Konferans Bildirisi
BibTex RIS Kaynak Göster

DRUGS AFFECTING NEWBORN WEIGHT, LENGTH AND HEAD CIRCUMFERENCE AT BIRTH

Yıl 2023, Cilt: 27 Sayı: Current Research Topıcs In Pharmacy: Pharmacology Debates, 10 - 14, 28.06.2025

Miloš N. Milosavljević , Jovana Milosavljević Ana V. Pejčić , Petar Arsenijević Ivana živanović Mačužić Nevena Folić Slobodan Janković

Öz

We designed our research as an ambidirectional cohort study that was conducted on the population of pregnant women whose pregnancy was monitored at the Clinic for Gynecology and Obstetrics of the University Clinical Centre Kragujevac, Serbia. All pregnant women with pregnancies confirmed by a gynecology specialist were taken into account, with the exception of pregnant women under the age of 18, functionally illiterate pregnant women and those with a confirmed high risk of genetic abnormalities of the fetus by a combination of ultrasound and biochemical examination during the 12th week of pregnancy. Our major outcome measures were body weight, body length and head circumference of newborns at birth. We examined the potential impact of the following variables to the newborn body size: demographic factors, presence of acute or chronic diseases during pregnancy, medications used during pregnancy, pregnancy factors, presence of uterine or placental abnormalities and maternal nutrition. For the assessment of the nutritional status of pregnant women, we previously developed and validated a special questionnaire that we named Balkan Food Quality and Diversity in Pregnancy Questionnaire-18 (BFQDPQ-18) [6]. We used the method of multiple linear regression analysis to evaluate the influence of potential factors on birth weight, length, and head circumference.

Anahtar Kelimeler

Newborn birth size birth weight birth lenght birth head circumference drugs

Kaynakça

  • [1] Kheirouri S, Alizadeh M. Impact of prenatal maternal factors and birth order on the anthropometric status of newborns in Iran. J Biosoc Sci. 2017; 49(2): 251-264. [CrossRef]
  • [2] Zeljkovic A, Vekic J, Spasic S, Jelic-Ivanovic Z, Spasojevic-Kalimanovska V, Gojkovic T, Ardalic D, Mandic-Markovic V, Cerovic N, Mikovic Z. Changes in LDL and HDL subclasses in normal pregnancy and associations with birth weight, birth length and head circumference. Matern Child Health J. 2013; 17(3): 556-565. [CrossRef]
  • [3] Lunde A, Melve KK, Gjessing HK, Skjaerven R, Irgens LM. Genetic and environmental influences on birth weight, birth length, head circumference, and gestational age by use of population-based parent-offspring data. Am J Epidemiol. 2007; 165(7): 734-741. [CrossRef]
  • [4] Parazzini F, Benedetto C, Bortolus R. Nifedipine versus expectant management in mild to moderate hypertension in pregnancy. Br J Obstet Gynaecol. 1998; 105(7): 718–722. [CrossRef]
  • [5] Karahanoglu E, Altinboga O, Akpinar F, Demirdag E, Ozdemirci S, Akyol A, Yalvac S. Nifedipine increases fetoplacental perfusion. J Perinat Med. 2017; 45(1): 51-55. [CrossRef]
  • [6] Milosavljević J, Pejčić A, Arsenijević P, Dimitrijević A, Milosavljević M, Mihajlović D, Janković S. Testing of new instrument for measuring quality and diversity of nutrition in pregnancy. Ginekol Pol. 2023; 94(1): 73-78. [CrossRef]
  • [7] Kemp MW, Newnham JP, Challis JG, Jobe AH, Stock SJ. The clinical use of corticosteroids in pregnancy. Hum Reprod Update. 2016; 22(2): 240-259. [CrossRef]
  • [8] Crowther CA, McKinlay CJ, Middleton P, Harding JE. Repeat doses of prenatal corticosteroids for women at risk of preterm birth for improving neonatal health outcomes. Cochrane Database Syst Rev. 2015; 2015(7): CD003935. [CrossRef]
  • [9] Rodriguez A, Wang Y, Ali Khan A, Cartwright R, Gissler M, Järvelin MR. Antenatal corticosteroid therapy (ACT) and size at birth: A population-based analysis using the Finnish Medical Birth Register. PLoS Med. 2019; 16(2): e1002746. [CrossRef]
  • [10] Thorp JA, Jones PG, Knox E, Clark RH. Does antenatal corticosteroid therapy affect birth weight and head circumference? Obstet Gynecol. 2002; 99(1): 101-108. [CrossRef]
  • [11] Brown CM, Garovic VD. Drug treatment of hypertension in pregnancy. Drugs. 2014; 74(3): 283-296. [CrossRef]
  • [12] Mammaro A, Carrara S, Cavaliere A, Ermito S, Dinatale A, Pappalardo EM, Militello M, Pedata R. Hypertensive disorders of pregnancy. J Prenat Med. 2009; 3(1): 1-5.
  • [13] Butalia S, Audibert F, Côté AM, Firoz T, Logan AG, Magee LA, Mundle W, Rey E, Rabi DM, Daskalopoulou SS, Nerenberg KA; Hypertension Canada. Hypertension Canada's 2018 Guidelines for the Management of Hypertension in Pregnancy. Can J Cardiol. 2018; 34(5): 526-531. [CrossRef]
  • [14] Hoeltzenbein M, Beck E, Fietz AK, Wernicke J, Zinke S, Kayser A, Padberg S, Weber-Schoendorfer C, Meister R, Schaefer C. Pregnancy outcome after first trimester use of methyldopa: A prospective cohort study. Hypertension. 2017; 70(1): 201-208. [CrossRef]
  • [15] Orbach H, Matok I, Gorodischer R, Sheiner E, Daniel S, Wiznitzer A, Koren G, Levy A. Hypertension and antihypertensive drugs in pregnancy and perinatal outcomes. Am J Obstet Gynecol. 2013; 208(4): 301.e1-6. [CrossRef]
  • [16] Harbison AF, Polly DM, Musselman ME. Antiinfective therapy for pregnant or lactating patients in the emergency department. Am J Health Syst Pharm. 2015; 72(3): 189-197. [CrossRef]
  • [17] Lamont HF, Blogg HJ, Lamont RF. Safety of antimicrobial treatment during pregnancy: A current review of resistance, immunomodulation and teratogenicity. Expert Opin Drug Saf. 2014; 13(12): 1569-1581. [CrossRef]
  • [18] Jepsen P, Skriver MV, Floyd A, Lipworth L, Schønheyder HC, Sørensen HT. A population-based study of maternal use of amoxicillin and pregnancy outcome in Denmark. Br J Clin Pharmacol. 2003; 55(2): 216-221. [CrossRef]
  • [19] Czeizel AE, Rockenbauer M, Olsen J. Use of antibiotics during pregnancy. Eur J Obstet Gynecol Reprod Biol. 1998; 81(1): 1-8. [CrossRef]
  • [20] Vidal AC, Murphy SK, Murtha AP, Schildkraut JM, Soubry A, Huang Z, Neelon SE, Fuemmeler B, Iversen E, Wang F, Kurtzberg J, Jirtle RL, Hoyo C. Associations between antibiotic exposure during pregnancy, birth weight and aberrant methylation at imprinted genes among offspring. Int J Obes (Lond). 2013; 37(7): 907- 913. [CrossRef]
  • [21] Mueller NT, Rifas-Shiman SL, Blaser MJ, Gillman MW, Hivert MF. Association of prenatal antibiotics with foetal size and cord blood leptin and adiponectin. Pediatr Obes. 2017; 12(2): 129-136. [CrossRef]

Yıl 2023, Cilt: 27 Sayı: Current Research Topıcs In Pharmacy: Pharmacology Debates, 10 - 14, 28.06.2025

Miloš N. Milosavljević , Jovana Milosavljević Ana V. Pejčić , Petar Arsenijević Ivana živanović Mačužić Nevena Folić Slobodan Janković

Öz

Kaynakça

  • [1] Kheirouri S, Alizadeh M. Impact of prenatal maternal factors and birth order on the anthropometric status of newborns in Iran. J Biosoc Sci. 2017; 49(2): 251-264. [CrossRef]
  • [2] Zeljkovic A, Vekic J, Spasic S, Jelic-Ivanovic Z, Spasojevic-Kalimanovska V, Gojkovic T, Ardalic D, Mandic-Markovic V, Cerovic N, Mikovic Z. Changes in LDL and HDL subclasses in normal pregnancy and associations with birth weight, birth length and head circumference. Matern Child Health J. 2013; 17(3): 556-565. [CrossRef]
  • [3] Lunde A, Melve KK, Gjessing HK, Skjaerven R, Irgens LM. Genetic and environmental influences on birth weight, birth length, head circumference, and gestational age by use of population-based parent-offspring data. Am J Epidemiol. 2007; 165(7): 734-741. [CrossRef]
  • [4] Parazzini F, Benedetto C, Bortolus R. Nifedipine versus expectant management in mild to moderate hypertension in pregnancy. Br J Obstet Gynaecol. 1998; 105(7): 718–722. [CrossRef]
  • [5] Karahanoglu E, Altinboga O, Akpinar F, Demirdag E, Ozdemirci S, Akyol A, Yalvac S. Nifedipine increases fetoplacental perfusion. J Perinat Med. 2017; 45(1): 51-55. [CrossRef]
  • [6] Milosavljević J, Pejčić A, Arsenijević P, Dimitrijević A, Milosavljević M, Mihajlović D, Janković S. Testing of new instrument for measuring quality and diversity of nutrition in pregnancy. Ginekol Pol. 2023; 94(1): 73-78. [CrossRef]
  • [7] Kemp MW, Newnham JP, Challis JG, Jobe AH, Stock SJ. The clinical use of corticosteroids in pregnancy. Hum Reprod Update. 2016; 22(2): 240-259. [CrossRef]
  • [8] Crowther CA, McKinlay CJ, Middleton P, Harding JE. Repeat doses of prenatal corticosteroids for women at risk of preterm birth for improving neonatal health outcomes. Cochrane Database Syst Rev. 2015; 2015(7): CD003935. [CrossRef]
  • [9] Rodriguez A, Wang Y, Ali Khan A, Cartwright R, Gissler M, Järvelin MR. Antenatal corticosteroid therapy (ACT) and size at birth: A population-based analysis using the Finnish Medical Birth Register. PLoS Med. 2019; 16(2): e1002746. [CrossRef]
  • [10] Thorp JA, Jones PG, Knox E, Clark RH. Does antenatal corticosteroid therapy affect birth weight and head circumference? Obstet Gynecol. 2002; 99(1): 101-108. [CrossRef]
  • [11] Brown CM, Garovic VD. Drug treatment of hypertension in pregnancy. Drugs. 2014; 74(3): 283-296. [CrossRef]
  • [12] Mammaro A, Carrara S, Cavaliere A, Ermito S, Dinatale A, Pappalardo EM, Militello M, Pedata R. Hypertensive disorders of pregnancy. J Prenat Med. 2009; 3(1): 1-5.
  • [13] Butalia S, Audibert F, Côté AM, Firoz T, Logan AG, Magee LA, Mundle W, Rey E, Rabi DM, Daskalopoulou SS, Nerenberg KA; Hypertension Canada. Hypertension Canada's 2018 Guidelines for the Management of Hypertension in Pregnancy. Can J Cardiol. 2018; 34(5): 526-531. [CrossRef]
  • [14] Hoeltzenbein M, Beck E, Fietz AK, Wernicke J, Zinke S, Kayser A, Padberg S, Weber-Schoendorfer C, Meister R, Schaefer C. Pregnancy outcome after first trimester use of methyldopa: A prospective cohort study. Hypertension. 2017; 70(1): 201-208. [CrossRef]
  • [15] Orbach H, Matok I, Gorodischer R, Sheiner E, Daniel S, Wiznitzer A, Koren G, Levy A. Hypertension and antihypertensive drugs in pregnancy and perinatal outcomes. Am J Obstet Gynecol. 2013; 208(4): 301.e1-6. [CrossRef]
  • [16] Harbison AF, Polly DM, Musselman ME. Antiinfective therapy for pregnant or lactating patients in the emergency department. Am J Health Syst Pharm. 2015; 72(3): 189-197. [CrossRef]
  • [17] Lamont HF, Blogg HJ, Lamont RF. Safety of antimicrobial treatment during pregnancy: A current review of resistance, immunomodulation and teratogenicity. Expert Opin Drug Saf. 2014; 13(12): 1569-1581. [CrossRef]
  • [18] Jepsen P, Skriver MV, Floyd A, Lipworth L, Schønheyder HC, Sørensen HT. A population-based study of maternal use of amoxicillin and pregnancy outcome in Denmark. Br J Clin Pharmacol. 2003; 55(2): 216-221. [CrossRef]
  • [19] Czeizel AE, Rockenbauer M, Olsen J. Use of antibiotics during pregnancy. Eur J Obstet Gynecol Reprod Biol. 1998; 81(1): 1-8. [CrossRef]
  • [20] Vidal AC, Murphy SK, Murtha AP, Schildkraut JM, Soubry A, Huang Z, Neelon SE, Fuemmeler B, Iversen E, Wang F, Kurtzberg J, Jirtle RL, Hoyo C. Associations between antibiotic exposure during pregnancy, birth weight and aberrant methylation at imprinted genes among offspring. Int J Obes (Lond). 2013; 37(7): 907- 913. [CrossRef]
  • [21] Mueller NT, Rifas-Shiman SL, Blaser MJ, Gillman MW, Hivert MF. Association of prenatal antibiotics with foetal size and cord blood leptin and adiponectin. Pediatr Obes. 2017; 12(2): 129-136. [CrossRef]
Toplam 21 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Eczacılık ve İlaç Bilimleri (Diğer)
Bölüm Articles
Yazarlar

Miloš N. Milosavljević 0000-0002-1786-1507

Jovana Milosavljević 0000-0001-9660-6709

Ana V. Pejčić 0000-0003-1741-0025

Petar Arsenijević 0000-0001-8267-7717

Ivana živanović Mačužić 0000-0001-6860-7237

Nevena Folić 0000-0001-9494-881X

Slobodan Janković 0000-0002-1519-8828

Yayımlanma Tarihi 28 Haziran 2025
Yayımlandığı Sayı Yıl 2023 Cilt: 27 Sayı: Current Research Topıcs In Pharmacy: Pharmacology Debates

Kaynak Göster

APA Milosavljević, M. N., Milosavljević, J., Pejčić, A. V., Arsenijević, P., vd. (2025). DRUGS AFFECTING NEWBORN WEIGHT, LENGTH AND HEAD CIRCUMFERENCE AT BIRTH. Journal of Research in Pharmacy, 27(Current Research Topıcs In Pharmacy: Pharmacology Debates), 10-14.
AMA Milosavljević MN, Milosavljević J, Pejčić AV, Arsenijević P, živanović Mačužić I, Folić N, Janković S. DRUGS AFFECTING NEWBORN WEIGHT, LENGTH AND HEAD CIRCUMFERENCE AT BIRTH. J. Res. Pharm. Temmuz 2025;27(Current Research Topıcs In Pharmacy: Pharmacology Debates):10-14.
Chicago Milosavljević, Miloš N., Jovana Milosavljević, Ana V. Pejčić, Petar Arsenijević, Ivana živanović Mačužić, Nevena Folić, ve Slobodan Janković. “DRUGS AFFECTING NEWBORN WEIGHT, LENGTH AND HEAD CIRCUMFERENCE AT BIRTH”. Journal of Research in Pharmacy 27, sy. Current Research Topıcs In Pharmacy: Pharmacology Debates (Temmuz 2025): 10-14.
EndNote Milosavljević MN, Milosavljević J, Pejčić AV, Arsenijević P, živanović Mačužić I, Folić N, Janković S (01 Temmuz 2025) DRUGS AFFECTING NEWBORN WEIGHT, LENGTH AND HEAD CIRCUMFERENCE AT BIRTH. Journal of Research in Pharmacy 27 Current Research Topıcs In Pharmacy: Pharmacology Debates 10–14.
IEEE M. N. Milosavljević, J. Milosavljević, A. V. Pejčić, P. Arsenijević, I. živanović Mačužić, N. Folić, ve S. Janković, “DRUGS AFFECTING NEWBORN WEIGHT, LENGTH AND HEAD CIRCUMFERENCE AT BIRTH”, J. Res. Pharm., c. 27, sy. Current Research Topıcs In Pharmacy: Pharmacology Debates, ss. 10–14, 2025.
ISNAD Milosavljević, Miloš N. vd. “DRUGS AFFECTING NEWBORN WEIGHT, LENGTH AND HEAD CIRCUMFERENCE AT BIRTH”. Journal of Research in Pharmacy 27/Current Research Topıcs In Pharmacy: Pharmacology Debates (Temmuz 2025), 10-14.
JAMA Milosavljević MN, Milosavljević J, Pejčić AV, Arsenijević P, živanović Mačužić I, Folić N, Janković S. DRUGS AFFECTING NEWBORN WEIGHT, LENGTH AND HEAD CIRCUMFERENCE AT BIRTH. J. Res. Pharm. 2025;27:10–14.
MLA Milosavljević, Miloš N. vd. “DRUGS AFFECTING NEWBORN WEIGHT, LENGTH AND HEAD CIRCUMFERENCE AT BIRTH”. Journal of Research in Pharmacy, c. 27, sy. Current Research Topıcs In Pharmacy: Pharmacology Debates, 2025, ss. 10-14.
Vancouver Milosavljević MN, Milosavljević J, Pejčić AV, Arsenijević P, živanović Mačužić I, Folić N, Janković S. DRUGS AFFECTING NEWBORN WEIGHT, LENGTH AND HEAD CIRCUMFERENCE AT BIRTH. J. Res. Pharm. 2025;27(Current Research Topıcs In Pharmacy: Pharmacology Debates):10-4.