Olgu Sunumu
Yıl 2024,
Cilt: 4 Sayı: 3, 119 - 122, 31.12.2024
Öz
Ağız boşluğunda nadir görülen Diffüz Büyük B Hücreli Lenfoma (DLBCL) benign lezyonlara benzerliği nedeniyle teşhis açısından zorluk oluşturur. Bu raporda 58 yaşındaki bir kadın hastada mandibulanın anterior bölgede giderek büyüyen asemptomatik bir şişlik olarak ortaya çıkan bir DLBCL olgusu sunulmaktadır. Ön tanıda benign lezyon olarak düşünülmesine rağmen eksizyonel biyopsi sonrası yapılan histopatolojik incelemede DLBCL olarak teşhis konulmuştur. Bu vaka, ağız boşluğundaki şişliklerin ayırıcı tanısında DLBCL'yi düşünmenin önemini vurgulamakta ve tanının ve tedavinin hızlı bir şekilde yapılmasının önemini vurgulamaktadır.
Kaynakça
- 1. Swerdlow SH, Campo E, Pileri SA, et al. The 2016 revision of the World Health Organization classification of lymphoid neoplasms. Blood. 2016; 127(20):2375-2390.
- 2. Epstein JB, Epstein JD, Le ND, Gorsky M. Characteristics of oral and paraoral malignant lymphoma: a population-based review of 361 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2001;92(5):519-25.
- 3. Vannata B, Zucca E. Primary extranodal B-cell lymphoma: current concepts and treatment strategies. Chin Clin Oncol 2015;4:10.
- 4. Kolokotronis A, Konstantinou N, Christakis I, Papadimitriou P, Matiakis A, Zaraboukas T, et al. Localized B-cell non-Hodgkin’s lymphoma of oral cavity and maxillofacial region: A clinical study.Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2005;99:303-10.
- 5. Roschewski M, Staudt LM, Wilson WH. Diffuse large B-cell lymphoma—treatment approaches in the molecular era. Nat Rev Clin Oncol. 2014;11(1):12-23.
- 6. Pereira DL, Fernandes DT, Santos-Silva AR, et al. Intraosseous non-Hodgkin lymphoma mimicking a periapical lesion. J Endod 2015;41:1738–42.
- 7. Gustavsson, A., Osterman, B., & Cavallin-ståhl, E. (2003). A systematic overview of radiation therapy effects in Non-Hodgkin’s Lymphoma. Acta Oncologica, 42(5–6), 605–619.
- 8. Sağnak Yılmaz, Z., & Çobanoğlu, Ü. (2020). Distribution of lymphoid neoplasms in northeast Turkey: A retrospective analysis of 1136 cases according to the World Health Organization Classification. Konuralp Tıp Dergisi, 12(2), 208–215.
- 9. Guevara-Canales JO, Morales-Vadillo R, Sacsaquispe-Contreras SJ, et al. Malignant lymphoma of the oral cavity and the maxillofacial region: overall survival prognostic factors. Med Oral Patol Oral Cir Bucal 2013;18:e619–26.
- 10. Kirita, T., Ohgi, K., Shimooka, H., Okamoto, M., Yamanaka, Y., & Sugimura, M. (2000). Primary non-hodgkin’s lymphoma of the mandible treated with radiotherapy, chemotherapy, and autologous peripheral blood stem cell transplantation. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 90(4), 450–455.
- 11. Rinaggio J, Aguirre A, Zeid M, Hatton MN. Swelling of nasolabial area. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2000;89:669-73.
- 12. Neville BW: Oral and Maxillofacial Pathology, ed 3. St. Louis, Saunders/Elsevier, 2009.
- 13. Bugshan, A., Kassolis, J., & Basile, J. (2015). Primary diffuse large B-cell lymphoma of the mandible: Case report and review of the literature. Case Reports in Oncology, 8(3), 451–455.
- 14. Regezi JA, Sciubba JJ, Jordan RCK: Oral Pathology: Clinical Pathologic Correlations. St. Louis, Saunders/Elsevier, 2008.
- 15. Jiang M, Bennani NN, Feldman AL. Lymphoma classification update: Bcell non-Hodgkin lymphomas. Expert Rev Hematol 2017;10:405–15
- 16. Zou, H., Yang, H., Zou, Y., Lei, L., & Song, L. (2018). Primary diffuse large B-cell lymphoma in the maxilla: a case report. Medicine, 97(20), e10707.
- 17. Jayapalan, C. S., Pynadath, M. K., Mangalath, U., George, A., Aslam, S., & Hafiz, A. (2016). Clinical diagnostic dilemma in an uncharacteristic rapidly enlarging swelling of the anterior maxilla: extranodal diffuse large B-cell lymphoma. Case Reports, 2016, bcr2015213141.
- 18. Vodicka, P., Klener, P., & Trneny, M. (2022). Diffuse large B-cell lymphoma (DLBCL): Early patient management and emerging treatment options. OncoTargets and Therapy, Volume 15, 1481–1501.
- 19. Triantafillidou K, Dimitrakopoulos J, Iordanidis F, Gkagkalis A. Extranodal non-hodgkin lymphomas of the oral cavity and maxillofacial region: a clinical study of 58 cases and review of the literature. J Oral Maxillofac Surg 2012;70:2776–85.
Yıl 2024,
Cilt: 4 Sayı: 3, 119 - 122, 31.12.2024
Öz
Diffuse Large B Cell Lymphoma (DLBCL), which is rare in the oral cavity, poses diagnostic challenges due to its similarity to benign lesions. In this report, a case of DLBCL presenting as an asymptomatic swelling in the anterior region of the mandible that gradually grows in a 58-year-old female patient is presented. Although it was thought to be a benign lesion in the preliminary diagnosis, it was diagnosed as DLBCL in the histopathological examination performed after excisional biopsy. This case highlights the importance of considering DLBCL in the differential diagnosis of swellings in the oral cavity and emphasizes the importance of making the diagnosis and treatment quickly.
Kaynakça
- 1. Swerdlow SH, Campo E, Pileri SA, et al. The 2016 revision of the World Health Organization classification of lymphoid neoplasms. Blood. 2016; 127(20):2375-2390.
- 2. Epstein JB, Epstein JD, Le ND, Gorsky M. Characteristics of oral and paraoral malignant lymphoma: a population-based review of 361 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2001;92(5):519-25.
- 3. Vannata B, Zucca E. Primary extranodal B-cell lymphoma: current concepts and treatment strategies. Chin Clin Oncol 2015;4:10.
- 4. Kolokotronis A, Konstantinou N, Christakis I, Papadimitriou P, Matiakis A, Zaraboukas T, et al. Localized B-cell non-Hodgkin’s lymphoma of oral cavity and maxillofacial region: A clinical study.Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2005;99:303-10.
- 5. Roschewski M, Staudt LM, Wilson WH. Diffuse large B-cell lymphoma—treatment approaches in the molecular era. Nat Rev Clin Oncol. 2014;11(1):12-23.
- 6. Pereira DL, Fernandes DT, Santos-Silva AR, et al. Intraosseous non-Hodgkin lymphoma mimicking a periapical lesion. J Endod 2015;41:1738–42.
- 7. Gustavsson, A., Osterman, B., & Cavallin-ståhl, E. (2003). A systematic overview of radiation therapy effects in Non-Hodgkin’s Lymphoma. Acta Oncologica, 42(5–6), 605–619.
- 8. Sağnak Yılmaz, Z., & Çobanoğlu, Ü. (2020). Distribution of lymphoid neoplasms in northeast Turkey: A retrospective analysis of 1136 cases according to the World Health Organization Classification. Konuralp Tıp Dergisi, 12(2), 208–215.
- 9. Guevara-Canales JO, Morales-Vadillo R, Sacsaquispe-Contreras SJ, et al. Malignant lymphoma of the oral cavity and the maxillofacial region: overall survival prognostic factors. Med Oral Patol Oral Cir Bucal 2013;18:e619–26.
- 10. Kirita, T., Ohgi, K., Shimooka, H., Okamoto, M., Yamanaka, Y., & Sugimura, M. (2000). Primary non-hodgkin’s lymphoma of the mandible treated with radiotherapy, chemotherapy, and autologous peripheral blood stem cell transplantation. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology, 90(4), 450–455.
- 11. Rinaggio J, Aguirre A, Zeid M, Hatton MN. Swelling of nasolabial area. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2000;89:669-73.
- 12. Neville BW: Oral and Maxillofacial Pathology, ed 3. St. Louis, Saunders/Elsevier, 2009.
- 13. Bugshan, A., Kassolis, J., & Basile, J. (2015). Primary diffuse large B-cell lymphoma of the mandible: Case report and review of the literature. Case Reports in Oncology, 8(3), 451–455.
- 14. Regezi JA, Sciubba JJ, Jordan RCK: Oral Pathology: Clinical Pathologic Correlations. St. Louis, Saunders/Elsevier, 2008.
- 15. Jiang M, Bennani NN, Feldman AL. Lymphoma classification update: Bcell non-Hodgkin lymphomas. Expert Rev Hematol 2017;10:405–15
- 16. Zou, H., Yang, H., Zou, Y., Lei, L., & Song, L. (2018). Primary diffuse large B-cell lymphoma in the maxilla: a case report. Medicine, 97(20), e10707.
- 17. Jayapalan, C. S., Pynadath, M. K., Mangalath, U., George, A., Aslam, S., & Hafiz, A. (2016). Clinical diagnostic dilemma in an uncharacteristic rapidly enlarging swelling of the anterior maxilla: extranodal diffuse large B-cell lymphoma. Case Reports, 2016, bcr2015213141.
- 18. Vodicka, P., Klener, P., & Trneny, M. (2022). Diffuse large B-cell lymphoma (DLBCL): Early patient management and emerging treatment options. OncoTargets and Therapy, Volume 15, 1481–1501.
- 19. Triantafillidou K, Dimitrakopoulos J, Iordanidis F, Gkagkalis A. Extranodal non-hodgkin lymphomas of the oral cavity and maxillofacial region: a clinical study of 58 cases and review of the literature. J Oral Maxillofac Surg 2012;70:2776–85.
Toplam 19 adet kaynakça vardır.
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Konular | Ağız, Yüz ve Çene Cerrahisi, Oral Tıp ve Patoloji |
| Bölüm | Olgu Sunumları |
| Yazarlar | |
| Erken Görünüm Tarihi | 31 Aralık 2024 |
| Yayımlanma Tarihi | 31 Aralık 2024 |
| Gönderilme Tarihi | 27 Mayıs 2024 |
| Kabul Tarihi | 28 Kasım 2024 |
| Yayımlandığı Sayı | Yıl 2024 Cilt: 4 Sayı: 3 |
