Öz
Plant latex is a natural product produced by a number of plant species which are used by different tribal communities in India as a folk medicinal treatment on natural wounds or cuts. Plant latex has a huge demand as herbal products in an aspect of clinical, therapeutical and also in agricultural sectors. Natural latex is composed of different important biomolecules like, tannins, flavonoids, glycosides, sterols, saponins etc. These different active chemical constituents have versatile medicinal activities against different pathogens such as bacteria, fungi, viruses and protozoans etc. Therefore, development of novel biological techniques is significant for the biosynthesis of ZnO nanoparticles using the latex of Carica papaya L. This study reports on the biosynthesis of ZnO nanoparticles (Zn NPs) using latex of C. papaya as an effective reducing agent. Green synthesis of nanoparticles has advantageous over conventional methods because it does not require the use of toxic chemicals and therefore environmentally sustainable. Zinc oxide nanoparticles have gained potential recognition because of their distinctive characteristics and wide utilizatrion in various fields. Properties of synthesized ZnO NPs were characterized using various methods such as ultra violet visible spectrophotometer (UV-Vis), Scanning Electron Microscopy (SEM) and Fourier Transform İnfrared Spectroscopy (FT-IR). The elemental composition of C. Papaya latex was also analysed using X-ray Fluorescence (XRF) technique. Green synthesized ZnO nanoparticles also assessed for its antimicrobial activity against selected bacterial species.
Anahtar Kelimeler
Antimicrobial activity carica papaya elemental composition latex ZnO NPs
Etik Beyan
No ethical issues exist.
Destekleyen Kurum
Centurion University of Technology and Management and CSIR-IMMT, Bhubaneswar
Proje Numarası
Not applicable
Teşekkür
Thanks for consideration.
Kaynakça
- D. Sharma, J. Rajput, B.S. Kaith, M. Kaur, S. Sharma, “Synthesis of ZnO nano particles and study of their antibacterial and antifungal properties,” Thin Solid Films, 519(3), pp. 1224–1229, 2010.
- G. Aravind, D. Bhowmik, S. Duraivel, and G. Harish, “Traditional and medicinal uses of Carica papaya. Journal of Medicinal Plants Studies,” 1(1), pp. 7-15, 2013.
- V. Yogiraj, P.K. Goyal, C.S. Chauhan, A. Goyal, and B. Vyas, “Carica papaya Linn: an overview. International Journal of Herbal Medicine,” 2(5), pp. 01-8, 2014.
- M. Chandrasekaran, S.M. Basheer, S. Chellappan, J.G. Krishna, P.S. Beena, “Enzymes in food and beverage production: an overview,” Enzym Food Beverage Process CRC Press, 25, pp. 133-154, 2015.
- S. Pandey, P.J. Cabot, P.N. Shaw, and A.K. Hewavitharana, “Anti-inflammatory and immunomodulatory properties of Carica papaya,” Journal of İmmunotoxicology, 13(4):590-602, 2016.
- C.J. Hewitt, S. R. Bellara, A. Andreani, G. Nebe-von-Caron, and C. M. McFarlane, “An evaluation of the anti-bacterial action of ceramic powder slurries using multi-parameter flow cytometry,” Biotechnology Letters, 2001.
- S. Makhluf, R. Dror, Y. Nitzan, Y. Abramovich, R. Jelinek, and A. Gedanken, “Microwave‐assisted synthesis of nanocrystalline MgO and its use as a bacteriocide,” Advanced Functional Materials. 15(10), pp. 1708-1715, 2005.
- R. Brayner, R. Ferrari-Iliou, N. Brivois, S. Djediat, M. F. Benedetti, and F. Fiévet, “Toxicological impact studies based on Escherichia coli bacteria in ultrafine ZnO nanoparticles colloidal medium,” Nano Letters, 6(4), pp. 866-870, 2016.
- N. G. Heatley, “A method for the assay of penicillin,” Biochemical Journal. 1944;38(1):61.
- Magaldi S, Mata-Essayag S, De Capriles CH, Pérez C, Colella MT, Olaizola C, and Ontiveros Y. , “Well diffusion for antifungal susceptibility testing,” International Journal of İnfectious Diseases, 8(1), pp. 39-45, 2004.
- C. Valgas, S. M. Souza, E.F. Smânia, and Jr. A. Smânia, “Screening methods to determine antibacterial activity of natural products,” Brazilian Journal of Microbiology. 2007;38, pp. 369-380, 2007.
- R. Sharma, R. Garg, and A. Kumari, “A review on biogenic synthesis, applications and toxicity aspects of zinc oxide nanoparticles,” EXCLI Journal, 19, pp. 1325, 2020.
- K. Sowri Babu, A. Ramachandra Reddy, C. Sujatha, K. Venugopal Reddy, and A. N. Mallika, “Synthesis and optical characterization of porous ZnO,” Journal of Advanced Ceramics, pp. 260-265, 2023.
- K.Y. Ong, H.S. Chin, and K.C. Teo, “Biological screening of microbes isolated from soil of ex-tin mining land in Kampar Area,” African Journal of Microbiology Research. 2011 Nov 23;5(27):4757-4763.
- A. Islam, M.A. Al-Mamun, S. Parvin, M. Sarker, M.K. Zaman, P. Farhana, Z. Shahriar, and M. Salah Uddin, “Evaluation of antibacterial activities of latex of Caricaceae (Carica papaya L.),” Asian Journal of Pharmaceutical and Clinical Research, 8(1), pp. 308-311, 2015.
- K. Maneesh, K. Vijayabhaskar, H. Firdouse, P.S. Rao, M. Prajwitha, and S. Swetha, “Evaluation of Antimicrobial of P. vesicularis, Streptococcus faecalis, Aeromonas hydrophilia, Salmonela typhae, Stphylococcus cohni, Serratia ficaria and E. coli. of crude and n-butanol fraction fruit latex of Carica papaya L.(Caricaceae),”Asian Journal of Pharmaceutical Research, 11(2), pp. 92-94, 2021.
- T. Vij, and Y. Prashar, “A review on medicinal properties of Carica papaya Linn.,” Asian Pacific Journal of Tropical Disease, 5(1), pp. 1-6, 2015.
- R. Ajani, and K. Ogunbiyi, “Carica papaya latex accelerates wound healing in diabetic wistar rats,” European Journal of Medicinal Plants, 9(3), pp. 1-2, 2015.
- M. Ancheta, and L. Acero, “Wound healing property of Carica papaya stem in albino rats,” International Jurnal of Bioscience, Biochemistry and Bioinfarmatics, 6(2), pp. 68-74, 2016.
- K.R. Raghupathi, R. T. Koodali, and A. C. Manna, “Size-dependent bacterial growth inhibition and mechanism of antibacterial activity of zinc oxide nanoparticles,” Langmuir. 5;27(7), pp. 4020-4028, 2011.
- B. L. da Silva, B. L. Caetano BL, B.G. Chiari-Andréo, R. C. Pietro, and L.A. Chiavacci, “Increased antibacterial activity of ZnO nanoparticles: Influence of size and surface modification,” Colloids and Surfaces B: Biointerfaces, 177, pp. 440-447, 2019.
- Q. U. Naqvi, A. Kanwal, S. Qaseem, M. Naeem, S. R. Ali, M. Shaffique, and M. Maqbool, “Size-dependent inhibition of bacterial growth by chemically engineered spherical ZnO nanoparticles,” Journal of Biological Physics, 45, pp. 147-159, 2019.
Öz
Proje Numarası
Not applicable
Kaynakça
- D. Sharma, J. Rajput, B.S. Kaith, M. Kaur, S. Sharma, “Synthesis of ZnO nano particles and study of their antibacterial and antifungal properties,” Thin Solid Films, 519(3), pp. 1224–1229, 2010.
- G. Aravind, D. Bhowmik, S. Duraivel, and G. Harish, “Traditional and medicinal uses of Carica papaya. Journal of Medicinal Plants Studies,” 1(1), pp. 7-15, 2013.
- V. Yogiraj, P.K. Goyal, C.S. Chauhan, A. Goyal, and B. Vyas, “Carica papaya Linn: an overview. International Journal of Herbal Medicine,” 2(5), pp. 01-8, 2014.
- M. Chandrasekaran, S.M. Basheer, S. Chellappan, J.G. Krishna, P.S. Beena, “Enzymes in food and beverage production: an overview,” Enzym Food Beverage Process CRC Press, 25, pp. 133-154, 2015.
- S. Pandey, P.J. Cabot, P.N. Shaw, and A.K. Hewavitharana, “Anti-inflammatory and immunomodulatory properties of Carica papaya,” Journal of İmmunotoxicology, 13(4):590-602, 2016.
- C.J. Hewitt, S. R. Bellara, A. Andreani, G. Nebe-von-Caron, and C. M. McFarlane, “An evaluation of the anti-bacterial action of ceramic powder slurries using multi-parameter flow cytometry,” Biotechnology Letters, 2001.
- S. Makhluf, R. Dror, Y. Nitzan, Y. Abramovich, R. Jelinek, and A. Gedanken, “Microwave‐assisted synthesis of nanocrystalline MgO and its use as a bacteriocide,” Advanced Functional Materials. 15(10), pp. 1708-1715, 2005.
- R. Brayner, R. Ferrari-Iliou, N. Brivois, S. Djediat, M. F. Benedetti, and F. Fiévet, “Toxicological impact studies based on Escherichia coli bacteria in ultrafine ZnO nanoparticles colloidal medium,” Nano Letters, 6(4), pp. 866-870, 2016.
- N. G. Heatley, “A method for the assay of penicillin,” Biochemical Journal. 1944;38(1):61.
- Magaldi S, Mata-Essayag S, De Capriles CH, Pérez C, Colella MT, Olaizola C, and Ontiveros Y. , “Well diffusion for antifungal susceptibility testing,” International Journal of İnfectious Diseases, 8(1), pp. 39-45, 2004.
- C. Valgas, S. M. Souza, E.F. Smânia, and Jr. A. Smânia, “Screening methods to determine antibacterial activity of natural products,” Brazilian Journal of Microbiology. 2007;38, pp. 369-380, 2007.
- R. Sharma, R. Garg, and A. Kumari, “A review on biogenic synthesis, applications and toxicity aspects of zinc oxide nanoparticles,” EXCLI Journal, 19, pp. 1325, 2020.
- K. Sowri Babu, A. Ramachandra Reddy, C. Sujatha, K. Venugopal Reddy, and A. N. Mallika, “Synthesis and optical characterization of porous ZnO,” Journal of Advanced Ceramics, pp. 260-265, 2023.
- K.Y. Ong, H.S. Chin, and K.C. Teo, “Biological screening of microbes isolated from soil of ex-tin mining land in Kampar Area,” African Journal of Microbiology Research. 2011 Nov 23;5(27):4757-4763.
- A. Islam, M.A. Al-Mamun, S. Parvin, M. Sarker, M.K. Zaman, P. Farhana, Z. Shahriar, and M. Salah Uddin, “Evaluation of antibacterial activities of latex of Caricaceae (Carica papaya L.),” Asian Journal of Pharmaceutical and Clinical Research, 8(1), pp. 308-311, 2015.
- K. Maneesh, K. Vijayabhaskar, H. Firdouse, P.S. Rao, M. Prajwitha, and S. Swetha, “Evaluation of Antimicrobial of P. vesicularis, Streptococcus faecalis, Aeromonas hydrophilia, Salmonela typhae, Stphylococcus cohni, Serratia ficaria and E. coli. of crude and n-butanol fraction fruit latex of Carica papaya L.(Caricaceae),”Asian Journal of Pharmaceutical Research, 11(2), pp. 92-94, 2021.
- T. Vij, and Y. Prashar, “A review on medicinal properties of Carica papaya Linn.,” Asian Pacific Journal of Tropical Disease, 5(1), pp. 1-6, 2015.
- R. Ajani, and K. Ogunbiyi, “Carica papaya latex accelerates wound healing in diabetic wistar rats,” European Journal of Medicinal Plants, 9(3), pp. 1-2, 2015.
- M. Ancheta, and L. Acero, “Wound healing property of Carica papaya stem in albino rats,” International Jurnal of Bioscience, Biochemistry and Bioinfarmatics, 6(2), pp. 68-74, 2016.
- K.R. Raghupathi, R. T. Koodali, and A. C. Manna, “Size-dependent bacterial growth inhibition and mechanism of antibacterial activity of zinc oxide nanoparticles,” Langmuir. 5;27(7), pp. 4020-4028, 2011.
- B. L. da Silva, B. L. Caetano BL, B.G. Chiari-Andréo, R. C. Pietro, and L.A. Chiavacci, “Increased antibacterial activity of ZnO nanoparticles: Influence of size and surface modification,” Colloids and Surfaces B: Biointerfaces, 177, pp. 440-447, 2019.
- Q. U. Naqvi, A. Kanwal, S. Qaseem, M. Naeem, S. R. Ali, M. Shaffique, and M. Maqbool, “Size-dependent inhibition of bacterial growth by chemically engineered spherical ZnO nanoparticles,” Journal of Biological Physics, 45, pp. 147-159, 2019.
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Konular | Temiz Üretim Teknolojileri, Çevresel ve Sürdürülebilir Süreçler, Halk Sağlığı (Diğer) |
| Bölüm | Research Articles |
| Yazarlar | |
| Proje Numarası | Not applicable |
| Yayımlanma Tarihi | 30 Haziran 2025 |
| Gönderilme Tarihi | 17 Mayıs 2024 |
| Kabul Tarihi | 1 Ekim 2024 |
| Yayımlandığı Sayı | Yıl 2025 Cilt: 8 Sayı: 2 |
