Vitamin D Level and Infertility

Özgür Deniz Turan

doi:10.4274/meandros.2399

Derleme

Vitamin D Level and Infertility

Yıl 2018, Cilt: 19 Sayı: 2, 106 - 110, 31.08.2018

Özgür Deniz Turan

Öz

Infertility is one of the major health problems of our time. In fact, infertility is caused by many factors. Among these factors the effect of vitamin D levels of infertility are overlooked. The prevalence of vitamin D deficiency varies between 20% and 66.8% in different countries. In fact, vitamin D deficiency can lead to infertility both women and man. Lack of vitamin D in women with polycystic ovary syndrome in the study, uterine fibroids, as well as has been demonstrated over a relationship with a decrease in reserves. In males it has been suggested to affect sperm count and morphology. At the same time vitamin D levels may play a role in facilitating implantation. Even in studies in vitro fertilization has been shown to increase the success rate with the support of vitamin D. In this article, vitamin D deficiency and infertility issues were revised in light of the current articles.

Anahtar Kelimeler

Vitamin D, infertility, in vitro fertilization

Kaynakça

1. Holick MF. MrOs is D-ficient. J Clin Endocrinol Metab 2009; 94: 1092-3.
2. Bhan A, Rao AD, Rao DS. Osteomalacia as a result of vitamin D deficiency. Rheum Dis Clin North Am 2012; 38: 81-91.
3. Ramser JR, Frost HM, Frame B, Arnstein AR, Smith R. Tetracycline-based studies of bone dynamics in rib of 6 cases of osteomalacia. Clin Orthop Relat Res 1966; 46: 219-36.
4. Maghbooli Z, Hossein-Nezhad A, Shafaei AR, Karimi F, Madani FS, Larijani B. Vitamin D status in mothers and their newborns in Iran. BMC Pregnancy Childbirth 2007; 7: 1.
5. Weiler HA, Leslie WD, Krahn J, Steiman PW, Metge CJ. Canadian Aboriginal women have a higher prevalence of vitamin D deficiency than non-Aboriginal women despite similar dietary vitamin D intakes. J Nutr 2007; 137: 461-5.
6. Nanri A, Foo LH, Nakamura K, Hori A, Poudel-Tandukar K, Matsushita Y, et al. Serum 25-hydroxyvitamin d concentrations and season-specific correlates in Japanese adults. J Epidemiol 2011; 21: 346-53.
7. Hekimsoy Z, Dinç G, Kafesçiler S, Onur E, Güvenç Y, Pala T, et al. Vitamin D status among adults in the Aegean region of Turkey. BMC Public Health 2010; 10: 782.
8. Staud R. Vitamin D: more than just affecting calcium and bone. Curr Rheumatol Rep 2005; 7: 356-64.
9. Boucher BJ. The problems of vitamin d insufficiency in older people. Aging Dis 2012; 3: 313-29.
10. Autier P, Gandini S. Vitamin D supplementation and total mortality: a meta-analysis of randomized controlled trials. Arch Intern Med 2007; 167: 1730-7.
11. Mathieu C, van Etten E, Decallonne B, Guilietti A, Gysemans C, Bouillon R, et al. Vitamin D and 1,25-dihydroxyvitamin D3 as modulators in the immune system. J Steroid Biochem Mol Biol 2004; 89-90: 449-52.
12. Holick MF. The role of vitamin D for bone health and fracture prevention. Curr Osteoporos Rep 2006; 4: 96-102.
13. Laaksi I. Vitamin D and respiratory infection in adults. Proc Nutr Soc 2012; 71: 90-7.
14. Holick MF, Chen TC. Vitamin D deficiency: a worldwide problem with health consequences. Am J Clin Nutr 2008; 87: 1080-6.
15. Borges MC, Martini LA, Rogero MM. Current perspectives on vitamin D, immune system, and chronic diseases. Nutrition 2011; 27: 399-404.
16. Kulie T, Groff A, Redmer J, Hounshell J, Schrager S. Vitamin D: an evidence-based review. J Am Board Fam Med 2009; 22: 698-706.
17. Bordelon P, Ghetu MV, Langan RC. Recognition and management of vitamin D deficiency. Am Fam Physician 2009; 80: 841-6.
18. Azziz R, Woods KS, Reyna R, Key TJ, Knochenhauer ES, Yildiz BO. The prevalence and features of the polycystic ovary syndrome in an unselected population. J Clin Endocrinol Metab 2004; 89: 2745-9.
19. Ott J, Wattar L, Kurz C, Seemann R, Huber JC, Mayerhofer K, et al. Parameters for calcium metabolism in women with polycystic ovary syndrome who undergo clomiphene citrate stimulation: a prospective cohort study. Eur J Endocrinol 2012; 166: 897-902.
20. Rashidi B, Haghollahi F, Shariat M, Zayerii F. The effects of calcium-vitamin D and metformin on polycystic ovary syndrome: a pilot study. Taiwan J Obstet Gynecol 2009; 48: 142-7.
21. Irani M, Merhi Z. Role of vitamin D in ovarian physiology and its implication in reproduction: a systematic review. Fertil Steril 2014; 102: 460-8.
22. Reyman M, Verrijn Stuart AA, van Summeren M, Rakhshandehroo M, Nuboer R, de Boer FK, et al. Vitamin D deficiency in childhood obesity is associated with high levels of circulating inflammatory mediators, and low insulin sensitivity. Int J Obes (Lond) 2014; 38: 46-52.
23. Thomson RL, Spedding S, Brinkworth GD, Noakes M, Buckley JD. Seasonal effects on vitamin D status influence outcomes of lifestyle intervention in overweight and obese women with polycystic ovary syndrome. Fertil Steril 2013; 99: 1779-85.
24. Belenchia AM, Tosh AK, Hillman LS, Peterson CA. Correcting vitamin D insufficiency improves insulin sensitivity in obese adolescents: a randomized controlled trial. Am J Clin Nutr 2013; 97: 774-81.
25. Moini A, Shirzad N, Ahmadzadeh M, Hosseini R, Hosseini L, Sadatmahalleh SJ. Comparison of 25-hydroxyvitamin D and Calcium Levels between Polycystic Ovarian Syndrome and Normal Women. Int J Fertil Steril 2015; 9: 1-8.
26. Grundmann M, von Versen-Höynck F. Vitamin D - roles in women's reproductive health? Reprod Biol Endocrinol 2011; 9: 146.
27. Merhi ZO, Seifer DB, Weedon J, Adeyemi O, Holman S, Anastos K, et al. Circulating vitamin D correlates with serum antimüllerian hormone levels in late-reproductive-aged women: Women's Interagency HIV Study. Fertil Steril 2012; 98: 228-34.
28. Thibeault D, Caron N, Djiana R, Kremer R, Blank D. Development and optimization of simplified LC-MS/MS quantification of 25-hydroxyvitamin D using protein precipitation combined with on-line solid phase extraction (SPE). J Chromatogr B Analyt Technol Biomed Life Sci 2012; 883-884: 120-7.
29. Paffoni A, Somigliana E, Vigano' P, Benaglia L, Cardellicchio L, Pagliardini L, et al. Vitamin D status in women with uterine leiomyomas. J Clin Endocrinol Metab 2013; 98: E1374-8.
30. Halder SK, Osteen KG, Al-Hendy A. Vitamin D3 inhibits expression and activities of matrix metalloproteinase-2 and -9 in human uterine fibroid cells. Hum Reprod 2013; 28: 2407-16.
31. Rudick BJ, Ingles SA, Chung K, Stanczyk FZ, Paulson RJ, Bendikson KA. Influence of vitamin D levels on in vitro fertilization outcomes in donor-recipient cycles. Fertil Steril 2014; 101: 447-52.
32. Ozkan S, Jindal S, Greenseid K, Shu J, Zeitlian G, Hickmon C, et al. Replete vitamin D stores predict reproductive success following in vitro fertilization. Fertil Steril 2010; 94: 1314-9.
33. Anifandis GM, Dafopoulos K, Messini CI, Chalvatzas N, Liakos N, Pournaras S, et al. Prognostic value of follicular fluid 25-OH vitamin D and glucose levels in the IVF outcome. Reprod Biol Endocrinol 2010; 8: 91.
34. Franasiak JM, Molinaro TA, Dubell EK, Scott KL, Ruiz AR, Forman EJ, et al. Vitamin D levels do not affect IVF outcomes following the transfer of euploid blastocysts. Am J Obstet Gynecol 2015; 212: 315.e1-6.
35. Blomberg Jensen M, Bjerrum PJ, Jessen TE, Nielsen JE, Joensen UN, Olesen IA, et al. Vitamin D is positively associated with sperm motility and increases intracellular calcium in human spermatozoa. Hum Reprod 2011; 26: 1307-17.
36. Ramlau-Hansen CH, Moeller UK, Bonde JP, Olsen J, Thulstrup AM. Are serum levels of vitamin D associated with semen quality? Results from a cross-sectional study in young healthy men. Fertil Steril 2011; 95: 1000-4.
37. Lee DM, Tajar A, Pye SR, Boonen S, Vanderschueren D, Bouillon R, et al. Association of hypogonadism with vitamin D status: the European Male Ageing Study. Eur J Endocrinol 2012; 166: 77-85.
38. Nimptsch K, Platz EA, Willett WC, Giovannucci E. Association between plasma 25-OH vitamin D and testosterone levels in men. Clin Endocrinol (Oxf) 2012; 77: 106-12.
39. Foresta C, Selice R, Di Mambro A, Strapazzon G. Testiculopathy and vitamin D insufficiency. Lancet 2010; 376: 1301.
40. Blomberg Jensen M, Jørgensen A, Nielsen JE, Bjerrum PJ, Skalkam M, Petersen JH, et al. Expression of the vitamin D metabolizing enzyme CYP24A1 at the annulus of human spermatozoa may serve as a novel marker of semen quality. Int J Androl 2012; 35: 499-510.

Yıl 2018, Cilt: 19 Sayı: 2, 106 - 110, 31.08.2018

Özgür Deniz Turan

Öz

Kaynakça

1. Holick MF. MrOs is D-ficient. J Clin Endocrinol Metab 2009; 94: 1092-3.
2. Bhan A, Rao AD, Rao DS. Osteomalacia as a result of vitamin D deficiency. Rheum Dis Clin North Am 2012; 38: 81-91.
3. Ramser JR, Frost HM, Frame B, Arnstein AR, Smith R. Tetracycline-based studies of bone dynamics in rib of 6 cases of osteomalacia. Clin Orthop Relat Res 1966; 46: 219-36.
4. Maghbooli Z, Hossein-Nezhad A, Shafaei AR, Karimi F, Madani FS, Larijani B. Vitamin D status in mothers and their newborns in Iran. BMC Pregnancy Childbirth 2007; 7: 1.
5. Weiler HA, Leslie WD, Krahn J, Steiman PW, Metge CJ. Canadian Aboriginal women have a higher prevalence of vitamin D deficiency than non-Aboriginal women despite similar dietary vitamin D intakes. J Nutr 2007; 137: 461-5.
6. Nanri A, Foo LH, Nakamura K, Hori A, Poudel-Tandukar K, Matsushita Y, et al. Serum 25-hydroxyvitamin d concentrations and season-specific correlates in Japanese adults. J Epidemiol 2011; 21: 346-53.
7. Hekimsoy Z, Dinç G, Kafesçiler S, Onur E, Güvenç Y, Pala T, et al. Vitamin D status among adults in the Aegean region of Turkey. BMC Public Health 2010; 10: 782.
8. Staud R. Vitamin D: more than just affecting calcium and bone. Curr Rheumatol Rep 2005; 7: 356-64.
9. Boucher BJ. The problems of vitamin d insufficiency in older people. Aging Dis 2012; 3: 313-29.
10. Autier P, Gandini S. Vitamin D supplementation and total mortality: a meta-analysis of randomized controlled trials. Arch Intern Med 2007; 167: 1730-7.
11. Mathieu C, van Etten E, Decallonne B, Guilietti A, Gysemans C, Bouillon R, et al. Vitamin D and 1,25-dihydroxyvitamin D3 as modulators in the immune system. J Steroid Biochem Mol Biol 2004; 89-90: 449-52.
12. Holick MF. The role of vitamin D for bone health and fracture prevention. Curr Osteoporos Rep 2006; 4: 96-102.
13. Laaksi I. Vitamin D and respiratory infection in adults. Proc Nutr Soc 2012; 71: 90-7.
14. Holick MF, Chen TC. Vitamin D deficiency: a worldwide problem with health consequences. Am J Clin Nutr 2008; 87: 1080-6.
15. Borges MC, Martini LA, Rogero MM. Current perspectives on vitamin D, immune system, and chronic diseases. Nutrition 2011; 27: 399-404.
16. Kulie T, Groff A, Redmer J, Hounshell J, Schrager S. Vitamin D: an evidence-based review. J Am Board Fam Med 2009; 22: 698-706.
17. Bordelon P, Ghetu MV, Langan RC. Recognition and management of vitamin D deficiency. Am Fam Physician 2009; 80: 841-6.
18. Azziz R, Woods KS, Reyna R, Key TJ, Knochenhauer ES, Yildiz BO. The prevalence and features of the polycystic ovary syndrome in an unselected population. J Clin Endocrinol Metab 2004; 89: 2745-9.
19. Ott J, Wattar L, Kurz C, Seemann R, Huber JC, Mayerhofer K, et al. Parameters for calcium metabolism in women with polycystic ovary syndrome who undergo clomiphene citrate stimulation: a prospective cohort study. Eur J Endocrinol 2012; 166: 897-902.
20. Rashidi B, Haghollahi F, Shariat M, Zayerii F. The effects of calcium-vitamin D and metformin on polycystic ovary syndrome: a pilot study. Taiwan J Obstet Gynecol 2009; 48: 142-7.
21. Irani M, Merhi Z. Role of vitamin D in ovarian physiology and its implication in reproduction: a systematic review. Fertil Steril 2014; 102: 460-8.
22. Reyman M, Verrijn Stuart AA, van Summeren M, Rakhshandehroo M, Nuboer R, de Boer FK, et al. Vitamin D deficiency in childhood obesity is associated with high levels of circulating inflammatory mediators, and low insulin sensitivity. Int J Obes (Lond) 2014; 38: 46-52.
23. Thomson RL, Spedding S, Brinkworth GD, Noakes M, Buckley JD. Seasonal effects on vitamin D status influence outcomes of lifestyle intervention in overweight and obese women with polycystic ovary syndrome. Fertil Steril 2013; 99: 1779-85.
24. Belenchia AM, Tosh AK, Hillman LS, Peterson CA. Correcting vitamin D insufficiency improves insulin sensitivity in obese adolescents: a randomized controlled trial. Am J Clin Nutr 2013; 97: 774-81.
25. Moini A, Shirzad N, Ahmadzadeh M, Hosseini R, Hosseini L, Sadatmahalleh SJ. Comparison of 25-hydroxyvitamin D and Calcium Levels between Polycystic Ovarian Syndrome and Normal Women. Int J Fertil Steril 2015; 9: 1-8.
26. Grundmann M, von Versen-Höynck F. Vitamin D - roles in women's reproductive health? Reprod Biol Endocrinol 2011; 9: 146.
27. Merhi ZO, Seifer DB, Weedon J, Adeyemi O, Holman S, Anastos K, et al. Circulating vitamin D correlates with serum antimüllerian hormone levels in late-reproductive-aged women: Women's Interagency HIV Study. Fertil Steril 2012; 98: 228-34.
28. Thibeault D, Caron N, Djiana R, Kremer R, Blank D. Development and optimization of simplified LC-MS/MS quantification of 25-hydroxyvitamin D using protein precipitation combined with on-line solid phase extraction (SPE). J Chromatogr B Analyt Technol Biomed Life Sci 2012; 883-884: 120-7.
29. Paffoni A, Somigliana E, Vigano' P, Benaglia L, Cardellicchio L, Pagliardini L, et al. Vitamin D status in women with uterine leiomyomas. J Clin Endocrinol Metab 2013; 98: E1374-8.
30. Halder SK, Osteen KG, Al-Hendy A. Vitamin D3 inhibits expression and activities of matrix metalloproteinase-2 and -9 in human uterine fibroid cells. Hum Reprod 2013; 28: 2407-16.
31. Rudick BJ, Ingles SA, Chung K, Stanczyk FZ, Paulson RJ, Bendikson KA. Influence of vitamin D levels on in vitro fertilization outcomes in donor-recipient cycles. Fertil Steril 2014; 101: 447-52.
32. Ozkan S, Jindal S, Greenseid K, Shu J, Zeitlian G, Hickmon C, et al. Replete vitamin D stores predict reproductive success following in vitro fertilization. Fertil Steril 2010; 94: 1314-9.
33. Anifandis GM, Dafopoulos K, Messini CI, Chalvatzas N, Liakos N, Pournaras S, et al. Prognostic value of follicular fluid 25-OH vitamin D and glucose levels in the IVF outcome. Reprod Biol Endocrinol 2010; 8: 91.
34. Franasiak JM, Molinaro TA, Dubell EK, Scott KL, Ruiz AR, Forman EJ, et al. Vitamin D levels do not affect IVF outcomes following the transfer of euploid blastocysts. Am J Obstet Gynecol 2015; 212: 315.e1-6.
35. Blomberg Jensen M, Bjerrum PJ, Jessen TE, Nielsen JE, Joensen UN, Olesen IA, et al. Vitamin D is positively associated with sperm motility and increases intracellular calcium in human spermatozoa. Hum Reprod 2011; 26: 1307-17.
36. Ramlau-Hansen CH, Moeller UK, Bonde JP, Olsen J, Thulstrup AM. Are serum levels of vitamin D associated with semen quality? Results from a cross-sectional study in young healthy men. Fertil Steril 2011; 95: 1000-4.
37. Lee DM, Tajar A, Pye SR, Boonen S, Vanderschueren D, Bouillon R, et al. Association of hypogonadism with vitamin D status: the European Male Ageing Study. Eur J Endocrinol 2012; 166: 77-85.
38. Nimptsch K, Platz EA, Willett WC, Giovannucci E. Association between plasma 25-OH vitamin D and testosterone levels in men. Clin Endocrinol (Oxf) 2012; 77: 106-12.
39. Foresta C, Selice R, Di Mambro A, Strapazzon G. Testiculopathy and vitamin D insufficiency. Lancet 2010; 376: 1301.
40. Blomberg Jensen M, Jørgensen A, Nielsen JE, Bjerrum PJ, Skalkam M, Petersen JH, et al. Expression of the vitamin D metabolizing enzyme CYP24A1 at the annulus of human spermatozoa may serve as a novel marker of semen quality. Int J Androl 2012; 35: 499-510.

Toplam 40 adet kaynakça vardır.

Ayrıntılar

Birincil Dil	İngilizce
Konular	Kadın Hastalıkları ve Doğum
Bölüm	Review Article
Yazarlar	Özgür Deniz Turan
Yayımlanma Tarihi	31 Ağustos 2018
Yayımlandığı Sayı	Yıl 2018 Cilt: 19 Sayı: 2

Kaynak Göster

EndNote	Turan ÖD (01 Ağustos 2018) Vitamin D Level and Infertility. Meandros Medical And Dental Journal 19 2 106–110.

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