Araştırma Makalesi
Yıl 2020,
Cilt: 21 Sayı: 2, 122 - 127, 31.08.2020
Öz
Kaynakça
- 1. D’aiuto F, Nibali L, Parkar M, Patel K, Suvan J, Donos N. Oxidative stress, systemic inflammation, and severe periodontitis. J Dent Res 2010; 89: 1241-6.
- 2. Salzberg TN, Overstreet BT, Rogers JD, Califano JV, Best AM, Schenkein HA. C-reactive protein levels in patients with aggressive periodontitis. J Periodontol 2006; 77: 933-9.
- 3. D’aiuto F, Nibali L, Parkar M, Suvan J, Tonetti M. Short-term effects of intensive periodontal therapy on serum inflammatory markers and cholesterol. J Dent Res 2005; 84: 269-73.
- 4. Ramirez-Tortosa M, Quiles J, Battino M, Granados S, Morillo JM, Bompadre S, et al. Periodontitis is associated with altered plasma fatty acids and cardiovascular risk markers. Nutr Metab Cardiovasc Dis 2010; 20: 133-9.
- 5. Ford PJ, Yamazaki K, Seymour GJ. Cardiovascular and oral disease interactions: what is the evidence? Prim Dent Care 2007; 14: 59-66.
- 6. Griffiths R, Barbour S. Lipoproteins and lipoprotein metabolism in periodontal disease. Clin Lipidol 2010; 5: 397-411.
- 7. Feingold KR, Grunfeld C. Effect of inflammation on HDL structure and function. Curr Opin Lipidol 2016; 27: 521-30.
- 8. Feingold KR, Grunfeld C. The effect of inflammation and infection on lipids and lipoproteins in Endotext. MDText. com, South Dartmouth, Mass, USA; 2015.
- 9. Rufail ML, Schenkein HA, Barbour SE, Tew JG, van Antwerpen R. Altered lipoprotein subclass distribution and PAF-AH activity in subjects with generalized aggressive periodontitis. J Lipid Res 2005; 46: 2752-60.
- 10. Kundi H, Kiziltunc E, Cetin M, Cicekcioglu H, Cetin ZG, Cicek G, et al. Association of monocyte/HDL-C ratio with SYNTAX scores in patients with stable coronary artery disease. Herz 2016; 41: 523-9.
- 11. Armitage GC. Development of a classification system for periodontal diseases and conditions. Ann Periodontol 1999; 4: 1-6.
- 12. Silness J, Loe H. Periodontal disease in pregnancy II. Correlation between oral hygiene and periodontal condition. Acta Odontol Scand 1964; 22: 121-35.
- 13. Tonetti M, Claffey N, European Workshop in Peridontology group C. Advances in the progression of periodontitis and proposal of definitions of a periodontitis case and disease progression for use in risk factor research: Group C Consensus report of the 5th European workshop in periodontology. J Clin Periodontol 2005; 32(Suppl 6): 210-3.
- 14. Löe H, Brown LJ. Early onset periodontitis in the United States of America. J Periodontol 1991; 62: 608-16.
- 15. Canpolat U. Monocyte-to-HDL-cholesterol ratio and left atrial remodelling in atrial fibrillation. Europace 2017; 19: 1409.
- 16. Kanbay M, Solak Y, Unal HU, Kurt YG, Gok M, Cetinkaya H, et al. Monocyte count/HDL cholesterol ratio and cardiovascular events in patients with chronic kidney disease. Int Urol Nephrol 2014; 46: 1619-25.
- 17. Kundi H, Gok M, Kiziltunc E, Cetin M, Cicekcioglu H, Cetin ZG, et al. Relation between monocyte to high-density lipoprotein cholesterol ratio with presence and severity of isolated coronary artery ectasia. Am J Cardiol 2015; 116: 1685-9.
- 18. Canpolat U, Aytemir K, Yorgun H, Şahiner L, Kaya EB, Çay S, et al. The role of preprocedural monocyte-to-high-density lipoprotein ratio in prediction of atrial fibrillation recurrence after cryoballoon-based catheter ablation. Europace 2015; 17: 1807-15.
- 19. Nibali L, D’aiuto F, Griffiths G, Patel K, Suvan J, Tonetti MS. Severe periodontitis is associated with systemic inflammation and a dysmetabolic status: a case-control study. J Clin Periodontol 2007; 34: 931-7.
- 20. Gao H, Tian Y, Meng H, Hou J, Xu L, Zhang L, et al. Associations of apolipoprotein E and low‐density lipoprotein receptor‐related protein 5 polymorphisms with dyslipidemia and generalized aggressive periodontitis in a Chinese population. J Periodontal Res 2015; 50: 509-18.
- 21. Davies R, Jaedicke K, Barksby H, Jitprasertwong P, Al-Shahwani RM, Taylor JJ, et al. Do patients with aggressive periodontitis have evidence of diabetes? A pilot study. J Periodontal Res 2011; 46: 663-72.
- 22. Andrukhov O, Haririan H, Bertl K, Rausch WD, Bantleon HP, Moritz A, et al. Nitric oxide production, systemic inflammation and lipid metabolism in periodontitis patients: possible gender aspect. J Clin Periodontol 2013; 40: 916-23.
- 23. Kırzıoğlu FY, Fentoğlu Ö, Bulut MT, Doğan B, Özdem M, Özmen Ö, et al. Is a Cholestrol‐Enriched Diet a Risk Factor for Alveolar Bone Loss? J Periodontol 2016; 87: 529-38.
- 24. Fentoglu O, Kale Köroglu B, Kara Y, Doğan B, Yılmaz G, Sütçü R, et al. Serum lipoprotein-associated phospholipase A2 and C-reactive protein levels in association with periodontal disease and hyperlipidemia. J Periodontol 2011; 82: 350-9.
- 25. Schaefer AS, Richter GM, Groessner-Schreiber B, Noack B, Nothnagel M, El Mokhtari NE, et al. Identification of a shared genetic susceptibility locus for coronary heart disease and periodontitis. PLoS Genet 2009; 5: e1000378.
The Relationship Between Monocyte Count to High-density Lipoprotein Ratio and Severity of Inflammation in Aggressive Periodontitis: A Retrospective Analysis
Öz
Objective: Hyperlipidemia is a known cardiovascular disease risk factor. A common biological mechanism between systemic diseases, such as cardiovascular diseases, and periodontal diseases has been suggested. This study aimed to examine the association between blood lipid profile and the severity of aggressive periodontitis (AgP).
Materials and Methods: A total of 32 systemically healthy patients with AgP (24 females and 8 males; mean age 34.78±6.42 years) were consecutively selected. The patients were divided into 2 groups as localised AgP (LAgP) and generalised AgP (GAgP). Monocyte counts, high-density level (HDL) count and monocyte/HDL ratios (MHR) were recorded from the patients’ blood samples. Mean Plaque index, bleeding on probing, periodontal pocket depth and clinical attachment level were recorded before treatment. The relationship between monocyte to HDL ratios and clinical attachment level between the groups were analysed by Spearman correlation.
Results: Sixteen GAgP and 16 LagP patients were included in the study. The mean MHR values for the LAgP and GAgP groups were 9.87±2.85 and 13.43±4.64, respectively; there was a statistically significant difference between the groups (p<0.05).
Conclusion: The increased MHR values in patients with severe periodontitis may be one of the pathogenic mechanisms underlying the link between periodontal and cardiovascular diseases. Although we observed statistically significant differences between the MHR values in both groups, a larger sample size is needed to confirm the results of this study in the future.
Anahtar Kelimeler
Aggressive periodontitis monocytes highdensity lipoproteins diagnosis
Kaynakça
- 1. D’aiuto F, Nibali L, Parkar M, Patel K, Suvan J, Donos N. Oxidative stress, systemic inflammation, and severe periodontitis. J Dent Res 2010; 89: 1241-6.
- 2. Salzberg TN, Overstreet BT, Rogers JD, Califano JV, Best AM, Schenkein HA. C-reactive protein levels in patients with aggressive periodontitis. J Periodontol 2006; 77: 933-9.
- 3. D’aiuto F, Nibali L, Parkar M, Suvan J, Tonetti M. Short-term effects of intensive periodontal therapy on serum inflammatory markers and cholesterol. J Dent Res 2005; 84: 269-73.
- 4. Ramirez-Tortosa M, Quiles J, Battino M, Granados S, Morillo JM, Bompadre S, et al. Periodontitis is associated with altered plasma fatty acids and cardiovascular risk markers. Nutr Metab Cardiovasc Dis 2010; 20: 133-9.
- 5. Ford PJ, Yamazaki K, Seymour GJ. Cardiovascular and oral disease interactions: what is the evidence? Prim Dent Care 2007; 14: 59-66.
- 6. Griffiths R, Barbour S. Lipoproteins and lipoprotein metabolism in periodontal disease. Clin Lipidol 2010; 5: 397-411.
- 7. Feingold KR, Grunfeld C. Effect of inflammation on HDL structure and function. Curr Opin Lipidol 2016; 27: 521-30.
- 8. Feingold KR, Grunfeld C. The effect of inflammation and infection on lipids and lipoproteins in Endotext. MDText. com, South Dartmouth, Mass, USA; 2015.
- 9. Rufail ML, Schenkein HA, Barbour SE, Tew JG, van Antwerpen R. Altered lipoprotein subclass distribution and PAF-AH activity in subjects with generalized aggressive periodontitis. J Lipid Res 2005; 46: 2752-60.
- 10. Kundi H, Kiziltunc E, Cetin M, Cicekcioglu H, Cetin ZG, Cicek G, et al. Association of monocyte/HDL-C ratio with SYNTAX scores in patients with stable coronary artery disease. Herz 2016; 41: 523-9.
- 11. Armitage GC. Development of a classification system for periodontal diseases and conditions. Ann Periodontol 1999; 4: 1-6.
- 12. Silness J, Loe H. Periodontal disease in pregnancy II. Correlation between oral hygiene and periodontal condition. Acta Odontol Scand 1964; 22: 121-35.
- 13. Tonetti M, Claffey N, European Workshop in Peridontology group C. Advances in the progression of periodontitis and proposal of definitions of a periodontitis case and disease progression for use in risk factor research: Group C Consensus report of the 5th European workshop in periodontology. J Clin Periodontol 2005; 32(Suppl 6): 210-3.
- 14. Löe H, Brown LJ. Early onset periodontitis in the United States of America. J Periodontol 1991; 62: 608-16.
- 15. Canpolat U. Monocyte-to-HDL-cholesterol ratio and left atrial remodelling in atrial fibrillation. Europace 2017; 19: 1409.
- 16. Kanbay M, Solak Y, Unal HU, Kurt YG, Gok M, Cetinkaya H, et al. Monocyte count/HDL cholesterol ratio and cardiovascular events in patients with chronic kidney disease. Int Urol Nephrol 2014; 46: 1619-25.
- 17. Kundi H, Gok M, Kiziltunc E, Cetin M, Cicekcioglu H, Cetin ZG, et al. Relation between monocyte to high-density lipoprotein cholesterol ratio with presence and severity of isolated coronary artery ectasia. Am J Cardiol 2015; 116: 1685-9.
- 18. Canpolat U, Aytemir K, Yorgun H, Şahiner L, Kaya EB, Çay S, et al. The role of preprocedural monocyte-to-high-density lipoprotein ratio in prediction of atrial fibrillation recurrence after cryoballoon-based catheter ablation. Europace 2015; 17: 1807-15.
- 19. Nibali L, D’aiuto F, Griffiths G, Patel K, Suvan J, Tonetti MS. Severe periodontitis is associated with systemic inflammation and a dysmetabolic status: a case-control study. J Clin Periodontol 2007; 34: 931-7.
- 20. Gao H, Tian Y, Meng H, Hou J, Xu L, Zhang L, et al. Associations of apolipoprotein E and low‐density lipoprotein receptor‐related protein 5 polymorphisms with dyslipidemia and generalized aggressive periodontitis in a Chinese population. J Periodontal Res 2015; 50: 509-18.
- 21. Davies R, Jaedicke K, Barksby H, Jitprasertwong P, Al-Shahwani RM, Taylor JJ, et al. Do patients with aggressive periodontitis have evidence of diabetes? A pilot study. J Periodontal Res 2011; 46: 663-72.
- 22. Andrukhov O, Haririan H, Bertl K, Rausch WD, Bantleon HP, Moritz A, et al. Nitric oxide production, systemic inflammation and lipid metabolism in periodontitis patients: possible gender aspect. J Clin Periodontol 2013; 40: 916-23.
- 23. Kırzıoğlu FY, Fentoğlu Ö, Bulut MT, Doğan B, Özdem M, Özmen Ö, et al. Is a Cholestrol‐Enriched Diet a Risk Factor for Alveolar Bone Loss? J Periodontol 2016; 87: 529-38.
- 24. Fentoglu O, Kale Köroglu B, Kara Y, Doğan B, Yılmaz G, Sütçü R, et al. Serum lipoprotein-associated phospholipase A2 and C-reactive protein levels in association with periodontal disease and hyperlipidemia. J Periodontol 2011; 82: 350-9.
- 25. Schaefer AS, Richter GM, Groessner-Schreiber B, Noack B, Nothnagel M, El Mokhtari NE, et al. Identification of a shared genetic susceptibility locus for coronary heart disease and periodontitis. PLoS Genet 2009; 5: e1000378.
Toplam 25 adet kaynakça vardır.
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Konular | Diş Hekimliği (Diğer) |
| Bölüm | Araştırma Makalesi |
| Yazarlar | |
| Yayımlanma Tarihi | 31 Ağustos 2020 |
| Yayımlandığı Sayı | Yıl 2020 Cilt: 21 Sayı: 2 |