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Confusion of Insulinoma’s Neuroglycopenic Symptoms with Epilepsy, Two Case Presentation and a Review of Literature

Yıl 2018, Cilt: 19 Sayı: 4, 357 - 359, 31.12.2018

Öz

Insulinoma is a pancreatic endocrine tumour which origins from beta cells and characterized by excessive insulin secretion and hypoglycemia due to this. Symptoms seen in hypoglycemia are due to brain’s lack of glucose (neuroglycopenia) such as somnolence, irritability, confusion, abnormal behaviour, epileptic seizure and even coma. In this study, we presented two insulinoma cases who applied to our clinic with neuroglycopenic symptoms. Patients followed up with epilepsy diagnosis were referred to us because of low blood glucose rates. Hyperinsulinemic hypoglycemia in the prolonged fasting test and a mass in pancreas were detected in both patients and so they were diagnosed as insulinoma. The mass was excised by laparoscopic ways in surgical clinic and patients clinic were completely recovered postoperative. In conclusion, it is necessary to determine whether there is an underlying organic brain lesion or a metabolic condition in order to prevent long-term use of unnecessary antiepileptic in patients presenting with seizures

Kaynakça

  • 1. Vig S, Lewis M, Foster KJ, Stacey-Clear A. Lessons to be learned: a case study approach insulinoma presenting as a change in personality. *J R Soc Promot Health* 2001; 121: 56-61.
  • 2. Burns AR, Dackiw AP. Insulinoma. *Curr Treat Options Oncol* 2003; 4: 309-17.
  • 3. Imad H, Zelano J, Kumlien E. Hypoglycemia and risk of seizures: a retrospective cross-sectional study. *Seizure* 2015; 25: 147-9.
  • 4. Alış H, Akın BV, Kapan S, Turhan AN, Aygün E. Pankreasın Endokrin Tümörlerinden İnsülinoma: Olgu sunumu. *Bakırköy Tıp Dergisi* 2005; 1: 33-5.
  • 5. Brentjens R, Saltz L. Islet cell tumors of the pancreas. *Surg Clin North Am* 2001; 82: 527-42.
Yıl 2018, Cilt: 19 Sayı: 4, 357 - 359, 31.12.2018

Öz

Kaynakça

  • 1. Vig S, Lewis M, Foster KJ, Stacey-Clear A. Lessons to be learned: a case study approach insulinoma presenting as a change in personality. *J R Soc Promot Health* 2001; 121: 56-61.
  • 2. Burns AR, Dackiw AP. Insulinoma. *Curr Treat Options Oncol* 2003; 4: 309-17.
  • 3. Imad H, Zelano J, Kumlien E. Hypoglycemia and risk of seizures: a retrospective cross-sectional study. *Seizure* 2015; 25: 147-9.
  • 4. Alış H, Akın BV, Kapan S, Turhan AN, Aygün E. Pankreasın Endokrin Tümörlerinden İnsülinoma: Olgu sunumu. *Bakırköy Tıp Dergisi* 2005; 1: 33-5.
  • 5. Brentjens R, Saltz L. Islet cell tumors of the pancreas. *Surg Clin North Am* 2001; 82: 527-42.
Toplam 5 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Endokrinoloji
Bölüm Olgu Sunumu
Yazarlar

Feyzi Gökosmanoğlu

Ramis Çolak

Mehmet Hulusi Atmaca

Yayımlanma Tarihi 31 Aralık 2018
Yayımlandığı Sayı Yıl 2018 Cilt: 19 Sayı: 4

Kaynak Göster

EndNote Gökosmanoğlu F, Çolak R, Atmaca MH (01 Aralık 2018) Confusion of Insulinoma’s Neuroglycopenic Symptoms with Epilepsy, Two Case Presentation and a Review of Literature. Meandros Medical And Dental Journal 19 4 357–359.