Öz
Extracranial meningiomas are rare tumors that occur in soft tissue or skin on the scalp and along the vertebral axis. The etiology of extracranial meningiomas is unknown, although four hypotheses have been postulated according to World Health Organization: (i) meningothelial cells carried along nerve sheaths as they exit the skull or vertebral column; (ii) ectopic arachnoidal cap cells; (iii) meningothelial cells displaced during trauma, and (iv) pluripotent mesenchymal cells capable of under going meningothelial differentiation or metaplasia. Extracranial meningiomas can be presented at all ages, with bimodal peaks occurring in the second decade of life and in the fifth to seventh decades. There is a slight female predominance. Located swelling in the neck for almost a year, 46-year-old female patient was made mass excision. Macroscopically the mass was 1 cm in greatest dimension, nodular in appearance, cross-sectional face-cream-white color and solid. In microscopic examination, tumor, composed of large oval-round nucleated cells and hyaline stroma were observed. Tumor surrounding thin fibrous pseudocapsule and a plurality of peripheral nerve sections were observed around it. In the stroma psammom body like calcifications were observed. Tumor cells were positive for vimentin, S100, progesterone receptor, cytokeratin and focally epithelial membrane antigen; and negative for glial fibrillary acidic protein, and actin. Based on these findings the patient was diagnosed as extracranial meningioma. Slow growing and with very good prognosis of these tumors, surgical excision is the treatment of choice and do not require further treatment. In the differential diagnosis of soft tissue tumors, extracranial meningiomas should always be considered. It can be skipped because it is rare, so we have found the value to present this case.
Anahtar Kelimeler
Kaynakça
- 1. Maeng JW, Kim YH, Seo J, Kim SW. Primary extracranial meningioma presenting as a cheek mass. Clin Exp Otorhinolaryngol 2013; 6: 266-8.
- 2. Panjvani SI, Gandhi MB, Sarvaiya AN, Chaudhari BR, Gupta GS. An extracranial invasive meningioma mimicking malignant bone tumor - "carpet meningioma". J of Cli Diag Res 2013; 7: 1159-62.
- 3. Baek BJ, Shin JM, Lee CK, Lee JH, Lee KH. Atypical primary meningioma in the nasal septum with malignant transformation and distant metastasis. BMC Cancer 2012; 12: 275.
- 4. Iaconetta G, Santella A, Friscia M, Abbate V, Califano L. Extracranial primary and secondary meningiomas. Int J Oral Maxillofac Surg 2012; 41: 211-7.
- 5. Rushing EJ, Bouffard JP, McCall S, Olsen C, Mena H, Sandberg GD, et al. Primary extracranial meningiomas: an analysis of 146 cases. Head Neck Pathol 2009; 3: 116-30.
- 6. Fletcher CDM, Bridge JA, Hogendoorn PCW, Mertens F, eds. WHO Classificiation of Tumours of Soft Tissue and Bone. Lyon: International Agency for Research on Cancer; 2013. pp. 182-3.
- 7. Miedema JR, Zedek D. Cutaneous meningioma. Arch Pathol Lab Med 2012; 136: 208-11.
- 8. Possanzini P, Pipolo C, Romagnoli S, Falleni M, Moneghini L, Braidotti P, et al. Primary extra-cranial meningioma of head and neck: clinical, histopathological and immunohistochemical study of three cases. Acta Otorhinolaryngol Ital 2012; 32: 336-8.
- 9. Tuncay IC, Güler UO, Vural C, Akgün RC, Demirörs H, Kuru I. Primary extracranial meningioma of the lower limb. Eklem Hastalik Cerrahisi 2011; 22: 114-7.
- 10. Bruner JM, Tien RD, Enterline DS. Tumors of the meninges and related tissues. In: Russell and Rubinsteins Pathology of Tumors of the Nervous System (Bigner DD, McLendon RE, Bruner JM, eds.). Arnold Press, London, 1998, pp. 69-139.
Öz
Kaynakça
- 1. Maeng JW, Kim YH, Seo J, Kim SW. Primary extracranial meningioma presenting as a cheek mass. Clin Exp Otorhinolaryngol 2013; 6: 266-8.
- 2. Panjvani SI, Gandhi MB, Sarvaiya AN, Chaudhari BR, Gupta GS. An extracranial invasive meningioma mimicking malignant bone tumor - "carpet meningioma". J of Cli Diag Res 2013; 7: 1159-62.
- 3. Baek BJ, Shin JM, Lee CK, Lee JH, Lee KH. Atypical primary meningioma in the nasal septum with malignant transformation and distant metastasis. BMC Cancer 2012; 12: 275.
- 4. Iaconetta G, Santella A, Friscia M, Abbate V, Califano L. Extracranial primary and secondary meningiomas. Int J Oral Maxillofac Surg 2012; 41: 211-7.
- 5. Rushing EJ, Bouffard JP, McCall S, Olsen C, Mena H, Sandberg GD, et al. Primary extracranial meningiomas: an analysis of 146 cases. Head Neck Pathol 2009; 3: 116-30.
- 6. Fletcher CDM, Bridge JA, Hogendoorn PCW, Mertens F, eds. WHO Classificiation of Tumours of Soft Tissue and Bone. Lyon: International Agency for Research on Cancer; 2013. pp. 182-3.
- 7. Miedema JR, Zedek D. Cutaneous meningioma. Arch Pathol Lab Med 2012; 136: 208-11.
- 8. Possanzini P, Pipolo C, Romagnoli S, Falleni M, Moneghini L, Braidotti P, et al. Primary extra-cranial meningioma of head and neck: clinical, histopathological and immunohistochemical study of three cases. Acta Otorhinolaryngol Ital 2012; 32: 336-8.
- 9. Tuncay IC, Güler UO, Vural C, Akgün RC, Demirörs H, Kuru I. Primary extracranial meningioma of the lower limb. Eklem Hastalik Cerrahisi 2011; 22: 114-7.
- 10. Bruner JM, Tien RD, Enterline DS. Tumors of the meninges and related tissues. In: Russell and Rubinsteins Pathology of Tumors of the Nervous System (Bigner DD, McLendon RE, Bruner JM, eds.). Arnold Press, London, 1998, pp. 69-139.
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Konular | Patoloji |
| Bölüm | Olgu Sunumu |
| Yazarlar | |
| Yayımlanma Tarihi | 31 Ağustos 2018 |
| Yayımlandığı Sayı | Yıl 2018 Cilt: 19 Sayı: 2 |