A Review on Calcium-alginate microspheres for Drug Delivery System: Characteristics, Drug Release, Activity, Stability and In Vivo Studies
Öz
Microspheres are one of drug delivery system which allow therapeutic agents to penetrate into the body in order to increase their efficacy and safety by regulating their rate of release, timing and site of action in the body. Alginate is a natural polymer of polysaccharides which has the advantages of biocompatible, low toxicity, inexpensive, easy to obtain, capable of chemical modifications. Calcium chloride is the most suitable crosslinker for sodium alginate. Researchs on calcium-alginate microspheres has been widely developed for the delivery of various drugs. Therefore, this review provides a comprehensive summary of research focusing on the in vitro (drug release, activity), stability and in vivo studies of calcium-alginate microspheres for drug delivery.
Anahtar Kelimeler
microspheres alginate calcium chloride in vitro stability in vivo
Kaynakça
- Amiruddin, Muh. Agus Syamsur Rijal, & Dewi Melani Hariyadi. (2023). Effect of CaCl2 Crosslinker Concentration On The Characteristics, Release, and Stability of Ciprofloxacin HCl-AlginateCarrageenan Microspheres. Jurnal Farmasi Dan Ilmu Kefarmasian Indonesia, 10(3), 312–323
A Review on Calcium-alginate microspheres for Drug Delivery System: Characteristics, Drug Release, Activity, Stability and In Vivo Studies
Öz
Kaynakça
- Amiruddin, Muh. Agus Syamsur Rijal, & Dewi Melani Hariyadi. (2023). Effect of CaCl2 Crosslinker Concentration On The Characteristics, Release, and Stability of Ciprofloxacin HCl-AlginateCarrageenan Microspheres. Jurnal Farmasi Dan Ilmu Kefarmasian Indonesia, 10(3), 312–323
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Konular | İlaç Dağıtım Teknolojileri |
| Bölüm | Derleme |
| Yazarlar | |
| Yayımlanma Tarihi | 25 Mart 2025 |
| Gönderilme Tarihi | 6 Temmuz 2024 |
| Kabul Tarihi | 27 Kasım 2024 |
| Yayımlandığı Sayı | Yıl 2025 |