Araştırma Makalesi
Yıl 2023,
Cilt: 15 Sayı: 2, 610 - 614, 14.07.2023
Öz
Bu makale 3B baskılanmış bir mikro kanalada damlacık oluşumunun sıvı basıncı ile olan ilişkisini inceler. SLA (stereyolitografi) 3B yazıcı ile reçineden şefff mikroakışkan çip imal edilmiştir. Yağ içinde su mikro damlacıkarı sıvı odaklama tasarımında oluşturulmuştur. Yağ ve su girişleri sabit basınç kayanağı ile sürülmüştür. Mikroakışkan çipin mikrodamlacık oluşturma başarımı mikroskop vasıtasıyla gözlenmiştir. Mikrodamlacıkların boyutları sıvı basıncına göre belirlenmiştir.
Anahtar Kelimeler
Destekleyen Kurum
Kırıkkale Üniversitesi BAP
Proje Numarası
2021/043
Kaynakça
- Bhargava, Krisna C, Bryant Thompson, and Noah Malmstadt (2014) Discrete elements for 3D microfluidics. Proceedings of the National Academy of Sciences 111(42):15013-15018.
- Bilican, İsmail, and Mustafa Tahsin Guler (2020) Assessment of PMMA and polystyrene-based microfluidic chips fabricated using CO2 laser machining. Applied Surface Science 534:147642.
- Donvito, Lidia, et al. (2015) Experimental validation of a simple, low-cost, T-junction droplet generator fabricated through 3D printing. Journal of Micromechanics and Microengineering 25(3):035013.
- Ghorbanpoor, Hamed, et al. (2022) A fully integrated rapid on-chip antibiotic susceptibility test–A case study for Mycobacterium smegmatis. Sensors and Actuators A: Physical 339:113515.
- Guler, M Tahsin (2022) Fabricating plasma bonded microfluidic chips by CO2 laser machining of PDMS by the application of viscoelastic particle focusing and droplet generation. Journal of Manufacturing Processes 73:260-268.
- Guler, Mustafa Tahsin, Murat Inal, and Ismail Bilican (2021) CO2 laser machining for microfluidics mold fabrication from PMMA with applications on viscoelastic focusing, electrospun nanofiber production, and droplet generation. Journal of Industrial and Engineering Chemistry 98:340-349.
- Isiksacan, Ziya, et al. (2016) Rapid fabrication of microfluidic PDMS devices from reusable PDMS molds using laser ablation. Journal of Micromechanics and Microengineering 26(3):035008.
- Kecili, Seren, and H Cumhur Tekin (2020) Adhesive bonding strategies to fabricate the high-strength and transparent 3D printed microfluidic device. Biomicrofluidics 14(2):024113.
- Kim, Tyson N, et al. (2005) Femtosecond laser-drilled capillary integrated into a microfluidic device. Applied Physics Letters 86(20):201106.
- Kotz, Frederik, et al. (2018) Highly fluorinated methacrylates for optical 3D printing of microfluidic devices. Micromachines 9(3):115.
- Lepowsky, Eric, Reza Amin, and Savas Tasoglu (2018) Assessing the reusability of 3D-printed photopolymer microfluidic chips for urine processing. Micromachines 9(10):520.
- Li, Zhenqing, et al. (2023) Lower fluidic resistance of double-layer droplet continuous flow PCR microfluidic chip for rapid detection of bacteria. Analytica Chimica Acta 1251:340995.
- Morgan, Alex JL, et al. (2016) Simple and versatile 3D printed microfluidics using fused filament fabrication. PloS one 11(4):e0152023.
- Nelson, Matt D, Nirupama Ramkumar, and Bruce K Gale (2019) Flexible, transparent, sub-100 μm microfluidic channels with fused deposition modeling 3D-printed thermoplastic polyurethane. Journal of Micromechanics and Microengineering 29(9):095010.
- Oliveira, Beatriz, et al. (2020) Fast prototyping microfluidics: integrating droplet digital lamp for absolute quantification of cancer biomarkers. Sensors 20(6):1624.
- Tsuda, Soichiro, et al. (2015) Customizable 3D printed ‘plug and play’millifluidic devices for programmable fluidics. PLoS One 10(11):e0141640.
- Wu, Jiandong, et al. (2017) Lab-on-a-chip platforms for detection of cardiovascular disease and cancer biomarkers. Sensors 17(12):2934.
Yıl 2023,
Cilt: 15 Sayı: 2, 610 - 614, 14.07.2023
Öz
This paper reports the droplet formation performance of a 3D-printed microfluidic chip according to fluid pressure. SLA (stereolithography) 3D printer was employed for manufacturing the transparent microfluidic chip from resin. Water in oil microdroplets was produced on a flow-focusing design. Oil and water inlets were driven by a constant pressure source. The droplet production performance of the microfluidic chip was monitored through a microscope. The size of water droplets was determined according to pressure values.
Anahtar Kelimeler
Proje Numarası
2021/043
Kaynakça
- Bhargava, Krisna C, Bryant Thompson, and Noah Malmstadt (2014) Discrete elements for 3D microfluidics. Proceedings of the National Academy of Sciences 111(42):15013-15018.
- Bilican, İsmail, and Mustafa Tahsin Guler (2020) Assessment of PMMA and polystyrene-based microfluidic chips fabricated using CO2 laser machining. Applied Surface Science 534:147642.
- Donvito, Lidia, et al. (2015) Experimental validation of a simple, low-cost, T-junction droplet generator fabricated through 3D printing. Journal of Micromechanics and Microengineering 25(3):035013.
- Ghorbanpoor, Hamed, et al. (2022) A fully integrated rapid on-chip antibiotic susceptibility test–A case study for Mycobacterium smegmatis. Sensors and Actuators A: Physical 339:113515.
- Guler, M Tahsin (2022) Fabricating plasma bonded microfluidic chips by CO2 laser machining of PDMS by the application of viscoelastic particle focusing and droplet generation. Journal of Manufacturing Processes 73:260-268.
- Guler, Mustafa Tahsin, Murat Inal, and Ismail Bilican (2021) CO2 laser machining for microfluidics mold fabrication from PMMA with applications on viscoelastic focusing, electrospun nanofiber production, and droplet generation. Journal of Industrial and Engineering Chemistry 98:340-349.
- Isiksacan, Ziya, et al. (2016) Rapid fabrication of microfluidic PDMS devices from reusable PDMS molds using laser ablation. Journal of Micromechanics and Microengineering 26(3):035008.
- Kecili, Seren, and H Cumhur Tekin (2020) Adhesive bonding strategies to fabricate the high-strength and transparent 3D printed microfluidic device. Biomicrofluidics 14(2):024113.
- Kim, Tyson N, et al. (2005) Femtosecond laser-drilled capillary integrated into a microfluidic device. Applied Physics Letters 86(20):201106.
- Kotz, Frederik, et al. (2018) Highly fluorinated methacrylates for optical 3D printing of microfluidic devices. Micromachines 9(3):115.
- Lepowsky, Eric, Reza Amin, and Savas Tasoglu (2018) Assessing the reusability of 3D-printed photopolymer microfluidic chips for urine processing. Micromachines 9(10):520.
- Li, Zhenqing, et al. (2023) Lower fluidic resistance of double-layer droplet continuous flow PCR microfluidic chip for rapid detection of bacteria. Analytica Chimica Acta 1251:340995.
- Morgan, Alex JL, et al. (2016) Simple and versatile 3D printed microfluidics using fused filament fabrication. PloS one 11(4):e0152023.
- Nelson, Matt D, Nirupama Ramkumar, and Bruce K Gale (2019) Flexible, transparent, sub-100 μm microfluidic channels with fused deposition modeling 3D-printed thermoplastic polyurethane. Journal of Micromechanics and Microengineering 29(9):095010.
- Oliveira, Beatriz, et al. (2020) Fast prototyping microfluidics: integrating droplet digital lamp for absolute quantification of cancer biomarkers. Sensors 20(6):1624.
- Tsuda, Soichiro, et al. (2015) Customizable 3D printed ‘plug and play’millifluidic devices for programmable fluidics. PLoS One 10(11):e0141640.
- Wu, Jiandong, et al. (2017) Lab-on-a-chip platforms for detection of cardiovascular disease and cancer biomarkers. Sensors 17(12):2934.
Toplam 17 adet kaynakça vardır.
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Konular | Makine Mühendisliği |
| Bölüm | Makaleler |
| Yazarlar | |
| Proje Numarası | 2021/043 |
| Erken Görünüm Tarihi | 7 Temmuz 2023 |
| Yayımlanma Tarihi | 14 Temmuz 2023 |
| Gönderilme Tarihi | 21 Nisan 2023 |
| Yayımlandığı Sayı | Yıl 2023 Cilt: 15 Sayı: 2 |
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