Öz
Serumda cinko, bakir ve magnezyumun, semende ginko ve asit fosfatazin erkek infertilitesindeki 6nemini ve etkinlik derecesini arastirmak amaci ile 54 infertil ve 19 fertil olgzunun kan ve semen örnekleri incelendi. Serum ginko dtzeyi infertil gurupta, fertil guruba göre daha diistik bulundu. Semen ginko konsantrasyonu infertil olgular fertil olgulara gore olduk¢a dtisiik dtizeyde ve anlamh idi. Serum semen ginko dtizeyleri arasinda infertil olgularda korelasyon mevcut degildi. Serum bakir diizeyi infertil olgularda, fertil olgulara g6 yuksek dtizeyde idi ve fark anlamli idi. Serum magnezyum konsantrasyonu ile sperm sayisi ve motilitesi arasinda bir korelasyona rastlanmadi. Infertil olgularda serum ve semen ¢cinko diizeyi ile sesikrum bakir diizeyi arasmda negatif bir korelasyon mevcuttu. Ayni ge- kilde serum bakir dtizeyi ile seminal asit fosfataz dizeyi arasinda da pozitif korelasyon mevcuttu. Seminal asit fosfataz duzeyi infertil olgularda fertil olgulara gore daha yiiksekti ve sonug anlamlh idi. Sperm
sayisi ve motilitesi ile seminal asit fosfataz duzeyi arasinda negatif bir korelasyon mevcut olup sonug anlamll idi. Infertil kronik prostatitli olgularda serum ve semen cinko diizeyleri anlaml derecede dtbulunurken asit fosfataz dtzeylerinde fark pézlenmedi. Serum bakir diizeyi prostatitli gurupta, nonprostatitli guruba gore yuksek bulunurken magnezyum yéntinden anlamh bir sonuca rastlanmadi.
Etik Beyan
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Destekleyen Kurum
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Proje Numarası
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Teşekkür
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Kaynakça
- 1. Swerdloff RS Overstreet JW Sokol RZ Rajfer J : Infertility in the male. An. Med. 103 (6pt, 1) : 906-919, 1985.
- 2. Skandhan KP Skandhan S Mehta YB : Semen electrolytes in normal and in- fertile subjects. Il. Zinc, Experientia. 34/11 : 1476-1477, 1978.
- 3. Spencer H Rosaff B and Felstein : Metabolism of zinc 65 in man. Radiation Res. 24 482-442, 1965.
- 4. Reinhold JG Renaghy HA : Zinc deficiency in man. The Lancet. p : 1520-1521, June 1973.
- 5. Umeyama T Ishikawa H Takeshima H Yoshii S Koiso K : A comparative study of seminal trace elements in fertile and infertile men. Fertil. Steril. Vol. 46, No. 3, 494-499, 1986.
- 6. Lindholmer CH Eliasson R: Zinc and magnesium in human spermatozoa. Int. J. Fertil, 17 : 153-160, 1972.
- 7. Mbizyo MT Nyazema NZ Chimbira THK : Seminal plasma zinc levels in fertile and infertile men. South Af. Med. Jour. 71 : 266-169, 1987.
- 8. Pleban PA Mei DS: Trace elements in human seminal and spermatozoa, Clinica Chimica, Acta. 133 : 48-50, 1983.
- 9. Carole IM Mary I Vinette PR Rebecca ZS : Serum and semen zine levels in normozoospermic and oligozoospermic men. Ann, Nutr. Metab. 30 ; 213-218, 1986.
- 10. Halsted JA Smith JC : Plasma zinc in health and disease. The Lancet. 322-324, 1970.
- 11. StanwellLSmith R Thompson SG Haines AP Ward RJ Cashmore G Stedronska. J Hendry WF : A comparative study of zinc, copper, cadmium and lead levels in fertile and infertile men. Fertil. Steril. Vol : 40, No : 5, p : 670-677, 1983.
- 12. Marmar JL Katz $ Praiss DE De Benedictis TJ : Semen zinc levels in infertile and postvasectomy patients and patients with prostatitis, Fertil. Steril. 26 (11) : 1057-1059, 1975
- 13. Kesseru E Leon F : Effect of different solid metals and metallic pairs on human sperm motility. Int. J. Fertil. 19 : 81-84, 1974.
- 14. Prasad AS Oberleas D : Zinc deficiency in man. The Lancet. p: 50, July 1979.
- 15. Upadhyaya M Ribbard BK Walker SM : Seminal acid phosphatase in relation to fertility, Acta Obst. Gynecol, Scand. 65 : 49-52, 1986. 16. Nun 5 Musacchio I Epstein JA : Variations in seminal plasma constituents from fertile, and . vasectomised azoospermic men. Fertil. Steril. Vol. 23, No. 5, 357-359, 1972
- 17. Kothari LK Gupta AS Chaturvedi KC Paliwal OL : Seminal fructose and acid phosphatase in vasectomised men. Int. J. Fertil, 22; 60-62, 1977,
- 18. Anthony AC Kathryn AD Abraham TK : Monitoring zinc concentrations in seminal plasma during treatment of prostatitis and infertility. Surgical Forum. 29 644-646, 1978.
- 19. Dubin L Amelar RD : Etiologic factors in 1294 consecutive cases of male infertility. Fertil. Steril. 22 : 496-499, 1971.
- 20. William RF David BC Nancy C Neston WD: A re-appraisal of treatment in chronic bacterial prostatitis, J. Urol. 121 : 437-441, 1979
Öz
54 infertile and 19 fertile men’s blood and semen specimens were examined to understand the importance and effect of blood zinc, copper and magnesium and seminal zinc and acid phosphatase in male infertility. In the infertile group, blood zinc concentration was lower than the fertile subjects. In the infertile cases, seminal zinc concentration was quitely lower and significant than the fertile group. There was no correlation between the blood and semen zinc levels in the infertile patients. The blood copper level was higher in the infertile patients than the fertile subjects and than difference was significant. There was no correlation between the blood magnesium concentration and sperm count and motility. There was a negative correlation bet- ween zinc concentration both in blood and semen and blood copper
level in the infertile patients. Similarly, we found a positive relationship between the blood copper concentration and seminal acid phosphatase. Seminal acid phosphatase level was higher in the infertil patients than fertile subjects and that result was significant. There was a negative relationship between seminal acid phosphatase and sperm count and motility. While blood and semen zinc levels were significantly lower in the infertile males with chronic prostatitis, seminal acid phosphatase concentration was normal. We found that blood copper concentration was higher in patients with prostatitis than the patients with nonprostatitis,
but there was no significant result in magnesium concentration in these groups.
Etik Beyan
-
Destekleyen Kurum
-
Proje Numarası
-
Teşekkür
-
Kaynakça
- 1. Swerdloff RS Overstreet JW Sokol RZ Rajfer J : Infertility in the male. An. Med. 103 (6pt, 1) : 906-919, 1985.
- 2. Skandhan KP Skandhan S Mehta YB : Semen electrolytes in normal and in- fertile subjects. Il. Zinc, Experientia. 34/11 : 1476-1477, 1978.
- 3. Spencer H Rosaff B and Felstein : Metabolism of zinc 65 in man. Radiation Res. 24 482-442, 1965.
- 4. Reinhold JG Renaghy HA : Zinc deficiency in man. The Lancet. p : 1520-1521, June 1973.
- 5. Umeyama T Ishikawa H Takeshima H Yoshii S Koiso K : A comparative study of seminal trace elements in fertile and infertile men. Fertil. Steril. Vol. 46, No. 3, 494-499, 1986.
- 6. Lindholmer CH Eliasson R: Zinc and magnesium in human spermatozoa. Int. J. Fertil, 17 : 153-160, 1972.
- 7. Mbizyo MT Nyazema NZ Chimbira THK : Seminal plasma zinc levels in fertile and infertile men. South Af. Med. Jour. 71 : 266-169, 1987.
- 8. Pleban PA Mei DS: Trace elements in human seminal and spermatozoa, Clinica Chimica, Acta. 133 : 48-50, 1983.
- 9. Carole IM Mary I Vinette PR Rebecca ZS : Serum and semen zine levels in normozoospermic and oligozoospermic men. Ann, Nutr. Metab. 30 ; 213-218, 1986.
- 10. Halsted JA Smith JC : Plasma zinc in health and disease. The Lancet. 322-324, 1970.
- 11. StanwellLSmith R Thompson SG Haines AP Ward RJ Cashmore G Stedronska. J Hendry WF : A comparative study of zinc, copper, cadmium and lead levels in fertile and infertile men. Fertil. Steril. Vol : 40, No : 5, p : 670-677, 1983.
- 12. Marmar JL Katz $ Praiss DE De Benedictis TJ : Semen zinc levels in infertile and postvasectomy patients and patients with prostatitis, Fertil. Steril. 26 (11) : 1057-1059, 1975
- 13. Kesseru E Leon F : Effect of different solid metals and metallic pairs on human sperm motility. Int. J. Fertil. 19 : 81-84, 1974.
- 14. Prasad AS Oberleas D : Zinc deficiency in man. The Lancet. p: 50, July 1979.
- 15. Upadhyaya M Ribbard BK Walker SM : Seminal acid phosphatase in relation to fertility, Acta Obst. Gynecol, Scand. 65 : 49-52, 1986. 16. Nun 5 Musacchio I Epstein JA : Variations in seminal plasma constituents from fertile, and . vasectomised azoospermic men. Fertil. Steril. Vol. 23, No. 5, 357-359, 1972
- 17. Kothari LK Gupta AS Chaturvedi KC Paliwal OL : Seminal fructose and acid phosphatase in vasectomised men. Int. J. Fertil, 22; 60-62, 1977,
- 18. Anthony AC Kathryn AD Abraham TK : Monitoring zinc concentrations in seminal plasma during treatment of prostatitis and infertility. Surgical Forum. 29 644-646, 1978.
- 19. Dubin L Amelar RD : Etiologic factors in 1294 consecutive cases of male infertility. Fertil. Steril. 22 : 496-499, 1971.
- 20. William RF David BC Nancy C Neston WD: A re-appraisal of treatment in chronic bacterial prostatitis, J. Urol. 121 : 437-441, 1979
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Konular | Üroloji |
| Bölüm | Makaleler |
| Yazarlar | |
| Proje Numarası | - |
| Yayımlanma Tarihi | 31 Mart 1991 |
| Yayımlandığı Sayı | Yıl 1991 Cilt: 44 Sayı: 1 |
