Araştırma Makalesi
The Relationship Between Anticipatory Nausea and Vomiting with Social Support and Anxiety in Cancer Patients Undergoing Chemotherapy
Öz
Abstract
Purpose: This study aims to investigate the relationship between anticipatory nausea and vomiting in
cancer patients undergoing chemotherapy with social support and anxiety.
Material and Methods: This descriptive-correlational study involved 134 cancer patients receiving
chemotherapy at a university hospital and experiencing anticipatory nausea. Anxiety levels were
measured using the Beck Anxiety Inventory (BAI), while the severity of nausea was assessed using
the Visual Analog Scale (VAS-nausea), and social support levels were evaluated using the Cancer
Patient Social Support Scale (CPSSS). Descriptive statistics were employed to analyze demographic
characteristics. Independent sample t-tests, Kruskal-Wallis, one-way analysis of variance (ANOVA),
Mann-Whitney U test, Cronbach's alpha coefficient, and Pearson correlation analysis were used for
data analysis.
Results: Results showed that 62.7% experienced moderate to severe nausea post-chemotherapy,
with 57.5% having received prior chemotherapy. 61.2% reported minimal anxiety. Patients under
moderately emetogenic treatments exhibited higher anticipatory nausea scores. Anxiety inversely
correlated with social support, but no significant link was found between anticipatory nausea severity
and anxiety/social support levels.
Conclusion: The findings indicate that there is no relationship between anticipatory nausea and
vomiting, social support, and anxiety among cancer patients undergoing chemotherapy.
Anahtar Kelimeler
Cancer chemotherapy anticipatory nausea and vomiting anxiety social support
Kaynakça
- Mosa A, Hossain A, Lavoie B, Yoo I. Patient-Related Risk Factorsfor Chemotherapy Induced Nausea and Vomiting: A Systematic Review. Frontiers in Pharmacology 2020;11(329):1-3
- Dranitsaris G, Molassiotis A, Clemons M, Roeland E, Schwartzberg L, Dielenseger P et al. The development of a prediction tool to identify cancer patients at high risk for chemotherapy-induced nausea and vomiting. Ann. Oncol 2017;28(6):1260-1267.
- Natale J. Overview of the prevention and management of CINV. Am J Manag Care 2018; 24(18):391-397.
- Margulies A, Jahn P, Eriksson A, Torcato S, Vidall C. Clinical Practice Guidance for Nurses, Cancer Therapy-Induced Nausea&Vomiting in Adults. EONS: European Oncology Nursing Society 2019:1-27
- Sun Y, Zheng Y, Yang X, Xie K, Du C, He L et al. Prevalence of chemotherapy-induced nausea and vomiting among cancer patients receiving moderately to highly emetogenic chemotherapy at cancer centers in Sichuan, China. Journal of Cancer Research and Clinical Oncology 2021;147:2701-2708.
- Buluş M. Onkoloji Hemşireliği: Bulantı Kusma. İstanbul: Nobel Kitapevi;2015.
- National Cancer Institue: NCI [web]. 2020 [Erişim Tarihi: 05.09.2021]. Erişim adresi:https://www.cancer.gov/about-cancer/treatment/side-effects/nausea/nausea pdq
- Molassiotis A, Lee P, Burke T, Dicato M, Gascon P, Roila F ve ark. Anticipatory Nausea, Risk Factors, and Its Impact on Chemotherapy-Induced Nausea and Vomiting: Results From the Pan European Emesis Registry Study. J Pain Symptom Manage 2016;51(6):93-987
- Roscoe J, Morrow G, Aapro M, Molassiotis A, Olver I. Anticipatory nausea and vomiting. Support Care Cancer 2011;19(10):8-1533.
- Kamen C, Tejani M, Chandwani K, Janelsins M, Peoples A, Roscoe J ve ark. Anticipatory nausea and vomiting due to chemotherapy. European Journal of Pharmacology 2014;722:9- 172.
- Hickok J, Roscoe J, Morrow G. The role of patients' expectations in the development of anticipatory nausea related to chemotherapy for cancer. J Pain Symptom Manage 2001;22(4):50-843.
- Montgomery G, Bovbjerg D. Expectations of chemotherapy-related nausea: emotional and experiential predictors. Ann Behav Med 2003;25(1):48-54.
- Aapro M, Molassiotis A, Olver I. Anticipatory nausea and vomiting. Support Care Cancer 2005;13(2):21-117.
- Yıldızeli S, ErgülB. Cerrahi Girişim Bekleyen Kolorektal Kanser Hastalarında Sosyal Destek Algısı ve Etkileyen Faktörler. Süleyman Demirel Üniversitesi Sağlık Bilimleri Dergisi 2019;10(4):423-430.
- Duci V, Tahsini I. Perceived social support and coping styles as moderators for levels of anxiety, depression and quality of life in cancer caregivers; a literature review. Eur Sci J 2010;8(11):160- 171.
- Kim Y, Morrow G. The effects of family support, anxiety, and post-treatment nausea on the development of anticipatory nausea: a latent growth model. J Pain Symptom Manage 2007;34(3):76-265.
- Kim Y, Morrow G. Changes in family relationships affect the development of chemotherapy- related nausea symptoms. Support Care Cancer 2003;11(3):7-171.
- Wen S, Xiao H, Yang Y. The risk factors for depression in cancer patients undergoing chemotherapy: a systematic review. Support Care Cancer. 2019;27(1):57–67.
- Baker P, Morzorati S, Ellett M. Pathophysiology of Chemotherapy-Indured Nausea and Vomiting. Gastroenterology Nursing. 2005;28(6):80-469.
- Ulusoy M, Şahin N, Erkman H. Turkish version of the beck anxiety ınventory: psychometric properties. J Cognitive Psychotherapy: Int Quaterly 1998;12:28-35.
- Eylen B. Kanser Hastası Sosyal Destek Ölçeği" nin Geçerlik, Güvenirlik ve Faktör Yapısı Üzerine Bir Çalışma. Uludağ Üniversitesi Eğitim Fakültesi Dergisi 2002;15(1):109-117.
- Lua PL, Salihah N, Mazlan N. Effects of inhaled ginger aromatherapy on chemotherapy-induced nausea and vomiting and healtj-related quality of life in women with breast cancer. Complementary Therapies in Medicine 2015;23(3):396-404.
- Yeo W, Mo FK, Suen JJ, Ho WM, Chan SL, Lau W ve ark. A randomized study of aprepitant, ondansetron, and dexamethasone for chemotherapy-induced nausea and vomiting in Chinese breast cancer patients receiving moderately emetogenic chemotherapy. Breast Cancer Res Treat 2009;113(3):35-529
- IBM Corp. Released 2017. IBM SPSS Statistics for Windows, Version 25.0. Armonk, NY: IBM Corp.
- James A, Nair M, Abraham D, Kovoor J, Jose W, Reghu R. Effect of Lorazepam in Reducing Psychological Distress and Anticipatory Nausea and Vomiting in Patients Undergoing Chemotherapy. J Pharmacol Pharmacother 2017;8(3):112-115.
- Hunter JJ, Maunder RG, Sui D, Esplen MJ, Chaoul A, Fisch MJ et al. A randomized trial of nurse-administered behavioral interventions to manage anticipatory nausea and vomiting in chemotherapy. Cancer Med 2020;9(5):1733-1740.
- Akechi T, Okuyama T, Endo C, Sagawa R, Uchida M, Nakaguchi T et al. Anticipatory nausea among ambulatory cancer patients undergoing chemotherapy: prevalence, associated factors, and impact on quality of life. Cancer Sci 2010;101(12): 600-2596.
- Ruzsa A, Lelovics Z, Hegedűs K. A nem és az iskolázottság hatása a kemoterápia indukálta anticipátoros hányinger, hányás kialakulására. Orv Hetil 2013;154(21):4-820.
- Chan A, Kim HK, Hsieh RK, Yu S, Su WC, Baños A et al. Incidence and predictors of anticipatory nausea and vomiting in Asia Pacific clinical practice a longitudinal analysis. Support Care Cancer. 2015;23(1):283-291.
- Sari DK, Dewi R, Daulay W. Association Between Family Support, Coping Strategies and Anxiety in Cancer Patients Undergoing Chemotherapy at General Hospital in Medan, North Sumatera, Indonesia. Asian Pac J Cancer Prev 2019;20(10):3015-3019.
- Naser AY, Hameed AN, Mustafa N, Alwafi H, Dahmash EZ, Alyami HS et al. Depression and Anxiety in Patients With Cancer: A Cross-Sectional Study. Front Psychol 2021;12:585534.
- Pandey M, Sarita GP, Devi N, Thomas BC, Hussain BM, Krishnan R. Distress, anxiety, and depression in cancer patients undergoing chemotherapy. World J Surg Oncol 2006;4:68.
- Kurt B. Adjuvan Kemoterapi Tedavisi Alan Meme Kanserli Hastalarda Oral Kriyoterapi Uygulamasının Beklentisel, Akut ve Geç Bulantı Kusmaya Etkisi [Ph.D. thesis]. Ankara: Hacettepe Üniversity; 2021
The Relationship Between Anticipatory Nausea and Vomiting with Social Support and Anxiety in Cancer Patients Undergoing Chemotherapy
Öz
Kaynakça
- Mosa A, Hossain A, Lavoie B, Yoo I. Patient-Related Risk Factorsfor Chemotherapy Induced Nausea and Vomiting: A Systematic Review. Frontiers in Pharmacology 2020;11(329):1-3
- Dranitsaris G, Molassiotis A, Clemons M, Roeland E, Schwartzberg L, Dielenseger P et al. The development of a prediction tool to identify cancer patients at high risk for chemotherapy-induced nausea and vomiting. Ann. Oncol 2017;28(6):1260-1267.
- Natale J. Overview of the prevention and management of CINV. Am J Manag Care 2018; 24(18):391-397.
- Margulies A, Jahn P, Eriksson A, Torcato S, Vidall C. Clinical Practice Guidance for Nurses, Cancer Therapy-Induced Nausea&Vomiting in Adults. EONS: European Oncology Nursing Society 2019:1-27
- Sun Y, Zheng Y, Yang X, Xie K, Du C, He L et al. Prevalence of chemotherapy-induced nausea and vomiting among cancer patients receiving moderately to highly emetogenic chemotherapy at cancer centers in Sichuan, China. Journal of Cancer Research and Clinical Oncology 2021;147:2701-2708.
- Buluş M. Onkoloji Hemşireliği: Bulantı Kusma. İstanbul: Nobel Kitapevi;2015.
- National Cancer Institue: NCI [web]. 2020 [Erişim Tarihi: 05.09.2021]. Erişim adresi:https://www.cancer.gov/about-cancer/treatment/side-effects/nausea/nausea pdq
- Molassiotis A, Lee P, Burke T, Dicato M, Gascon P, Roila F ve ark. Anticipatory Nausea, Risk Factors, and Its Impact on Chemotherapy-Induced Nausea and Vomiting: Results From the Pan European Emesis Registry Study. J Pain Symptom Manage 2016;51(6):93-987
- Roscoe J, Morrow G, Aapro M, Molassiotis A, Olver I. Anticipatory nausea and vomiting. Support Care Cancer 2011;19(10):8-1533.
- Kamen C, Tejani M, Chandwani K, Janelsins M, Peoples A, Roscoe J ve ark. Anticipatory nausea and vomiting due to chemotherapy. European Journal of Pharmacology 2014;722:9- 172.
- Hickok J, Roscoe J, Morrow G. The role of patients' expectations in the development of anticipatory nausea related to chemotherapy for cancer. J Pain Symptom Manage 2001;22(4):50-843.
- Montgomery G, Bovbjerg D. Expectations of chemotherapy-related nausea: emotional and experiential predictors. Ann Behav Med 2003;25(1):48-54.
- Aapro M, Molassiotis A, Olver I. Anticipatory nausea and vomiting. Support Care Cancer 2005;13(2):21-117.
- Yıldızeli S, ErgülB. Cerrahi Girişim Bekleyen Kolorektal Kanser Hastalarında Sosyal Destek Algısı ve Etkileyen Faktörler. Süleyman Demirel Üniversitesi Sağlık Bilimleri Dergisi 2019;10(4):423-430.
- Duci V, Tahsini I. Perceived social support and coping styles as moderators for levels of anxiety, depression and quality of life in cancer caregivers; a literature review. Eur Sci J 2010;8(11):160- 171.
- Kim Y, Morrow G. The effects of family support, anxiety, and post-treatment nausea on the development of anticipatory nausea: a latent growth model. J Pain Symptom Manage 2007;34(3):76-265.
- Kim Y, Morrow G. Changes in family relationships affect the development of chemotherapy- related nausea symptoms. Support Care Cancer 2003;11(3):7-171.
- Wen S, Xiao H, Yang Y. The risk factors for depression in cancer patients undergoing chemotherapy: a systematic review. Support Care Cancer. 2019;27(1):57–67.
- Baker P, Morzorati S, Ellett M. Pathophysiology of Chemotherapy-Indured Nausea and Vomiting. Gastroenterology Nursing. 2005;28(6):80-469.
- Ulusoy M, Şahin N, Erkman H. Turkish version of the beck anxiety ınventory: psychometric properties. J Cognitive Psychotherapy: Int Quaterly 1998;12:28-35.
- Eylen B. Kanser Hastası Sosyal Destek Ölçeği" nin Geçerlik, Güvenirlik ve Faktör Yapısı Üzerine Bir Çalışma. Uludağ Üniversitesi Eğitim Fakültesi Dergisi 2002;15(1):109-117.
- Lua PL, Salihah N, Mazlan N. Effects of inhaled ginger aromatherapy on chemotherapy-induced nausea and vomiting and healtj-related quality of life in women with breast cancer. Complementary Therapies in Medicine 2015;23(3):396-404.
- Yeo W, Mo FK, Suen JJ, Ho WM, Chan SL, Lau W ve ark. A randomized study of aprepitant, ondansetron, and dexamethasone for chemotherapy-induced nausea and vomiting in Chinese breast cancer patients receiving moderately emetogenic chemotherapy. Breast Cancer Res Treat 2009;113(3):35-529
- IBM Corp. Released 2017. IBM SPSS Statistics for Windows, Version 25.0. Armonk, NY: IBM Corp.
- James A, Nair M, Abraham D, Kovoor J, Jose W, Reghu R. Effect of Lorazepam in Reducing Psychological Distress and Anticipatory Nausea and Vomiting in Patients Undergoing Chemotherapy. J Pharmacol Pharmacother 2017;8(3):112-115.
- Hunter JJ, Maunder RG, Sui D, Esplen MJ, Chaoul A, Fisch MJ et al. A randomized trial of nurse-administered behavioral interventions to manage anticipatory nausea and vomiting in chemotherapy. Cancer Med 2020;9(5):1733-1740.
- Akechi T, Okuyama T, Endo C, Sagawa R, Uchida M, Nakaguchi T et al. Anticipatory nausea among ambulatory cancer patients undergoing chemotherapy: prevalence, associated factors, and impact on quality of life. Cancer Sci 2010;101(12): 600-2596.
- Ruzsa A, Lelovics Z, Hegedűs K. A nem és az iskolázottság hatása a kemoterápia indukálta anticipátoros hányinger, hányás kialakulására. Orv Hetil 2013;154(21):4-820.
- Chan A, Kim HK, Hsieh RK, Yu S, Su WC, Baños A et al. Incidence and predictors of anticipatory nausea and vomiting in Asia Pacific clinical practice a longitudinal analysis. Support Care Cancer. 2015;23(1):283-291.
- Sari DK, Dewi R, Daulay W. Association Between Family Support, Coping Strategies and Anxiety in Cancer Patients Undergoing Chemotherapy at General Hospital in Medan, North Sumatera, Indonesia. Asian Pac J Cancer Prev 2019;20(10):3015-3019.
- Naser AY, Hameed AN, Mustafa N, Alwafi H, Dahmash EZ, Alyami HS et al. Depression and Anxiety in Patients With Cancer: A Cross-Sectional Study. Front Psychol 2021;12:585534.
- Pandey M, Sarita GP, Devi N, Thomas BC, Hussain BM, Krishnan R. Distress, anxiety, and depression in cancer patients undergoing chemotherapy. World J Surg Oncol 2006;4:68.
- Kurt B. Adjuvan Kemoterapi Tedavisi Alan Meme Kanserli Hastalarda Oral Kriyoterapi Uygulamasının Beklentisel, Akut ve Geç Bulantı Kusmaya Etkisi [Ph.D. thesis]. Ankara: Hacettepe Üniversity; 2021
Toplam 33 adet kaynakça vardır.
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Konular | Klinik Onkoloji |
| Bölüm | Research Article |
| Yazarlar | |
| Yayımlanma Tarihi | 31 Ocak 2025 |
| Gönderilme Tarihi | 22 Ocak 2024 |
| Kabul Tarihi | 5 Kasım 2024 |
| Yayımlandığı Sayı | Yıl 2025 Cilt: 9 Sayı: 1 |
