuklama, uykusuzluk, iştah azalması, ağız kuruluğu ve kabızlık gibi birçok yan etkisi vardır. Uyku bruksizmi de duloksetinin çok nadir görülen bir yan etkisidir. Bu olgu sunumunda, duloksetin kullanımından sonra 4. haftada uyku bruksizmi gelişen ve 6. haftada şiddetli bruksizm sonrası daha önce kanal tedavisi görmüş olan 1. üst molar dişinde kırık gelişen 35 yaşında bir erkek hasta sunulmuştur. Kullanmakta olduğu duloksetin tedavisi kesildi ve tedaviye amitriptilin ile devam edildi. Amitriptilin tedavisinden sonra hastanın hem bruksizm hem de fibromiyalji semptomlarında belirgin bir azalma görüldü. Bir yıllık takip sonrasında bruksizm semptomları görülmedi.
Anahtar Kelimeler
Kaynakça
- Minakuchi H, Fujisawa M, Abe Y, Iida T, Oki K, Okura K, et al. Managements of sleep bruxism in adult: A systematic review. Jpn Dent Sci Rev. 2022;58:124-36.
- de la Hoz-Aizpurua JL, Díaz-Alonso E, LaTouche-Arbizu R, Mesa-Jiménez J. Sleep bruxism. Conceptual review and update. Med Oral Patol Oral Cir Bucal. 2011;16(2):e231-8.
- Lavigne GJ, Khoury S, Abe S, Yamaguchi T, Raphael K. Bruxism physiology and pathology: an overview for clinicians. J Oral Rehabil. 2008;35(7):476-94.
- Milanlioglu A. Paroxetine-induced severe sleep bruxism successfully treated with buspirone. Clinics (Sao Paulo). 2012;67(2):191-2.
- Rynn M, Russell J, Erickson J, Detke MJ, Ball S, Dinkel J, et al. Efficacy and safety of duloxetine in the treatment of generalized anxiety disorder: a flexible-dose, progressive-titration, placebo-controlled trial. Depress Anxiety. 2008;25(3):182-9.
- Şahin Onat S, Malas FÜ. Duloxetine-induced Sleep bruxism in fibromyalgia successfully treated with amitriptyline. Acta Reumatol Port. 2015;40(4):391-2.
- Albayrak Y, Ekinci O. Duloxetine-induced nocturnal bruxism resolved by buspirone: case report. Clin Neuropharmacol. 2011;34(4):137-8.
- Bulanda S, Ilczuk-Rypuła D, Nitecka-Buchta A, Nowak Z, Baron S, Postek-Stefańska L. Sleep bruxism in children: etiology, diagnosis, and treatment-A literature review. Int J Environ Res Public Health. 2021;18(18):9544.
- Goldstein G, DeSantis L, Goodacre C. Bruxism: Best evidence consensus statement. J Prosthodont. 2021;30(S1):91-101.
- de Baat C, Verhoeff MC, Ahlberg J, Manfredini D, Winocur E, Zweers P, et al. Medications and addictive substances potentially inducing or attenuating sleep bruxism and/or awake bruxism. J Oral Rehabil. 2021;48(3):343-54.
- Adams M. Antidepressant effects on REM sleep. Biology and Microbiology Graduate Students Plan B Research Projects. 2020;27:1-22.
Öz
Duloxetine is a serotonin-norepinephrine reuptake inhibitor that is approved for the treatment of fibromyalgia. Duloxetine has many side effects such as nausea, somnolence, insomnia, decreased appetite, dry mouth, and constipation. Sleep bruxism is also a very rare side effect of duloxetine. In this case report, a case of a 35-year-old male patient who developed sleep bruxism in the 4th week after duloxetine use, and fracture of the 1st upper molar tooth which had previously undergone root canal treatment after severe bruxism in the 6th week was presented. Duloxetine treatment was stopped and treatment was continued with amitriptyline. The patient had a significant reduction in both bruxism and fibromyalgia symptoms after the amitriptyline treatment. Bruxism symptoms were not observed after one year of follow-up.
Anahtar Kelimeler
Kaynakça
- Minakuchi H, Fujisawa M, Abe Y, Iida T, Oki K, Okura K, et al. Managements of sleep bruxism in adult: A systematic review. Jpn Dent Sci Rev. 2022;58:124-36.
- de la Hoz-Aizpurua JL, Díaz-Alonso E, LaTouche-Arbizu R, Mesa-Jiménez J. Sleep bruxism. Conceptual review and update. Med Oral Patol Oral Cir Bucal. 2011;16(2):e231-8.
- Lavigne GJ, Khoury S, Abe S, Yamaguchi T, Raphael K. Bruxism physiology and pathology: an overview for clinicians. J Oral Rehabil. 2008;35(7):476-94.
- Milanlioglu A. Paroxetine-induced severe sleep bruxism successfully treated with buspirone. Clinics (Sao Paulo). 2012;67(2):191-2.
- Rynn M, Russell J, Erickson J, Detke MJ, Ball S, Dinkel J, et al. Efficacy and safety of duloxetine in the treatment of generalized anxiety disorder: a flexible-dose, progressive-titration, placebo-controlled trial. Depress Anxiety. 2008;25(3):182-9.
- Şahin Onat S, Malas FÜ. Duloxetine-induced Sleep bruxism in fibromyalgia successfully treated with amitriptyline. Acta Reumatol Port. 2015;40(4):391-2.
- Albayrak Y, Ekinci O. Duloxetine-induced nocturnal bruxism resolved by buspirone: case report. Clin Neuropharmacol. 2011;34(4):137-8.
- Bulanda S, Ilczuk-Rypuła D, Nitecka-Buchta A, Nowak Z, Baron S, Postek-Stefańska L. Sleep bruxism in children: etiology, diagnosis, and treatment-A literature review. Int J Environ Res Public Health. 2021;18(18):9544.
- Goldstein G, DeSantis L, Goodacre C. Bruxism: Best evidence consensus statement. J Prosthodont. 2021;30(S1):91-101.
- de Baat C, Verhoeff MC, Ahlberg J, Manfredini D, Winocur E, Zweers P, et al. Medications and addictive substances potentially inducing or attenuating sleep bruxism and/or awake bruxism. J Oral Rehabil. 2021;48(3):343-54.
- Adams M. Antidepressant effects on REM sleep. Biology and Microbiology Graduate Students Plan B Research Projects. 2020;27:1-22.
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Konular | Romatoloji ve Artrit, Klinik Tıp Bilimleri (Diğer) |
| Bölüm | Olgu Sunumu |
| Yazarlar | |
| Erken Görünüm Tarihi | 8 Kasım 2024 |
| Yayımlanma Tarihi | 30 Aralık 2024 |
| Gönderilme Tarihi | 12 Mart 2024 |
| Kabul Tarihi | 1 Eylül 2024 |
| Yayımlandığı Sayı | Yıl 2024 Cilt: 26 Sayı: 3 |
Kaynak Göster
Duzce Medical Journal is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.