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Yıl 2024, Cilt: 41 Sayı: 4, 786 - 789, 31.12.2024

Hulya Arık , Buket Baddal , Kaya Süer , Tutku Aksoy , Yaren Doğramacıoğlu , Gökay Karaça

Öz

Kaynakça

  • 1. Nmadu YW, Le MM, Aremu OG, Chen KY, Rappoport AS. Mild Encephalopathy with reversible splenial lesion (MERS) in a child with influenza. Cureus. 2023; 15(12):e50838.
  • 2. Notebaert A, Willems J, Coucke L, Van Coster R, Verhelst H. Expanding the spectrum of MERS type 2 lesions, a particular form of encephalitis. Pediatr Neurol. 2013;48(2):135-8.
  • 3. Okamoto T, Sato Y, Yamazaki T, Hayashi A. Clinically mild encephalitis/encephalopathy with a reversible splenial lesion associated with febrile urinary tract infection. Eur J Pediatr. 2014;173(4):533-6.
  • 4. Saraya T. Mycoplasma pneumoniae infection: Basics. J. Gen. Fam. Med. 2017;18(3), 118-125.
  • 5. Woo MH, Shin JW. Acute brainstem encephalitis associated with Mycoplasma pneumoniae in an adult: A case report. Encephalitis. 2021;1(4), 120-123.
  • 6. Takanashi J, Imamura A, Hayakawa F, Terada H. Differences in the time course of splenial and white matter lesions in clinically mild encephalitis/encephalopathy with a reversible splenial lesion (MERS). J Neurol Sci. 2010;292(1-2):24-7.
  • 7. Talukder NT, Feezel A, Lankford JE. Mild encephalitis/encephalopathy with a reversible splenial lesion associated with systemic Mycoplasma pneumoniae infection in North America: a case report. J Med Case Rep. 2022;16(1):74.
  • 8. Yuan ZF, Shen J, Mao SS, Yu YL, Xu L, Jiang PF, et al. Clinically mild encephalitis/encephalopathy with a reversible splenial lesion associated with Mycoplasma pneumoniae infection. BMC Infect Dis. 2016;16:230.
  • 9. Sadohara M, Arai T, Matsuura K. Clinically mild encephalitis/encephalopathy with reversible splenial lesion (MERS) associated with Mycoplasma pneumoniae pneumonia: An adult case and review of the literature. Clin Case Rep. 2020;8(12):2955-2961.
  • 10. Ueda N, Minami S, Akimoto M. Mycoplasma pneumoniae-associated mild encephalitis/encephalopathy with a reversible splenial lesion: report of two pediatric cases and a comprehensive literature review. BMC Infect Dis. 2016;16(1):671.

A rare case of mild encephalitis/encephalopathy with reversible splenial lesion associated with Mycoplasma pneumoniae in an adult male

Yıl 2024, Cilt: 41 Sayı: 4, 786 - 789, 31.12.2024

Hulya Arık , Buket Baddal , Kaya Süer , Tutku Aksoy , Yaren Doğramacıoğlu , Gökay Karaça

Öz

Mild encephalitis/encephalopathy with reversible splenial lesion (MERS) is a clinically mild, radiologically reversible clinical condition. MERS associated with Mycoplasma pneumoniae is rare and the diagnosis can be challenging. In this case report, an 18-year-old male patient with a history of travel from Saudi Arabia is presented with high fever, cough, headache, joint pain, nausea and vomiting. He was referred to the emergency department with increased tendency to sleep and a preliminary diagnosis of encephalitis. On physical examination, he was afebrile, hypotensive and bradycardic. Macular rashes on the chest and nystagmus in the right eye were observed. Meningeal irritation findings and Babinski sign were negative. Polymerase chain reaction (PCR) of the patient’s nasopharyngeal swab specimen revealed Mycoplasma pneumoniae. Cerebrospinal fluid (CSF) analysis showed pleocytosis with polymorphonuclear leukocyte (PMN) dominance and elevated total protein. M. pneumoniae was undetected in CSF via PCR. Cranial magnetic resonance imaging revealed a well-defined, oval-shaped lesion at the midline level of splenium of the corpus callosum. The patient was administered with intravenous ceftriaxone, moxifloxacin and a single dose of hydroxycobalamin. On day 2 of treatment, symptoms improved significantly and the patient was successfully discharged on day 7 upon clinical recovery. This report highlights that molecular tests are invaluable for the detection of rare pathogens in MERS cases.

Anahtar Kelimeler

Mycoplasma pneumoniae MERS molecular detection corpus callosum neuroimaging

Kaynakça

  • 1. Nmadu YW, Le MM, Aremu OG, Chen KY, Rappoport AS. Mild Encephalopathy with reversible splenial lesion (MERS) in a child with influenza. Cureus. 2023; 15(12):e50838.
  • 2. Notebaert A, Willems J, Coucke L, Van Coster R, Verhelst H. Expanding the spectrum of MERS type 2 lesions, a particular form of encephalitis. Pediatr Neurol. 2013;48(2):135-8.
  • 3. Okamoto T, Sato Y, Yamazaki T, Hayashi A. Clinically mild encephalitis/encephalopathy with a reversible splenial lesion associated with febrile urinary tract infection. Eur J Pediatr. 2014;173(4):533-6.
  • 4. Saraya T. Mycoplasma pneumoniae infection: Basics. J. Gen. Fam. Med. 2017;18(3), 118-125.
  • 5. Woo MH, Shin JW. Acute brainstem encephalitis associated with Mycoplasma pneumoniae in an adult: A case report. Encephalitis. 2021;1(4), 120-123.
  • 6. Takanashi J, Imamura A, Hayakawa F, Terada H. Differences in the time course of splenial and white matter lesions in clinically mild encephalitis/encephalopathy with a reversible splenial lesion (MERS). J Neurol Sci. 2010;292(1-2):24-7.
  • 7. Talukder NT, Feezel A, Lankford JE. Mild encephalitis/encephalopathy with a reversible splenial lesion associated with systemic Mycoplasma pneumoniae infection in North America: a case report. J Med Case Rep. 2022;16(1):74.
  • 8. Yuan ZF, Shen J, Mao SS, Yu YL, Xu L, Jiang PF, et al. Clinically mild encephalitis/encephalopathy with a reversible splenial lesion associated with Mycoplasma pneumoniae infection. BMC Infect Dis. 2016;16:230.
  • 9. Sadohara M, Arai T, Matsuura K. Clinically mild encephalitis/encephalopathy with reversible splenial lesion (MERS) associated with Mycoplasma pneumoniae pneumonia: An adult case and review of the literature. Clin Case Rep. 2020;8(12):2955-2961.
  • 10. Ueda N, Minami S, Akimoto M. Mycoplasma pneumoniae-associated mild encephalitis/encephalopathy with a reversible splenial lesion: report of two pediatric cases and a comprehensive literature review. BMC Infect Dis. 2016;16(1):671.
Toplam 10 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Bulaşıcı Hastalıklar
Bölüm Case Report
Yazarlar

Hulya Arık 0009-0009-0085-7470

Buket Baddal 0000-0003-3319-2179

Kaya Süer 0000-0002-2565-3425

Tutku Aksoy 0009-0000-0106-5402

Yaren Doğramacıoğlu 0009-0002-1887-2678

Gökay Karaça 0000-0002-6450-4684

Yayımlanma Tarihi 31 Aralık 2024
Gönderilme Tarihi 28 Mayıs 2024
Kabul Tarihi 15 Kasım 2024
Yayımlandığı Sayı Yıl 2024 Cilt: 41 Sayı: 4

Kaynak Göster

APA Arık, H., Baddal, B., Süer, K., Aksoy, T., vd. (2024). A rare case of mild encephalitis/encephalopathy with reversible splenial lesion associated with Mycoplasma pneumoniae in an adult male. Deneysel Ve Klinik Tıp Dergisi, 41(4), 786-789.
AMA Arık H, Baddal B, Süer K, Aksoy T, Doğramacıoğlu Y, Karaça G. A rare case of mild encephalitis/encephalopathy with reversible splenial lesion associated with Mycoplasma pneumoniae in an adult male. J. Exp. Clin. Med. Aralık 2024;41(4):786-789.
Chicago Arık, Hulya, Buket Baddal, Kaya Süer, Tutku Aksoy, Yaren Doğramacıoğlu, ve Gökay Karaça. “A Rare Case of Mild encephalitis/Encephalopathy With Reversible Splenial Lesion Associated With Mycoplasma Pneumoniae in an Adult Male”. Deneysel Ve Klinik Tıp Dergisi 41, sy. 4 (Aralık 2024): 786-89.
EndNote Arık H, Baddal B, Süer K, Aksoy T, Doğramacıoğlu Y, Karaça G (01 Aralık 2024) A rare case of mild encephalitis/encephalopathy with reversible splenial lesion associated with Mycoplasma pneumoniae in an adult male. Deneysel ve Klinik Tıp Dergisi 41 4 786–789.
IEEE H. Arık, B. Baddal, K. Süer, T. Aksoy, Y. Doğramacıoğlu, ve G. Karaça, “A rare case of mild encephalitis/encephalopathy with reversible splenial lesion associated with Mycoplasma pneumoniae in an adult male”, J. Exp. Clin. Med., c. 41, sy. 4, ss. 786–789, 2024.
ISNAD Arık, Hulya vd. “A Rare Case of Mild encephalitis/Encephalopathy With Reversible Splenial Lesion Associated With Mycoplasma Pneumoniae in an Adult Male”. Deneysel ve Klinik Tıp Dergisi 41/4 (Aralık 2024), 786-789.
JAMA Arık H, Baddal B, Süer K, Aksoy T, Doğramacıoğlu Y, Karaça G. A rare case of mild encephalitis/encephalopathy with reversible splenial lesion associated with Mycoplasma pneumoniae in an adult male. J. Exp. Clin. Med. 2024;41:786–789.
MLA Arık, Hulya vd. “A Rare Case of Mild encephalitis/Encephalopathy With Reversible Splenial Lesion Associated With Mycoplasma Pneumoniae in an Adult Male”. Deneysel Ve Klinik Tıp Dergisi, c. 41, sy. 4, 2024, ss. 786-9.
Vancouver Arık H, Baddal B, Süer K, Aksoy T, Doğramacıoğlu Y, Karaça G. A rare case of mild encephalitis/encephalopathy with reversible splenial lesion associated with Mycoplasma pneumoniae in an adult male. J. Exp. Clin. Med. 2024;41(4):786-9.

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