Araştırma Makalesi
Yıl 2020,
Cilt: 21 Sayı: 3, 244 - 250, 31.12.2020
Öz
Objective: The purpose of this study was to determine whether fontanelle closure in neonatal and early infantry periods was related to vitamin D levels and the prophylaxis of vitamin D intake. Moreover, our analysis was structured in a retrospective, controlled manner to evaluate our hypothesis.
Materials and Methods: We considered 50 individuals who applied to our child endocrinology polyclinic with infants suffering from premature anterior closure. Further, 35 healthy infants of the same age and gender having open anterior fontanelles were taken as the control group.
Results: The serum vitamin D level was found to be lower, and the parathormone level was significantly higher in the group with premature closure of the anterior fontanelle. In addition, there was a significant difference in serum calcium, alkaline phosphatase and parathormone levels in patients who had ceased vitamin D support compared with regular vitamin D users. While there was no significant difference in serum vitamin D levels, the level was lower in patients who had withdrawn vitamin D support.
Conclusion: In our study, many infants have much lower vitamin D levels than normal levels, even though their anterior fontanelle is prematurely closed. Thus, physicians and other health workers are also warned of the continuity of vitamin D prophylaxis and that it is wrong to cease vitamin D support for reasons such as the premature closing of the anterior fontanelle.
Anahtar Kelimeler
Kaynakça
- 1. Holick MF. The vitamin D deficiency pandemic: Approaches for diagnosis, treatment and prevention. Rev Endocr Metab Disord 2017; 18: 153-65.
- 2. Christakos S, Dhawan P, Liu Y, Peng X, Porta A. New insights into the mechanisms of vitamin D action. J Cell Biochem 2003; 88: 695-705.
- 3. Plotkin H, Lifshitz F. Rickets and Osteoporosis. In: Liftshitz F, editor. Pediatric Endocrinology. 5th ed. New York: Informa Healthcare; 2007: 531-4.
- 4. Unuvar T, Büyükgebiz A. Nutritional rickets and vitamin D deficiency in infants, children and adolescents. Pediatr Endocrinol Rev 2010; 3: 283-91.
- 5. Gordon CM, De Peter KC, Feldman HA, Grace E, Emans SJ. Prevalence of vitamin D deficiency among healthy adolescents. Arch Pediatr Adolesc Med 2004; 158: 531-7.
- 6. Abrams SA, Griffin IJ, Hawthorne KM, Gunn SK, Gundberg CM, Carpenter TO. Relationships among vitamin D levels, parathyroid hormone, and calcium absorption in young adolescents. J Clin Endocrinol Metab 2005; 90: 5576-81.
- 7. Holick MF, Binkley NC, Bischoff-Ferrari HA, Gordon CM, Hanley DA, Heaney RP, et al. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 2011; 96: 1911-30.
- 8. Misra M, Pacaud D, Petryk A, Collett-Solberg PF, Kappy M. Vitamin D deficiency in children and its management: review of current knowledge and recommendations. Pediatrics 2008; 122: 398-417.
- 9. Holick MF. Vitamin D deficiency. N Engl J Med 2007; 357: 266-81.
- 10. Popich GA, Smith DW. Fontanelles: range of normal size. J Pediatr 1972; 80: 749-52.
- 11. Kliegman RM. The newborn infant. In: Behrman RE, Kliegman RM, Arvin AM, Nelson WE, editors. Nelson Textbook of pediatrics. 15th ed. Philadelphia: Saunders; 1996: 433-40.
- 12. Duc G, Largo RH. Anterior fontanelle: size and closure in term and preterm infants. Pediatrics 1986; 78: 904-8.
- 13. Wang J, Li H, He Q, Ren C. Effects of calcium and vitamin D supplementation on bone specific alkaline during pregnancy lactation and infant. Wei Sheng Yan Jiu 2009; 38: 193-5.
- 14. Gartner LM, Greer FR. Prevention of rickets and vitamin D deficiency: new guidelines for vitamin D intake. Pediatrics 2003; 111: 908-10.
- 15. Wagner CL, Greer FR. Prevention of rickets and vitamin D deficiency in infants, children, and adolescents. Pediatrics 2008; 122: 1142-52.
- 16. Hollis BW. Circulating 25-hydroxyvitamin D levels indicative of vitamin D sufficiency: implications for establishing a new effective dietary intake recommendation for vitamin D. J Nutr 2005; 135: 317-22.
- 17. Hatun Ş, İslam Ö, Cizmecioğlu F, Kara B, Babaoglu K. Subclinical Vitamin D Deficiency Is Increased in Adolescent Girls Who Wear Concealing Clothing. J Nutr 2005; 135: 218-22.
- 18. Zeghoud F, Vervel C, Guillozo H, Walrant-Debray O, Boutignon H, Garabédian M. Subclinical vitamin D deficiency in neonates: definition and response to vitamin D supplements. Am J Clin Nutr 1997; 65: 771-8.
- 19. Abdul-Razzak KK, Ajlony MJ, Khoursheed AM, Obeidat BA. Vitamin D deficiency among healthy infants and toddlers: A prospective study from Irbid, Jordan. Pediatr Int 2011; 53: 839-45.
- 20. Kalra P, Das V, Agarwal A, Kumar M, Ramesh V, Bhatia E, et al. Effect of vitamin D supplementation during pregnancy on neonatal mineral homeostasis and anthropometry of the newborn and infant. Br J Nutr 2012; 3: 1-7.
Yıl 2020,
Cilt: 21 Sayı: 3, 244 - 250, 31.12.2020
Öz
Kaynakça
- 1. Holick MF. The vitamin D deficiency pandemic: Approaches for diagnosis, treatment and prevention. Rev Endocr Metab Disord 2017; 18: 153-65.
- 2. Christakos S, Dhawan P, Liu Y, Peng X, Porta A. New insights into the mechanisms of vitamin D action. J Cell Biochem 2003; 88: 695-705.
- 3. Plotkin H, Lifshitz F. Rickets and Osteoporosis. In: Liftshitz F, editor. Pediatric Endocrinology. 5th ed. New York: Informa Healthcare; 2007: 531-4.
- 4. Unuvar T, Büyükgebiz A. Nutritional rickets and vitamin D deficiency in infants, children and adolescents. Pediatr Endocrinol Rev 2010; 3: 283-91.
- 5. Gordon CM, De Peter KC, Feldman HA, Grace E, Emans SJ. Prevalence of vitamin D deficiency among healthy adolescents. Arch Pediatr Adolesc Med 2004; 158: 531-7.
- 6. Abrams SA, Griffin IJ, Hawthorne KM, Gunn SK, Gundberg CM, Carpenter TO. Relationships among vitamin D levels, parathyroid hormone, and calcium absorption in young adolescents. J Clin Endocrinol Metab 2005; 90: 5576-81.
- 7. Holick MF, Binkley NC, Bischoff-Ferrari HA, Gordon CM, Hanley DA, Heaney RP, et al. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 2011; 96: 1911-30.
- 8. Misra M, Pacaud D, Petryk A, Collett-Solberg PF, Kappy M. Vitamin D deficiency in children and its management: review of current knowledge and recommendations. Pediatrics 2008; 122: 398-417.
- 9. Holick MF. Vitamin D deficiency. N Engl J Med 2007; 357: 266-81.
- 10. Popich GA, Smith DW. Fontanelles: range of normal size. J Pediatr 1972; 80: 749-52.
- 11. Kliegman RM. The newborn infant. In: Behrman RE, Kliegman RM, Arvin AM, Nelson WE, editors. Nelson Textbook of pediatrics. 15th ed. Philadelphia: Saunders; 1996: 433-40.
- 12. Duc G, Largo RH. Anterior fontanelle: size and closure in term and preterm infants. Pediatrics 1986; 78: 904-8.
- 13. Wang J, Li H, He Q, Ren C. Effects of calcium and vitamin D supplementation on bone specific alkaline during pregnancy lactation and infant. Wei Sheng Yan Jiu 2009; 38: 193-5.
- 14. Gartner LM, Greer FR. Prevention of rickets and vitamin D deficiency: new guidelines for vitamin D intake. Pediatrics 2003; 111: 908-10.
- 15. Wagner CL, Greer FR. Prevention of rickets and vitamin D deficiency in infants, children, and adolescents. Pediatrics 2008; 122: 1142-52.
- 16. Hollis BW. Circulating 25-hydroxyvitamin D levels indicative of vitamin D sufficiency: implications for establishing a new effective dietary intake recommendation for vitamin D. J Nutr 2005; 135: 317-22.
- 17. Hatun Ş, İslam Ö, Cizmecioğlu F, Kara B, Babaoglu K. Subclinical Vitamin D Deficiency Is Increased in Adolescent Girls Who Wear Concealing Clothing. J Nutr 2005; 135: 218-22.
- 18. Zeghoud F, Vervel C, Guillozo H, Walrant-Debray O, Boutignon H, Garabédian M. Subclinical vitamin D deficiency in neonates: definition and response to vitamin D supplements. Am J Clin Nutr 1997; 65: 771-8.
- 19. Abdul-Razzak KK, Ajlony MJ, Khoursheed AM, Obeidat BA. Vitamin D deficiency among healthy infants and toddlers: A prospective study from Irbid, Jordan. Pediatr Int 2011; 53: 839-45.
- 20. Kalra P, Das V, Agarwal A, Kumar M, Ramesh V, Bhatia E, et al. Effect of vitamin D supplementation during pregnancy on neonatal mineral homeostasis and anthropometry of the newborn and infant. Br J Nutr 2012; 3: 1-7.
Toplam 20 adet kaynakça vardır.
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Konular | Endokrinoloji |
| Bölüm | Araştırma Makalesi |
| Yazarlar | |
| Yayımlanma Tarihi | 31 Aralık 2020 |
| Yayımlandığı Sayı | Yıl 2020 Cilt: 21 Sayı: 3 |