Protective effects of Nigella sativa against hypertension-induced oxidative stress and cardiovascular dysfunction in rats
Öz
Anahtar Kelimeler
Antioxidant activity hypertension oxidative stress Nigella sativa
Kaynakça
- Textor SC, Lerman L. Renovascular hypertension and ischemic nephropathy.Am J Hypertens 2010; 23:1159-69.
- Laursen JB, Rajagopalan S, Galis Z, Tarpey M, Freeman BA, Harrison DG.. Role of superoxide in angiotensin-II- induced but not catecholamine-induced hypertension. Circulation 1997; 95:588–93.
- Griendling KK, Minieri CA, Ollerenshaw JD, Alexander RW. Angiotensin II stimulates NADH and NADPH oxi- dase activity in cultured vascular smooth muscle cells. Circ Res 1994; 74:1141-8.
- Minuz P, Patrignani P, Gaino S, Degan M, Menapace L, Tommasoli R, Seta F, Capone ML, Tacconelli S, Palatresi S, Bencini C, Del Vecchio C, Mansueto G, Arosio E, San- tonastaso CL, Lechi A, Morganti A, Patrono C. Increased oxidative stress and platelet activation in patients with hypertension and renovascular disease. Circulation 2002; 106:2800-5.
- Chong AY, Blann AD, Lip GY. Assessment of endothe- lial damage and dysfunction: observations in relation to heart failure. QJM 2003; 96:253-67.
- Chade AR, Rodriguez-Porcel M, Herrmann J, Zhu X, Grande JP, Napoli C, Lerman A, Lerman LO. Antioxi- dant intervention blunts renal injury in experimental renovascular disease. J Am Soc Nephrol 2004; 15: 958-66.
- Ali BH, Blunden G. Pharmacological and toxicological properties of Nigella sativa. Phytother Res 2003; 17:299-305.
- Badary OA, Taha RA, Gamal el-Din AM, Abdel-Wahab MH. Thymoquinone is a potent superoxide anion scav- enger. Drug Chem Toxicol 2003; 26:87-98.
- Erşahin M, Toklu HZ, Akakin D, Yuksel M, Yeğen BC, Sener G. The effects of Nigella sativa against oxidative in- jury in a rat model of subarachnoid hemorrhage. Acta Neurochir (Wien) 2011; 153: 333-41.
- Helle F Vågnes ØB, Iversen BM. Angiotensin II-induced calcium signaling in the afferent arteriole from rats with two-kidney, one-clip hypertension. Am J Physiol Renal Physiol 2006; 291: F140-7.
- Schiller NB Shah PM, Crawford M, DeMaria A, De- vereux R, Feigenbaum H, Gutgesell H, Reichek N, Sahn D, Schnittger I, et al. Recommendations for quantitation of the left ventricle by two-dimensional echocardiogra- phy. American Society of Echocardiography Committee on Standards, Subcommittee on Quantitation of Two- Dimensional Echocardiograms. J Am Soc Echocardiogr 1989; 2: 358-67.
- Haklar G, Ulukaya-Durakbaşa C, Yüksel M, Daglı T, Yalcin AS. Oxygen radicals and nitric oxide in rat me- senteric ischemia-reperfusion: modulation by L-arginine and N-nitro-L-arginine methyl ester. Clin Exp Pharma- col Physiol 1998; 25:908-12.
- Beuge JA, Aust SD. Microsomal lipid peroxidation. Meth Enzymol 1978; 52: 302-11.
- Beutler E. Glutathione in red blood cell metabolism. A Manuel of Biochemical Methods. New York, Grune & Stratton, 1975, pp.112-4.
- Reading HW, Isbir T. The role of cation-activated ATPas- es in transmitter release from the rat iris. Q J Exp Physiol Cogn Med Sci 1980; 65:105-16.
- Fiske CH, Subbarow Y. The colorimetric determination of phosphorus. J Biol Chem 1925; 66:375-400.
- Lowry OH RN, Farr AL, Randall RJ. Protein Measure- ments with the folin phenol reagent. J Biol Chem 1951; 193:265-75.
- Bai Y, Hui R. Dimethylarginine dimethylaminohy- drolase (DDAH)--a critical regulator of hypertensive left ventricular hypertrophy? Med Hypotheses 2008; 70:962-6.
- Leiper J, Nandi M, Torondel B, Murray-Rust J, Malaki M, O’Hara B, Rossiter S, Anthony S, Madhani M, Selwood D, Smith C, Wojciak-Stothard B, Rudiger A, Stidwill R, McDonald NQ, Vallance P. Disruption of methyl- arginine metabolism impairs vascular homeostasis. Nat Med 2007; 13:198-203.
- Rajagopalan S, Kurz S, Munzel T, Tarpey M, Freeman BA, Griendling KK, Harrison DG. Angiotensin II-medi- ated hypertension in the rat increases vascular superox- ide production via membrane NADH/NADPH oxidase activation: contribution to alterations of vasomotor tone. J Clin Invest 1996; 97:1916–23.
- Kako K, Kato M, Matsuoka T, Mustapha A. Depression of membrane-bound Na+-K+-ATPase activity induced by free radicals and by ischemia of kidney. Am J Physiol 1988; 254:C330-7.
- Ross, D. Glutathione, free radicals and chemotherapeutic agents. Mechanisms of free-radical induced toxicity and glutathione-dependent protection. Pharmacol Ther 1988; 37:231-49.
- Vaziri ND, Wang XQ, Oveisi F, Zhou XJ. Induction of oxidative stress by glutathione depletion causes se- vere hypertension in normal rats. Hypertension 2000; 36:142–6.
- Erşahin M, Sehirli O, Toklu HZ, Süleymanoglu S, Eme- kli-Alturfan E, Yarat A, Tatlidede E, Yeğen BC, Sener G. Melatonin improves cardiovascular function and amel- iorates renal, cardiac and cerebral damage in rats with renovascular hypertension. J Pineal Res 2009; 47:97-106.
- Mansour SM, Bahgat AK, El-Khatib AS, Khayyal MT. Ginkgo biloba extract (EGb 761) normalizes hypertension in 2K, 1C hypertensive rats: Role of antioxidant mecha- nisms, ACE inhibiting activity and improvement of en- dothelial dysfunction. Phytomedicine. 2011; 18:641-7.
- Abdelmeguid NE, Fakhoury R, Kamal SM, Al Wafai RJ. Effects of Nigella sativa and thymoquinone on biochemical and subcellular changes in pancreatic β-cells of streptozo- tocin-induced diabetic rats. J Diabetes 2010; 2:256-66.
- El-Abhar HS, Abdallah DM, Saleh S. Gastroprotective activity of Nigella sativa oil and its constituent, thymoqui- none, against gastric mucosal injury induced by ischae- mia/reperfusion in rats. J Ethnopharmacol 2003; 84:251-8.
- Badary OA, Abdel-Naim AB, Abdel-Wahab MH, Hama- da FM. The influence of thymoquinone on doxorubicin- induced hyperlipidemic nephropathy in rats. Toxicology 2000; 143:219-26.
- Khattab MM, Nagi MN. Thymoquinone supplementa- tion attenuates hypertension and renal damage in nitric oxide deficient hypertensive rats. Phytother Res 2007; 21:410–4.
- Ismail M, Al-Naqeep G, Chan KW. Nigella sativa thy- moquinone-rich fraction greatly improves plasma anti- oxidant capacity and expression of antioxidant genes in hypercholesterolemic rats. Free Radic Biol Med 2010; 48:664-72.
- Gradman AH, Alfayoumi F. From left ventricular hyper- trophy to congestive heart failure: management of hyper- tensive heart disease. Prog Cardiovasc Dis 2006; 48: 326–41.
Protective effects of Nigella sativa against hypertension-induced oxidative stress and cardiovascular dysfunction in rats
Öz
Kaynakça
- Textor SC, Lerman L. Renovascular hypertension and ischemic nephropathy.Am J Hypertens 2010; 23:1159-69.
- Laursen JB, Rajagopalan S, Galis Z, Tarpey M, Freeman BA, Harrison DG.. Role of superoxide in angiotensin-II- induced but not catecholamine-induced hypertension. Circulation 1997; 95:588–93.
- Griendling KK, Minieri CA, Ollerenshaw JD, Alexander RW. Angiotensin II stimulates NADH and NADPH oxi- dase activity in cultured vascular smooth muscle cells. Circ Res 1994; 74:1141-8.
- Minuz P, Patrignani P, Gaino S, Degan M, Menapace L, Tommasoli R, Seta F, Capone ML, Tacconelli S, Palatresi S, Bencini C, Del Vecchio C, Mansueto G, Arosio E, San- tonastaso CL, Lechi A, Morganti A, Patrono C. Increased oxidative stress and platelet activation in patients with hypertension and renovascular disease. Circulation 2002; 106:2800-5.
- Chong AY, Blann AD, Lip GY. Assessment of endothe- lial damage and dysfunction: observations in relation to heart failure. QJM 2003; 96:253-67.
- Chade AR, Rodriguez-Porcel M, Herrmann J, Zhu X, Grande JP, Napoli C, Lerman A, Lerman LO. Antioxi- dant intervention blunts renal injury in experimental renovascular disease. J Am Soc Nephrol 2004; 15: 958-66.
- Ali BH, Blunden G. Pharmacological and toxicological properties of Nigella sativa. Phytother Res 2003; 17:299-305.
- Badary OA, Taha RA, Gamal el-Din AM, Abdel-Wahab MH. Thymoquinone is a potent superoxide anion scav- enger. Drug Chem Toxicol 2003; 26:87-98.
- Erşahin M, Toklu HZ, Akakin D, Yuksel M, Yeğen BC, Sener G. The effects of Nigella sativa against oxidative in- jury in a rat model of subarachnoid hemorrhage. Acta Neurochir (Wien) 2011; 153: 333-41.
- Helle F Vågnes ØB, Iversen BM. Angiotensin II-induced calcium signaling in the afferent arteriole from rats with two-kidney, one-clip hypertension. Am J Physiol Renal Physiol 2006; 291: F140-7.
- Schiller NB Shah PM, Crawford M, DeMaria A, De- vereux R, Feigenbaum H, Gutgesell H, Reichek N, Sahn D, Schnittger I, et al. Recommendations for quantitation of the left ventricle by two-dimensional echocardiogra- phy. American Society of Echocardiography Committee on Standards, Subcommittee on Quantitation of Two- Dimensional Echocardiograms. J Am Soc Echocardiogr 1989; 2: 358-67.
- Haklar G, Ulukaya-Durakbaşa C, Yüksel M, Daglı T, Yalcin AS. Oxygen radicals and nitric oxide in rat me- senteric ischemia-reperfusion: modulation by L-arginine and N-nitro-L-arginine methyl ester. Clin Exp Pharma- col Physiol 1998; 25:908-12.
- Beuge JA, Aust SD. Microsomal lipid peroxidation. Meth Enzymol 1978; 52: 302-11.
- Beutler E. Glutathione in red blood cell metabolism. A Manuel of Biochemical Methods. New York, Grune & Stratton, 1975, pp.112-4.
- Reading HW, Isbir T. The role of cation-activated ATPas- es in transmitter release from the rat iris. Q J Exp Physiol Cogn Med Sci 1980; 65:105-16.
- Fiske CH, Subbarow Y. The colorimetric determination of phosphorus. J Biol Chem 1925; 66:375-400.
- Lowry OH RN, Farr AL, Randall RJ. Protein Measure- ments with the folin phenol reagent. J Biol Chem 1951; 193:265-75.
- Bai Y, Hui R. Dimethylarginine dimethylaminohy- drolase (DDAH)--a critical regulator of hypertensive left ventricular hypertrophy? Med Hypotheses 2008; 70:962-6.
- Leiper J, Nandi M, Torondel B, Murray-Rust J, Malaki M, O’Hara B, Rossiter S, Anthony S, Madhani M, Selwood D, Smith C, Wojciak-Stothard B, Rudiger A, Stidwill R, McDonald NQ, Vallance P. Disruption of methyl- arginine metabolism impairs vascular homeostasis. Nat Med 2007; 13:198-203.
- Rajagopalan S, Kurz S, Munzel T, Tarpey M, Freeman BA, Griendling KK, Harrison DG. Angiotensin II-medi- ated hypertension in the rat increases vascular superox- ide production via membrane NADH/NADPH oxidase activation: contribution to alterations of vasomotor tone. J Clin Invest 1996; 97:1916–23.
- Kako K, Kato M, Matsuoka T, Mustapha A. Depression of membrane-bound Na+-K+-ATPase activity induced by free radicals and by ischemia of kidney. Am J Physiol 1988; 254:C330-7.
- Ross, D. Glutathione, free radicals and chemotherapeutic agents. Mechanisms of free-radical induced toxicity and glutathione-dependent protection. Pharmacol Ther 1988; 37:231-49.
- Vaziri ND, Wang XQ, Oveisi F, Zhou XJ. Induction of oxidative stress by glutathione depletion causes se- vere hypertension in normal rats. Hypertension 2000; 36:142–6.
- Erşahin M, Sehirli O, Toklu HZ, Süleymanoglu S, Eme- kli-Alturfan E, Yarat A, Tatlidede E, Yeğen BC, Sener G. Melatonin improves cardiovascular function and amel- iorates renal, cardiac and cerebral damage in rats with renovascular hypertension. J Pineal Res 2009; 47:97-106.
- Mansour SM, Bahgat AK, El-Khatib AS, Khayyal MT. Ginkgo biloba extract (EGb 761) normalizes hypertension in 2K, 1C hypertensive rats: Role of antioxidant mecha- nisms, ACE inhibiting activity and improvement of en- dothelial dysfunction. Phytomedicine. 2011; 18:641-7.
- Abdelmeguid NE, Fakhoury R, Kamal SM, Al Wafai RJ. Effects of Nigella sativa and thymoquinone on biochemical and subcellular changes in pancreatic β-cells of streptozo- tocin-induced diabetic rats. J Diabetes 2010; 2:256-66.
- El-Abhar HS, Abdallah DM, Saleh S. Gastroprotective activity of Nigella sativa oil and its constituent, thymoqui- none, against gastric mucosal injury induced by ischae- mia/reperfusion in rats. J Ethnopharmacol 2003; 84:251-8.
- Badary OA, Abdel-Naim AB, Abdel-Wahab MH, Hama- da FM. The influence of thymoquinone on doxorubicin- induced hyperlipidemic nephropathy in rats. Toxicology 2000; 143:219-26.
- Khattab MM, Nagi MN. Thymoquinone supplementa- tion attenuates hypertension and renal damage in nitric oxide deficient hypertensive rats. Phytother Res 2007; 21:410–4.
- Ismail M, Al-Naqeep G, Chan KW. Nigella sativa thy- moquinone-rich fraction greatly improves plasma anti- oxidant capacity and expression of antioxidant genes in hypercholesterolemic rats. Free Radic Biol Med 2010; 48:664-72.
- Gradman AH, Alfayoumi F. From left ventricular hyper- trophy to congestive heart failure: management of hyper- tensive heart disease. Prog Cardiovasc Dis 2006; 48: 326–41.
Toplam 31 adet kaynakça vardır.
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Bölüm | Makaleler |
| Yazarlar | |
| Yayımlanma Tarihi | 7 Mart 2014 |
| Yayımlandığı Sayı | Yıl 2012 Cilt: 16 Sayı: 2 |
Kaynak Göster
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